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ES538867A0 - Un derivado de 5-fluor-3-oxa-prostaciclina - Google Patents

Un derivado de 5-fluor-3-oxa-prostaciclina

Info

Publication number
ES538867A0
ES538867A0 ES538867A ES538867A ES538867A0 ES 538867 A0 ES538867 A0 ES 538867A0 ES 538867 A ES538867 A ES 538867A ES 538867 A ES538867 A ES 538867A ES 538867 A0 ES538867 A0 ES 538867A0
Authority
ES
Spain
Prior art keywords
prostacicline
oxa
fluorine
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES538867A
Other languages
English (en)
Other versions
ES8604508A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of ES538867A0 publication Critical patent/ES538867A0/es
Publication of ES8604508A1 publication Critical patent/ES8604508A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES538867A 1983-12-23 1984-12-20 Un derivado de 5-fluor-3-oxa-prostaciclina Expired ES8604508A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/565,250 US4579958A (en) 1983-12-23 1983-12-23 5-fluoro-3-oxa-6,7-didehydro-PGI1 compounds

Publications (2)

Publication Number Publication Date
ES538867A0 true ES538867A0 (es) 1986-02-01
ES8604508A1 ES8604508A1 (es) 1986-02-01

Family

ID=24257800

Family Applications (1)

Application Number Title Priority Date Filing Date
ES538867A Expired ES8604508A1 (es) 1983-12-23 1984-12-20 Un derivado de 5-fluor-3-oxa-prostaciclina

Country Status (6)

Country Link
US (1) US4579958A (es)
EP (1) EP0148010A3 (es)
JP (1) JPS60222475A (es)
AU (1) AU3696184A (es)
ES (1) ES8604508A1 (es)
ZA (1) ZA849944B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4611065A (en) * 1985-01-25 1986-09-09 G. D. Searle & Co. Method for preparing 5-fluoroprostacyclins
DE3526362A1 (de) * 1985-07-19 1987-01-22 Schering Ag Prostacycline, ihre analoga oder prostaglandine und thromboxanantagonisten zur behandlung von thrombotischen und thromboembolischen krankheitsbildern
JP2716986B2 (ja) 1987-07-17 1998-02-18 シエーリング アクチエンゲゼルシヤフト ９‐ハロゲン‐（ｚ）‐プロスタグランジン誘導体、その製法及び薬剤としてのその使用
AU634871B2 (en) * 1990-03-20 1993-03-04 Banyu Pharmaceutical Co., Ltd. Substituted amine derivatives having anti-hyperlipemia activity
EP1220849B1 (en) 1999-10-15 2004-05-19 Sucampo AG Bicyclic compounds composition and method for stabilizing the same
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923861A (en) * 1969-07-29 1975-12-02 Upjohn Co 3-Oxa prostaglandin F{331 -type compounds
US4324730A (en) * 1979-10-10 1982-04-13 The University Of Chicago Certain fluorine substituted PGI2 compounds
WO1981001002A1 (en) * 1979-10-10 1981-04-16 Univ Chicago Fluoro-substituted prostaglandins and prostacyclins
ES511067A0 (es) * 1981-04-02 1983-06-16 Searle & Co Procedimiento para preparar un derivado de prostaglandina.

Also Published As

Publication number Publication date
EP0148010A3 (en) 1985-12-27
AU3696184A (en) 1985-07-04
US4579958A (en) 1986-04-01
JPS60222475A (ja) 1985-11-07
ES8604508A1 (es) 1986-02-01
EP0148010A2 (en) 1985-07-10
ZA849944B (en) 1986-02-26

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