ES461334A1 - A procedure for the preparation of aminoalquilfurans. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of aminoalquilfurans. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES461334A1 ES461334A1 ES461334A ES461334A ES461334A1 ES 461334 A1 ES461334 A1 ES 461334A1 ES 461334 A ES461334 A ES 461334A ES 461334 A ES461334 A ES 461334A ES 461334 A1 ES461334 A1 ES 461334A1
- Authority
- ES
- Spain
- Prior art keywords
- aminoalquilfurans
- translation
- procedure
- preparation
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000003710 Histamine H2 Receptors Human genes 0.000 abstract 1
- 108090000050 Histamine H2 Receptors Proteins 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 230000027119 gastric acid secretion Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/64—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Novel aminoalkylfuran derivatives of the general formula I: < IMAGE > in which the symbols have the meaning given in claim 1, are prepared by reacting a compound of the formula (II) or (III) < IMAGE > with a compound of the formula < IMAGE >. The aminoalkylfuran derivative may be used in the form of the free base or in the form of a physiologically acceptable salt or a hydrate. These novel aminoalkylfuran derivatives inhibit gastric acid secretion when this secretion is stimulated by way of histamine H2 receptors.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB32465/76A GB1565966A (en) | 1976-08-04 | 1976-08-04 | Aminoalkyl furan derivatives |
GB5068576 | 1976-12-06 | ||
GB2018777 | 1977-05-13 | ||
KR7701808A KR810000355B1 (en) | 1977-05-13 | 1977-08-04 | Preparation for pharmacologically active compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ES461334A1 true ES461334A1 (en) | 1979-05-16 |
Family
ID=27448487
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES461334A Expired ES461334A1 (en) | 1976-08-04 | 1977-08-03 | A procedure for the preparation of aminoalquilfurans. (Machine-translation by Google Translate, not legally binding) |
ES470836A Expired ES470836A1 (en) | 1976-08-04 | 1978-06-15 | A procedure for the preparation of aminoalquilfurans (Machine-translation by Google Translate, not legally binding) |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES470836A Expired ES470836A1 (en) | 1976-08-04 | 1978-06-15 | A procedure for the preparation of aminoalquilfurans (Machine-translation by Google Translate, not legally binding) |
Country Status (16)
Country | Link |
---|---|
AT (1) | AT375931B (en) |
CH (2) | CH642072A5 (en) |
CY (1) | CY1077A (en) |
DE (2) | DE2760097C2 (en) |
DK (2) | DK148258C (en) |
ES (2) | ES461334A1 (en) |
FI (1) | FI72318C (en) |
HK (1) | HK55780A (en) |
IE (1) | IE45456B1 (en) |
IT (2) | IT1126759B (en) |
KE (1) | KE3080A (en) |
NZ (2) | NZ184759A (en) |
PH (1) | PH13540A (en) |
PT (1) | PT66874B (en) |
SE (3) | SE437373B (en) |
YU (2) | YU40006B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4203909A (en) * | 1978-09-26 | 1980-05-20 | Bristol-Myers Company | Furan compounds |
YU52598A (en) * | 1998-11-19 | 2001-05-28 | D.D. Zdravlje- sektor za istraživanje i razvoj | Procedure for synthesis of n-[2[[[5-[ (dialkylamino)methyl] -2-furanil]methyl]thi0]etyl]-n'-alkyl-2-nitro 1,1 alkendiamine and its hydrochloride |
-
1977
- 1977-07-22 FI FI772264A patent/FI72318C/en not_active IP Right Cessation
- 1977-07-22 CY CY1277A patent/CY1077A/en unknown
- 1977-07-25 SE SE7708521A patent/SE437373B/en not_active IP Right Cessation
- 1977-07-25 IE IE1536/77A patent/IE45456B1/en not_active IP Right Cessation
- 1977-07-26 DK DK337977A patent/DK148258C/en not_active IP Right Cessation
- 1977-07-27 NZ NZ184759A patent/NZ184759A/en unknown
- 1977-07-27 NZ NZ191383A patent/NZ191383A/en unknown
- 1977-07-28 DE DE2760097A patent/DE2760097C2/de not_active Expired
- 1977-07-28 DE DE2759959A patent/DE2759959C2/de not_active Expired
- 1977-07-29 CH CH938077A patent/CH642072A5/en not_active IP Right Cessation
- 1977-08-01 PT PT66874A patent/PT66874B/en unknown
- 1977-08-02 PH PH20057A patent/PH13540A/en unknown
- 1977-08-03 YU YU1911/77A patent/YU40006B/en unknown
- 1977-08-03 IT IT50551/77A patent/IT1126759B/en active Protection Beyond IP Right Term
- 1977-08-03 ES ES461334A patent/ES461334A1/en not_active Expired
- 1977-08-04 AT AT0574077A patent/AT375931B/en not_active IP Right Cessation
-
1978
- 1978-06-15 ES ES470836A patent/ES470836A1/en not_active Expired
-
1980
- 1980-08-30 KE KE3080A patent/KE3080A/en unknown
- 1980-10-02 HK HK557/80A patent/HK55780A/en unknown
-
1982
- 1982-08-27 CH CH509282A patent/CH641176A5/en not_active IP Right Cessation
- 1982-09-03 YU YU2000/82A patent/YU40088B/en unknown
- 1982-09-28 SE SE8205533A patent/SE454882B/en not_active IP Right Cessation
- 1982-11-17 SE SE8206556A patent/SE454883B/en not_active IP Right Cessation
-
1984
- 1984-08-30 DK DK416384A patent/DK149952C/en not_active IP Right Cessation
-
1985
- 1985-08-01 IT IT48437/85A patent/IT1221058B/en active
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GD1A | Contractual licences |
Effective date: 19960913 |
|
GC1A | Exploitation certificate registered application without search report |
Effective date: 19960904 |
|
GD1A | Contractual licences |
Effective date: 19960913 |
|
FD1A | Patent lapsed |
Effective date: 19990311 |