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ES2055104T3 - Un procedimiento para preparar un compuesto que tiene actividad antagonista de fap. - Google Patents

Un procedimiento para preparar un compuesto que tiene actividad antagonista de fap.

Info

Publication number
ES2055104T3
ES2055104T3 ES89312361T ES89312361T ES2055104T3 ES 2055104 T3 ES2055104 T3 ES 2055104T3 ES 89312361 T ES89312361 T ES 89312361T ES 89312361 T ES89312361 T ES 89312361T ES 2055104 T3 ES2055104 T3 ES 2055104T3
Authority
ES
Spain
Prior art keywords
fap
preparing
procedure
compound
antagonist activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89312361T
Other languages
English (en)
Inventor
Aiya Sato
Michihiro Sugano
Kouhei Furuya
Takeshi Oshima
Harumitsu Kuwano
Tadashi Hata
Hideyuki Haruyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of ES2055104T3 publication Critical patent/ES2055104T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

SE PRESENTAN UNA SERIE DE NUEVOS COMPUESTOS, LLAMADOS "PHOMACTINS" QUE PUEDEN SER AISLADOS DEL CALDO DE CULTIVO DE HONGOS DEL GENERO "PHOMA" ESPECIALMENTE "PHOMA SP." SANK 11486 (NO. FERM BP-2598). ESTOS COMPUESTOS SON ANTAGONISTAS DE FACTOR ACTIVADOR Y PUEDEN USARSE EN EL TRATAMIENTO DE ENFERMEDADES PARA LAS CUALES LOS AGENTES CONOCIDOS PUEDEN TAMBIEN USARSE.
ES89312361T 1988-11-28 1989-11-28 Un procedimiento para preparar un compuesto que tiene actividad antagonista de fap. Expired - Lifetime ES2055104T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP30027888 1988-11-28

Publications (1)

Publication Number Publication Date
ES2055104T3 true ES2055104T3 (es) 1994-08-16

Family

ID=17882866

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89312361T Expired - Lifetime ES2055104T3 (es) 1988-11-28 1989-11-28 Un procedimiento para preparar un compuesto que tiene actividad antagonista de fap.

Country Status (7)

Country Link
US (1) US5151529A (es)
EP (1) EP0371762B1 (es)
KR (1) KR940004128B1 (es)
AT (1) ATE88707T1 (es)
CA (1) CA2003956A1 (es)
DE (1) DE68906248T2 (es)
ES (1) ES2055104T3 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2227369A1 (en) * 1995-07-25 1997-02-13 Fernando Pelaez Inhibitors of farnesyl-protein transferase
US5663193A (en) * 1995-07-25 1997-09-02 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
JP4123106B2 (ja) 2003-08-22 2008-07-23 ソニー株式会社 有機ｅｌ素子

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6339591A (ja) * 1986-08-04 1988-02-20 Nippon Kayaku Co Ltd 新規生理活性物質ＮＫ−Ａ−１７−ｅ−２３３およびその製造法
JPS63307872A (ja) * 1987-06-09 1988-12-15 Nippon Kayaku Co Ltd 新規生理活性物質ＮＫ−Ａ−１７−ｅ−２３３−４およびその製造法

Also Published As

Publication number Publication date
KR940004128B1 (ko) 1994-05-13
DE68906248T2 (de) 1993-08-12
KR900008048A (ko) 1990-06-02
DE68906248D1 (de) 1993-06-03
US5151529A (en) 1992-09-29
EP0371762A2 (en) 1990-06-06
CA2003956A1 (en) 1990-05-28
EP0371762B1 (en) 1993-04-28
EP0371762A3 (en) 1991-03-20
ATE88707T1 (de) 1993-05-15

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