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ES2145137T3 - Membrana formada por un polimero a base de acrilonitrilo. - Google Patents

Membrana formada por un polimero a base de acrilonitrilo.

Info

Publication number
ES2145137T3
ES2145137T3 ES94917273T ES94917273T ES2145137T3 ES 2145137 T3 ES2145137 T3 ES 2145137T3 ES 94917273 T ES94917273 T ES 94917273T ES 94917273 T ES94917273 T ES 94917273T ES 2145137 T3 ES2145137 T3 ES 2145137T3
Authority
ES
Spain
Prior art keywords
polymer
permselective
membrane
cells
backbone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94917273T
Other languages
English (en)
Inventor
Frank Gentile
Molly Shoichet
Milton Harris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbot Medical Inc
Original Assignee
Cytotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytotherapeutics Inc filed Critical Cytotherapeutics Inc
Application granted granted Critical
Publication of ES2145137T3 publication Critical patent/ES2145137T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/12—Hydrolysis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G81/00—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
    • C08G81/02—Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers at least one of the polymers being obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • C08G81/024—Block or graft polymers containing sequences of polymers of C08C or C08F and of polymers of C08G
    • C08G81/025—Block or graft polymers containing sequences of polymers of C08C or C08F and of polymers of C08G containing polyether sequences
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
    • C08J5/20—Manufacture of shaped structures of ion-exchange resins
    • C08J5/22—Films, membranes or diaphragms
    • C08J5/2206—Films, membranes or diaphragms based on organic and/or inorganic macromolecular compounds
    • C08J5/2218—Synthetic macromolecular compounds
    • C08J5/2268—Synthetic macromolecular compounds based on macromolecular compounds obtained by reactions involving unsaturated carbon-to-carbon bonds, and by reactions not involving this type of bond
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2327/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Derivatives of such polymers
    • C08J2327/02—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Derivatives of such polymers not modified by chemical after-treatment
    • C08J2327/04—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Derivatives of such polymers not modified by chemical after-treatment containing chlorine atoms
    • C08J2327/06—Homopolymers or copolymers of vinyl chloride
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
    • C08J2371/02—Polyalkylene oxides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Materials For Medical Uses (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)

Abstract

SE DESCRIBE UN POLIMERO INJERTADO PERMEOSELECTIVO QUE SE FORMA CONVIRTIENDO EN SITIOS REACTIVOS INTERMEDIARIOS UNA PORCION DE GRUPOS CIANO DE UN POLIMERO PRINCIPAL QUE CONTIENE (A) UNIDADES, Y CADENAS DE POLIMEROS DE OXIDO DE POLIALQUILENO DE INJERTO PARA EL POLIMERO PRINCIPAL A TRAVES DE LOS SITIOS REACTIVOS. TANTO EL POLIMERO PRINCIPAL DE UNA RESINA POLIMERICA COMO UNA MEMBRANA DE POLIMERO PERMEOSELECTIVO PUEDEN SER INJERTADOS. CUANDO SE USA UNA RESINA, SE FORMA EN UNA MEMBRANA POLIMERICA PERMEOSELECTIVA USANDO METODOS CONOCIDOS. LA MEMBRANA PERMEOSELECTIVA RESULTANTE PUEDE ESTAR FORMADA EN FIBRAS HUECAS O EN LAMINAS PLANAS PARA LA ENCAPSULACION DE CELULAS VIVAS. LAS CELULAS ENCAPSULADAS SON ENTONCES IMPLANTADAS EN UN PACIENTE QUE NECESITA FACTORES BIOLOGICAMENTE ACTIVOS PRODUCIDOS POR LAS CELULAS. LA MEMBRANA DEL POLIMERO INJERTADO PERMEOSELECTIVO MUESTRA UNA BUENA DIFUSION MOLECULAR CON UNA MINIMA ADSORCION DE PROTEINAS.
ES94917273T 1993-04-27 1994-04-26 Membrana formada por un polimero a base de acrilonitrilo. Expired - Lifetime ES2145137T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5389993A 1993-04-27 1993-04-27

Publications (1)

Publication Number Publication Date
ES2145137T3 true ES2145137T3 (es) 2000-07-01

Family

ID=21987301

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94917273T Expired - Lifetime ES2145137T3 (es) 1993-04-27 1994-04-26 Membrana formada por un polimero a base de acrilonitrilo.

Country Status (13)

Country Link
US (2) US5720969A (es)
EP (1) EP0746582B1 (es)
JP (1) JPH08510274A (es)
KR (1) KR960701923A (es)
AT (1) ATE190633T1 (es)
AU (1) AU689477B2 (es)
CA (1) CA2157915A1 (es)
DE (1) DE69423522T2 (es)
DK (1) DK0746582T3 (es)
ES (1) ES2145137T3 (es)
FI (1) FI954774A0 (es)
NO (1) NO954266D0 (es)
WO (1) WO1994025503A1 (es)

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ES2145137T3 (es) * 1993-04-27 2000-07-01 Cytotherapeutics Inc Membrana formada por un polimero a base de acrilonitrilo.
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EP0815212A1 (en) * 1995-03-03 1998-01-07 Metabolex, Inc. Novel encapsulation process by a gelling polymer
US5837234A (en) * 1995-06-07 1998-11-17 Cytotherapeutics, Inc. Bioartificial organ containing cells encapsulated in a permselective polyether suflfone membrane
US6833408B2 (en) 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
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DE19715504C2 (de) * 1997-04-14 2000-10-26 Max Planck Gesellschaft PMMA-Membranen mit Polyethylenglykol-gekoppelten Wirksubstanzen
US6903244B1 (en) 1999-02-26 2005-06-07 University Of Utah Research Foundation Mice which are +/− or −/− for the elastin gene as models for vascular disease
US20020095157A1 (en) * 1999-07-23 2002-07-18 Bowman Steven M. Graft fixation device combination
US6179840B1 (en) 1999-07-23 2001-01-30 Ethicon, Inc. Graft fixation device and method
US7429399B2 (en) * 2001-06-18 2008-09-30 Solae, Llc Modified oilseed material
US20040219281A1 (en) * 2000-11-21 2004-11-04 Cargill, Incorporated Modified oilseed material
US6599323B2 (en) * 2000-12-21 2003-07-29 Ethicon, Inc. Reinforced tissue implants and methods of manufacture and use
US6852330B2 (en) * 2000-12-21 2005-02-08 Depuy Mitek, Inc. Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
CA2365376C (en) * 2000-12-21 2006-03-28 Ethicon, Inc. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
US7824701B2 (en) * 2002-10-18 2010-11-02 Ethicon, Inc. Biocompatible scaffold for ligament or tendon repair
US20040078090A1 (en) 2002-10-18 2004-04-22 Francois Binette Biocompatible scaffolds with tissue fragments
AU2002952993A0 (en) 2002-11-29 2002-12-12 The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland Therapeutic and diagnostic agents
US8197837B2 (en) 2003-03-07 2012-06-12 Depuy Mitek, Inc. Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof
US8226715B2 (en) * 2003-06-30 2012-07-24 Depuy Mitek, Inc. Scaffold for connective tissue repair
CN1579600A (zh) * 2003-08-06 2005-02-16 海南立昇净水科技实业有限公司 聚氯乙烯中空过滤膜及其制备方法
US10583220B2 (en) 2003-08-11 2020-03-10 DePuy Synthes Products, Inc. Method and apparatus for resurfacing an articular surface
EP1667516A4 (en) 2003-08-29 2009-11-11 Inst Medical W & E Hall METHOD FOR SELECTION OF ANIMAL MODELS FROM ANIMALS MUTAGENICALLY SUBJECTED AND THE USE OF MYB TRANSCRIPTION FACTORS FOR SCREENING
JP4427291B2 (ja) * 2003-09-03 2010-03-03 東亞合成株式会社 機能性膜の連続製造方法
US7316822B2 (en) * 2003-11-26 2008-01-08 Ethicon, Inc. Conformable tissue repair implant capable of injection delivery
US7901461B2 (en) * 2003-12-05 2011-03-08 Ethicon, Inc. Viable tissue repair implants and methods of use
US11395865B2 (en) * 2004-02-09 2022-07-26 DePuy Synthes Products, Inc. Scaffolds with viable tissue
US8137686B2 (en) 2004-04-20 2012-03-20 Depuy Mitek, Inc. Nonwoven tissue scaffold
US8221780B2 (en) * 2004-04-20 2012-07-17 Depuy Mitek, Inc. Nonwoven tissue scaffold
US8657881B2 (en) * 2004-04-20 2014-02-25 Depuy Mitek, Llc Meniscal repair scaffold
EP1766389A4 (en) 2004-05-12 2008-08-27 Inst Medical W & E Hall CELL ISOLATION PROCEDURE
CA2613480C (en) 2005-06-24 2015-10-20 The Walter And Eliza Hall Institute Of Medical Research Therapeutic pro-apoptotic bh3-like molecules and methods for generating and/or selecting the same
CN102512999B (zh) * 2006-04-11 2015-01-07 麻省理工学院 用聚丙烯腈接枝共聚物形成的抗污垢膜
US20070251883A1 (en) * 2006-04-28 2007-11-01 Niu Q Jason Reverse Osmosis Membrane with Branched Poly(Alkylene Oxide) Modified Antifouling Surface
JP5558817B2 (ja) 2006-07-18 2014-07-23 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション 痛みの処置方法および鎮痛化合物のスクリーニング方法
MX2010001993A (es) 2007-08-23 2010-03-11 Intrexon Corp Metodos y composiciones para diagnosticar una enfermedad.
JP2010540534A (ja) 2007-09-28 2010-12-24 イントレキソン コーポレーション 生体治療分子の発現のための治療遺伝子スイッチ構築物およびバイオリアクター、ならびにその使用
DK2295132T3 (en) * 2009-05-15 2016-12-05 Interface Biologics Inc Antithrombogenic hollow-fiber membranes, molding material and blood long
US20120083767A1 (en) * 2010-10-01 2012-04-05 The Johns Hopkins University Implantable bioreactor for delivery of paracrine factors
PL2734574T3 (pl) 2011-07-18 2020-05-18 Celgard Llc Materiały polimerowe modyfikowane powierzchniowo, modyfikowane funkcjonalizowane polimery, polimery funkcjonalne i sposoby
CN103301788B (zh) * 2012-03-09 2015-09-02 中国科学院大连化学物理研究所 Peg接枝改性的海藻酸盐-壳聚糖微胶囊及制备和应用
JP5682594B2 (ja) 2012-05-24 2015-03-11 横浜ゴム株式会社 変性ジエン系ポリマー
MX367858B (es) 2013-05-31 2019-09-09 Univ Utah Res Found Péptidos de conotoxina, composiciones farmacéuticas y usos de los mismos.
CA3003294A1 (en) 2015-10-27 2017-05-04 The University Of Queensland Modified epha4 and uses thereof
CN110167995B (zh) 2016-10-18 2022-07-01 界面生物公司 具有表面改性大分子的塑化pvc混合物和由其制成的制品

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Also Published As

Publication number Publication date
US5720969A (en) 1998-02-24
EP0746582B1 (en) 2000-03-15
AU6904194A (en) 1994-11-21
EP0746582A1 (en) 1996-12-11
EP0746582A4 (en) 1997-12-29
KR960701923A (ko) 1996-03-28
FI954774A (fi) 1995-10-06
NO954266L (no) 1995-10-25
DE69423522D1 (de) 2000-04-20
NO954266D0 (no) 1995-10-25
DE69423522T2 (de) 2000-09-21
ATE190633T1 (de) 2000-04-15
CA2157915A1 (en) 1994-11-10
AU689477B2 (en) 1998-04-02
US6180007B1 (en) 2001-01-30
FI954774A0 (fi) 1995-10-06
JPH08510274A (ja) 1996-10-29
WO1994025503A1 (en) 1994-11-10
DK0746582T3 (da) 2000-08-21

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