ES510087A0 - Procedimiento para la preparacion de nuevos compuestos de aorilimidazol-2-ona. - Google Patents
Procedimiento para la preparacion de nuevos compuestos de aorilimidazol-2-ona.Info
- Publication number
- ES510087A0 ES510087A0 ES510087A ES510087A ES510087A0 ES 510087 A0 ES510087 A0 ES 510087A0 ES 510087 A ES510087 A ES 510087A ES 510087 A ES510087 A ES 510087A ES 510087 A0 ES510087 A0 ES 510087A0
- Authority
- ES
- Spain
- Prior art keywords
- aorilimidazole
- procedure
- preparation
- new
- ona
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Luminescent Compositions (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24088981A | 1981-03-05 | 1981-03-05 | |
| US06/314,312 US4405628A (en) | 1981-03-05 | 1981-10-23 | 4-Pyridylimidazolones and method of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES510087A0 true ES510087A0 (es) | 1983-04-16 |
| ES8305352A1 ES8305352A1 (es) | 1983-04-16 |
Family
ID=26933806
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES510087A Expired ES8305352A1 (es) | 1981-03-05 | 1982-03-03 | Procedimiento para la preparacion de nuevos compuestos de aorilimidazol-2-ona. |
| ES519254A Granted ES519254A0 (es) | 1981-03-05 | 1983-01-25 | Procedimiento para la preparacion de nuevos compuestos de aroilimidazol-2-ona. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES519254A Granted ES519254A0 (es) | 1981-03-05 | 1983-01-25 | Procedimiento para la preparacion de nuevos compuestos de aroilimidazol-2-ona. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4405628A (es) |
| EP (1) | EP0059948B1 (es) |
| KR (1) | KR890000765B1 (es) |
| AT (1) | ATE16489T1 (es) |
| AU (1) | AU557590B2 (es) |
| CA (1) | CA1190550A (es) |
| DE (1) | DE3267352D1 (es) |
| DK (1) | DK168627B1 (es) |
| ES (2) | ES8305352A1 (es) |
| GB (1) | GB2096600B (es) |
| GR (1) | GR76518B (es) |
| HK (1) | HK61686A (es) |
| IE (1) | IE52387B1 (es) |
| IL (1) | IL65137A (es) |
| MY (1) | MY8600700A (es) |
| NO (1) | NO157175C (es) |
| NZ (1) | NZ199885A (es) |
| PH (1) | PH18345A (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4367236A (en) * | 1981-11-04 | 1983-01-04 | Merrell Dow Pharmaceuticals Inc. | Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives |
| US4552880A (en) * | 1983-02-15 | 1985-11-12 | Merrell Dow Pharmaceuticals Inc. | Aroylimidazolones |
| US4532250A (en) * | 1983-11-23 | 1985-07-30 | American Hospital Supply Corporation | 5-Heteroarylimidazol-2-ones having cardiotonic activity |
| US4556665A (en) * | 1984-07-09 | 1985-12-03 | Schering A.G. | Cardiotonic 1,3-dihydro-4-[[(imidazol-1-yl)aryl]carbonyl]imidazol-2-ones |
| US4803278A (en) * | 1984-07-30 | 1989-02-07 | Merrell Dow Pharmaceuticals, Inc. | Preparation of 1,3-dihydro-4-pyridoyl-2H-imidazol-2-ones |
| IL75902A (en) * | 1984-07-30 | 1988-10-31 | Merrell Dow Pharma | Preparation of 1,3-dihydro-4-pyridoyl-2h-imidazol-2-ones |
| ZA881807B (en) * | 1987-03-20 | 1988-09-05 | Merrell Dow Pharmaceuticals Inc. | Method for reducing reperfusion injury with imidazol-2-thiones |
| US4999365A (en) * | 1987-03-20 | 1991-03-12 | Merrell Dow Pharmaceuticals Inc. | Method of reducing reperfusion injury with imidazol-2-thiones |
| ZA887662B (en) * | 1987-10-19 | 1989-06-28 | Merrell Dow Pharma | Method for reducing reperfusion injury with imidazol-2-thione-carboxamides |
| JPH05507933A (ja) * | 1990-06-29 | 1993-11-11 | ジ・アップジョン・カンパニー | Ｃｎｓおよび抗高血圧活性を有する置換１―（アルコキシフェニル）ピペラジン類 |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| EA020466B1 (ru) | 2007-06-04 | 2014-11-28 | Синерджи Фармасьютикалз Инк. | Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний |
| CA2930674A1 (en) | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| JP2011528375A (ja) | 2008-07-16 | 2011-11-17 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| WO2012118972A2 (en) | 2011-03-01 | 2012-09-07 | Synegy Pharmaceuticals Inc. | Process of preparing guanylate cyclase c agonists |
| WO2014131024A2 (en) | 2013-02-25 | 2014-08-28 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| JP2016514670A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト |
| AU2014235215A1 (en) | 2013-03-15 | 2015-10-01 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| US10011637B2 (en) | 2013-06-05 | 2018-07-03 | Synergy Pharmaceuticals, Inc. | Ultra-pure agonists of guanylate cyclase C, method of making and using same |
| US20160184387A1 (en) | 2013-08-09 | 2016-06-30 | Dominique Charmot | Compounds and methods for inhibiting phosphate transport |
| JP2022533251A (ja) | 2019-05-21 | 2022-07-21 | アルデリックス， インコーポレイテッド | 患者において血清リン酸塩を低下させるための組み合わせ |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2441933A (en) * | 1945-07-30 | 1948-05-18 | Hoffmann La Roche | Substituted imidazolones and process of making them |
| US3538104A (en) * | 1969-02-28 | 1970-11-03 | Geigy Chem Corp | Pyridyl-2-imidazolones |
| ZA803332B (en) * | 1979-06-18 | 1981-01-28 | Richardson Merrell Inc | Novel 4-aroylimidazol-2-ones |
| NZ193935A (en) * | 1979-06-18 | 1985-05-31 | Richardson Merrell Inc | 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions |
| PH18106A (en) * | 1981-02-18 | 1985-03-21 | Merrell Dow Pharma | Novel-4-aroylimidazol-2-ones |
-
1981
- 1981-10-23 US US06/314,312 patent/US4405628A/en not_active Expired - Lifetime
-
1982
- 1982-03-01 IL IL65137A patent/IL65137A/xx not_active IP Right Cessation
- 1982-03-01 PH PH26929A patent/PH18345A/en unknown
- 1982-03-01 CA CA000397351A patent/CA1190550A/en not_active Expired
- 1982-03-02 AU AU81037/82A patent/AU557590B2/en not_active Ceased
- 1982-03-02 GR GR67455A patent/GR76518B/el unknown
- 1982-03-02 NZ NZ199885A patent/NZ199885A/en unknown
- 1982-03-03 ES ES510087A patent/ES8305352A1/es not_active Expired
- 1982-03-04 EP EP82101706A patent/EP0059948B1/en not_active Expired
- 1982-03-04 KR KR8200933A patent/KR890000765B1/ko active
- 1982-03-04 DK DK095482A patent/DK168627B1/da not_active IP Right Cessation
- 1982-03-04 NO NO820686A patent/NO157175C/no unknown
- 1982-03-04 DE DE8282101706T patent/DE3267352D1/de not_active Expired
- 1982-03-04 GB GB8206412A patent/GB2096600B/en not_active Expired
- 1982-03-04 AT AT82101706T patent/ATE16489T1/de active
- 1982-03-04 IE IE491/82A patent/IE52387B1/en not_active IP Right Cessation
-
1983
- 1983-01-25 ES ES519254A patent/ES519254A0/es active Granted
-
1986
- 1986-08-21 HK HK616/86A patent/HK61686A/xx not_active IP Right Cessation
- 1986-12-30 MY MY700/86A patent/MY8600700A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0059948A1 (en) | 1982-09-15 |
| GR76518B (es) | 1984-08-10 |
| NZ199885A (en) | 1985-04-30 |
| MY8600700A (en) | 1986-12-31 |
| NO157175B (no) | 1987-10-26 |
| ES8402827A1 (es) | 1984-03-01 |
| US4405628A (en) | 1983-09-20 |
| AU8103782A (en) | 1982-09-09 |
| KR890000765B1 (ko) | 1989-04-05 |
| PH18345A (en) | 1985-06-05 |
| IE820491L (en) | 1982-09-05 |
| IE52387B1 (en) | 1987-10-14 |
| ATE16489T1 (de) | 1985-11-15 |
| IL65137A0 (en) | 1982-05-31 |
| CA1190550A (en) | 1985-07-16 |
| HK61686A (en) | 1986-08-29 |
| KR830009046A (ko) | 1983-12-17 |
| DK168627B1 (da) | 1994-05-09 |
| EP0059948B1 (en) | 1985-11-13 |
| NO820686L (no) | 1982-09-06 |
| GB2096600B (en) | 1985-06-05 |
| NO157175C (no) | 1988-02-03 |
| GB2096600A (en) | 1982-10-20 |
| DK95482A (da) | 1982-09-06 |
| AU557590B2 (en) | 1986-12-24 |
| DE3267352D1 (en) | 1985-12-19 |
| ES519254A0 (es) | 1984-03-01 |
| IL65137A (en) | 1987-02-27 |
| ES8305352A1 (es) | 1983-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20020304 |