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ES8106877A1 - Un procedimiento para preparar un derivado de dibenzo (a,d) ciclohepteno - Google Patents

Un procedimiento para preparar un derivado de dibenzo (a,d) ciclohepteno

Info

Publication number
ES8106877A1
ES8106877A1 ES495386A ES495386A ES8106877A1 ES 8106877 A1 ES8106877 A1 ES 8106877A1 ES 495386 A ES495386 A ES 495386A ES 495386 A ES495386 A ES 495386A ES 8106877 A1 ES8106877 A1 ES 8106877A1
Authority
ES
Spain
Prior art keywords
group
formula
image
dibenzo
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES495386A
Other languages
English (en)
Other versions
ES495386A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toa Eiyo Ltd
Original Assignee
Toa Eiyo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toa Eiyo Ltd filed Critical Toa Eiyo Ltd
Publication of ES495386A0 publication Critical patent/ES495386A0/es
Publication of ES8106877A1 publication Critical patent/ES8106877A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/14—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/64—Acyl halides
    • C07C57/72—Acyl halides containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/86—Unsaturated compounds containing keto groups containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/88—Unsaturated compounds containing keto groups containing halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN DERIVADO DE DIBENZO (A,D)-CICLOHEPTENO DE FORMULA (I), EN LA QUE R1 ES UN ATOMO DE HIDROGENO, O DE HALOGENO O UN RADICAL ALCOHILO INFERIOR; R2 Y R3 SON HIDROGENO O UN RADICAL ALCOHILO INFERIOR, Y Z ES UN RADICAL DE FORMULA *FORMULA*. CONSISTE EN LA REACCION DE CICLACION DE UN COMPUESTO DE FORMULA (II), EN LA QUE R1 Y R2 SON LOS MISMOS QUE EN LA FORMULA (I); X ES UN HIDROXIDO O UN HALOGENO, Y UNO DE LOS RADICALES Y TIENE LA FORMULA -CH2COX, Y EL OTRO ES HIDROGENO. EL PRODUCTO OBTENIDO SE PUEDE HIDROLIZAR Y ESTERIFICAR POR METODOS CONVENCIONALES. LA REACCION DE CICLACION SE PUEDE LLEVAR A CABO EN PRESENCIA DE UN AGENTE DE CONDENSACION, SI X ES UN HIDROXILO, Y EN PRESENCIA DE UN CATALIZADOR FRIEDEL-CRAFTS, SI X ES HALOGENO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIINFLAMATORIA. *FORMULA*
ES495386A 1979-09-29 1980-09-26 Un procedimiento para preparar un derivado de dibenzo (a,d) ciclohepteno Expired ES8106877A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12474179A JPS5649337A (en) 1979-09-29 1979-09-29 Dibenzo a,d cycloheptene derivative and its preparation

Publications (2)

Publication Number Publication Date
ES495386A0 ES495386A0 (es) 1981-09-01
ES8106877A1 true ES8106877A1 (es) 1981-09-01

Family

ID=14892958

Family Applications (2)

Application Number Title Priority Date Filing Date
ES495386A Expired ES8106877A1 (es) 1979-09-29 1980-09-26 Un procedimiento para preparar un derivado de dibenzo (a,d) ciclohepteno
ES498317A Granted ES498317A0 (es) 1979-09-29 1981-01-05 Un procedimiento para preparar un derivado de dibenzo (a,d)-ci-clohepteno

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES498317A Granted ES498317A0 (es) 1979-09-29 1981-01-05 Un procedimiento para preparar un derivado de dibenzo (a,d)-ci-clohepteno

Country Status (10)

Country Link
US (1) US4410716A (es)
JP (1) JPS5649337A (es)
AU (1) AU534186B2 (es)
CH (1) CH648820A5 (es)
DE (1) DE3036175A1 (es)
ES (2) ES8106877A1 (es)
FR (1) FR2468573A1 (es)
GB (1) GB2059964B (es)
IT (1) IT1209358B (es)
NL (1) NL8005398A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI730037B (zh) * 2016-01-26 2021-06-11 日商富士軟片和光純藥股份有限公司 光硬化方法，及用於該光硬化方法之化合物和組成物
CN110678500B (zh) * 2017-06-12 2022-10-14 富士胶片和光纯药株式会社 光或热固化方法及固化性树脂组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3409640A (en) * 1959-07-22 1968-11-05 Schering Corp 5-(3'-dimethylamino-2'-methyl-propyl)dibenzocycloheptenes
FR1469469A (fr) * 1965-06-18 1967-02-17 Rhone Poulenc Sa Nouveaux dérivés du dibenzocycloheptatriène et leur préparation
OA04603A (fr) * 1973-03-02 1980-06-30 Rhone Poulenc Sa Nouveaux dérivés du dibenzo [a,d] cycloheptene, leurs sels et leur préparation.
US3975437A (en) * 1973-03-02 1976-08-17 Rhone-Poulenc S.A. Dibenzo (a,d) cycloheptene derivatives
US3966820A (en) * 1974-07-05 1976-06-29 Syntex (U.S.A.) Inc. 2-Substituted-5-oxo-5H-dibenzo-[A,D]cycloheptenes, the esters and ethers thereof, having pharmaceutical activity, and methods and compositions for the use thereof
US4059611A (en) * 1975-09-08 1977-11-22 Syntex (U.S.A.) Inc. Oxidative process for the preparation of 2-(5H-dibenzo[a,d]cyclohepten-5-on-2-yl)acetic, propionic and butyric acid

Also Published As

Publication number Publication date
FR2468573B1 (es) 1982-11-19
ES8201522A1 (es) 1981-12-16
DE3036175A1 (de) 1981-04-16
FR2468573A1 (fr) 1981-05-08
ES495386A0 (es) 1981-09-01
IT1209358B (it) 1989-07-16
IT8025000A0 (it) 1980-09-29
AU6268680A (en) 1981-04-09
CH648820A5 (de) 1985-04-15
NL8005398A (nl) 1981-03-31
US4410716A (en) 1983-10-18
ES498317A0 (es) 1981-12-16
JPS5649337A (en) 1981-05-02
GB2059964B (en) 1983-05-18
AU534186B2 (en) 1984-01-12
GB2059964A (en) 1981-04-29

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