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ES2063309T3 - Derivados de pirimidina 3-oxido halogenados, su utilizacion para el tratamiento y la prevencion de la caida de los cabellos y para estimular su crecimiento. - Google Patents

Derivados de pirimidina 3-oxido halogenados, su utilizacion para el tratamiento y la prevencion de la caida de los cabellos y para estimular su crecimiento.

Info

Publication number
ES2063309T3
ES2063309T3 ES90401983T ES90401983T ES2063309T3 ES 2063309 T3 ES2063309 T3 ES 2063309T3 ES 90401983 T ES90401983 T ES 90401983T ES 90401983 T ES90401983 T ES 90401983T ES 2063309 T3 ES2063309 T3 ES 2063309T3
Authority
ES
Spain
Prior art keywords
prevention
treatment
formula
image
pyrimidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90401983T
Other languages
English (en)
Inventor
Remy Tuloup
Alex Junino
Michel Hocquaux
Jacqueline Dumats
Quintino Gaetani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP89402002A external-priority patent/EP0356271B1/fr
Priority claimed from FR9001148A external-priority patent/FR2657609B1/fr
Application filed by LOreal SA filed Critical LOreal SA
Application granted granted Critical
Publication of ES2063309T3 publication Critical patent/ES2063309T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION SE RELACIONA CON COMPUESTOS DE FORMULA (I), EN LA QUE R1 Y R2 DESIGNAN, INDEPENDIENTEMENTE UNO DEL OTRO, UN ATOMO DE HIDROGENO O UN GRUPO CARBAMOILO DE FORMULA (B), DONDE R3'' DESIGNA HIDROGENO O R3; UN GRUPO ALCOXICARBONILO DE FORMUAL (C) O UN GRUPO ACILO DE FORMULA (D), EN LAS QUE R3 DESIGNA UN RADICAL ALQUILO, ALQUENILO, CICLOALQUILO; R3 PUEDE DESIGNAR IGUALMENTE UN RADICAL ARILO O ARILALQUILO; R DESIGNA UN RADICAL ALQUILO, LINEAL O RAMIFICADO C1-C6, SUSTITUIDO POR UNO O VARIOS ATOMOS DE HALOGENO, Y A SU USO PARA EL TRATAMIENTO Y LA PREVENCION DE LA CAIDA DE LOS CABELLOS Y PARA ESTIMULAR SU REBROTE.
ES90401983T 1989-07-12 1990-07-10 Derivados de pirimidina 3-oxido halogenados, su utilizacion para el tratamiento y la prevencion de la caida de los cabellos y para estimular su crecimiento. Expired - Lifetime ES2063309T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP89402002A EP0356271B1 (fr) 1988-08-01 1989-07-12 Nouveaux dérivés de diamino-2,4 pyrimidine oxyde-3 et leur utilisation pour le traitement et la prévention de la chute des cheveux
FR9001148A FR2657609B1 (fr) 1990-01-31 1990-01-31 Nouveaux derives de pyrimidine oxyde-3 halogenes, leur utilisation pour le traitement et la prevention de la chute des cheveux et pour stimuler leur repousse.

Publications (1)

Publication Number Publication Date
ES2063309T3 true ES2063309T3 (es) 1995-01-01

Family

ID=26123150

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90401983T Expired - Lifetime ES2063309T3 (es) 1989-07-12 1990-07-10 Derivados de pirimidina 3-oxido halogenados, su utilizacion para el tratamiento y la prevencion de la caida de los cabellos y para estimular su crecimiento.

Country Status (7)

Country Link
US (1) US5132106A (es)
EP (1) EP0408442B1 (es)
JP (1) JPH03115270A (es)
AT (1) ATE110718T1 (es)
CA (1) CA2020986A1 (es)
DE (1) DE69012010T2 (es)
ES (1) ES2063309T3 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2678929A1 (fr) * 1991-07-11 1993-01-15 Oreal Compositions pour freiner la chute des cheveux et pour induire et stimuler leur croissance a base de derives de 2,4-diamino pyrimidine 3-oxyde, nouveaux derives 2,4-diamino pyrimidine 3-oxyde.
AU680818B2 (en) * 1992-05-21 1997-08-14 Endorecherche Inc. Improved antiandrogens
US5451407A (en) * 1993-06-21 1995-09-19 Alza Corporation Reduction or prevention of skin irritation or sensitization during transdermal administration of a irritating or sensitizing drug
FR2732597B1 (fr) * 1995-04-05 1997-05-16 Oreal Utilisation dans une composition en tant qu'activateur et/ou stabilisateur de cyclooxygenase d'au moins un derive de pyrimidine substitue en 6
US6541479B1 (en) * 1997-12-02 2003-04-01 Massachusetts College Of Pharmacy Calcium channel blockers
DE19805432C1 (de) * 1998-02-11 1999-03-04 Wella Ag Haarbehandlungsmittel mit fluorierten Aminen und Polymeren
JP2002506104A (ja) 1998-03-11 2002-02-26 ザ ダウ ケミカル カンパニー エンジニアリング熱可塑性樹脂とブレンドされたアルファ−オレフィンモノマーと１以上のビニルまたはビニリデン芳香族モノマーおよび／又は１以上のヒンダード脂肪族または脂環式ビニルまたはビニリデンモノマーのインターポリマーの熱可塑性組成物
DE19845202A1 (de) * 1998-10-01 2000-04-06 Wella Ag Haarwuchsmittel
US6159950A (en) * 1998-10-16 2000-12-12 Cornell Research Foundation, Inc. Method of modulating hair growth
FR2791671B1 (fr) 1999-04-01 2001-05-11 Oreal Nouveaux composes derives d'esters d'acide benzoique, composition les comprenant et utilisation
CN1662229B (zh) 2002-06-21 2010-05-26 奥里尔股份有限公司 牛磺酸和/或亚牛磺酸在制备治疗秃头症的药物中的应用
EP1442753B1 (en) * 2003-02-03 2007-02-21 Polaschegg, Hans-Dietrich, Dr.techn. Composition for the prevention of indwelling device related infection
US7326717B2 (en) 2003-05-06 2008-02-05 L'oreal Pyrimidine n-oxide compounds for stimulating the growth of keratin fibers and/or reducing loss thereof
FR2854630B1 (fr) * 2003-05-06 2005-06-10 Oreal Composition capilaire contenant un derive de pyrimidine n-oxydase, son utilisation pour stimuler la pousse des fibres keratiniques et/ou freiner leur chute
FR2920309B1 (fr) 2007-08-28 2010-05-28 Galderma Res & Dev Utilisation de travoprost pour traiter la chute des cheveux
US8551463B2 (en) 2007-10-22 2013-10-08 Living Proof, Inc. Hair care compositions and methods of treating hair
KR100963736B1 (ko) * 2008-07-10 2010-06-14 김근태 신발끈 제조방법
FR2953722B1 (fr) 2009-12-16 2012-03-09 Expanscience Lab Composition comprenant au moins un sucre en c7 pour le traitement de l'alopecie, pour le traitement cosmetique des phaneres, et pour le soin des cheveux, cils ou ongles
AU2014361754B2 (en) 2013-12-12 2020-04-30 Cellmid Limited Method of treatment of alopecia with monoterpenoids
EP3895685A1 (en) 2020-04-14 2021-10-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Natural composition for hair growth stimulation and hair loss prevention and treatment without preservatives
EP3895686A1 (en) 2020-04-14 2021-10-20 FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. Natural composition for hair growth stimulation and hair loss prevention and treatment

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000616A1 (en) * 1984-07-13 1986-01-30 Gail Sansone Bazzano Substituted pyrimidine oxides useful for hair growth promotion
DE3717480A1 (de) * 1987-05-23 1988-12-01 Shell Agrar Gmbh & Co Kg Neue herbizid und mikrobizid wirksame 2,6-diaminopyrimidine
LU87308A1 (fr) * 1988-08-01 1990-03-13 Oreal Nouveaux derives de diamino-2,4 pyrimidine oxyde-3 et leur utilisation pour le traitement et la prevention de la chute des cheveux

Also Published As

Publication number Publication date
CA2020986A1 (fr) 1991-01-13
EP0408442A1 (fr) 1991-01-16
ATE110718T1 (de) 1994-09-15
US5132106A (en) 1992-07-21
EP0408442B1 (fr) 1994-08-31
DE69012010T2 (de) 1995-04-13
DE69012010D1 (de) 1994-10-06
JPH03115270A (ja) 1991-05-16

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