ES2044976T3 - Preparados activos frente a infecciones por pseudomonas aeruginosa y procedimiento para su fabricacion. - Google Patents
Preparados activos frente a infecciones por pseudomonas aeruginosa y procedimiento para su fabricacion.Info
- Publication number
- ES2044976T3 ES2044976T3 ES87890135T ES87890135T ES2044976T3 ES 2044976 T3 ES2044976 T3 ES 2044976T3 ES 87890135 T ES87890135 T ES 87890135T ES 87890135 T ES87890135 T ES 87890135T ES 2044976 T3 ES2044976 T3 ES 2044976T3
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- flagelar
- vaccines
- preparations
- aeruginous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000002360 preparation method Methods 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 208000032536 Pseudomonas Infections Diseases 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229960005486 vaccine Drugs 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 239000000178 monomer Substances 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 241000589516 Pseudomonas Species 0.000 abstract 1
- 238000001042 affinity chromatography Methods 0.000 abstract 1
- 150000001413 amino acids Chemical group 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 229940027941 immunoglobulin g Drugs 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 210000002381 plasma Anatomy 0.000 abstract 1
- 230000001012 protector Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Vessels, Lead-In Wires, Accessory Apparatuses For Cathode-Ray Tubes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
SE DESCRIBEN PREPARACIONES ACTIVAS CONTRA LAS INFECCIONES PRODUCIDAS POR LA PSEUDOMONA AERUGINOSA, ES DECIR VACUNAS PARA LA INMUNIZACION ACTIVA Y PREPARACIONES DESTINADAS A LA PROTECCION PASIVA QUE CONTIENEN ANTICUERPOS, Y PROCEDIMIENTO PARA SU PREPARACION. LAS VACUNAS CONTIENEN ANTIGENO H FLAGELAR PROTECTOR DEL SEROTIPO-H A Y B, QUE CONSISTEN EN COMPONENTES MONOMEROS, ESTANDO CONSTITUIDO CADA UNO DE LOS COMPONENTES MONOMEROS POR AMINOACIDOS DETERMINADOS CON UNA SECUENCIA DE AMINOACIDOS N-TERMINAL Y PRESENTANDO UN PESO MOLECULAR DETERMINADO. LAS VACUNAS SE PREPARAN A PARTIR DE SOLUCIONES PURAS DE ANTIGENO H FLAGELAR. LAS PREPARACIONES QUE CONTIENEN INMUNOGLOBULINA G CONTIENEN ANTICUERPOS H FLAGELARES OBTENIDOS DEL PLASMA SANGUINEO DE DONANTES HUMANOS INMUNIZADOS O DE ANIMALES MAMIFEROS INMUNIZADOS. AQUELLAS PUEDEN PURIFICARSE POR UN PROCEDIMIENTO DE CROMATOGRAFIA DE AFINIDAD.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT1716/86A AT391080B (de) | 1986-06-24 | 1986-06-24 | Verfahren zur herstellung von gegen pseudomonas aeruginosa infektionen wirksamen praeparationen |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2044976T3 true ES2044976T3 (es) | 1994-01-16 |
Family
ID=3519452
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES87890135T Expired - Lifetime ES2044976T3 (es) | 1986-06-24 | 1987-06-15 | Preparados activos frente a infecciones por pseudomonas aeruginosa y procedimiento para su fabricacion. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4946677A (es) |
EP (1) | EP0252064B1 (es) |
JP (2) | JPH0830011B2 (es) |
AT (2) | AT391080B (es) |
CA (1) | CA1306690C (es) |
DE (1) | DE3782771D1 (es) |
DK (1) | DK173123B1 (es) |
ES (1) | ES2044976T3 (es) |
FI (1) | FI86508C (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5237053A (en) * | 1986-06-24 | 1993-08-17 | Immuno Aktiengesellschaft | Preparation active against Pseudomonas aeruginosa infections and methods of producing them |
AT390192B (de) * | 1988-08-29 | 1990-03-26 | Immuno Ag | Gegen pseudomonas aeruginosa-infektionen wirksame praeparationen sowie immunglobuling-h|ltige, gegen bakterium pseudomonas aeruginosa wirksame praeparationen |
AU5405794A (en) * | 1992-10-16 | 1994-05-09 | Brigham And Women's Hospital | O-derivatized alginic acid antigens |
GB9701489D0 (en) | 1997-01-24 | 1997-03-12 | Auspharm Int Ltd | Antigen |
US6749831B1 (en) * | 1997-05-16 | 2004-06-15 | Medical Defense Technology, Llc | Vaccine against lipopolysaccharide core |
US7405039B2 (en) | 2002-02-07 | 2008-07-29 | Austin Health | Viral variants with altered susceptibility to nucleoside analogs and uses thereof |
EP1499712A4 (en) | 2002-04-12 | 2008-04-16 | Melbourne Health | HEPATITIS B VIRUS VARIANTS WITH REDUCED SENSITIVITY TO NUCLEOSIDANALOGES AND USE THEREOF |
JP2007530029A (ja) * | 2004-03-26 | 2007-11-01 | クアーク・ファーマスーティカルス、インコーポレイテッド | アネキシンii及びその使用 |
EP1874923A4 (en) | 2005-04-08 | 2010-08-04 | Melbourne Health | VARIANTS OF THE HEPATITIS B VIRUS WITH RESISTANCE TO ANTIVIRAL NUCLEOSIDAGENTS AND APPLICATIONS THEREOF |
US8211443B2 (en) | 2005-04-08 | 2012-07-03 | Melbourne Health | Variants of hepatitis B virus with resistance to anti-viral nucleoside agents and applications thereof |
US8263078B2 (en) | 2007-09-05 | 2012-09-11 | Inotek Pharmaceuticals Corporation | Antibodies against flagellin and uses thereof |
US20100239583A1 (en) * | 2009-03-04 | 2010-09-23 | Inotek Pharmaceuticals Corporation | Antibodies against flagellin and uses thereof |
WO2011046504A1 (en) * | 2009-10-18 | 2011-04-21 | Glycorex Ab | Method and product for blood treatment and purification |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3674863A (en) * | 1969-12-08 | 1972-07-04 | Parke Davis & Co | Polyvalent immunizing agents and methods for their production |
US3987164A (en) * | 1970-10-20 | 1976-10-19 | Yuzuru Homma | Method for prevention of pseudomonas aeruginosa infections |
US3928565A (en) * | 1971-10-19 | 1975-12-23 | Yuzuru Homma | Pharmaceutical preparation of pseudomonas aeruginosa bacterial component possessing anti-tumor and anti-infection properties |
FR2227861B1 (es) * | 1973-05-04 | 1976-07-02 | Anvar | |
US4075321A (en) * | 1973-05-04 | 1978-02-21 | Agence Nationale De Valorisation De La Recherche (Anvar) | Vaccines, the process for preparing the same and the applications thereof |
JPS51133489A (en) * | 1975-05-14 | 1976-11-19 | Tokyo Daigaku | Process for producing microbial components of pseudomonas aeruginosa h aving antimicrobial and antitumor activities |
US4298597A (en) * | 1979-09-04 | 1981-11-03 | University Of Saskatchewan | Vaccine for diarrhea caused by E. coli |
JPS60248625A (ja) * | 1984-05-25 | 1985-12-09 | Mitsui Toatsu Chem Inc | 抗緑膿菌モノクロ−ナル抗体、その製法ならびに用途 |
AT384032B (de) * | 1985-01-14 | 1987-09-25 | Immuno Ag | Verfahren zur herstellung von polydispersen nativen pseudomonas-flagella(h)-antigenen (fag) |
US4693891A (en) * | 1985-09-09 | 1987-09-15 | Miles Laboratories, Inc. | Vaccine for Pseudomonas aeruginosa |
FR2597344B1 (fr) * | 1986-04-16 | 1989-06-23 | Merieux Inst | Perfectionnement au procede de purification d'antigenes proteiques de bacteries appartenant au genre bordetella, en vue de l'obtention d'un vaccin acellulaire. |
-
1986
- 1986-06-24 AT AT1716/86A patent/AT391080B/de active
-
1987
- 1987-06-09 CA CA000539163A patent/CA1306690C/en not_active Expired - Lifetime
- 1987-06-15 EP EP87890135A patent/EP0252064B1/de not_active Expired - Lifetime
- 1987-06-15 DE DE8787890135T patent/DE3782771D1/de not_active Expired - Fee Related
- 1987-06-15 AT AT87890135T patent/ATE82687T1/de not_active IP Right Cessation
- 1987-06-15 ES ES87890135T patent/ES2044976T3/es not_active Expired - Lifetime
- 1987-06-17 US US07/063,094 patent/US4946677A/en not_active Expired - Lifetime
- 1987-06-22 FI FI872750A patent/FI86508C/fi not_active IP Right Cessation
- 1987-06-24 DK DK198703222A patent/DK173123B1/da not_active IP Right Cessation
- 1987-06-24 JP JP62157475A patent/JPH0830011B2/ja not_active Expired - Fee Related
-
1995
- 1995-08-21 JP JP7211624A patent/JP2534470B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATA171686A (de) | 1990-02-15 |
FI86508B (fi) | 1992-05-29 |
EP0252064A3 (en) | 1989-03-15 |
JP2534470B2 (ja) | 1996-09-18 |
DK173123B1 (da) | 2000-01-31 |
DK322287D0 (da) | 1987-06-24 |
JPH0853367A (ja) | 1996-02-27 |
CA1306690C (en) | 1992-08-25 |
AT391080B (de) | 1990-08-10 |
ATE82687T1 (de) | 1992-12-15 |
FI872750A (fi) | 1987-12-25 |
EP0252064B1 (de) | 1992-11-25 |
FI86508C (fi) | 1992-09-10 |
JPS635029A (ja) | 1988-01-11 |
FI872750A0 (fi) | 1987-06-22 |
US4946677A (en) | 1990-08-07 |
EP0252064A2 (de) | 1988-01-07 |
DK322287A (da) | 1987-12-25 |
JPH0830011B2 (ja) | 1996-03-27 |
DE3782771D1 (de) | 1993-01-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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