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ES423976A1 - Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES423976A1
ES423976A1 ES423976A ES423976A ES423976A1 ES 423976 A1 ES423976 A1 ES 423976A1 ES 423976 A ES423976 A ES 423976A ES 423976 A ES423976 A ES 423976A ES 423976 A1 ES423976 A1 ES 423976A1
Authority
ES
Spain
Prior art keywords
signifies
group
procedure
formula
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES423976A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2316325A external-priority patent/DE2316325A1/en
Priority claimed from DE19732320967 external-priority patent/DE2320967C3/en
Priority claimed from DE2346743A external-priority patent/DE2346743C3/en
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES423976A1 publication Critical patent/ES423976A1/en
Expired legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Procedure for the preparation of new benzylamines of the general formula I, **(See formula)** where Hal signifies a chlorine or bromine atom, R1 signifies a hydrogen, chlorine or bromine atom, R2 signifies the morpholinocarbonylmethyl radical, a branched alcohol radical with 3 to 5 carbon atoms, optionally substituted with 1 to 3 hydroxyl groups, or a group of the formula **(See formula)** where R3 signifies a hydrogen atom, a hydroxy group or an alcohol group with 1 to 4 carbon atoms, n signifies the numbers 0, 1 or 2 and the two radicals A and B signify hydrogen atoms or together the group **(See formula)** where R5 represents a hydrogen atom or a lower alcohol radical with 1 or 2 carbon atoms and m means numbers 1 or 2, and 1 means numbers 1 or 2, as well as their physiologically acid-compatible acid addition salts. organic or inorganic, characterized in that a compound of the general formula II is hydrolyzed **(See formula)** where R1, R2, Hal and l are as initially defined; and A represents the group -CH2- or -CO- and a compound of the general formula I, obtained according to the procedure, is subsequently transformed, if desired, into its physiologically compatible salts with organic or inorganic acids. (Machine-translation by Google Translate, not legally binding)
ES423976A 1973-04-02 1974-03-06 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding) Expired ES423976A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2316325A DE2316325A1 (en) 1972-10-23 1973-04-02 Halo-hydroxy-substd-benzylamines - as secretolytic and antitussive agents
DE19732320967 DE2320967C3 (en) 1973-04-26 New benzylamines, their physiologically acceptable salts, processes for their production and pharmaceuticals containing them
DE2346743A DE2346743C3 (en) 1972-10-23 1973-09-17 2- or 4-Hydroxy-3,5-dihalogenobenzylamines, their physiologically tolerable salts, processes for their preparation and medicaments containing them

Publications (1)

Publication Number Publication Date
ES423976A1 true ES423976A1 (en) 1976-06-16

Family

ID=27185164

Family Applications (4)

Application Number Title Priority Date Filing Date
ES423976A Expired ES423976A1 (en) 1973-04-02 1974-03-06 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)
ES423974A Expired ES423974A1 (en) 1973-04-02 1974-03-06 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)
ES423975A Expired ES423975A1 (en) 1973-04-02 1974-03-06 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)
ES423973A Expired ES423973A1 (en) 1973-04-02 1974-03-14 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES423974A Expired ES423974A1 (en) 1973-04-02 1974-03-06 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)
ES423975A Expired ES423975A1 (en) 1973-04-02 1974-03-06 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)
ES423973A Expired ES423973A1 (en) 1973-04-02 1974-03-14 Procedure for the preparation of new bencilamines. (Machine-translation by Google Translate, not legally binding)

Country Status (5)

Country Link
AT (1) ATA88775A (en)
ES (4) ES423976A1 (en)
MX (1) MX3141E (en)
PL (3) PL92541B1 (en)
SU (4) SU532338A3 (en)

Also Published As

Publication number Publication date
PL91890B1 (en) 1977-03-31
PL91891B1 (en) 1977-03-31
ES423973A1 (en) 1976-06-16
SU515443A3 (en) 1976-05-25
SU512696A3 (en) 1976-04-30
SU532338A3 (en) 1976-10-15
ES423975A1 (en) 1976-06-16
PL92541B1 (en) 1977-04-30
ATA88775A (en) 1975-07-15
MX3141E (en) 1980-05-06
ES423974A1 (en) 1976-06-16
SU533333A3 (en) 1976-10-25

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