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ES2178268T3 - Formulaciones de liberacion controlada. - Google Patents

Formulaciones de liberacion controlada.

Info

Publication number
ES2178268T3
ES2178268T3 ES98950189T ES98950189T ES2178268T3 ES 2178268 T3 ES2178268 T3 ES 2178268T3 ES 98950189 T ES98950189 T ES 98950189T ES 98950189 T ES98950189 T ES 98950189T ES 2178268 T3 ES2178268 T3 ES 2178268T3
Authority
ES
Spain
Prior art keywords
film
active material
water
forming polymer
controlled release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98950189T
Other languages
English (en)
Inventor
John Michael Newton
Lee Fung Siew
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
BTG International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BTG International Ltd filed Critical BTG International Ltd
Application granted granted Critical
Publication of ES2178268T3 publication Critical patent/ES2178268T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Un procedimiento para producir un compuesto de liberación retardada que contiene un material activo o una forma de dosificación que contiene un material activo y una película formada a partir de una composición formadora de película que consiste en una mezcla de un polímero formador de película substancialmente insoluble en agua y amilosa, incluyendo el procedimiento el contacto del material activo o de la forma de dosificación que contiene el material activo con una solución de la composición formadora de película en un sistema de disolventes que incluye (1) agua y un (2) disolvente orgánico miscible en agua que por si mismo es capaz de disolver el polímero formador de película y eliminar el disolvente, en donde la relación de peso entre amilosa y polímero formador de película está en el intervalo de 1:2 a 3:2 y el sistema de disolventes contiene al menos un 50% de disolvente orgánico.
ES98950189T 1997-10-23 1998-10-23 Formulaciones de liberacion controlada. Expired - Lifetime ES2178268T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9722426.5A GB9722426D0 (en) 1997-10-23 1997-10-23 Controlled release formulations

Publications (1)

Publication Number Publication Date
ES2178268T3 true ES2178268T3 (es) 2002-12-16

Family

ID=10820995

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98950189T Expired - Lifetime ES2178268T3 (es) 1997-10-23 1998-10-23 Formulaciones de liberacion controlada.

Country Status (10)

Country Link
US (1) US6534549B1 (es)
EP (1) EP1024795B1 (es)
JP (2) JP2001520986A (es)
AT (1) ATE221773T1 (es)
CA (1) CA2302585C (es)
DE (1) DE69807104T2 (es)
DK (1) DK1024795T3 (es)
ES (1) ES2178268T3 (es)
GB (1) GB9722426D0 (es)
WO (1) WO1999021536A1 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6929884B2 (en) * 2001-04-19 2005-08-16 Zinc Matrix Power, Inc. Method for manufacture of films containing insoluble solids embedded in cellulose-based films
AR036797A1 (es) 2001-10-15 2004-10-06 Ferring Bv Un metodo para preparar una composicion farmaceutica que comprende acido 5-aminosalicilico para utilizar en el tratamiento de colitis ulcerosa y enfermedades de crohn
GB0203421D0 (en) * 2002-02-13 2002-04-03 Alizyme Therapeutics Ltd Composition
JP2007523664A (ja) 2003-04-23 2007-08-23 フェリング ベスローテン フェンノートシャップ 医薬組成物用サシェ
FR2862654B1 (fr) * 2003-11-20 2006-02-10 Roquette Freres Composition amylacee filmogene
EP1547601A1 (en) * 2003-12-23 2005-06-29 Ferring B.V. Coating method
WO2005097061A1 (en) * 2004-04-01 2005-10-20 Procyte Corporation Encapsulated peptide copper complexes and compositions and methods related thereto
US8048919B2 (en) * 2004-06-28 2011-11-01 Archer Daniels Midland Company Use of ethyl lactate as an excipient for pharmaceutical compositions
WO2006101855A2 (en) * 2005-03-16 2006-09-28 Procyte Corporation Methods and compositions for preventing and treating aging or photodamaged skin
US20090017110A1 (en) * 2005-05-31 2009-01-15 Capricorn Pharma Inc. Modified release formulations of anti-irritability drugs
GB0607534D0 (en) * 2006-04-13 2006-05-24 Univ London Pharmacy Colonic drug delivery formulation
BRPI0715362A2 (pt) * 2006-07-27 2013-06-18 Univ Sunderland composiÇço de revestimento compreendendo amido
US20090036414A1 (en) * 2007-08-02 2009-02-05 Mutual Pharmaceutical Company, Inc. Mesalamine Formulations
CA2719223C (en) 2008-03-27 2017-07-04 Zpower, Inc. Electrode separator
GB0808537D0 (en) 2008-05-12 2008-06-18 Archimedes Dev Ltd Compositions
FR2934467B1 (fr) * 2008-07-31 2014-08-22 Roquette Freres Forme solide pelliculee et procede de pelliculage a temperature ambiante.
EP2179727B1 (en) 2008-10-27 2013-05-29 Roquette Freres Water insoluble polymer: modified starch derivative-based film coatings for colon targeting
DE102008059206A1 (de) 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum
US9314444B2 (en) 2009-01-12 2016-04-19 Biokier, Inc. Composition and method for treatment of NASH
US9006288B2 (en) 2009-01-12 2015-04-14 Biokier, Inc. Composition and method for treatment of diabetes
PT2376077T (pt) 2009-01-12 2017-06-23 Biokier Inc Composição e método para tratamento de diabetes
EA201290158A1 (ru) 2009-09-23 2012-08-30 Биокиер, Инк. Композиция и способ лечения диабета
KR20120104975A (ko) 2009-10-01 2012-09-24 앱탈리스 파마테크, 인코포레이티드 경구 투여용 코르티코스테로이드 조성물
CA2817926A1 (en) 2010-11-15 2012-05-24 Archer Daniels Midland Company Compositions and uses thereof in converting contaminants
NO2659881T3 (es) 2012-04-30 2018-04-28
US20140271931A1 (en) * 2013-03-12 2014-09-18 Perosphere Inc. Anti-Acne Topical Films
SG11201600501UA (en) 2013-10-29 2016-02-26 Tillotts Pharma Ag A delayed release drug formulation
EP3662901B1 (en) 2018-12-07 2025-01-01 Tillotts Pharma AG Delayed release drug formulation comprising an outerlayer with an enzymatically degradable polymer, its composition and its method of manufacturing
ES2994844T3 (en) 2018-12-07 2025-02-03 Tillotts Pharma Ag Colonic drug delivery formulation
EP3662898A1 (en) 2018-12-07 2020-06-10 Tillotts Pharma AG Solid composition comprising mesalazine
EP3662900A1 (en) 2018-12-07 2020-06-10 Tillotts Pharma AG Colonic drug delivery formulation
US11896719B2 (en) 2022-01-24 2024-02-13 Calliditas Therapeutics Ab Pharmaceutical compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8926639D0 (en) * 1989-11-24 1990-01-17 Agricultural & Food Res Delayed release formulations

Also Published As

Publication number Publication date
CA2302585C (en) 2007-09-25
JP2010270335A (ja) 2010-12-02
WO1999021536A1 (en) 1999-05-06
EP1024795A1 (en) 2000-08-09
JP2001520986A (ja) 2001-11-06
DK1024795T3 (da) 2002-12-02
DE69807104D1 (de) 2002-09-12
DE69807104T2 (de) 2002-12-05
GB9722426D0 (en) 1997-12-24
US6534549B1 (en) 2003-03-18
ATE221773T1 (de) 2002-08-15
CA2302585A1 (en) 1999-05-06
EP1024795B1 (en) 2002-08-07

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