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ES463424A1 - Procedimiento de preparacion de lactamas sustituidas en n. - Google Patents

Procedimiento de preparacion de lactamas sustituidas en n.

Info

Publication number
ES463424A1
ES463424A1 ES463424A ES463424A ES463424A1 ES 463424 A1 ES463424 A1 ES 463424A1 ES 463424 A ES463424 A ES 463424A ES 463424 A ES463424 A ES 463424A ES 463424 A1 ES463424 A1 ES 463424A1
Authority
ES
Spain
Prior art keywords
substituted lactams
hydrogen atom
ethylene
carbon atoms
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES463424A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB SA
Original Assignee
UCB SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB SA filed Critical UCB SA
Publication of ES463424A1 publication Critical patent/ES463424A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C07D223/10—Oxygen atoms attached in position 2

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Procedimiento de preparación de lactamas sustituídas en N que responden a la fórmula general: *(Ver fórmula I)*.
ES463424A 1976-10-22 1977-10-21 Procedimiento de preparacion de lactamas sustituidas en n. Expired ES463424A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB43934/76A GB1539817A (en) 1976-10-22 1976-10-22 N-substituted lactams

Publications (1)

Publication Number Publication Date
ES463424A1 true ES463424A1 (es) 1978-07-16

Family

ID=10431009

Family Applications (1)

Application Number Title Priority Date Filing Date
ES463424A Expired ES463424A1 (es) 1976-10-22 1977-10-21 Procedimiento de preparacion de lactamas sustituidas en n.

Country Status (27)

Country Link
US (1) US4162325A (es)
JP (1) JPS5839148B2 (es)
AT (1) AT352742B (es)
BE (1) BE859925A (es)
BG (1) BG28413A3 (es)
CA (1) CA1095040A (es)
CH (1) CH625214A5 (es)
CS (1) CS200231B2 (es)
CY (1) CY1037A (es)
DD (1) DD131930A5 (es)
DE (1) DE2747369A1 (es)
DK (1) DK461877A (es)
ES (1) ES463424A1 (es)
FI (1) FI66600C (es)
FR (1) FR2368474B1 (es)
GB (1) GB1539817A (es)
HK (1) HK2380A (es)
HU (1) HU174864B (es)
IL (1) IL53171A (es)
KE (1) KE3013A (es)
MY (1) MY8000264A (es)
NL (1) NL7711414A (es)
PL (1) PL110679B1 (es)
SE (1) SE425782B (es)
SU (2) SU805945A3 (es)
YU (1) YU251977A (es)
ZA (1) ZA776260B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2960194D1 (en) * 1978-05-08 1981-04-16 Ucb Sa Lactam-n-acetic acids, their amides, process for their preparation and therapeutic compositions containing them
EP0115473A3 (de) * 1983-01-27 1987-01-21 Ciba-Geigy Ag Substituierte Pyrrolidinonderivate und Verfahren zu ihrer Herstellung
FI840260A (fi) * 1983-01-27 1984-07-28 Ciba Geigy Ag Pyrrolidinonderivat och foerfarande foer deras framstaellning.
IT1190378B (it) * 1985-06-21 1988-02-16 Isf Spa Derivati pirrolidonici
US5118811A (en) * 1989-04-13 1992-06-02 Japan Tobacco Inc. Amino acid derivatives possessing prolyl endopeptidase-inhibitory activities
US5206386A (en) * 1991-03-20 1993-04-27 Isp Investments Inc. Controlled release N-substituted pyrrolidone esters and process for the use thereof
DE4308034A1 (de) * 1993-03-13 1994-09-15 Cassella Ag Neue Heterocyclen, ihre Herstellung und ihre Verwendung
US5658940A (en) * 1995-10-06 1997-08-19 Celgene Corporation Succinimide and maleimide cytokine inhibitors
US5914332A (en) * 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
CN114685342B (zh) * 2020-12-25 2024-05-10 长沙博源医疗科技有限公司 一种左乙拉西坦衍生物、免疫原、抗左乙拉西坦特异性抗体及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3121723A (en) * 1955-11-02 1964-02-18 Sterling Drug Inc Lower alkyl n-(tertiary-amino-lower-alkyl) lower alkamates and quaternary ammonium salts thereof
GB1039113A (en) * 1964-08-06 1966-08-17 Ucb Sa New n-substituted lactams
NL7407140A (nl) * 1974-03-07 1975-09-09 Jose Maria Espinos Taya En Jos Werkwijze voor de bereiding van een n-gesub- stitueerd pyrrolidon.
AT360980B (de) * 1976-01-14 1981-02-10 Pliva Pharm & Chem Works Verfahren zur herstellung von n-alkylamiden des 2-oxo-1-pyrrolidins

Also Published As

Publication number Publication date
FI66600C (fi) 1984-11-12
FI773069A (fi) 1978-04-23
CH625214A5 (es) 1981-09-15
ZA776260B (en) 1978-07-26
FR2368474B1 (fr) 1980-08-08
SU937450A1 (ru) 1982-06-23
FR2368474A1 (es) 1978-05-19
PL110679B1 (en) 1980-07-31
MY8000264A (en) 1980-12-31
YU251977A (en) 1983-01-21
HU174864B (hu) 1980-03-28
CS200231B2 (en) 1980-08-29
DE2747369A1 (de) 1978-04-27
NL7711414A (nl) 1978-04-25
SE7711667L (sv) 1978-04-23
CY1037A (en) 1980-08-01
BE859925A (fr) 1978-04-20
SE425782B (sv) 1982-11-08
BG28413A3 (en) 1980-04-15
GB1539817A (en) 1979-02-07
JPS5353649A (en) 1978-05-16
IL53171A (en) 1982-02-28
IL53171A0 (en) 1977-12-30
AT352742B (de) 1979-10-10
DD131930A5 (de) 1978-08-09
FI66600B (fi) 1984-07-31
JPS5839148B2 (ja) 1983-08-27
PL201601A1 (pl) 1979-01-29
KE3013A (en) 1980-02-01
ATA749677A (de) 1979-03-15
DE2747369C2 (es) 1987-11-12
DK461877A (da) 1978-04-23
US4162325A (en) 1979-07-24
HK2380A (en) 1980-01-25
CA1095040A (en) 1981-02-03
SU805945A3 (ru) 1981-02-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980504