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ES2513691T3 - Preparación transdérmica - Google Patents

Preparación transdérmica Download PDF

Info

Publication number
ES2513691T3
ES2513691T3 ES10777667.6T ES10777667T ES2513691T3 ES 2513691 T3 ES2513691 T3 ES 2513691T3 ES 10777667 T ES10777667 T ES 10777667T ES 2513691 T3 ES2513691 T3 ES 2513691T3
Authority
ES
Spain
Prior art keywords
transdermal preparation
support
adhesive layer
indolone
ethylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10777667.6T
Other languages
English (en)
Inventor
Naoyuki Uchida
Yuka Takagi
Yasunori Takada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Application granted granted Critical
Publication of ES2513691T3 publication Critical patent/ES2513691T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Preparación transdermica que comprende un soporte y una capa adhesiva laminada sobre el soporte, en la que la capa adhesiva contiene 4-etilen-2(3H)-indolona y un compuesto fisiologicamente activo.

Description

imagen1
imagen2
imagen3
imagen4
imagen5

Claims (1)

  1. imagen1
ES10777667.6T 2009-05-21 2010-05-07 Preparación transdérmica Active ES2513691T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009123429 2009-05-21
JP2009123429 2009-05-21
PCT/JP2010/057807 WO2010134433A1 (ja) 2009-05-21 2010-05-07 経皮吸収製剤

Publications (1)

Publication Number Publication Date
ES2513691T3 true ES2513691T3 (es) 2014-10-27

Family

ID=43126117

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10777667.6T Active ES2513691T3 (es) 2009-05-21 2010-05-07 Preparación transdérmica

Country Status (7)

Country Link
US (1) US9238025B2 (es)
EP (1) EP2438917B1 (es)
JP (1) JP5514815B2 (es)
KR (1) KR101709361B1 (es)
CN (1) CN102361638B (es)
ES (1) ES2513691T3 (es)
WO (1) WO2010134433A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9155710B2 (en) 2011-05-31 2015-10-13 Hisamitsu Pharmaceutical Co., Inc. Ropinirole-containing patch and package thereof
JPWO2012165254A1 (ja) * 2011-05-31 2015-02-23 久光製薬株式会社 ロピニロール含有貼付剤及びその包装体
WO2014084311A1 (ja) * 2012-11-30 2014-06-05 帝國製薬株式会社 ロピニロール含有貼付剤
CN103494809B (zh) * 2013-09-26 2015-09-09 西安力邦制药有限公司 一种包含罗匹尼罗的组合物的制备方法
CN107484412B (zh) * 2015-04-15 2020-05-08 久光制药株式会社 含有罗匹尼罗的贴剂
EP3586841B1 (en) 2017-02-24 2023-12-27 Hisamitsu Pharmaceutical Co., Inc. Adhesive skin patch and packaged product thereof
US20220362214A1 (en) 2019-09-18 2022-11-17 Hisamitsu Pharmaceutical Co., Inc. Ropinirole-containing patch and method for improvng skin permeability of ropinirole
CN114727986A (zh) 2019-11-26 2022-07-08 久光制药株式会社 含罗匹尼罗的贴附剂的粘合剂层保持力提升方法及含罗匹尼罗的保持力改善的贴附剂
US20240016758A1 (en) 2020-10-29 2024-01-18 Hisamitsu Pharmaceutical Co., Inc. Ropinirole-containing patch and method for improving skin permeability of ropinirole

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452808A (en) 1982-12-07 1984-06-05 Smithkline Beckman Corporation 4-Aminoalkyl-2(3H)-indolones
GB8714371D0 (en) * 1987-06-19 1987-07-22 Smith Kline French Lab Process
JPH01190658A (ja) 1988-01-26 1989-07-31 Hokuriku Seiyaku Co Ltd フェニルアセトニトリル誘導体
GB9511366D0 (en) 1995-06-06 1995-08-02 Smithkline Beecham Plc Novel formulations
EP0833671A2 (en) 1995-06-07 1998-04-08 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
US5807570A (en) * 1995-09-29 1998-09-15 Cygnus, Inc. Transdermal administration of ropinirole and analogs thereof
DE19814087A1 (de) * 1998-03-30 1999-10-14 Lohmann Therapie Syst Lts Feuchtigkeitsaktivierbares therapeutisches System
JP2004331500A (ja) * 2001-02-16 2004-11-25 Dainippon Pharmaceut Co Ltd 血中濃度制御製剤
WO2005105741A1 (en) 2004-02-11 2005-11-10 Sun Pharmaceutical Industries Limited Substantially pure 4-[2-(di-n-propylamino)ethyl]-2(3h)-indolone hydrochloride
JP5684441B2 (ja) * 2005-12-28 2015-03-11 久光製薬株式会社 インドメタシン含有貼付剤
US20100022614A1 (en) * 2006-12-06 2010-01-28 Naohisa Kawamura Pharmaceutical composition for external application and adhesive skin patch
JP2008239497A (ja) * 2007-03-23 2008-10-09 Lintec Corp 消炎鎮痛貼付剤
WO2009107479A1 (ja) 2008-02-27 2009-09-03 久光製薬株式会社 貼付製剤
WO2009107478A1 (ja) 2008-02-27 2009-09-03 久光製薬株式会社 貼付剤及び包装体
US20120090275A1 (en) 2009-04-24 2012-04-19 Hisamitsu Pharmaceutical Co., Inc. Adhesive patch-containing package bag and method for storing adhesive patch
JPWO2012165254A1 (ja) * 2011-05-31 2015-02-23 久光製薬株式会社 ロピニロール含有貼付剤及びその包装体

Also Published As

Publication number Publication date
US20120052113A1 (en) 2012-03-01
WO2010134433A1 (ja) 2010-11-25
US9238025B2 (en) 2016-01-19
KR20120024582A (ko) 2012-03-14
EP2438917B1 (en) 2014-09-03
JPWO2010134433A1 (ja) 2012-11-08
CN102361638B (zh) 2013-07-17
EP2438917A4 (en) 2014-01-22
EP2438917A1 (en) 2012-04-11
CN102361638A (zh) 2012-02-22
JP5514815B2 (ja) 2014-06-04
KR101709361B1 (ko) 2017-02-22

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