ES2486675T3 - Análogo de péptido de oxintomodulina - Google Patents
Análogo de péptido de oxintomodulina Download PDFInfo
- Publication number
- ES2486675T3 ES2486675T3 ES10801033.1T ES10801033T ES2486675T3 ES 2486675 T3 ES2486675 T3 ES 2486675T3 ES 10801033 T ES10801033 T ES 10801033T ES 2486675 T3 ES2486675 T3 ES 2486675T3
- Authority
- ES
- Spain
- Prior art keywords
- peptide analog
- cys
- oxintomodulin peptide
- oxintomodulin
- peg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
Un análogo de péptido de oxintomodulina que comprende la secuencia de amino ácidos:**Fórmula** en la que Xaa38 es Cys, Cys-PEG o se encuentra ausente; Xaa39 es Cys, Cys-PEG o se encuentra ausente; y en la que el amino ácido C-terminal está opcionalmente amidado.
Description
Claims (1)
-
imagen1 imagen2
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28888809P | 2009-12-22 | 2009-12-22 | |
US288888P | 2009-12-22 | ||
US35257610P | 2010-06-08 | 2010-06-08 | |
US352576P | 2010-06-08 | ||
PCT/US2010/060390 WO2011087672A1 (en) | 2009-12-22 | 2010-12-15 | Oxyntomodulin peptide analogue |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2486675T3 true ES2486675T3 (es) | 2014-08-19 |
Family
ID=43587001
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES10801033.1T Active ES2486675T3 (es) | 2009-12-22 | 2010-12-15 | Análogo de péptido de oxintomodulina |
Country Status (34)
Country | Link |
---|---|
US (1) | US8367607B2 (es) |
EP (1) | EP2515928B1 (es) |
JP (1) | JP5717759B2 (es) |
KR (1) | KR101399671B1 (es) |
CN (1) | CN102740873B (es) |
AR (1) | AR079345A1 (es) |
AU (1) | AU2010341651B2 (es) |
BR (1) | BR112012017348B1 (es) |
CA (1) | CA2784671C (es) |
CL (1) | CL2012001686A1 (es) |
CO (1) | CO6551738A2 (es) |
CR (1) | CR20120338A (es) |
DK (1) | DK2515928T3 (es) |
DO (1) | DOP2012000176A (es) |
EA (1) | EA022820B1 (es) |
ES (1) | ES2486675T3 (es) |
HK (1) | HK1170941A1 (es) |
HN (1) | HN2012001321A (es) |
HR (1) | HRP20140616T1 (es) |
IL (1) | IL220161B (es) |
JO (1) | JO2976B1 (es) |
MA (1) | MA33825B1 (es) |
MX (1) | MX2012007438A (es) |
MY (1) | MY160773A (es) |
NZ (1) | NZ600731A (es) |
PE (1) | PE20121393A1 (es) |
PL (1) | PL2515928T3 (es) |
PT (1) | PT2515928E (es) |
RS (1) | RS53505B1 (es) |
SG (1) | SG181430A1 (es) |
SI (1) | SI2515928T1 (es) |
TN (1) | TN2012000302A1 (es) |
TW (1) | TWI423812B (es) |
WO (1) | WO2011087672A1 (es) |
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EP2214691B1 (en) | 2007-10-30 | 2015-09-30 | Indiana University Research and Technology Corporation | Compounds exhibiting glucagon antagonist and glp-1 agonist activity |
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2010
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