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ES464068A1 - Procedimiento para la obtencion de derivados de quinclona - Google Patents

Procedimiento para la obtencion de derivados de quinclona

Info

Publication number
ES464068A1
ES464068A1 ES464068A ES464068A ES464068A1 ES 464068 A1 ES464068 A1 ES 464068A1 ES 464068 A ES464068 A ES 464068A ES 464068 A ES464068 A ES 464068A ES 464068 A1 ES464068 A1 ES 464068A1
Authority
ES
Spain
Prior art keywords
quinolone derivatives
ch3o
formula
image
acid addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES464068A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES464068A1 publication Critical patent/ES464068A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Nuevos compuestos que se pudiesen emplear como medicamentos. Los derivados de quinolona con buena compatibilidad, poseen valiosas propiedades farmacológicas. Así muestran especialmente efectos inhibidores de la agregación de tromocitos. Se presentan propiedades reductoras del azúcar de la sangre y antiflogísticas, que asimismo se pueden determinar según métodos para ello usuales. Los derivados de quinolona de fórmula I se pueden emplear, por lo tanto, como medicamentos en la medicina humana y veterinaria. Además se pueden utilizar como productos intermedios para la obtención de ulteriores medicamentos.
ES464068A 1976-11-12 1977-11-11 Procedimiento para la obtencion de derivados de quinclona Expired ES464068A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762651581 DE2651581A1 (de) 1976-11-12 1976-11-12 Chinolonderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ES464068A1 true ES464068A1 (es) 1979-01-01

Family

ID=5992974

Family Applications (1)

Application Number Title Priority Date Filing Date
ES464068A Expired ES464068A1 (es) 1976-11-12 1977-11-11 Procedimiento para la obtencion de derivados de quinclona

Country Status (15)

Country Link
US (1) US4168312A (es)
JP (1) JPS5363387A (es)
AT (1) AT361928B (es)
AU (1) AU510306B2 (es)
BE (1) BE860707A (es)
CA (1) CA1099721A (es)
DE (1) DE2651581A1 (es)
ES (1) ES464068A1 (es)
FR (1) FR2375215A1 (es)
GB (1) GB1547729A (es)
HU (1) HU175130B (es)
IL (1) IL53326A0 (es)
NL (1) NL7712447A (es)
SE (1) SE7712725L (es)
ZA (1) ZA776752B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5412104A (en) * 1990-09-07 1995-05-02 Schering Corporation Ester and alkoxy substituted benzopyrans
US5179093A (en) * 1991-05-10 1993-01-12 Schering Corporation Quinoline-diones
DE19839499A1 (de) * 1998-08-29 2000-03-02 Merck Patent Gmbh 2-Oxo-2H-chinolinderivate

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2962523A (en) * 1958-07-24 1960-11-29 Monsanto Chemicals Preparation of esters through the acylation of octahydro-5ah, 10ah-4a, 9a-epoxydibenzo-p-dioxin-5a, 10a-diol
CH471784A (de) * 1966-01-26 1969-04-30 Bayer Ag Verfahren zur Herstellung von Carbostyrilderivaten
US3635985A (en) * 1969-02-01 1972-01-18 Dainippon Pharmaceutical Co 3-phenyl-4-acyloxycarbostyrils
NL7314812A (es) * 1972-11-02 1974-05-06
US4065457A (en) * 1973-05-19 1977-12-27 Beecham Group Limited 4-Hydroxy-3-nitro-carbostyril compounds
SE431451B (sv) * 1973-10-24 1984-02-06 Otsuka Pharma Co Ltd Forfarande for framstellning av 2,3-dihydroxipropoxikinoliner eller -isokinoliner

Also Published As

Publication number Publication date
US4168312A (en) 1979-09-18
FR2375215A1 (fr) 1978-07-21
SE7712725L (sv) 1978-05-13
IL53326A0 (en) 1978-01-31
ZA776752B (en) 1978-09-27
DE2651581A1 (de) 1978-05-18
CA1099721A (en) 1981-04-21
NL7712447A (nl) 1978-05-17
HU175130B (hu) 1980-05-28
JPS5363387A (en) 1978-06-06
AU510306B2 (en) 1980-06-19
BE860707A (fr) 1978-05-10
AU3054677A (en) 1979-05-17
AT361928B (de) 1981-04-10
ATA803977A (de) 1980-09-15
GB1547729A (en) 1979-06-27

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