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ES2187489T3 - Composiciones farmaceuticas a base de diclofenac. - Google Patents

Composiciones farmaceuticas a base de diclofenac.

Info

Publication number
ES2187489T3
ES2187489T3 ES01119117T ES01119117T ES2187489T3 ES 2187489 T3 ES2187489 T3 ES 2187489T3 ES 01119117 T ES01119117 T ES 01119117T ES 01119117 T ES01119117 T ES 01119117T ES 2187489 T3 ES2187489 T3 ES 2187489T3
Authority
ES
Spain
Prior art keywords
diclofenac
pharmaceutical compositions
based pharmaceutical
sodium
diclofenac based
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES01119117T
Other languages
English (en)
Inventor
Alberto Reiner
Giorgio Reiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
APR Applied Pharma Research SA
Original Assignee
APR Applied Pharma Research SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by APR Applied Pharma Research SA filed Critical APR Applied Pharma Research SA
Application granted granted Critical
Publication of ES2187489T3 publication Critical patent/ES2187489T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Birds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Formulación farmacéutica de uso oral que contiene diclofenac en sal sódica o potásica junto con bicarbonatos sódicos o potásicos o mezclas de los mismos junto con excipientes y adyuvantes habituales, caracterizada porque dichos bicarbonatos sódicos o potásicos están presentes en una cantidad comprendida entre el 20 y el 80 % en peso basado en el peso de diclofenac.
ES01119117T 1996-05-17 1997-05-15 Composiciones farmaceuticas a base de diclofenac. Expired - Lifetime ES2187489T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI000992A IT1283029B1 (it) 1996-05-17 1996-05-17 Composizioni farmaceutiche a base di diclofenac

Publications (1)

Publication Number Publication Date
ES2187489T3 true ES2187489T3 (es) 2003-06-16

Family

ID=11374276

Family Applications (2)

Application Number Title Priority Date Filing Date
ES97927045T Expired - Lifetime ES2170396T3 (es) 1996-05-17 1997-05-15 Composiciones farmaceuticas a base de diclofenac.
ES01119117T Expired - Lifetime ES2187489T3 (es) 1996-05-17 1997-05-15 Composiciones farmaceuticas a base de diclofenac.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES97927045T Expired - Lifetime ES2170396T3 (es) 1996-05-17 1997-05-15 Composiciones farmaceuticas a base de diclofenac.

Country Status (24)

Country Link
EP (2) EP0906092B1 (es)
KR (1) KR100441179B1 (es)
AR (1) AR007165A1 (es)
AT (2) ATE210976T1 (es)
AU (1) AU733083B2 (es)
CA (1) CA2254144C (es)
DE (2) DE69718077T2 (es)
DK (2) DK0906092T3 (es)
EE (1) EE9800400A (es)
ES (2) ES2170396T3 (es)
HK (1) HK1043939B (es)
HR (1) HRP970269A2 (es)
IT (1) IT1283029B1 (es)
LT (1) LT4530B (es)
LV (1) LV12250B (es)
MA (1) MA24183A1 (es)
NZ (1) NZ332655A (es)
PL (1) PL188883B1 (es)
PT (2) PT906092E (es)
SK (1) SK157698A3 (es)
TW (1) TW505525B (es)
WO (1) WO1997044023A1 (es)
YU (1) YU19797A (es)
ZA (1) ZA974270B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7687542B2 (en) 1996-05-17 2010-03-30 Kowa Pharmaeuticals America, Inc. Rapidly bioavailable tablet and capsule formulations of diclofenac
DE10207394B4 (de) * 2002-02-21 2007-03-29 Lts Lohmann Therapie-Systeme Ag Geschmacksmaskierte oblatenförmige Arzneizubereitung
US20080287456A1 (en) 2004-05-28 2008-11-20 Imaginot Pty Ltd Oral Therapeutic Compound Delivery System
JO3352B1 (ar) 2005-06-17 2019-03-13 Apr Applied Pharma Res Sa صيغ دايكلوفيناك وطرق استخدامه
JP2009517346A (ja) 2005-11-28 2009-04-30 イメイジノット ピーティーワイ エルティーディー 治療用化合物の経口送達系
US7939561B2 (en) 2006-02-07 2011-05-10 Apr Applied Pharma Research S.A. Blister packaging for acute pain regimens
US7700125B2 (en) 2006-02-07 2010-04-20 Kowa Pharmaceuticals America, Inc. Moisture resistant container systems for rapidly bioavailable dosage forms
CA2771831C (en) * 2009-09-25 2018-03-06 Novartis Ag Oral pharmaceutical composition comprising diclofenac
WO2013156163A1 (en) 2012-04-19 2013-10-24 Glatt Ag Taste-masked pharmaceutical compositions containing diclofenac
MX2017015699A (es) * 2015-06-05 2018-12-11 Lupin Ltd Composiciones de acido diclofenaco.
IT201700009711A1 (it) 2017-01-30 2018-07-30 Applied Pharma Res Sodium free Diclofenac potassium oral solutions Soluzioni orali di Diclofenac potassico prive di sodio
WO2020121277A1 (en) 2018-12-14 2020-06-18 Apr Applied Pharma Research, S.A. Ready to use diclofenac stick packs
BR112022025132A2 (pt) 2020-06-10 2022-12-27 Applied Pharma Res Formulações de diclofenaco à base de açúcar biodisponíveis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3607339A1 (de) * 1986-03-06 1987-09-10 Merck Patent Gmbh Pharmazeutische zubereitung
EP0466650A2 (en) * 1990-07-11 1992-01-15 Warner-Lambert Company Improvements in non-steroidal anti-inflammatory therapy
DE4120311A1 (de) * 1991-06-20 1992-12-24 Kali Chemie Pharma Gmbh Konservierte pharmazeutische zubereitungen
ES2133454T3 (es) * 1993-09-07 1999-09-16 Gergely Gerhard Mezcla efervescente con sales alcalinas o lisinatos de principios activos acidos, insolubles o dificilmente solubles.
EP0760680A1 (en) * 1994-05-27 1997-03-12 Farmarc Nederland Bv Pharmaceutical composition
ZA959469B (en) * 1994-11-15 1996-05-15 South African Druggists Ltd Pharmaceutical composition
IE80467B1 (en) * 1995-07-03 1998-07-29 Elan Corp Plc Controlled release formulations for poorly soluble drugs

Also Published As

Publication number Publication date
DK0906092T3 (da) 2002-04-15
MA24183A1 (fr) 1997-12-31
EP0906092A1 (en) 1999-04-07
AR007165A1 (es) 1999-10-13
ITMI960992A0 (es) 1996-05-17
EE9800400A (et) 1999-06-15
EP1159960B1 (en) 2002-12-18
DE69709349D1 (de) 2002-01-31
HRP970269A2 (en) 1998-04-30
LT4530B (lt) 1999-07-26
PL329919A1 (en) 1999-04-26
CA2254144C (en) 2007-11-20
ATE210976T1 (de) 2002-01-15
TW505525B (en) 2002-10-11
SK157698A3 (en) 2000-11-07
HK1043939B (zh) 2003-05-16
DE69718077D1 (de) 2003-01-30
EP0906092B1 (en) 2001-12-19
DE69709349T2 (de) 2002-07-25
NZ332655A (en) 2000-04-28
HK1043939A1 (en) 2002-10-04
LV12250A (lv) 1999-04-20
LV12250B (en) 1999-09-20
DE69718077T2 (de) 2003-09-11
AU3167697A (en) 1997-12-09
ES2170396T3 (es) 2002-08-01
ITMI960992A1 (it) 1997-11-17
PT906092E (pt) 2002-06-28
EP1159960A1 (en) 2001-12-05
ZA974270B (en) 1998-01-30
KR20000010792A (ko) 2000-02-25
IT1283029B1 (it) 1998-04-03
PL188883B1 (pl) 2005-05-31
ATE229801T1 (de) 2003-01-15
PT1159960E (pt) 2003-03-31
AU733083B2 (en) 2001-05-03
CA2254144A1 (en) 1997-11-27
KR100441179B1 (ko) 2004-11-26
LT98160A (en) 1999-03-25
WO1997044023A1 (en) 1997-11-27
DK1159960T3 (da) 2003-03-31
YU19797A (sh) 1999-07-28

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