ES482152A1 - Un procedimiento para la preparacion de nuevas 3-fenilpro- pilaminas n-sustituidas. - Google Patents
Un procedimiento para la preparacion de nuevas 3-fenilpro- pilaminas n-sustituidas.Info
- Publication number
- ES482152A1 ES482152A1 ES482152A ES482152A ES482152A1 ES 482152 A1 ES482152 A1 ES 482152A1 ES 482152 A ES482152 A ES 482152A ES 482152 A ES482152 A ES 482152A ES 482152 A1 ES482152 A1 ES 482152A1
- Authority
- ES
- Spain
- Prior art keywords
- phenyl
- hydroxyethyl
- hydrogen
- phenylpropyl
- amines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Un procedimiento para la preparación de nuevas 3-fenilpropilaminas N-sustituidas de fórmula (I) **(fórmula-01)** donde: R(sub, 1) es hidrógeno o flúor; R(sub, 2) es hidrógeno o hidroxi; con la condición de que por lo menos uno de R(sub, 1) o R(sub, 2) sea hidrógeno; R(sub, 3) es hidroxi; C es un átomo de carbono asimétrico que tiene la configuración estereoquímica absoluta R: o una sal farmacéuticamente aceptable del mismo, cuyo procedimiento comprende: (a) someter a reacción de separación del grupo protector Q, una amina protegida de fórmula (II): **(fórmula-02)** donde R(sub, 1) es el definido anteriormente, R(sub, 4) y R(sub, 5) son respectivamente R(sub, 2) y R(sub, 3) o independientemente pueden representar -OQ; y (b) cuando se desea, resolver las mezclas racémicas de los prductos no ópticamente activos en el isómero R ópticamente activo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92166678A | 1978-07-03 | 1978-07-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES482152A1 true ES482152A1 (es) | 1980-08-16 |
Family
ID=25445781
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES482152A Expired ES482152A1 (es) | 1978-07-03 | 1979-07-03 | Un procedimiento para la preparacion de nuevas 3-fenilpro- pilaminas n-sustituidas. |
| ES490208A Granted ES490208A0 (es) | 1978-07-03 | 1980-04-01 | Un procedimiento para la preparacion de nuevas 3-fenilpropi-laminas n-sustituidas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES490208A Granted ES490208A0 (es) | 1978-07-03 | 1980-04-01 | Un procedimiento para la preparacion de nuevas 3-fenilpropi-laminas n-sustituidas |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP0007716A1 (es) |
| JP (1) | JPS559099A (es) |
| AR (1) | AR221733A1 (es) |
| AT (1) | ATA463879A (es) |
| AU (1) | AU4848679A (es) |
| BE (1) | BE877390A (es) |
| CA (1) | CA1126296A (es) |
| CS (1) | CS208752B2 (es) |
| DD (1) | DD144764A5 (es) |
| DK (1) | DK268479A (es) |
| ES (2) | ES482152A1 (es) |
| FI (1) | FI792078A (es) |
| FR (1) | FR2430407A1 (es) |
| GB (1) | GB2028801A (es) |
| GR (1) | GR73049B (es) |
| IL (1) | IL57669A0 (es) |
| LU (1) | LU81454A1 (es) |
| NZ (1) | NZ190862A (es) |
| PH (1) | PH15477A (es) |
| PL (1) | PL117485B1 (es) |
| PT (1) | PT69842A (es) |
| RO (1) | RO77727A (es) |
| ZA (1) | ZA793294B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0103830A3 (de) * | 1982-09-22 | 1985-07-31 | Bayer Ag | Wachstumsfördernde Phenylethylamin-Derivate |
| US5643967A (en) * | 1983-01-31 | 1997-07-01 | Eli Lilly And Company | Growth promotion |
| US4849453A (en) * | 1983-01-31 | 1989-07-18 | Eli Lilly And Company | Growth promotion |
| CA1247451A (en) * | 1983-01-31 | 1988-12-28 | David B. Anderson | Phenethanolamines |
| CN1073983C (zh) * | 1994-10-31 | 2001-10-31 | 中国科学院成都有机化学研究所 | 一种β－拟肾上腺素兴奋剂型饲料添加剂的合成方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6610530A (es) * | 1966-07-27 | 1968-01-29 |
-
1979
- 1979-06-26 IL IL57669A patent/IL57669A0/xx unknown
- 1979-06-26 CA CA330,567A patent/CA1126296A/en not_active Expired
- 1979-06-26 DK DK268479A patent/DK268479A/da unknown
- 1979-06-27 PH PH22701A patent/PH15477A/en unknown
- 1979-06-27 NZ NZ190862A patent/NZ190862A/xx unknown
- 1979-06-28 AU AU48486/79A patent/AU4848679A/en not_active Abandoned
- 1979-06-28 PT PT69842A patent/PT69842A/pt unknown
- 1979-06-29 FR FR7916990A patent/FR2430407A1/fr active Granted
- 1979-07-02 EP EP79301281A patent/EP0007716A1/en not_active Withdrawn
- 1979-07-02 RO RO7998008A patent/RO77727A/ro unknown
- 1979-07-02 LU LU81454A patent/LU81454A1/xx unknown
- 1979-07-02 JP JP8489379A patent/JPS559099A/ja active Pending
- 1979-07-02 BE BE1/9441A patent/BE877390A/fr unknown
- 1979-07-02 GR GR59487A patent/GR73049B/el unknown
- 1979-07-02 FI FI792078A patent/FI792078A/fi not_active Application Discontinuation
- 1979-07-02 CS CS794628A patent/CS208752B2/cs unknown
- 1979-07-02 GB GB7922954A patent/GB2028801A/en not_active Withdrawn
- 1979-07-03 ES ES482152A patent/ES482152A1/es not_active Expired
- 1979-07-03 AT AT0463879A patent/ATA463879A/de not_active Application Discontinuation
- 1979-07-03 PL PL1979216813A patent/PL117485B1/pl unknown
- 1979-07-03 AR AR277163A patent/AR221733A1/es active
- 1979-07-03 ZA ZA793294A patent/ZA793294B/xx unknown
- 1979-07-03 DD DD79214072A patent/DD144764A5/de unknown
-
1980
- 1980-04-01 ES ES490208A patent/ES490208A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DK268479A (da) | 1980-01-04 |
| GR73049B (es) | 1984-01-26 |
| CS208752B2 (en) | 1981-09-15 |
| NZ190862A (en) | 1981-11-19 |
| IL57669A0 (en) | 1979-10-31 |
| GB2028801A (en) | 1980-03-12 |
| JPS559099A (en) | 1980-01-22 |
| AR221733A1 (es) | 1981-03-13 |
| PL117485B1 (en) | 1981-08-31 |
| AU4848679A (en) | 1980-01-10 |
| EP0007716A1 (en) | 1980-02-06 |
| RO77727A (ro) | 1981-11-24 |
| PL216813A1 (es) | 1980-03-24 |
| LU81454A1 (fr) | 1979-10-30 |
| FI792078A (fi) | 1980-01-04 |
| FR2430407A1 (fr) | 1980-02-01 |
| ZA793294B (en) | 1981-02-25 |
| DD144764A5 (de) | 1980-11-05 |
| PT69842A (en) | 1979-07-01 |
| FR2430407B1 (es) | 1981-08-14 |
| BE877390A (fr) | 1980-01-02 |
| PH15477A (en) | 1983-01-27 |
| ES8104188A1 (es) | 1981-04-16 |
| ATA463879A (de) | 1981-10-15 |
| ES490208A0 (es) | 1981-04-16 |
| CA1126296A (en) | 1982-06-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8104189A1 (es) | Un procedimiento para la preparacion de derivados de feneta-nolamina | |
| DE3574137D1 (en) | Pyridazinones, their preparation and use, medicaments containing pyridazinones | |
| AU529426B2 (en) | 4-amino-2-ureido-pyrimidine-5-carboxylic acid anilides and their use in treating lipometabolism disturbances and adiposity | |
| ES8101537A1 (es) | Un procedimiento para preparar nuevas fenetanolaminas | |
| ES8105265A1 (es) | Un procedimiento para la preparacion de fenetanolaminas | |
| ES405983A1 (es) | Procedimiento para la preparacion de derivados de fenileti-lamina fluoralcohilados. | |
| PT65697B (pt) | Procede pour la preparation de steroides avec des anneaux a 15 atomes de carbone | |
| ATE141802T1 (de) | Illudin-analoge, verwendet als antitumormittel | |
| ES482152A1 (es) | Un procedimiento para la preparacion de nuevas 3-fenilpro- pilaminas n-sustituidas. | |
| ATE41146T1 (de) | Irreversible dopamin-b-hydroxylase-inhibitoren. | |
| ES8603809A1 (es) | Un procedimiento para preparar un derivado de fluoralilamina | |
| NO850580L (no) | Isoksazol-derivater, fremgangsmaate til deres fremstilling, legemidler inneholdende disse forbindelser | |
| NO167865C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive 14,17beta-ethano-14beta-oestratrienderivater. | |
| ES440395A1 (es) | Procedimiento para la produccion de esteres de acidos piri- midiniltionofosfonicos. | |
| DK412082A (da) | 2-amino-1,2,3,4-tetrahydro-naphthalenderivater, fremgangsmaade til deres fremstilling samt deres anvendelse | |
| ES476449A1 (es) | Procedimiento de preparacion de derivados de piridazinona. | |
| ES477076A1 (es) | Un procedimiento de preparacion de derivados de acido 1-naf-til-acetico. | |
| AU527523B2 (en) | Hexahydro-1,4-oxazepines | |
| DK61785D0 (da) | 2-alkoxyaminosulfonylbenzensulfonylurinstofderivater, deres fremstilling og anvendelse som herbicider | |
| ES8308317A1 (es) | Procedimiento de preparacion de nuevos derivados de 2-fenilmorfolina. | |
| FR2450835A2 (fr) | Derives de la tetrahydroalstonine et leur application en therapeutique | |
| IE812975L (en) | Use of azolylglycols as plant growth regulants | |
| ES8600736A1 (es) | Procedimiento para la preparacion de derivados indanilicos | |
| ES481271A1 (es) | Procedimiento de preparacion de derivados de la l-cisteina. | |
| ES8303405A1 (es) | Procedimiento de preparacion de derivados de quinidina. |