[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

ES2089498T3 - Comprimidos dispersables en agua. - Google Patents

Comprimidos dispersables en agua.

Info

Publication number
ES2089498T3
ES2089498T3 ES92903508T ES92903508T ES2089498T3 ES 2089498 T3 ES2089498 T3 ES 2089498T3 ES 92903508 T ES92903508 T ES 92903508T ES 92903508 T ES92903508 T ES 92903508T ES 2089498 T3 ES2089498 T3 ES 2089498T3
Authority
ES
Spain
Prior art keywords
water
dispersible
compresses
minutes
dispersant agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92903508T
Other languages
English (en)
Inventor
Krystyna Elzbieta Fielden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919102019A external-priority patent/GB9102019D0/en
Priority claimed from GB919124803A external-priority patent/GB9124803D0/en
Priority claimed from GB919124807A external-priority patent/GB9124807D0/en
Priority claimed from GB919125005A external-priority patent/GB9125005D0/en
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Application granted granted Critical
Publication of ES2089498T3 publication Critical patent/ES2089498T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glanulating (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR COMPRIMIDOS DISPERSABLES EN AGUA. UN COMPRIMIDO DISPERSABLE EN AGUA COMPRENDE UN COMPUESTO ACTIVO, TAL COMO ACICLOVIR O LAMOTRIGINA, Y UN AGENTE DISPERSANTE. EL AGENTE DISPERSANTE ES UNA ARCILLA ESPONJABLE TAL COMO UNA ESMECTITA, POR EJEMPLO, VEEGUM F O BENTONITA, Y ESTA GENERALMENTE PRESENTE DENTRO DE LOS GRANULOS DEL COMPRIMIDO PARA PROPORCIONAR UN COMPRIMIDO QUE ES CAPAZ DE DISPERSARSE EN AGUA EN 3 MINUTOS, PARA PROPORCIONAR UNA DISPERSION QUE PASA A TRAVES DE UN TAMIZ DE 710 MIM. EL COMPRIMIDO PUEDE SER OPCIONALMENTE RECUBIERTO CON PELICULA EN CUYO CASO EL TIEMPO DE DISPERSION ES MENOR QUE 5 MINUTOS.
ES92903508T 1991-01-30 1992-01-29 Comprimidos dispersables en agua. Expired - Lifetime ES2089498T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB919102019A GB9102019D0 (en) 1991-01-30 1991-01-30 Pharmaceutical formulations
GB919124803A GB9124803D0 (en) 1991-11-22 1991-11-22 Pharmaceutical formulations
GB919124807A GB9124807D0 (en) 1991-11-22 1991-11-22 Pharmaceutical formulations
GB919125005A GB9125005D0 (en) 1991-11-25 1991-11-25 Pharmaceutical formulations

Publications (1)

Publication Number Publication Date
ES2089498T3 true ES2089498T3 (es) 1996-10-01

Family

ID=27450613

Family Applications (2)

Application Number Title Priority Date Filing Date
ES92903508T Expired - Lifetime ES2089498T3 (es) 1991-01-30 1992-01-29 Comprimidos dispersables en agua.
ES09250043A Expired - Fee Related ES2080641B1 (es) 1991-01-30 1992-01-29 Procedimiento para preparar comprimidos dispersables en agua.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES09250043A Expired - Fee Related ES2080641B1 (es) 1991-01-30 1992-01-29 Procedimiento para preparar comprimidos dispersables en agua.

Country Status (37)

Country Link
US (2) US5556639A (es)
EP (1) EP0522128B1 (es)
JP (2) JP3118255B2 (es)
KR (1) KR100190254B1 (es)
AT (1) ATE133068T1 (es)
AU (2) AU653203B2 (es)
BE (1) BE1004461A5 (es)
BG (1) BG61665B2 (es)
CA (1) CA2098108C (es)
CH (1) CH685978A5 (es)
CY (1) CY2007A (es)
CZ (1) CZ286723B6 (es)
DE (2) DE4290300T1 (es)
DK (2) DK0522128T3 (es)
ES (2) ES2089498T3 (es)
FI (2) FI111605B (es)
FR (1) FR2671970B1 (es)
GB (1) GB2257363B (es)
GR (1) GR3019545T3 (es)
HK (1) HK78597A (es)
HU (2) HU221677B1 (es)
IE (1) IE77165B1 (es)
IL (1) IL100796A (es)
IT (1) IT1257473B (es)
LU (1) LU88323A1 (es)
MX (1) MX9200412A (es)
MY (2) MY110880A (es)
NL (1) NL9220009A (es)
NO (1) NO306697B1 (es)
PA (1) PA7695401A1 (es)
PL (1) PL169106B1 (es)
RU (1) RU2106861C1 (es)
SA (1) SA92120365B1 (es)
SE (1) SE9302363D0 (es)
SK (2) SK282071B6 (es)
UA (1) UA37214C2 (es)
WO (1) WO1992013527A1 (es)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9424766D0 (en) * 1994-12-07 1995-02-08 Wellcome Found Pharmaceutical composition
ES2079327B1 (es) * 1994-12-13 1996-08-01 Lilly Sa Formulaciones farmaceuticas de cefaclor.
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
GB9518465D0 (en) * 1995-09-09 1995-11-08 Smithkline Beecham Seiyaku Kk Pharmaceuticals
GB9600847D0 (en) * 1996-01-16 1996-03-20 Smithkline Beecham Plc Pharmaceuticals
FR2759706B1 (fr) * 1997-02-18 2003-11-28 Alain Perrier Procede de traitement de l'argile a des fins therapeutiques et produits obtenus par ce procede
US6129932A (en) * 1997-09-05 2000-10-10 Merck & Co., Inc. Compositions for inhibiting platelet aggregation
US5955107A (en) * 1997-12-12 1999-09-21 Fmc Corporation Pharmaceutical suspension tablet compositions
DE19820801A1 (de) * 1998-05-09 1999-11-25 Gruenenthal Gmbh Orale Arzneiformen mit reproduzierbarer Wirkstofffreisetzung von Gatifloxacin oder pharmazeutisch verwendbaren Salzen oder Hydraten
EP1135118A1 (en) 1998-11-10 2001-09-26 Teva Pharmaceutical Industries Ltd. Dispersible compositions containing l-dopa ethyl ester
PE20001302A1 (es) * 1998-11-27 2000-11-30 Hoffmann La Roche Preparaciones de una combinacion farmaceutica que contiene carvedilol e hidroclorotiazida
EP1161940B1 (en) * 1999-02-17 2005-06-08 Kyowa Hakko Kogyo Co., Ltd. Tablets and process for producing tablets
US6399591B1 (en) * 2000-01-19 2002-06-04 Yung-Shin Pharmaceutical Ind. Co., Ltd. Chargeable pharmaceutical tablets
GB0010446D0 (en) * 2000-04-28 2000-06-14 Glaxo Wellcome Kk Pharmaceutical formulation
US6555145B1 (en) * 2000-06-06 2003-04-29 Capricorn Pharma, Inc. Alternate encapsulation process and products produced therefrom
US6365209B2 (en) * 2000-06-06 2002-04-02 Capricorn Pharma, Inc. Confectionery compositions and methods of making
US6358526B1 (en) 2000-08-16 2002-03-19 Rexall Sundown Method of making tablets and tablet compositions produced therefrom
EA005497B1 (ru) * 2001-01-03 2005-02-24 Берлин Хеми Аг Применение фармацевтической композиции, содержащей бривудин, для лечения герпесвирусных инфекций
US7939102B2 (en) * 2002-06-07 2011-05-10 Torrent Pharmaceuticals Ltd. Controlled release formulation of lamotrigine
US8637512B2 (en) 2002-07-29 2014-01-28 Glaxo Group Limited Formulations and method of treatment
GB0223978D0 (en) * 2002-10-15 2002-11-20 Novartis Ag Organic compound
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
EP1608342A2 (en) * 2003-03-21 2005-12-28 Ranbaxy Laboratories, Ltd. Stable lamotrigine pharmaceutical compositions and processes for their preparation
US7282217B1 (en) 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
US20070116764A1 (en) 2003-12-01 2007-05-24 Shigeyuki Marunaka Method for treatment of solid pharmaceutical preparation prior to printing and solid pharmaceutical preparation subjected to treatment prior to printing
US8309103B2 (en) * 2004-01-22 2012-11-13 Alparis, S.A. De C.V. Association of fluconazole-tinidazole for the treatment of vaginal infections, its composition, preparation process and usage
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
US20050244493A1 (en) * 2004-04-30 2005-11-03 Withiam Michael C Rapidly disintegrating tablets comprising calcium carbonate
US20050244347A1 (en) * 2004-04-30 2005-11-03 Mehra Dev K Oral care products comprising calcium phosphates
US20070196477A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly dissolving tablets comprising low surface area calcium phosphates
CN100340235C (zh) * 2004-05-21 2007-10-03 山东绿叶制药有限公司 蒙脱石分散片及其制备工艺
US20060008492A1 (en) * 2004-07-09 2006-01-12 Pablo Janowicz Composition and method for delivering chemical agent to insects
DE102004042139B4 (de) * 2004-08-31 2009-06-10 Aristocon Verwaltungs- Gmbh Perorale Darreichungsformen zur Erzielung eines Retardierungseffektes nach der Arzneimitteleinnahme mit einer Mahlzeit
NZ560232A (en) * 2005-02-25 2010-11-26 Hoffmann La Roche Tablets with improved drug substance dispersibility
IS7724A (is) * 2005-03-02 2006-09-03 Actavis Group Samsetning á töflum með hraða sundrun sem innihalda þungt magnesíum karbónat
RS20070512A (en) * 2005-06-29 2009-01-22 Panacea Biotec Ltd., Pharmaceutical sustained release compositionsand processes thereof
EP1906937B1 (en) 2005-07-22 2016-10-19 Rubicon Research Pvt Ltd. Novel dispersible tablet composition
NZ567627A (en) * 2005-09-30 2011-08-26 Boehringer Ingelheim Vetmed Granulation process for making a divisible tablet containing meloxicam
FR2912059B1 (fr) * 2007-02-06 2013-04-05 Scras Utilisation d'argiles pour le traitement de la maladie coeliaque
WO2008104996A2 (en) * 2007-02-28 2008-09-04 Jubilant Organosys Limited Water dispersible pharmaceutical formulation and process for preparing the same
GB0708929D0 (en) * 2007-05-09 2007-06-20 Glaxosmithkline Consumer Healt Composition
GB0709541D0 (en) * 2007-05-17 2007-06-27 Jagotec Ag Pharmaceutical excipient
TWI547282B (zh) 2007-07-02 2016-09-01 愛戴爾製藥股份有限公司 樂命達之口服分解錠劑組合物
US20090022789A1 (en) * 2007-07-18 2009-01-22 Supernus Pharmaceuticals, Inc. Enhanced formulations of lamotrigine
WO2009063484A2 (en) * 2007-08-03 2009-05-22 Alkem Laboratories Ltd Stable pharmaceutical composition of lamotrigine
EP2100595A1 (en) * 2008-03-10 2009-09-16 The Procter and Gamble Company Compressed tablets
CN102105140B (zh) * 2008-07-02 2013-10-23 巴斯夫欧洲公司 涂覆片剂的方法
EP2612681B1 (en) * 2010-08-31 2019-01-30 Toray Industries, Inc. Coating agent for pharmaceutical solid preparation, pharmaceutical film formulation, and coated pharmaceutical solid preparation
USD666096S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666099S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666098S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666097S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666493S1 (en) 2010-11-01 2012-09-04 Colgate-Palmolive Company Cap for a container
USD666492S1 (en) 2010-11-01 2012-09-04 Colgate-Palmolive Company Cap for a container
RU2462243C1 (ru) * 2011-08-17 2012-09-27 Вемур Инвестментс Лимитед Средство для снятия похмельного синдрома
RU2558091C2 (ru) * 2013-07-04 2015-07-27 Общество с ограниченной ответственностью "Трейдсервис" Диспергируемая таблетка смектита диоктаэдрического и способ ее получения
WO2018071547A1 (en) * 2016-10-11 2018-04-19 Aucta Pharmaceuticals Powder for oral suspension containing lamotrigine
CN107115304B (zh) * 2017-04-10 2019-02-26 浙江寿仙谷医药股份有限公司 一种去壁灵芝孢子粉片剂及其制备方法
KR102704497B1 (ko) * 2017-12-08 2024-09-10 에프. 호프만-라 로슈 아게 약학 제형

Family Cites Families (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB777516A (en) * 1955-04-14 1957-06-26 Griffiths Hughes Ltd E Improvements in or relating to the production of tablets by pressure
GB837451A (en) * 1956-02-20 1960-06-15 Arner Co Inc Sustained release therapeutic composition and process of preparing same
US3432593A (en) * 1963-09-18 1969-03-11 Key Pharm Inc Delayed and sustained release type pharmaceutical preparation
US3427379A (en) * 1966-01-13 1969-02-11 Hoffmann La Roche Dextromethorphan and benzyl alcohol hard candy lozenges free from opaqueness and/or tiny entrapped air bubbles
US3567819A (en) * 1969-01-30 1971-03-02 Hoffmann La Roche Cold tablet
DE2016622A1 (en) * 1970-04-08 1971-10-21 Farbenfabriken Bayer Ag, 5090 Leverkusen Anthelmintic benzimidazole deriv
CA926708A (en) * 1970-06-15 1973-05-22 Oushima Yoshitaka Process for producing spherical pellets
US4072535A (en) * 1970-12-28 1978-02-07 A. E. Staley Manufacturing Company Precompacted-starch binder-disintegrant-filler material for direct compression tablets and dry dosage capsules
FR2183546B1 (es) * 1972-05-10 1975-06-20 Servier Lab
DE2251249A1 (de) * 1972-10-19 1974-05-02 Hoechst Ag Verfahren zur herstellung von penicillin-verbindungen enthaltenden tabletten
US4209513A (en) * 1974-02-14 1980-06-24 Burroughs Wellcome Co. Tablet formulation
DE2416903A1 (de) * 1974-04-06 1975-10-09 Bayer Ag Verwendung von schmelzverspruehtem kugelfoermigem phenacetingranulat zur herstellung von tabletten im direkttablettierverfahren
JPS5154918A (en) * 1974-10-08 1976-05-14 Nippon Kayaku Kk Jozaino seizoho
GB1533243A (en) * 1975-02-13 1978-11-22 Wellcome Found Tablet formulation
CH630257A5 (en) * 1975-03-17 1982-06-15 Hoffmann La Roche Sustained release formulation
US4086335A (en) * 1975-10-29 1978-04-25 Bruscato Frank N Pharmaceutical tablets containing chitin as a disintegrant
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
GB1567392A (en) * 1977-02-22 1980-05-14 Farmaceutici Italia Daunorubicin derivatives
AU508480B2 (en) * 1977-04-13 1980-03-20 Asahi Kasei Kogyo Kabushiki Kaisha Microcrystalline cellulose excipient and pharmaceutical composition containing thesame
CA1097233A (en) * 1977-07-20 1981-03-10 George K. E. Gregory Packages
GB1601833A (en) * 1978-02-06 1981-11-04 Wellcome Found Antacid formulation
JPS54129129A (en) * 1978-03-30 1979-10-06 Sankyo Co Ltd Powdered pesticide having suppressed static electrification
DE2845326C2 (de) * 1978-10-18 1985-05-23 Beiersdorf Ag, 2000 Hamburg Verwendung einer spezifischen mikrodispersen, amorphen, porösen Kieselsäure zur Herstellung von Digoxin enthaltenden Tabletten mit stark beschleunigter Wirkstoff-Freisetzung
DE2849494A1 (de) * 1978-11-15 1980-05-29 Voss Gunter M Verfahren zur herstellung von arzneimittel-formlingen
CA1112643A (en) * 1979-06-01 1981-11-17 Martin G. Baxter 3,5-diamino-6-phenyl-1,2,4-triazines
US4251518A (en) * 1979-07-03 1981-02-17 Ralston Purina Company Method of preparing readily disintegrable pharmaceutical compositions
JPS56127309A (en) * 1980-03-11 1981-10-06 Dai Ichi Seiyaku Co Ltd Zeolite support for ascorbic acid
JPS5711913A (en) * 1980-06-24 1982-01-21 Tsumura Juntendo Inc Preparation of hard-capsule of herb medicine
JPS5711911A (en) * 1980-06-25 1982-01-21 Tsumura Juntendo Inc Preparation of herb medicine tablet
US4304773A (en) * 1980-06-26 1981-12-08 E. R. Squibb & Sons, Inc. Novel bendroflumethiazide formulations and method
JPS5756434A (en) * 1980-09-22 1982-04-05 Kao Corp Stabilized foamable composition
ATE13486T1 (de) * 1980-11-12 1985-06-15 Ciba Geigy Ag Schnellzerfallende arzneimittel-presslinge.
US4369308A (en) * 1981-07-24 1983-01-18 National Starch And Chemical Corporation Low swelling starches as tablet disintegrants
HU189534B (en) * 1981-09-09 1986-07-28 Chinoin Rt.,Hu Process for producing new tablets containing cyclodextrin polymer as desintegrator
US4414198A (en) * 1982-04-23 1983-11-08 Joseph Michaelson Rapidly disintegrable tablet composition and method
GB2119355B (en) * 1982-04-29 1985-05-09 Scras Modified clays
IL68311A0 (en) * 1982-04-29 1983-07-31 Scras Modified clays,their preparation and pharmaceutical compositions containing them
GR79340B (es) * 1982-07-06 1984-10-22 Sterwin Ag
US4517179A (en) * 1983-04-29 1985-05-14 Pennwalt Corporation Rapid dissolving, uniform drug compositions and their preparation
US4600579A (en) * 1983-06-07 1986-07-15 Mallinckrodt, Inc. N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same
CH658188A5 (de) * 1984-03-23 1986-10-31 Ciba Geigy Ag Lagerstabile schnellzerfallende pharmazeutische presslinge.
US4661521A (en) * 1984-04-30 1987-04-28 Mallinckrodt, Inc. Direct tableting acetaminophen compositions
DE3505433A1 (de) * 1985-02-16 1986-08-21 Basf Ag, 6700 Ludwigshafen Direkttablettierhilfsmittel
US4631305A (en) * 1985-03-22 1986-12-23 The Upjohn Company Polymeric material as a disintegrant in a compressed tablet
EP0199855A1 (en) * 1985-05-02 1986-11-05 Gist-Brocades N.V. Tablets comprising tromethoprim and a sulfonamide
EP0272265B1 (de) * 1985-09-25 1991-05-22 Gergely, Gerhard, Dr. Zerfallstablette und verfahren zu ihrer herstellung
US4781925A (en) * 1986-03-06 1988-11-01 American Home Products Corporation Calcium supplement compressed tablets
JPS62227729A (ja) * 1986-03-31 1987-10-06 Kanegafuchi Chem Ind Co Ltd 断熱材
JPH01501934A (ja) * 1986-04-01 1989-07-06 ジ・アップジョン・カンパニー メチルプレドニソロン／カルボキシメチルスターチナトリウム錠剤組成物
GB8613183D0 (en) * 1986-05-30 1986-07-02 Wellcome Found Triazine salt
DE3635864A1 (de) * 1986-06-26 1988-05-05 Gerhard Gergely Verfahren zum herstellen eines brausegranulates, danach hergestelltes brausegranulat sowie dessen verwendung
US4757090A (en) * 1986-07-14 1988-07-12 Mallinckrodt, Inc. Direct tableting acetaminophen compositions
KR960001372B1 (ko) * 1986-09-24 1996-01-26 예일 유니버시티 레트로비루스로 감염된 환자의 치료에 사용되는 2',3'-디디옥시사이티딘-2'-엔(2',3'-디디옥시-2',3'-디디하이드로사이티딘)의 항생물질
GB8624628D0 (en) * 1986-10-14 1986-11-19 Scras Soluble/splitable tablets
US4771077A (en) * 1986-10-21 1988-09-13 American Home Products Corporation (Del.) Spray dried acetaminophen
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
DE3887179T2 (de) * 1987-03-02 1994-06-16 Brocades Pharma Bv Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.
EP0294933B1 (en) * 1987-05-08 1992-03-11 Smith Kline & French Laboratories Limited Pharmaceutical compositions
US4904477A (en) * 1987-07-08 1990-02-27 American Home Products Corporation Spray dried ibuprofen compositions
ES2026198T3 (es) * 1987-07-22 1992-04-16 Farvalsa Ag Compuesto a base de acido valproico solido, estable a la humedad y metodo para su preparacion.
JP2527973B2 (ja) * 1987-08-05 1996-08-28 株式会社資生堂 球状粘土鉱物及びその製造方法
DE3806633A1 (de) * 1987-09-01 1989-03-09 Bayer Ag Antivirales mittel
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
JP2537062B2 (ja) * 1987-10-02 1996-09-25 株式会社資生堂 薬剤組成物
US4999200A (en) * 1987-12-09 1991-03-12 Marion Laboratories Psyllium tablet composition, method of manufacture and method of use
ATE108996T1 (de) * 1988-02-25 1994-08-15 Brocades Pharma Bv Verfahren zur herstellung eines pharmazeutischen granulats.
US4910023A (en) * 1988-06-09 1990-03-20 Warner-Lambert Company Drug in combination with flavor masking agent and method for making same
YU120988A (en) * 1988-06-23 1990-06-30 Lek Tovarna Farmacevtskih Process for preparing new dispersion pills of cimetidine
IT1226549B (it) * 1988-07-12 1991-01-24 Resa Farma Composizioni farmaceutiche ad attivita' analgesica ed antiinfiammatoria per uso orale, dotate di ottima palatabilita' ed esenti da effetti irritanti sulle mucose.
YU183988A (en) * 1988-09-30 1990-08-31 Lek Tovarna Farmacevtskih Process for preparing dispersion pills of dihydroergotoxine
JPH02111620A (ja) * 1988-10-21 1990-04-24 Kunimine Kogyo Kk 水中分散性粒剤
US5073377A (en) * 1988-11-03 1991-12-17 Miles Inc. Method of preparing oral dosage forms with a granulating composition
US4965072A (en) * 1988-11-03 1990-10-23 Miles Inc. Granulating composition and method
JPH02145501A (ja) * 1988-11-25 1990-06-05 Sanyo Chem Ind Ltd 殺生剤粒剤組成物
FI895821A0 (fi) * 1988-12-07 1989-12-05 Wellcome Found Farmaceutiskt aktiva cns foereningar.
US4927639A (en) * 1989-02-02 1990-05-22 Warner-Lambert Company Modified release gemfibrozil composition
US4925676A (en) * 1989-02-02 1990-05-15 Warner-Lambert Company Extended release gemfibrozil composition
ATE107469T1 (de) * 1989-04-07 1994-07-15 Ciba Geigy Ag Pestizide wirkstoffkonzentrate und ihre herstellung.
US4970078A (en) * 1989-05-25 1990-11-13 Aqualon Company Crosslinked carboxymethyguar tablet disintegrant
DK0490920T3 (da) * 1989-09-07 1994-04-25 Gerhard Gergely Mavesyrebindende farmaceutisk præparat
US5037658A (en) * 1989-09-14 1991-08-06 Hoechst-Roussel Pharmaceuticals, Inc. Direct dry compressible acetaminophen composition
US5064656A (en) * 1989-11-14 1991-11-12 Dr. Gergely & Co. Uncoated pharmaceutical reaction tablet
US5136080A (en) * 1989-12-04 1992-08-04 Burroughs Wellcome Co. Nitrile compounds
JP3069665B2 (ja) * 1990-03-15 2000-07-24 住友化学工業株式会社 農業用粒状水和剤組成物
GB9012311D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
GB9012316D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
US5087454A (en) * 1990-07-30 1992-02-11 American Home Products Corporation Ibuprofen tablet
GB9025372D0 (en) * 1990-11-22 1991-01-09 Nat Res Dev Pharmaceutical dosage forms

Also Published As

Publication number Publication date
EP0522128B1 (en) 1996-01-17
SK81793A3 (en) 1994-03-09
NO306697B1 (no) 1999-12-13
FR2671970B1 (fr) 1995-06-23
FI933401A (fi) 1993-07-29
MY110880A (en) 1999-06-30
ITRM920069A1 (it) 1993-07-30
CH685978A5 (fr) 1995-11-30
IL100796A (en) 1998-09-24
IE920284A1 (en) 1992-07-29
UA37214C2 (uk) 2001-05-15
MY120025A (en) 2005-08-30
FI933401A0 (fi) 1993-07-29
ATE133068T1 (de) 1996-02-15
HU221677B1 (hu) 2002-12-28
HUT67019A (en) 1995-01-30
FI111605B (fi) 2003-08-29
KR100190254B1 (ko) 1999-06-01
JP3118255B2 (ja) 2000-12-18
NL9220009A (nl) 1993-11-01
SK282072B6 (sk) 2001-10-08
BG61665B2 (bg) 1998-02-27
NO932422D0 (no) 1993-07-02
RU2106861C1 (ru) 1998-03-20
PA7695401A1 (es) 1996-05-20
IT1257473B (it) 1996-01-25
MX9200412A (es) 1992-09-01
SK282071B6 (sk) 2001-10-08
KR930702959A (ko) 1993-11-29
LU88323A1 (fr) 1994-01-05
US5660860A (en) 1997-08-26
NO932422L (no) 1993-07-02
US5556639A (en) 1996-09-17
GB9218097D0 (en) 1992-11-04
EP0522128A1 (en) 1993-01-13
HK78597A (en) 1997-06-20
JPH06504544A (ja) 1994-05-26
IE77165B1 (en) 1997-12-03
DE4290300T1 (de) 1993-10-07
DK0522128T3 (da) 1996-02-26
AU6745494A (en) 1994-09-08
CZ286723B6 (cs) 2000-06-14
DE69207656D1 (de) 1996-02-29
DK87893A (da) 1993-07-27
JP3483515B2 (ja) 2004-01-06
SE9302363L (sv) 1993-07-08
JP2000273045A (ja) 2000-10-03
IL100796A0 (en) 1992-09-06
GB2257363B (en) 1994-09-28
FR2671970A1 (fr) 1992-07-31
ES2080641B1 (es) 1996-11-01
FI20021701A (fi) 2002-09-24
GB2257363A (en) 1993-01-13
PL169106B1 (pl) 1996-06-28
AU653203B2 (en) 1994-09-22
SA92120365B1 (ar) 2004-03-20
HU9302212D0 (en) 1993-10-28
GR3019545T3 (en) 1996-07-31
DK87893D0 (da) 1993-07-27
CZ108293A3 (en) 1994-01-19
ITRM920069A0 (it) 1992-01-30
BE1004461A5 (fr) 1992-11-24
ES2080641A1 (es) 1996-02-01
SE9302363D0 (sv) 1993-07-08
AU1186392A (en) 1992-09-07
WO1992013527A1 (en) 1992-08-20
CA2098108C (en) 2001-07-03
CY2007A (en) 1998-02-20
DE69207656T2 (de) 1996-10-17
CA2098108A1 (en) 1992-07-31
HU211161A9 (en) 1995-10-30
AU659581B2 (en) 1995-05-18

Similar Documents

Publication Publication Date Title
ES2089498T3 (es) Comprimidos dispersables en agua.
ES2119219T3 (es) Cierres estancos para uso en un dispositivo para suministrar un aerosol.
GR3026338T3 (en) High release solid preparation, preparation and use thereof
BR9811927A (pt) Dispositivo de liberação de agente benéfico propelido por gás que pode ser implantado
ES2028427T3 (es) Procedimiento para combatir insectos.
ES2152242T3 (es) Agentes de control de la espuma basados en organopolisiloxanos.
CA2165292A1 (en) Absorbent Core Having Improved Fluid Handling Properties
FI953490A0 (fi) Kuidut
ES2139877T3 (es) Agente anti-incrustacion.
GB2328161A (en) Synchronising of animal oestrus and intra vaginal devices useful therein
ES278992U (es) Un dispositivo para la distribucion de vapores de tratamiento del aire
SE9203294L (sv) Fjädermutteranordning
ES2092201T3 (es) Dispositivo de frenado particularmente para patines.
MX9205993A (es) Electrodo de evolucion de gas de porosidad doble
ES2101923T3 (es) Lentes de coloracion fija neutra absorbentes de rayos ultravioleta.
ES2124568T3 (es) Aparato de fluidizacion.
CA2063127A1 (en) Reduction in cutaneous atrophy
NO934672L (no) Anordning egnet for intrauterin anvendelse
ES2132203T3 (es) Gel descontaminante reductor para descontaminacion de superficies.
CN208872178U (zh) 多用警盾
GB826062A (en) Improvements in lock nuts
MX9408958A (es) Uso, composicion y metodo de benzoilureas para controlar acaros de polvo domestico.
van Haeringen Charged‐particle off‐shell scattering: common structure of all two‐body off‐shell scattering quantities for Coulomb plus rational separable potentials
AU569101B2 (en) Sachet with anti-crushing device
Agishev et al. Continuous-wave IR lidar for the remote monitoring of natural gas leaks

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 522128

Country of ref document: ES

FG2A Definitive protection

Ref document number: 522128

Country of ref document: ES