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ES2026669T3 - Procedimiento para la preparacion y el uso terapeutico de los beta-d-fenil tioxilosidos. - Google Patents

Procedimiento para la preparacion y el uso terapeutico de los beta-d-fenil tioxilosidos.

Info

Publication number
ES2026669T3
ES2026669T3 ES198888401030T ES88401030T ES2026669T3 ES 2026669 T3 ES2026669 T3 ES 2026669T3 ES 198888401030 T ES198888401030 T ES 198888401030T ES 88401030 T ES88401030 T ES 88401030T ES 2026669 T3 ES2026669 T3 ES 2026669T3
Authority
ES
Spain
Prior art keywords
thioxylosides
beta
phenyl
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888401030T
Other languages
English (en)
Inventor
Soth Samreth
Francois Bellamy
Jean Millet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fournier Industrie et Sante SAS
Original Assignee
Fournier Industrie et Sante SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fournier Industrie et Sante SAS filed Critical Fournier Industrie et Sante SAS
Application granted granted Critical
Publication of ES2026669T3 publication Critical patent/ES2026669T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE, COMO PRODUCTOS INDUSTRIALES NUEVOS, A OXIDOS ELEGIDOS DE ENTRE EL CONJUNTO QUE COMPRENDE: (I) LOS BETA-D-FENIL-TIOXILOSIDOS DE FORMULA (I) EN LA QUE R REPRESENTA UN ATOMO DE HIDROGENO, UN ATOMO DE HALOGENO, UN GRUPO NITRO O UN GRUPO CIANO, A REPRESENTA UN ATOMO DE AZUFRE O UN ATOMO DE OXIGENO, B REPRESENTA UN GRUPO CH2, CHOH O CO, Y REPRESENTA EL ATOMO DE HIDROGENO O UN GRUPO ACILO; Y (II) SUS EPIMEROS CUANDO B ES CHOH. ESTOS PRODUCTOS SON UTILES EN TERAPEUTICA COMO AGENTES ANTITROMBOTICOS.
ES198888401030T 1987-05-04 1988-04-27 Procedimiento para la preparacion y el uso terapeutico de los beta-d-fenil tioxilosidos. Expired - Lifetime ES2026669T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8706237A FR2614893B1 (fr) 1987-05-04 1987-05-04 Nouveaux b-d-phenyl-thioxylosides, leur procede de preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ES2026669T3 true ES2026669T3 (es) 1992-05-01

Family

ID=9350723

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888401030T Expired - Lifetime ES2026669T3 (es) 1987-05-04 1988-04-27 Procedimiento para la preparacion y el uso terapeutico de los beta-d-fenil tioxilosidos.

Country Status (29)

Country Link
US (2) US4877808A (es)
EP (1) EP0290321B1 (es)
JP (1) JPH07103144B2 (es)
KR (1) KR960015109B1 (es)
CN (1) CN1020614C (es)
AT (1) ATE68000T1 (es)
AU (1) AU602210B2 (es)
CA (1) CA1323373C (es)
CZ (1) CZ278365B6 (es)
DD (1) DD269852A5 (es)
DE (1) DE3865230D1 (es)
DK (1) DK169873B1 (es)
ES (1) ES2026669T3 (es)
FI (1) FI87655C (es)
FR (1) FR2614893B1 (es)
GR (1) GR3003415T3 (es)
HU (1) HU203362B (es)
IE (1) IE61386B1 (es)
IL (1) IL86133A (es)
MA (1) MA21260A1 (es)
NO (1) NO167035C (es)
NZ (1) NZ224447A (es)
OA (1) OA08840A (es)
PT (1) PT87382B (es)
SK (1) SK278297B6 (es)
SU (1) SU1567124A3 (es)
TN (1) TNSN88041A1 (es)
YU (1) YU46711B (es)
ZA (1) ZA883031B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63544B1 (en) * 1988-10-18 1995-05-17 Fournier Ind & Sante Novel Beta-d-phenylthioxylosides their method of preparation and their use in therapy
US5246961A (en) * 1988-10-18 1993-09-21 Fournier Industrie Et Sante β-d-phenylthioxylosides, and their use as therapeutic agents
FR2648819B1 (fr) * 1989-06-21 1994-11-25 Fournier Innovation Synergie Nouveaux (beta)-d-phenyl-thioxylosides, leur procede de preparation et leur utilisation en therapeutique
FR2652353B1 (fr) * 1989-09-22 1994-02-11 Fournier Industrie Sante Nouveaux benzopyran-2-one-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.
ATE113956T1 (de) * 1989-09-22 1994-11-15 Fournier Ind & Sante Benzopyranon-beta-d-thioxyloside, verfahren zu ihrer herstellung und ihre therapeutische verwendung.
FR2659659B1 (fr) * 1990-03-16 1995-03-10 Fournier Ind & Sante Nouveaux benzopyran-4-one-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.
FR2660313B1 (fr) * 1990-04-02 1992-07-03 Fournier Ind & Sante Nouveau sulfonyl-phenyl-betha-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.
FR2688221B1 (fr) * 1992-03-09 1994-05-20 Fournier Industrie Sante Estratrienol-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.
WO1994020116A1 (en) * 1993-03-10 1994-09-15 University Of Alabama Research Foundation Artificial primers for glycogen synthesis
HUP9601756A3 (en) * 1996-06-25 1999-05-28 Richter Gedeon Vegyeszet New anticoagulant glycosides and pharmaceutical compositions containing them
HUP9603341A3 (en) * 1996-12-04 1999-05-28 Richter Gedeon Vegyeszet Glucosides as blood-clotting-inhibitors and pharmaceutical compositions containing them
SK20122000A3 (sk) * 1998-06-24 2001-07-10 Fournier Industrie Et Sante Zlúčeniny odvodené od alfa-d-xylózy, spôsob ich prípravy, farmaceutický prostriedok a terapeutické použitie
US6291433B1 (en) 1999-06-11 2001-09-18 Fournier Industrie Et Sante Derivatives of α-D-Thioxyloside and their use against atheroma
DE10300049A1 (de) * 2003-01-03 2004-07-15 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen, die Faktor VIIa inhibieren
DE50308492D1 (de) * 2002-01-31 2007-12-13 Morphochem Ag Komb Chemie Verbindungen, die faktor xa-aktiv t inhibieren
FR2860234B1 (fr) * 2003-09-25 2005-12-23 Fournier Lab Sa Nouveaux derives 666 du thioxylose
FR2883561B1 (fr) * 2005-03-25 2009-03-20 Fournier S A Sa Lab Nouveaux composes derives du 5-thioxylose et leur utilisation therapeutique
FR2903698B1 (fr) * 2006-07-13 2009-01-30 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose.
FR2906247B1 (fr) * 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose
FR2906248B1 (fr) * 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3243425A (en) * 1962-10-29 1966-03-29 Purdue Research Foundation Novel sulfur-containing compounds
US3949002A (en) * 1970-11-13 1976-04-06 Imperial Chemical Industries Limited Process for producing sulfone containing thiophenols
GB1585962A (en) * 1976-10-14 1981-03-11 Lilly Industries Ltd Benzophenone derivatives
FR2492830A1 (fr) * 1980-10-29 1982-04-30 Sori Soc Rech Ind Nouveaux composes appartenant a la famille des benzoyl- et a-hydroxybenzyl-phenyl-osides, leur procede de preparation et leur application en therapeutique
FR2549476B1 (fr) * 1983-07-20 1986-04-25 Rech Ind Benzyl-phenyl-osides, procede de preparation et utilisation en therapeutique
US4515782A (en) * 1983-08-29 1985-05-07 American Cyanamid Company Substituted phenyl-1-thio(poly-O-sulfo)-α(or β)-D-glucopyranosides
DE3725640A1 (de) * 1987-08-03 1989-02-23 Bayer Ag Verfahren zur herstellung von thiophenolen und neue thiophenole

Also Published As

Publication number Publication date
DD269852A5 (de) 1989-07-12
HUT46923A (en) 1988-12-28
YU86988A (en) 1989-10-31
YU46711B (sh) 1994-04-05
NO167035B (no) 1991-06-17
PT87382B (pt) 1992-08-31
DK169873B1 (da) 1995-03-20
DK239788A (da) 1988-11-05
US4877808A (en) 1989-10-31
FR2614893B1 (fr) 1989-12-22
FI87655B (fi) 1992-10-30
SU1567124A3 (ru) 1990-05-23
EP0290321B1 (fr) 1991-10-02
IE61386B1 (en) 1994-11-02
HU203362B (en) 1991-07-29
OA08840A (fr) 1989-03-31
NO881921D0 (no) 1988-05-02
CA1323373C (en) 1993-10-19
NO167035C (no) 1991-09-25
IE881324L (en) 1988-11-04
SK297988A3 (en) 1996-09-04
IL86133A0 (en) 1988-11-15
KR880013916A (ko) 1988-12-22
FR2614893A1 (fr) 1988-11-10
JPH07103144B2 (ja) 1995-11-08
JPS63280092A (ja) 1988-11-17
US4996347A (en) 1991-02-26
ATE68000T1 (de) 1991-10-15
PT87382A (pt) 1989-05-31
TNSN88041A1 (fr) 1990-07-10
ZA883031B (en) 1988-11-01
EP0290321A1 (fr) 1988-11-09
DE3865230D1 (de) 1991-11-07
FI87655C (fi) 1993-02-10
GR3003415T3 (en) 1993-02-17
SK278297B6 (en) 1996-09-04
CN1020614C (zh) 1993-05-12
IL86133A (en) 1992-05-25
AU1521988A (en) 1988-11-10
FI882043A0 (fi) 1988-05-02
NZ224447A (en) 1990-09-26
DK239788D0 (da) 1988-05-03
MA21260A1 (fr) 1988-12-31
AU602210B2 (en) 1990-10-04
CZ297988A3 (en) 1993-07-14
CZ278365B6 (en) 1993-12-15
KR960015109B1 (ko) 1996-10-28
NO881921L (no) 1988-11-07
CN88102569A (zh) 1988-12-14
FI882043A (fi) 1988-11-05

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