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ES424290A1 - A procedure for the preparation of new derivatives of 2-alkyl (bottom) -2 or 3-cefem-4-carboxylic acid. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of new derivatives of 2-alkyl (bottom) -2 or 3-cefem-4-carboxylic acid. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES424290A1
ES424290A1 ES74424290A ES424290A ES424290A1 ES 424290 A1 ES424290 A1 ES 424290A1 ES 74424290 A ES74424290 A ES 74424290A ES 424290 A ES424290 A ES 424290A ES 424290 A1 ES424290 A1 ES 424290A1
Authority
ES
Spain
Prior art keywords
compound
procedure
group
carboxy
acylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES74424290A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP48030719A external-priority patent/JPS5932472B2/en
Priority claimed from JP48030720A external-priority patent/JPS6024109B2/en
Priority claimed from JP3071873A external-priority patent/JPS5930715B2/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of ES424290A1 publication Critical patent/ES424290A1/en
Expired legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Cephalosporin Compounds (AREA)

Abstract

A procedure for the preparation of new derivatives of 2-lower alkyl -2 or 3-cephem-4-carboxylic acid of general formula **(See formula)** where R1 is amino or substituted amino; R2 is carboxy or protected carboxy, R3 lower alkyl and X is -S- or (see formula), or a pharmaceutically acceptable salt thereof, the procedure of which is to react with a Lewis acid a compound of the general formula: **(See formula)** where R1, R2, R3 and X are as defined above and, if desired, when X is -S-, oxidize the resulting compound to produce a compound where X is (see formula); When R1 is acylamino with a protected amino group, subject the resulting compound to an amino protecting group removal reaction to produce a compound where R1 is acylamino with an amino group; when R1 is acylamino with a protected hydroxy group, subjecting the resulting compound to a removal reaction of the hydroxy protecting group to produce the compound where R1 is acylamino with a hydroxy group; when R2 is a protected carboxy group, subject the resulting compound to a removal reaction of the carboxy protecting group to produce the compound where R2 is carboxy. (Machine-translation by Google Translate, not legally binding)
ES74424290A 1973-03-15 1974-03-14 A procedure for the preparation of new derivatives of 2-alkyl (bottom) -2 or 3-cefem-4-carboxylic acid. (Machine-translation by Google Translate, not legally binding) Expired ES424290A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP48030719A JPS5932472B2 (en) 1973-03-15 1973-03-15 Method for producing 2-alkyl-7-acylamino-2 (or 3)-cephem-4-carboxylic acids
JP48030720A JPS6024109B2 (en) 1973-03-15 1973-03-15 Method for producing 2-alkyl-7-amino-2 (or 3)-cephem-4-carboxylic acids
JP3071873A JPS5930715B2 (en) 1973-03-15 1973-03-15 Method for producing 2-alkyl-7-substituted-2 (or 3)-cephem-4-carboxylic acids

Publications (1)

Publication Number Publication Date
ES424290A1 true ES424290A1 (en) 1976-10-16

Family

ID=27287068

Family Applications (1)

Application Number Title Priority Date Filing Date
ES74424290A Expired ES424290A1 (en) 1973-03-15 1974-03-14 A procedure for the preparation of new derivatives of 2-alkyl (bottom) -2 or 3-cefem-4-carboxylic acid. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES424290A1 (en)

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