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ES536502A0 - Procedimiento para la fabricacion de acido 7beta-(carboxialquenoilamino)-3-cefem-4-carboxilico - Google Patents

Procedimiento para la fabricacion de acido 7beta-(carboxialquenoilamino)-3-cefem-4-carboxilico

Info

Publication number
ES536502A0
ES536502A0 ES536502A ES536502A ES536502A0 ES 536502 A0 ES536502 A0 ES 536502A0 ES 536502 A ES536502 A ES 536502A ES 536502 A ES536502 A ES 536502A ES 536502 A0 ES536502 A0 ES 536502A0
Authority
ES
Spain
Prior art keywords
carboxialquenoilamino
carboxilico
7beta
cefem
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES536502A
Other languages
English (en)
Other versions
ES8604602A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP58186601A external-priority patent/JPS6078987A/ja
Priority claimed from JP59018563A external-priority patent/JPS60163884A/ja
Priority claimed from JP59100890A external-priority patent/JPH0780892B2/ja
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of ES536502A0 publication Critical patent/ES536502A0/es
Publication of ES8604602A1 publication Critical patent/ES8604602A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65613—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES536502A 1983-10-04 1984-10-04 Procedimiento para la fabricacion de acido 7beta-(carboxialquenoilamino)-3-cefem-4-carboxilico Expired ES8604602A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP58186601A JPS6078987A (ja) 1983-10-04 1983-10-04 アクリルアミドセフアロスポリン類
JP59018563A JPS60163884A (ja) 1984-02-03 1984-02-03 カルボキシアルケンアミドセフアロスポリン
JP59100890A JPH0780892B2 (ja) 1984-05-18 1984-05-18 カルボキシアルケンアミドセフアロスポリン

Publications (2)

Publication Number Publication Date
ES536502A0 true ES536502A0 (es) 1986-02-01
ES8604602A1 ES8604602A1 (es) 1986-02-01

Family

ID=27282263

Family Applications (3)

Application Number Title Priority Date Filing Date
ES536502A Expired ES8604602A1 (es) 1983-10-04 1984-10-04 Procedimiento para la fabricacion de acido 7beta-(carboxialquenoilamino)-3-cefem-4-carboxilico
ES547300A Expired ES8700222A1 (es) 1983-10-04 1985-08-29 Nuevo procedimiento para la fabricacion de acido 7-beta- (carboxialquenoilamino)-3-cefem-4-carboxilico
ES547301A Expired ES8605278A1 (es) 1983-10-04 1985-08-29 Procedimiento perfeccionado para la fabricacion de acido 7- beta-(carboxialquenoilamino)-3-cefem-4-carboxilico

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES547300A Expired ES8700222A1 (es) 1983-10-04 1985-08-29 Nuevo procedimiento para la fabricacion de acido 7-beta- (carboxialquenoilamino)-3-cefem-4-carboxilico
ES547301A Expired ES8605278A1 (es) 1983-10-04 1985-08-29 Procedimiento perfeccionado para la fabricacion de acido 7- beta-(carboxialquenoilamino)-3-cefem-4-carboxilico

Country Status (22)

Country Link
US (3) US4634697A (es)
EP (1) EP0136721B1 (es)
KR (2) KR880002376B1 (es)
AR (1) AR242392A1 (es)
AT (1) ATE99311T1 (es)
AU (2) AU575854B2 (es)
CA (2) CA1238910A (es)
DE (2) DE3486259T2 (es)
DK (1) DK171043B1 (es)
ES (3) ES8604602A1 (es)
FI (1) FI82057C (es)
GB (3) GB2154580B (es)
GR (1) GR80544B (es)
HU (1) HU193298B (es)
IE (1) IE57744B1 (es)
IL (3) IL84653A (es)
MX (1) MX174328B (es)
NL (1) NL940013I2 (es)
NO (2) NO173238C (es)
NZ (2) NZ209634A (es)
PH (2) PH20223A (es)
PT (1) PT79287A (es)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
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AU575854B2 (en) * 1983-10-04 1988-08-11 Shionogi & Co., Ltd. 7beta-(carboxyalkenamido) cephalosporins
JP2501785B2 (ja) * 1984-07-09 1996-05-29 明治製菓株式会社 新規セフアロスポリン系化合物
JPS6124580A (ja) * 1984-07-12 1986-02-03 Shionogi & Co Ltd アミノチアゾリルグルタル酸誘導体の製造方法
JPS6153272A (ja) * 1984-08-24 1986-03-17 Shionogi & Co Ltd グルタル酸誘導体の製法
AU580855B2 (en) * 1985-03-29 1989-02-02 Shionogi & Co., Ltd. Alkeneamidocephalosporin esters
IL78634A0 (en) 1985-04-30 1986-08-31 Lilly Co Eli 7-substituted bicyclic pyrazolidinones
US4731362A (en) * 1985-08-05 1988-03-15 Shionogi & Co., Ltd. Alkylcarbamoyloxymethylcephem compounds
US5017380A (en) * 1986-07-02 1991-05-21 Shionogi & Co., Ltd. Gelatin hard capsule containing crystalline hydrate of oral cephalosporin
AT396652B (de) * 1986-07-02 1993-11-25 Shionogi & Co Verfahren zur herstellung von hartgelatinekapsel-zusammensetzungen
DE3745094B4 (de) * 1986-07-02 2004-12-30 Shionogi & Co., Ltd. Ein kristallines Hydrat der 7ß-[(Z)-2-(2-Aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-carbonsäure enthaltende Hartgelatinekapsel-Zusammensetzung
NZ220764A (en) * 1986-07-02 1989-09-27 Shionogi & Co Crystalline form of 7beta((z)-2-(2-aminothiazol-4-yl)-4- carboxybut-2-enoylamino)-3-cephem-4-carboxylic acid and pharmaceutical compositions
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US4820832A (en) * 1988-03-23 1989-04-11 Eli Lilly And Company Process for preparing 3-unsubstituted cephalosporins and 1-carba(dethia)cephalosporins
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US5336768A (en) * 1988-05-24 1994-08-09 Hoffmann-La Roche Inc. Antibacterial cephalosporin compounds
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JPH101482A (ja) * 1996-06-13 1998-01-06 Otsuka Chem Co Ltd ３−ノルセフェム化合物の製造法
US6544555B2 (en) * 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
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JP5249344B2 (ja) * 2007-11-16 2013-07-31 メルク・シャープ・アンド・ドーム・コーポレーション ヘテロ環の３位が置換されたインドール誘導体およびその使用
CN102159579B (zh) * 2008-06-13 2015-03-25 默沙东公司 三环吲哚衍生物及其使用方法
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JP5731976B2 (ja) 2008-08-20 2015-06-10 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． 置換ピリジン誘導体および置換ピリミジン誘導体ならびにそれらのウイルス感染の治療における使用
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US20130156731A1 (en) 2009-12-22 2013-06-20 Kevin X. Chen Fused tricyclic compounds and methods of use thereof for the treatment of viral diseas
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EP2598149A4 (en) 2010-07-26 2014-09-10 Merck Sharp & Dohme SUBSTITUTED BIPHENYLENE COMPOUNDS AND METHOD FOR USE THEREOF FOR THE TREATMENT OF VIRUS DISEASES
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Also Published As

Publication number Publication date
DK474584D0 (da) 1984-10-03
EP0136721B1 (en) 1993-12-29
GB2198727A (en) 1988-06-22
NO843956L (no) 1985-04-09
NZ209634A (en) 1988-07-28
NL940013I2 (nl) 1999-06-01
GB2190914B (en) 1988-08-17
IL73159A (en) 1990-08-31
GB2154580A (en) 1985-09-11
DK474584A (da) 1985-04-05
KR850002989A (ko) 1985-05-28
GB8700123D0 (en) 1987-02-11
ES8605278A1 (es) 1986-03-16
NO173238B (no) 1993-08-09
IE57744B1 (en) 1993-03-24
AU601842B2 (en) 1990-09-20
ES547301A0 (es) 1986-03-16
NL940013I1 (nl) 1994-08-16
US4634697A (en) 1987-01-06
FI843871A0 (fi) 1984-10-02
AU3330084A (en) 1985-05-09
AU575854B2 (en) 1988-08-11
FI82057C (fi) 1991-01-10
ES8700222A1 (es) 1986-11-16
ATE99311T1 (de) 1994-01-15
ES547300A0 (es) 1986-11-16
DE3486259T2 (de) 1994-07-21
CA1272713A (en) 1990-08-14
GR80544B (en) 1985-02-05
KR880002376B1 (ko) 1988-11-03
PT79287A (en) 1984-11-01
GB2154580B (en) 1988-08-17
FI843871L (fi) 1985-04-05
IL73159A0 (en) 1985-01-31
IE842524L (en) 1985-04-04
MX174328B (es) 1994-05-09
KR880002684B1 (ko) 1988-12-20
NO176567B (no) 1995-01-16
US4748170A (en) 1988-05-31
NO176567C (no) 1995-04-26
NO173238C (no) 1993-11-17
AU1619488A (en) 1988-08-11
NZ218741A (en) 1988-07-28
PH20223A (en) 1986-10-23
DE3486259D1 (de) 1994-02-10
DE136721T1 (de) 1985-08-29
US4912224A (en) 1990-03-27
PH21766A (en) 1988-02-18
IL84653A0 (en) 1988-04-29
HU193298B (en) 1987-09-28
ES8604602A1 (es) 1986-02-01
GB8726623D0 (en) 1987-12-16
EP0136721A2 (en) 1985-04-10
CA1272713C (es) 1990-08-14
GB2190914A (en) 1987-12-02
GB2198727B (en) 1988-11-16
AR242392A1 (es) 1993-03-31
IL84653A (en) 1990-08-31
CA1238910A (en) 1988-07-05
DK171043B1 (da) 1996-04-29
GB8424923D0 (en) 1984-11-07
FI82057B (fi) 1990-09-28
HUT36129A (en) 1985-08-28
EP0136721A3 (en) 1986-01-22
NO853806L (no) 1985-04-09

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