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ES525239A0 - Un procedimiento para la preparacion de derivados del acido ascorbico - Google Patents

Un procedimiento para la preparacion de derivados del acido ascorbico

Info

Publication number
ES525239A0
ES525239A0 ES525239A ES525239A ES525239A0 ES 525239 A0 ES525239 A0 ES 525239A0 ES 525239 A ES525239 A ES 525239A ES 525239 A ES525239 A ES 525239A ES 525239 A0 ES525239 A0 ES 525239A0
Authority
ES
Spain
Prior art keywords
procedure
preparation
ascorbic acid
acid derivatives
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES525239A
Other languages
English (en)
Other versions
ES8502698A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES525239A0 publication Critical patent/ES525239A0/es
Publication of ES8502698A1 publication Critical patent/ES8502698A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62Three oxygen atoms, e.g. ascorbic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES525239A 1982-01-15 1983-08-30 Un procedimiento para la preparacion de derivados del acido ascorbico Expired ES8502698A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33934482A 1982-01-15 1982-01-15

Publications (2)

Publication Number Publication Date
ES525239A0 true ES525239A0 (es) 1985-01-16
ES8502698A1 ES8502698A1 (es) 1985-01-16

Family

ID=23328588

Family Applications (2)

Application Number Title Priority Date Filing Date
ES518968A Expired ES8403118A1 (es) 1982-01-15 1983-01-13 Un procedimiento para la preparacion de derivados del acido ascorbico.
ES525239A Expired ES8502698A1 (es) 1982-01-15 1983-08-30 Un procedimiento para la preparacion de derivados del acido ascorbico

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES518968A Expired ES8403118A1 (es) 1982-01-15 1983-01-13 Un procedimiento para la preparacion de derivados del acido ascorbico.

Country Status (16)

Country Link
EP (1) EP0086554A1 (es)
JP (1) JPS58131978A (es)
KR (1) KR840003247A (es)
AU (1) AU1035183A (es)
CA (1) CA1181078A (es)
DD (1) DD209455A5 (es)
DK (1) DK14283A (es)
ES (2) ES8403118A1 (es)
FI (1) FI830078A7 (es)
GB (1) GB2114571A (es)
GR (1) GR77897B (es)
IL (1) IL67646A0 (es)
PL (1) PL240125A1 (es)
PT (1) PT76083B (es)
RO (1) RO86439B (es)
ZA (1) ZA83173B (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4552895A (en) * 1983-03-14 1985-11-12 Eli Lilly And Company Furo[3,2-b]furan-2-(3H)-ones
JPS6058973A (ja) * 1983-09-13 1985-04-05 Mitsubishi Yuka Yakuhin Kk γ−プチロラクトン誘導体及びそれを有効成分とする免疫調節剤
WO1986007592A1 (en) * 1985-06-18 1986-12-31 Takeda Chemical Industries, Ltd. Ascorbic acid derivatives, process for their preparation, and preparations containing same
WO1986006720A1 (en) * 1985-05-17 1986-11-20 Takeda Chemical Industries, Ltd. Ascorbic acid derivatives, production thereof, and pharmaceutical preparation therefrom
JPS60130582A (ja) * 1983-12-19 1985-07-12 Takeda Chem Ind Ltd 食品用酸化防止剤,アスコルビン酸誘導体およびその製造法
JPS60139619A (ja) * 1983-12-27 1985-07-24 Mutsuyuki Kochi O−ベンジリデン−アスコルビン酸又はその塩よりなる抗腫瘍剤
JP2515556B2 (ja) * 1986-08-29 1996-07-10 武田薬品工業株式会社 ヒドロキシブテノライド誘導体およびその製造法
JPH0730066B2 (ja) * 1988-03-09 1995-04-05 株式会社日本ハイポックス アスコルビン酸誘導体及びアスコルビン酸誘導体からなる抗酸化剤
JP2752080B2 (ja) * 1988-03-09 1998-05-18 株式会社日本ハイポックス アスコルビン酸誘導体及びその製造方法並びにアスコルビン酸誘導体からなる抗酸化剤
ES2099064T3 (es) 1988-09-01 1997-05-16 Takeda Chemical Industries Ltd Derivados de fumagillol.
DE69024193T2 (de) * 1989-09-11 1996-05-30 Nippon Hypox Lab Inc Ascorbinsäure-derivate
US5095126A (en) * 1990-01-12 1992-03-10 Ohio State University Research Foundation Efficient synthesis for optically pure stereogenically labile 4-substituted-2-hydroxytetronic acids
JP3206602B2 (ja) * 1990-03-07 2001-09-10 エフ・ホフマン―ラ ロシユ アーゲー アスコルビン酸の誘導体の製造方法
US5270336A (en) * 1990-03-16 1993-12-14 Merrell Dow Pharmaceuticals Inc. Ascorbic acid derivatives
EP0446539A1 (en) * 1990-03-16 1991-09-18 Merrell Dow Pharmaceuticals Inc. Novel ascorbic acid derivatives
JPH0429989A (ja) * 1990-05-24 1992-01-31 Nisshin Flour Milling Co Ltd L―アスコルビン酸誘導体の製造法
GB9026114D0 (en) * 1990-11-30 1991-01-16 Norsk Hydro As New compounds
GB9201274D0 (en) * 1992-01-21 1992-03-11 Norsk Hydro As New compounds
GB9201275D0 (en) * 1992-01-21 1992-03-11 Norsk Hydro As New compounds
TW325997B (en) * 1993-02-02 1998-02-01 Senju Pharma Co Pharmaceutical composition for preventing and treating retinal diseases
RU2126398C1 (ru) * 1993-02-05 1999-02-20 Плива, Фармацеутска, Кемийска, Прехрамбена и Козметичка Индустрия Дионичко Друштво Загреб Производные аминоаскорбиновой кислоты, способы их получения и производные галоидаскорбиновой кислоты
US5629327A (en) 1993-03-01 1997-05-13 Childrens Hospital Medical Center Corp. Methods and compositions for inhibition of angiogenesis
US6114355A (en) * 1993-03-01 2000-09-05 D'amato; Robert Methods and compositions for inhibition of angiogenesis
US6228879B1 (en) 1997-10-16 2001-05-08 The Children's Medical Center Methods and compositions for inhibition of angiogenesis
US5504074A (en) 1993-08-06 1996-04-02 Children's Medical Center Corporation Estrogenic compounds as anti-angiogenic agents
US6908910B2 (en) 1993-08-06 2005-06-21 The Children's Medical Center Corporation Estrogenic compounds as anti-mitotic agents
DE69738935D1 (de) 1996-11-05 2008-10-02 Childrens Medical Center Zusammensetzungen enthaltend Thalidomide und Dexamethason für die Behandlung von Krebs
EP0875246A1 (en) * 1997-04-04 1998-11-04 Showa Denko Kabushiki Kaisha Pharmaceutical preparation of ascorbic acid derivatives for medical treatment of cancer
WO1999050258A1 (en) * 1998-03-27 1999-10-07 Lg Chemical Ltd. Polyethoxylated ascorbic acid derivatives as a novel antioxidant and process for preparing thereof
US6673828B1 (en) 1998-05-11 2004-01-06 Children's Medical Center Corporation Analogs of 2-Phthalimidinoglutaric acid
US7087592B1 (en) 1999-08-23 2006-08-08 Entre Med, Inc. Compositions comprising purified 2-methoxyestradiol and methods of producing same
WO2001056566A1 (fr) * 2000-02-01 2001-08-09 Mutsuyuki Kochi Compositions inhibitrices de neovascularisation et procede correspondant
SK13902002A3 (sk) * 2000-03-31 2003-05-02 Angiogene Pharmaceuticals Ltd. Liečivo obsahujúce činidlá poškodzujúce cievy, kit, ktorý toto liečivo obsahuje, a použitie liečiva
WO2003010173A1 (en) * 2001-07-26 2003-02-06 Tagra Biotechnologies Ltd. Stabilized derivatives of ascorbic acid -3-phosphate
US7977379B2 (en) 2002-05-15 2011-07-12 Bhn Co., Ltd. Method for angiogenesis inhibition or immunostimulation
EP1939192A1 (en) * 2006-12-28 2008-07-02 Neuropharma S.A. Cyclopentanone derivatives, method of synthesis and uses thereof
FR2955493B1 (fr) * 2010-01-28 2012-02-24 Oreal Utilisation de derives d'acide ascorbique en coloration des fibres keratiniques humaines, composition les comprenant, procede de coloration et dispositif
JP5602456B2 (ja) * 2010-02-24 2014-10-08 日本精化株式会社 アスコルビン酸誘導体
US9550744B2 (en) * 2013-09-25 2017-01-24 University Of Florida Research Foundation, Inc. Vitamin C prodrugs and uses thereof
US10105407B2 (en) * 2015-06-09 2018-10-23 John P. Crow, JR. Methods of extraction of nitrosylated or nitrated derivatives of ascorbic acid from myriciaria dubia and methods of synthesis thereof
EP3383429B1 (en) 2015-11-30 2020-10-14 INSERM - Institut National de la Santé et de la Recherche Médicale Nmdar antagonists for the treatment of tumor angiogenesis

Also Published As

Publication number Publication date
DK14283D0 (da) 1983-01-14
FI830078L (fi) 1983-07-16
FI830078A0 (fi) 1983-01-10
PT76083B (en) 1986-01-09
EP0086554A1 (en) 1983-08-24
ES518968A0 (es) 1984-03-01
ES8403118A1 (es) 1984-03-01
PT76083A (en) 1983-02-01
GB2114571A (en) 1983-08-24
CA1181078A (en) 1985-01-15
GR77897B (es) 1984-09-25
PL240125A1 (en) 1984-04-24
DK14283A (da) 1983-07-16
ES8502698A1 (es) 1985-01-16
JPS58131978A (ja) 1983-08-06
RO86439A (ro) 1985-03-15
DD209455A5 (de) 1984-05-09
RO86439B (ro) 1985-03-31
ZA83173B (en) 1984-08-29
KR840003247A (ko) 1984-08-20
IL67646A0 (en) 1983-05-15
AU1035183A (en) 1983-07-21
GB8300907D0 (en) 1983-02-16
FI830078A7 (fi) 1983-07-16

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