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ES553613A0 - Un procedimiento para preparar derivados de alanil-prolina. - Google Patents

Un procedimiento para preparar derivados de alanil-prolina.

Info

Publication number
ES553613A0
ES553613A0 ES553613A ES553613A ES553613A0 ES 553613 A0 ES553613 A0 ES 553613A0 ES 553613 A ES553613 A ES 553613A ES 553613 A ES553613 A ES 553613A ES 553613 A0 ES553613 A0 ES 553613A0
Authority
ES
Spain
Prior art keywords
procedure
alanyl
preparing
prolin
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES553613A
Other languages
English (en)
Other versions
ES8801313A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of ES8801313A1 publication Critical patent/ES8801313A1/es
Publication of ES553613A0 publication Critical patent/ES553613A0/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES553613A 1984-09-01 1986-04-01 Un procedimiento para preparar derivados de alanil-prolina. Expired ES8801313A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848422165A GB8422165D0 (en) 1984-09-01 1984-09-01 Compounds

Publications (2)

Publication Number Publication Date
ES8801313A1 ES8801313A1 (es) 1988-01-01
ES553613A0 true ES553613A0 (es) 1988-01-01

Family

ID=10566163

Family Applications (6)

Application Number Title Priority Date Filing Date
ES546595A Expired ES8703418A1 (es) 1984-09-01 1985-08-30 Un procedimiento para preparar derivados heterociclicos ni- trogenados
ES553614A Expired ES8801672A1 (es) 1984-09-01 1986-04-01 Un procedimiento para preparar derivados de alanil-prolina.
ES553612A Expired ES8801312A1 (es) 1984-09-01 1986-04-01 Un procedimiento para preparar derivados de alanil-prolina.
ES553611A Expired ES8801311A1 (es) 1984-09-01 1986-04-01 Un procedimiento para preparar derivados de alamil-prolina.
ES553610A Expired ES8801310A1 (es) 1984-09-01 1986-04-01 Un procedimiento para preparar derivados de alanil-protina.
ES553613A Expired ES8801313A1 (es) 1984-09-01 1986-04-01 Un procedimiento para preparar derivados de alanil-prolina.

Family Applications Before (5)

Application Number Title Priority Date Filing Date
ES546595A Expired ES8703418A1 (es) 1984-09-01 1985-08-30 Un procedimiento para preparar derivados heterociclicos ni- trogenados
ES553614A Expired ES8801672A1 (es) 1984-09-01 1986-04-01 Un procedimiento para preparar derivados de alanil-prolina.
ES553612A Expired ES8801312A1 (es) 1984-09-01 1986-04-01 Un procedimiento para preparar derivados de alanil-prolina.
ES553611A Expired ES8801311A1 (es) 1984-09-01 1986-04-01 Un procedimiento para preparar derivados de alamil-prolina.
ES553610A Expired ES8801310A1 (es) 1984-09-01 1986-04-01 Un procedimiento para preparar derivados de alanil-protina.

Country Status (16)

Country Link
EP (1) EP0174162A3 (es)
JP (1) JPS6183198A (es)
KR (1) KR860002501A (es)
AU (1) AU581455B2 (es)
CS (1) CS621585A2 (es)
DD (1) DD236522A5 (es)
DK (1) DK396885A (es)
ES (6) ES8703418A1 (es)
FI (1) FI853336L (es)
GB (1) GB8422165D0 (es)
GR (1) GR852113B (es)
HU (1) HUT39190A (es)
MC (1) MC1695A1 (es)
PL (3) PL265522A1 (es)
PT (1) PT81055B (es)
ZA (1) ZA856672B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0237239A3 (en) * 1986-02-28 1988-08-17 The Wellcome Foundation Limited New compounds
FI870872A (fi) * 1986-02-28 1987-08-29 Wellcome Found Nya foereningar.
US5346887A (en) * 1987-10-06 1994-09-13 Abbott Laboratories Glaucoma treatment
US5036051A (en) * 1987-10-06 1991-07-30 Abbott Laboratories Glaucoma treatment
US4927807A (en) * 1987-10-06 1990-05-22 Abbott Laboratories Glaucoma treatment
US5187183A (en) * 1988-06-15 1993-02-16 Brigham & Women's Hospital S-nitroso derivatives of ACE inhibitors and the use thereof
US5356890A (en) * 1988-06-15 1994-10-18 Brigham And Women's Hospital S-nitroso derivatives of ace inhibitors and the use thereof
US5025001A (en) * 1988-06-15 1991-06-18 Brigham And Women's Hospital S-nitroso derivatives of ACE inhibitors and the use thereof
US5059589A (en) * 1988-09-08 1991-10-22 Abbott Laboratories Glaucoma treatment
US4916129A (en) * 1989-01-19 1990-04-10 E. I. Du Pont De Nemours And Company Combination β-blocking/angiotensin II blocking antihypertensives
US11229746B2 (en) 2006-06-22 2022-01-25 Excelsior Medical Corporation Antiseptic cap
US9259535B2 (en) 2006-06-22 2016-02-16 Excelsior Medical Corporation Antiseptic cap equipped syringe
US9078992B2 (en) 2008-10-27 2015-07-14 Pursuit Vascular, Inc. Medical device for applying antimicrobial to proximal end of catheter
US10166381B2 (en) 2011-05-23 2019-01-01 Excelsior Medical Corporation Antiseptic cap
WO2013009998A2 (en) 2011-07-12 2013-01-17 Pursuit Vascular, Inc. Device for delivery of antimicrobial agent into trans-dermal catheter
WO2015168677A1 (en) 2014-05-02 2015-11-05 Excelsior Medical Corporation Strip package for antiseptic cap
WO2016182822A1 (en) 2015-05-08 2016-11-17 Icu Medical, Inc. Medical connectors configured to receive emitters of therapeutic agents
EP4194043A1 (en) 2016-10-14 2023-06-14 ICU Medical, Inc. Sanitizing caps for medical connectors
WO2018204206A2 (en) 2017-05-01 2018-11-08 Icu Medical, Inc. Medical fluid connectors and methods for providing additives in medical fluid lines
US11541220B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Needleless connector with antimicrobial properties
US11541221B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Tubing set with antimicrobial properties
US11517732B2 (en) 2018-11-07 2022-12-06 Icu Medical, Inc. Syringe with antimicrobial properties
US11400195B2 (en) 2018-11-07 2022-08-02 Icu Medical, Inc. Peritoneal dialysis transfer set with antimicrobial properties
US11534595B2 (en) 2018-11-07 2022-12-27 Icu Medical, Inc. Device for delivering an antimicrobial composition into an infusion device
WO2020106985A1 (en) 2018-11-21 2020-05-28 Pursuit Vascular, Inc. Antimicrobial device comprising a cap with ring and insert
EP4255552A1 (en) 2020-12-07 2023-10-11 ICU Medical, Inc. Peritoneal dialysis caps, systems and methods

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3705907A (en) * 1970-02-19 1972-12-12 Sandoz Ltd 4-(2-hydroxy)-3-aminopropoxy)-indole derivatives
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
FR2503155A2 (fr) * 1980-10-02 1982-10-08 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
DE3177130D1 (de) * 1980-08-30 1990-01-11 Hoechst Ag Aminosaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung.
GR75019B (es) * 1980-09-17 1984-07-12 Univ Miami
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4462943A (en) * 1980-11-24 1984-07-31 E. R. Squibb & Sons, Inc. Carboxyalkyl amino acid derivatives of various substituted prolines
EP0080822A1 (en) * 1981-11-27 1983-06-08 Beecham Group Plc Anti-hypertensive prolinol-based peptides
IE55867B1 (en) * 1981-12-29 1991-02-14 Hoechst Ag New derivatives of bicyclic aminoacids,processes for their preparation,agents containing these compounds and their use,and new bicyclic aminoacids as intermediates and processes for their preparation
EP0088350B1 (en) * 1982-03-08 1985-02-20 Schering Corporation Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
EP0099709A3 (en) * 1982-07-19 1985-11-13 Imperial Chemical Industries Plc Amide derivatives

Also Published As

Publication number Publication date
GB8422165D0 (en) 1984-10-03
PT81055A (en) 1985-09-01
PL265523A1 (en) 1988-02-04
PL255192A1 (en) 1987-09-21
MC1695A1 (fr) 1986-07-18
KR860002501A (ko) 1986-04-26
EP0174162A2 (en) 1986-03-12
ES8801313A1 (es) 1988-01-01
CS621585A2 (en) 1989-08-14
JPS6183198A (ja) 1986-04-26
ES8801310A1 (es) 1988-01-01
DD236522A5 (de) 1986-06-11
PT81055B (en) 1987-07-02
ES546595A0 (es) 1987-02-16
ES8801312A1 (es) 1987-12-16
DK396885D0 (da) 1985-08-30
EP0174162A3 (en) 1988-07-27
AU4693285A (en) 1986-03-06
ES8801672A1 (es) 1988-02-16
FI853336L (fi) 1986-03-02
HUT39190A (en) 1986-08-28
ES553612A0 (es) 1987-12-16
ES8801311A1 (es) 1987-12-16
ES553610A0 (es) 1988-01-01
PL265522A1 (en) 1988-05-12
GR852113B (es) 1985-12-24
ES553614A0 (es) 1988-02-16
ES553611A0 (es) 1987-12-16
DK396885A (da) 1986-03-02
AU581455B2 (en) 1989-02-23
ZA856672B (en) 1987-05-27
ES8703418A1 (es) 1987-02-16
FI853336A0 (fi) 1985-08-30

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