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ES8102134A1 - Procedimiento para preparar derivados de acido acetico - Google Patents

Procedimiento para preparar derivados de acido acetico

Info

Publication number
ES8102134A1
ES8102134A1 ES488651A ES488651A ES8102134A1 ES 8102134 A1 ES8102134 A1 ES 8102134A1 ES 488651 A ES488651 A ES 488651A ES 488651 A ES488651 A ES 488651A ES 8102134 A1 ES8102134 A1 ES 8102134A1
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
unsubstituted
substituted
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES488651A
Other languages
English (en)
Other versions
ES488651A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH154579A external-priority patent/CH641810A5/de
Priority claimed from CH17480A external-priority patent/CH645378A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES8102134A1 publication Critical patent/ES8102134A1/es
Publication of ES488651A0 publication Critical patent/ES488651A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C07D231/40—Acylated on said nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS DEL ACIDO ACETICO. CONSISTE EN EFECTUAR ALGUNA DE LAS SIGUIENTES OPERACIONES: 1) REACCION DE UN COMPUESTO DE FORMULA GENERAL (I), CON OTRO DE FORMULA GENERAL (II). 2) HIDROGENACION DE UN COMPUESTO DE FORMULA (III). 3) HIDROLISIS DE UN COMPUESTO (IV), O 4) HIDROGENACION DE UN COMPUESTO DE FORMULA GENERAL (V). SE OBTIENE UN COMPUESTO DE FORMULA GENERAL (VI). OPCIONALMENTE, SE SOMETE A UNA MEZCLA ISOMERICA SIN/ANTI DE UN COMPUESTO (VI) A UNA SEPARACION CROMATOGRAFICA O A UN TRATAMIENTO CON BETA-LACTAMASA, SEGUIDO DE UN AISLAMIENTO DEL ISOMERO SIN PARA OBTENER EL COMPUESTO (VI) EN ISOMERIZACION SIN. *FORMULA*
ES488651A 1979-02-16 1980-02-15 Procedimiento para preparar derivados de acido acetico Granted ES488651A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH154579A CH641810A5 (en) 1979-02-16 1979-02-16 Acetamidocephalosporanic acid derivatives, process for their preparation and pharmaceutical forms which contain them
CH17480A CH645378A5 (en) 1980-01-10 1980-01-10 Acetamidocephalosporanic acid derivatives, process for their preparation and pharmaceutical forms which contain them

Publications (2)

Publication Number Publication Date
ES8102134A1 true ES8102134A1 (es) 1980-12-16
ES488651A0 ES488651A0 (es) 1980-12-16

Family

ID=25683752

Family Applications (2)

Application Number Title Priority Date Filing Date
ES488651A Granted ES488651A0 (es) 1979-02-16 1980-02-15 Procedimiento para preparar derivados de acido acetico
ES497002A Granted ES497002A0 (es) 1979-02-16 1980-11-20 Procedimiento para preparar derivados de acido acetico

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES497002A Granted ES497002A0 (es) 1979-02-16 1980-11-20 Procedimiento para preparar derivados de acido acetico

Country Status (19)

Country Link
US (1) US4477448A (es)
AT (1) AT374806B (es)
CA (1) CA1161032A (es)
DE (1) DE3005012A1 (es)
DK (1) DK53780A (es)
ES (2) ES488651A0 (es)
FI (1) FI800381A (es)
FR (1) FR2449093A1 (es)
GB (2) GB2046734B (es)
IE (1) IE49395B1 (es)
IL (1) IL59391A (es)
IT (1) IT8047922A0 (es)
MY (1) MY8500128A (es)
NL (1) NL8000894A (es)
NZ (1) NZ192873A (es)
PH (1) PH17926A (es)
PT (1) PT70834A (es)
SE (2) SE8000982L (es)
YU (1) YU40280A (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3165922D1 (en) * 1980-03-28 1984-10-18 Biochemie Gmbh New process for the production of cephalosporin antibiotics, and novel intermediates used in such process and their production
CH648038A5 (de) * 1981-01-19 1985-02-28 Sandoz Ag 7-((carboxymethoxyimino)-1h-pyrazol-3-yl-acetyl)amino-3-desacetoxy-3-(1-methyl-1h-tetrazol-5-yl-thio)cephalosporansaeure und salze, verfahren zur herstellung und verwendung.
GB2125033B (en) * 1982-07-23 1985-08-29 Servipharm Ltd Cephalosporins
US4698338A (en) * 1986-02-19 1987-10-06 Eli Lilly And Company 7[2-(2-aminothiazol-4-yl)-2-benzyloximino]acetamido-3[4-alkyl-5-oxo-6-hydroxy-3,4-dihydro-1,2,4-triazin-3-yl]thiomethyl cephalosporins
US5688964A (en) * 1996-02-13 1997-11-18 Eastman Kodak Company Process for preparing a acylhyrazino pyrazole derivative
CA2383157A1 (en) * 1999-09-24 2001-03-29 Agro-Kanesho Co., Ltd. Insecticidal and acaricidal agents
EP2147679B1 (en) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Compositions for blood-brain barrier transport
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
CN101594878A (zh) 2006-09-18 2009-12-02 雷普特药品公司 通过给予受体相关蛋白（rap）-缀合物对肝病症的治疗
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024137A (en) * 1971-05-14 1977-05-17 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(phenyl- or naphthylacetamido)] cephalosporins

Also Published As

Publication number Publication date
US4477448A (en) 1984-10-16
DE3005012A1 (de) 1980-11-27
IE800284L (en) 1980-08-16
NZ192873A (en) 1984-07-31
GB2046734B (en) 1983-09-01
FI800381A (fi) 1980-08-17
CA1161032A (en) 1984-01-24
NL8000894A (nl) 1980-08-19
IL59391A0 (en) 1980-05-30
FR2449093B1 (es) 1983-07-29
IT8047922A0 (it) 1980-02-15
GB2117774B (en) 1984-03-21
PH17926A (en) 1985-01-31
YU40280A (en) 1983-06-30
IL59391A (en) 1983-05-15
MY8500128A (en) 1985-12-31
IE49395B1 (en) 1985-10-02
ATA78780A (de) 1983-10-15
GB2117774A (en) 1983-10-19
GB2046734A (en) 1980-11-19
FR2449093A1 (fr) 1980-09-12
GB8309730D0 (en) 1983-05-18
SE8500589D0 (sv) 1985-02-08
SE8000982L (sv) 1980-08-17
DK53780A (da) 1980-08-17
ES8203848A1 (es) 1982-04-01
PT70834A (en) 1980-03-01
AT374806B (de) 1984-06-12
ES488651A0 (es) 1980-12-16
ES497002A0 (es) 1982-04-01

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