[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

ES550943A0 - Un procedimiento para preparar una proteina de fusion derivada de la secuencia de aminoacidos de la preprorrelaxina humana. - Google Patents

Un procedimiento para preparar una proteina de fusion derivada de la secuencia de aminoacidos de la preprorrelaxina humana.

Info

Publication number
ES550943A0
ES550943A0 ES550943A ES550943A ES550943A0 ES 550943 A0 ES550943 A0 ES 550943A0 ES 550943 A ES550943 A ES 550943A ES 550943 A ES550943 A ES 550943A ES 550943 A0 ES550943 A0 ES 550943A0
Authority
ES
Spain
Prior art keywords
human
preprorellaxin
preparing
procedure
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES550943A
Other languages
English (en)
Other versions
ES8802394A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Florey Institute of Neuroscience and Mental Health
Original Assignee
Howard Florey Institute of Experimental Physiology and Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Howard Florey Institute of Experimental Physiology and Medicine filed Critical Howard Florey Institute of Experimental Physiology and Medicine
Publication of ES550943A0 publication Critical patent/ES550943A0/es
Publication of ES8802394A1 publication Critical patent/ES8802394A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/30—Signal or leader sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES550943A 1982-08-12 1986-01-16 Un procedimiento para preparar una proteina de fusion derivada de la secuencia de aminoacidos de la preprorrelaxina humana. Expired ES8802394A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPF535282 1982-08-12

Publications (2)

Publication Number Publication Date
ES550943A0 true ES550943A0 (es) 1988-05-16
ES8802394A1 ES8802394A1 (es) 1988-05-16

Family

ID=3769689

Family Applications (5)

Application Number Title Priority Date Filing Date
ES524885A Expired ES8603579A1 (es) 1982-08-12 1983-08-11 Un procedimiento para producir un vector de transferencia de adn.
ES540886A Expired ES8802160A1 (es) 1982-08-12 1985-03-01 Un procedimiento para aislar un gen de relaxina cromosomica de un ser humano o de otro primate o una especie afin
ES550943A Expired ES8802394A1 (es) 1982-08-12 1986-01-16 Un procedimiento para preparar una proteina de fusion derivada de la secuencia de aminoacidos de la preprorrelaxina humana.
ES557506A Expired ES8801671A1 (es) 1982-08-12 1987-04-15 Un procedimiento para preparar relaxina humana o sus analogos
ES557505A Expired ES8801676A1 (es) 1982-08-12 1987-04-15 Un procedimiento para preparar relaxina humana o sus analogos

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES524885A Expired ES8603579A1 (es) 1982-08-12 1983-08-11 Un procedimiento para producir un vector de transferencia de adn.
ES540886A Expired ES8802160A1 (es) 1982-08-12 1985-03-01 Un procedimiento para aislar un gen de relaxina cromosomica de un ser humano o de otro primate o una especie afin

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES557506A Expired ES8801671A1 (es) 1982-08-12 1987-04-15 Un procedimiento para preparar relaxina humana o sus analogos
ES557505A Expired ES8801676A1 (es) 1982-08-12 1987-04-15 Un procedimiento para preparar relaxina humana o sus analogos

Country Status (14)

Country Link
US (1) US4871670A (es)
EP (2) EP0101309B1 (es)
JP (3) JP2537477B2 (es)
KR (1) KR930003515B1 (es)
AT (1) ATE78042T1 (es)
CA (1) CA1340542C (es)
DE (1) DE3382117D1 (es)
DK (2) DK171827B1 (es)
ES (5) ES8603579A1 (es)
HU (1) HU197350B (es)
IE (1) IE58682B1 (es)
IL (1) IL69469A (es)
NZ (1) NZ205241A (es)
ZA (1) ZA835963B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5320953A (en) * 1982-08-12 1994-06-14 Howard Florey Institute Of Experimental Physiology And Medicine Process for synthesizing human H1-prorelaxin, H1-relaxin and fusion proteins thereof
IL70414A (en) * 1982-12-13 1991-06-10 Florey Howard Inst Polypeptide having human h2-relaxin activity,double-stranded dna fragments coding therefor,vectors containing the dna fragments and methods for preparing the polypeptide,dna fragments and vectors
US5023321A (en) * 1982-12-13 1991-06-11 Howard Florey Institute Of Experimental Physiology & Medicine Molecular cloning and characterization of a further gene sequence coding for human relaxin
US4835251A (en) * 1986-06-23 1989-05-30 Genetech, Inc. Method of chain combination
EP0407401B1 (en) * 1988-02-26 1993-04-21 Genentech, Inc. Human relaxin formulation
WO1990013659A1 (en) * 1989-05-04 1990-11-15 Genentech, Inc. Processes and compositions for the isolation of human relaxin
US5089419A (en) * 1989-08-07 1992-02-18 International Canine Genetics Detection of pregnancy by identification of the c peptide of relaxin in the urine of animals
US5166191A (en) * 1991-08-19 1992-11-24 Genentech, Inc. Use of relaxin in cardiovascular therapy
US5478807A (en) * 1991-08-19 1995-12-26 Genentech, Inc. Use of relaxin in the treatment of bradycardia
US6348327B1 (en) * 1991-12-06 2002-02-19 Genentech, Inc. Non-endocrine animal host cells capable of expressing variant proinsulin and processing the same to form active, mature insulin and methods of culturing such cells
JP3954091B2 (ja) * 1993-06-21 2007-08-08 ジェネンテック・インコーポレーテッド リラキシンの製造方法
US5911997A (en) * 1995-06-07 1999-06-15 Connetics Corporation Relaxin-like factor and methods and uses thereof
WO2002085308A2 (en) * 2001-04-24 2002-10-31 Epigenesis Pharmaceuticals, Inc. Antisense and anti-inflammatory based compositions to treat respiratory disorders
US20030088884A1 (en) * 2001-08-17 2003-05-08 Hsu Sheau Yu Mammalian relaxin receptors
AU2003903124A0 (en) * 2003-06-20 2003-07-10 Mark Del Borgo Analogues of heteromeric proteins
US7553813B2 (en) * 2004-04-30 2009-06-30 Corthera, Inc. Methods and compositions for control of fetal growth via modulation of relaxin
US20060052304A1 (en) * 2004-09-02 2006-03-09 Bas Medical, Inc. Method for remodeling bone and related sutures
US8389475B2 (en) 2009-08-10 2013-03-05 The Board Of Trustees Of The Leland Stanford Junior University Relaxin analogs
US8735539B2 (en) 2010-08-17 2014-05-27 Ambrx, Inc. Relaxin polypeptides comprising non-naturally encoded amino acids
CA2821711C (en) 2010-12-15 2017-10-10 Baxter International Inc. Eluate collection using conductivity gradient
EP2630964A1 (en) 2012-02-22 2013-08-28 Immundiagnostik AG Method and medicament for treating patients in risk of prediabetes and type-2 diabetes
EP3068891A1 (en) 2013-11-13 2016-09-21 Aequus Biopharma Inc. Engineered glycoproteins and uses thereof
EP2946788A1 (en) 2014-05-23 2015-11-25 Immundiagnostik AG Method and composition for treating heart failure with preserved ejection fraction
KR20230074598A (ko) 2016-05-18 2023-05-30 모더나티엑스, 인크. 릴랙신을 인코딩하는 폴리뉴클레오타이드

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267101A (en) * 1980-02-01 1981-05-12 Serono Laboratories Inc. Process for obtaining human relaxin from fetal membranes
IE55479B1 (en) * 1982-02-12 1990-09-26 Florey Howard Inst Molecular cloning and characterization of the gene sequence coding for porcine relaxin
IL70414A (en) * 1982-12-13 1991-06-10 Florey Howard Inst Polypeptide having human h2-relaxin activity,double-stranded dna fragments coding therefor,vectors containing the dna fragments and methods for preparing the polypeptide,dna fragments and vectors

Also Published As

Publication number Publication date
JPH07215998A (ja) 1995-08-15
DK171827B1 (da) 1997-06-23
CA1340542C (en) 1999-05-18
EP0101309A3 (en) 1984-12-27
DE3382117D1 (de) 1991-02-21
DK171683B1 (da) 1997-03-10
ZA835963B (en) 1984-04-25
US4871670A (en) 1989-10-03
ES524885A0 (es) 1985-12-16
ES8801671A1 (es) 1988-02-16
ATE78042T1 (de) 1992-07-15
KR930003515B1 (ko) 1993-05-01
DK366483D0 (da) 1983-08-11
EP0287820B1 (en) 1992-07-08
JP2670001B2 (ja) 1997-10-29
EP0287820A1 (en) 1988-10-26
ES557506A0 (es) 1988-02-16
EP0101309A2 (en) 1984-02-22
ES8802160A1 (es) 1988-04-01
DK156592D0 (da) 1992-12-28
IL69469A (en) 1991-06-10
IE831909L (en) 1984-02-12
DK156592A (da) 1992-12-28
JPS5985292A (ja) 1984-05-17
HU197350B (en) 1989-03-28
JP2537477B2 (ja) 1996-09-25
ES8802394A1 (es) 1988-05-16
NZ205241A (en) 1991-01-29
IE58682B1 (en) 1993-11-03
ES8603579A1 (es) 1985-12-16
JPH0690780A (ja) 1994-04-05
JP2892596B2 (ja) 1999-05-17
IL69469A0 (en) 1983-11-30
DK366483A (da) 1984-02-13
EP0101309B1 (en) 1991-01-16
KR840005739A (ko) 1984-11-16
ES540886A0 (es) 1988-04-01
ES8801676A1 (es) 1988-02-16
ES557505A0 (es) 1988-02-16

Similar Documents

Publication Publication Date Title
ES550943A0 (es) Un procedimiento para preparar una proteina de fusion derivada de la secuencia de aminoacidos de la preprorrelaxina humana.
DK152082A (da) Anvendelse af radiomaerket peptid afledt af tvaerbundet fibrin til at lokalisere blodpropper in vivo
ES552093A0 (es) Un procedimiento para sintetizar una secuencia de aminoacidos que contienen la totalidad o parte de la secuencia de aminoacidos de la preprorrelaxina -h2 humana.
ATE316099T1 (de) Immunotherapeutische methoden mit verwendung von wt-1 and gata-1 epitopen
ES549817A0 (es) Un metodo para producir proteina tensioactiva alveolar
DK532284A (da) Fremgangsmaade til bestemmelse af antigenaktive aminosyresekvenser
AR058982A1 (es) Vector de expresion de la proteina bicunina y metodo para producir dicha proteina
PT89961A (pt) Processo para a preparacao de n-carboxianidridos de aminoacidos protegidos por uretano
ES533924A0 (es) Procedimiento para preparar proteina de uroquinasa humana bioactiva
ES2140390T3 (es) Metodos para la trans-desestabilizacion de proteinas in vivo.
ES548617A0 (es) Procedimiento para disociar peptidos y proteinas en el enla-ce metionilo
DK611386A (da) Recombinant humant fsh, fremgangsmaade til fremstilling deraf og vektorer og celler til anvendelse ved fremgangsmaaden
MX167236B (es) Peptidos sinteticos de timosina -1 y metodo para su obtencion
NO20005081D0 (no) Et polypeptid inneholdende aminosyren fra et N-terminalt kolinbindende protein A-truncat, vaksine avledet derfra og anvendelser derav
DE69012989D1 (de) Peptiden von retinblastoma gen produkten und antikoerper dagegen.
ES2158235T3 (es) Peptidos antigenicos con substituciones de glicina.
DE3485883D1 (de) Rekombinante materialien und verfahren zur herstellung von menschliche konnektive gewebe aktivierende peptide iii und deren analoge.
ATE79651T1 (de) Rekombinante materialien und verfahren zur herstellung von menschliche konnektive gewebe aktivierende peptide iii und deren analoge.
FI961398A (fi) Menetelmä terapeuttisesti käyttökelpoisen peptidin valmistamiseksi