ES2061896T3 - Procedimiento para la preparacion de bencimidazolonas. - Google Patents
Procedimiento para la preparacion de bencimidazolonas.Info
- Publication number
- ES2061896T3 ES2061896T3 ES89121485T ES89121485T ES2061896T3 ES 2061896 T3 ES2061896 T3 ES 2061896T3 ES 89121485 T ES89121485 T ES 89121485T ES 89121485 T ES89121485 T ES 89121485T ES 2061896 T3 ES2061896 T3 ES 2061896T3
- Authority
- ES
- Spain
- Prior art keywords
- bencimidazolones
- procedure
- preparation
- formula
- trifluormetilo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000004985 diamines Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical class O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
EL INVENTO SE REFIERE A UN PROCEDIMIENTO PARA PRODUCIR BENCIMIDAZOLONAS DE FORMULA (1) QUE CONSISTE EN TRATAR UN O-FENILENODIAMINA DE FORMULA (2) CON FOSGENO EN AGUA EN PRESENCIA DE UNAS SALES ALCALINAS O ALCALINOTERREAS O DE UNAS SALES DE UN HIDROXIDO ALCALINO O ALCALINOTERREO Y UN ACIDO ORGANICO O INORGANICO DEBIL, EN UN SISTEMA TAMPON CON UN PH ENTRE 8 Y 12 Y A UNA TEMPERATURA ENTRE 20 Y 100 C. SIENDO: R1 Y R2 IGUALES O DIFERENTES, HIDROGENO, HALOGENO, ALQUILO DE C 1 A 4, ALCOXI DE C 1 A 4, TRIFLUORMETILO, FENILO, FENOXI O GRUPO NITRO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3839743A DE3839743A1 (de) | 1988-11-25 | 1988-11-25 | Verfahren zur herstellung von benzimidazolonen |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2061896T3 true ES2061896T3 (es) | 1994-12-16 |
Family
ID=6367834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89121485T Expired - Lifetime ES2061896T3 (es) | 1988-11-25 | 1989-11-21 | Procedimiento para la preparacion de bencimidazolonas. |
Country Status (6)
Country | Link |
---|---|
US (1) | US5003079A (es) |
EP (1) | EP0370448B1 (es) |
JP (1) | JPH02193981A (es) |
CA (1) | CA2003770A1 (es) |
DE (2) | DE3839743A1 (es) |
ES (1) | ES2061896T3 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6297236B1 (en) | 1998-04-06 | 2001-10-02 | Bayer Aktiengesellschaft | Fungicide active substance combinations |
CN1177831C (zh) | 1998-12-04 | 2004-12-01 | 神经研究公司 | 作为离子通道调节剂的新的苯并咪唑啉酮一、苯并噁唑酮一或苯并噻唑啉酮衍生物 |
GB0008939D0 (en) * | 2000-04-11 | 2000-05-31 | Glaxo Group Ltd | Process for preparing substituted benzimidazole compounds |
CN103052681B (zh) | 2010-08-02 | 2015-11-25 | 汉高股份有限及两合公司 | 用于环氧树脂的固化剂 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2933503A (en) * | 1957-01-14 | 1960-04-19 | Merck & Co Inc | Benzimidazole derivatives |
NZ187066A (en) * | 1977-05-03 | 1981-02-11 | Hoffmann La Roche | 4-(3-substitutedamino-2-hydroxypropoxy)-benzimidazolidin-2-(ones or thiones) |
DE2855226A1 (de) * | 1978-12-21 | 1980-07-10 | Hoechst Ag | Verfahren zur herstellung von benzimidazolon-(2) |
DE2905876A1 (de) * | 1979-02-16 | 1980-08-28 | Boehringer Mannheim Gmbh | Neue piperidinopropylderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
US4374250A (en) * | 1980-06-23 | 1983-02-15 | Osaka Municipal Government | Method of producing benzimidazolone |
FR2485012A1 (fr) * | 1980-06-23 | 1981-12-24 | Osaka Municipal Government | Procede pour la fabrication de benzimidazolones |
DD155616A1 (de) * | 1980-12-23 | 1982-06-23 | Wilfried Schulze | Verfahren zur herstellung von 1-chlorcarbonyl-benzimidazol-2-onen |
JPS5940391B2 (ja) * | 1981-02-12 | 1984-09-29 | 大阪市 | ベンツイミダゾロン、ベンツオキサゾロン又はベンツチアゾロンの製造方法 |
-
1988
- 1988-11-25 DE DE3839743A patent/DE3839743A1/de not_active Withdrawn
-
1989
- 1989-11-21 DE DE89121485T patent/DE58907177D1/de not_active Expired - Fee Related
- 1989-11-21 EP EP89121485A patent/EP0370448B1/de not_active Expired - Lifetime
- 1989-11-21 ES ES89121485T patent/ES2061896T3/es not_active Expired - Lifetime
- 1989-11-22 JP JP1302270A patent/JPH02193981A/ja active Pending
- 1989-11-24 CA CA002003770A patent/CA2003770A1/en not_active Abandoned
- 1989-11-24 US US07/441,160 patent/US5003079A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2003770A1 (en) | 1990-05-25 |
EP0370448B1 (de) | 1994-03-09 |
DE58907177D1 (de) | 1994-04-14 |
JPH02193981A (ja) | 1990-07-31 |
EP0370448A1 (de) | 1990-05-30 |
US5003079A (en) | 1991-03-26 |
DE3839743A1 (de) | 1990-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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