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EP4312575A1 - Mit palmitinsäure angereichertes festes avocadoöl - Google Patents

Mit palmitinsäure angereichertes festes avocadoöl

Info

Publication number
EP4312575A1
EP4312575A1 EP22717404.2A EP22717404A EP4312575A1 EP 4312575 A1 EP4312575 A1 EP 4312575A1 EP 22717404 A EP22717404 A EP 22717404A EP 4312575 A1 EP4312575 A1 EP 4312575A1
Authority
EP
European Patent Office
Prior art keywords
avocado
concrete
oil
avocado oil
oils
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP22717404.2A
Other languages
English (en)
French (fr)
Inventor
Antoine Piccirilli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Greentech SA
Original Assignee
Greentech SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Greentech SA filed Critical Greentech SA
Publication of EP4312575A1 publication Critical patent/EP4312575A1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
    • A23D9/02—Other edible oils or fats, e.g. shortenings or cooking oils characterised by the production or working-up
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
    • A23D9/02—Other edible oils or fats, e.g. shortenings or cooking oils characterised by the production or working-up
    • A23D9/04—Working-up
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G1/00—Cocoa; Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/30—Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/32—Cocoa products, e.g. chocolate; Substitutes therefor characterised by the composition containing organic or inorganic compounds
    • A23G1/36—Cocoa products, e.g. chocolate; Substitutes therefor characterised by the composition containing organic or inorganic compounds characterised by the fats used
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03—Organic compounds
    • A23L29/035—Organic compounds containing oxygen as heteroatom
    • A23L29/04—Fatty acids or derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/10—Production of fats or fatty oils from raw materials by extracting
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/001—Refining fats or fatty oils by a combination of two or more of the means hereafter
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/006—Refining fats or fatty oils by extraction
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/008—Refining fats or fatty oils by filtration, e.g. including ultra filtration, dialysis
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/02—Refining fats or fatty oils by chemical reaction
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/10—Refining fats or fatty oils by adsorption
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/12—Refining fats or fatty oils by distillation
    • C11B3/14—Refining fats or fatty oils by distillation with the use of indifferent gases or vapours, e.g. steam
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B7/00—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils
    • C11B7/0075—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils by differences of melting or solidifying points
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2300/00—Processes
    • A23V2300/18—Fractionation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92—Oral administration

Definitions

  • the present invention relates to a concrete avocado oil obtained characterized in that it has a palmitic acid content significantly higher than conventional avocado oil.
  • the invention also relates to the use of said oil in the cosmetic, pharmaceutical and food fields.
  • Virgin or refined avocado oil obtained by cold pressing or by water extraction (so-called centrifugal method), is an oil commonly used in cosmetics for its nutritive, emollient and diaper penetrating properties. upper epidermis. It is also appreciated in cosmetics for its good relative stability to oxidation and its natural vitamin E content (alpha tocopherol (Woolf & coll., Gourmet & Health-Promoting Specialty OIIs, pp 73-125, Edited by Robert A. Moreau and Ataf Kamal-Eldin. AOCS Press 2009.).
  • avocado oil has undergone spectacular development in human nutrition, particularly in the United States and the United Kingdom. Much appreciated for its health benefits linked to its high content of monounsaturated fatty acids and antioxidants, it now competes directly with olive oil (Hilary S. First Report on Quality and Purity of Avocado oil Sold in the US. Food Control 116 (2020) 107328.). Moreover, in terms of taste, avocado oil has a very slightly buttery aroma, devoid of the often strong notes of first cold-pressed olive oils.
  • the avocado oil is extracted from the pulp of the previously pitted fruit.
  • the avocado Persea Americana Mill.
  • the avocado is a fruit qualified as an oil-bearing fruit because its pulp is very rich in oil (> 15%) and water (60%). Taxonomically, we distinguish races Mexican, Guatemalan and West Indian.
  • the main varieties resulting from the crosses of these breeds and the most cultivated today are the Hass and Fuerte avocado. In Mexico, more than 90% of production is of the Hass variety. This variety is known to be the most concentrated in pulp oil (over 20%).
  • the other varieties cultivated in the world include the Bacon, Pinkerton, Ettinger, Lula, Ryan, Barker, Peruano varieties.
  • Refined avocado oils are obtained from crude avocado oils, and refining consists of chemical neutralization with soda, acid degumming, winterization, discoloration on bleaching earth followed finally by vacuum deodorization.
  • unrefined pulp oil consists mainly of oleic acid (55 to 68%), palmitic acid (13 to 22%) and linoleic acid (9 to 15%).
  • palmitoleic acid we also note the presence of palmitoleic acid at 4 to 10%.
  • refined avocado oils the most widely used in particular in cosmetics and food for the general public, obtained from the Hass variety, tend to have average contents of oleic, palmitic and linoleic acids, respectively close to 60, 12 and 10%.
  • the purpose of refining is to provide clear oils which do not cloud in the cold with a cold resistance of at least 5.5 hours at 0°C, in fact leads to significant losses in fatty acids and in particular in palmitic acid.
  • palmitic acid is of great interest in terms of the skin. Indeed, palmitic acid plays an essential role in the synthesis of ceramides of the stratum corneum, in particular ceramides 1 and 2. These ceramides ensure the integrity of the epidermis and the functionality of the hydrolipidic film in terms of hydration and maintaining epidermal homeostasis (J. McIntosh. Organization of Skin Stratum Corneum Extracellular Matrix Lamellae: Diffraction Evidence for Assymetric Distribution of Cholesterol. Biophysical Journal, Volume 85, September 2003: 1675-1681).
  • Palmitic acid is directly involved in the morphogenesis of the epidermis and the skin barrier effect function ( Mieremet & coll. Contribution of Palmitic Acid to Epidermal Morphogenesis and Lipid Barrier Function in Human Skin Equivalents. International of Molecular Sciences. Int. J.Mol. Science. 2019, 20, 6069. pp 1-18).
  • Palmitic acid is an essential fatty acid which constitutes hair lipids. It is indeed the most abundant acid in the hair fiber with a content of 2760 pg/g of hair (Sang-Sun Song & coll. Prevention of Lipids from Hair by Surface and Internal Modification. Nature Scientific Reports, (2019) , 9-9834). This palmitic acid content is greatly reduced by successive shampoos which tend to degrade the quality of the fibre. Also, it is essential to be able to nourish the hair with a regular supply of palmitic acid via hair care products. Similarly, palmitic acid is also a constituent of the essential ceramides of the hair. Ceramides that play an essential role in maintaining and protecting the hair fiber against external aggressions such as UV, pollution, chemical coloring.
  • palmitic acid is one of the essential nutrients to prevent alopecia.
  • adipocytes which constitute the fatty tissues of the skin and the hair follicle of the body hair.
  • many growth factors interact in the adipocyte-follicle relationship.
  • the hair follicle is thus surrounded by a macro-environment made up of fundamental lipids, among which there is an abundance of palmitic acid, which is also one of the major acids constituting the energy reserves of the adipocyte (Schmidt et al. Unraveling Hair Follicle-Adipocyte Communication Exp Dermatol 2012 November 21(11): 827-830).
  • the fatty acids provided by food stored as an energy reserve in the adipocytes, therefore contribute to the development of the hair follicle, the central organ for the synthesis of the hair fibre. Adequate and adapted nutritional intake could advantageously contribute to the development of healthy hair.
  • palmitic acid is biologically involved in a crucial way at the biological level since it allows an essential step in cell renewal through the palmitoylation of the proteins that make up cell walls (Linder, M.E., "Réversible modification of proteins with thioester-inked fatty acids," Protein Lipidation, F. Tamanoi and D.S. Sigman, eds., pp. 215-40 (San Diego, CA: Academy Press, 2000).
  • the carbohydrates are transformed in vivo into palmitic acid, which is then stored in the adipocytes. While in the prevention of diabetes it is encouraged to limit the consumption of sugars, a controlled nutritional intake of bioavailable palmitic acid constitutes an interesting way to produce lipid reserves without taking the metabolic pathway of sugars.
  • palmitic acid is through the consumption of palm oil, meat and dairy products. But these foods are currently suspected of being the cause of obesity problems and cardiovascular diseases.
  • palm oil which is strongly decried both in food and in cosmetics, tends to be replaced by more sustainable oils.
  • Application CA 2 628 950 describes a process for obtaining an avocado oil rich in triglycerides.
  • the process consists in producing 2 oils by a molecular distillation process: a distillate and a heavy oil corresponding to the distillation residue fraction.
  • the oil from the distillation residue fraction known as the heavy fraction
  • the heavy fraction is enriched in sterols, free of unsaponifiables (such as acetogenins and furan lipids) and partial glycerides (mono and diglycerides) , compared to an oil that has not undergone molecular distillation.
  • unsaponifiables such as acetogenins and furan lipids
  • partial glycerides mono and diglycerides
  • Application PCT/FR01/00814 describes a process for concentrating the unsaponifiables of vegetable oils, among which avocado oil is mentioned.
  • the concentration of unsaponifiables describes a molecular distillation process which leads to an oil concentrated in sterols and fat-soluble vitamins as well as a residue oil (heavy fraction) depleted in unsaponifiables.
  • this process does not lead to an oil enriched in palmitic acid.
  • avocado oils of Malaysian origin are not obtained from avocados of the Hass, Fuerte, Bacon, Pinkerton, Ettinger, Lula, Ryan, Barker and/or Peruano varieties.
  • the Hass variety avocado oils cited are not concrete.
  • Application US 2005/058731 describes an antimicrobial composition comprising avocado oil but does not disclose concrete avocado oil or its palmitic acid content or its melting point.
  • Application EP 1 139 771 describes a food product comprising avocado oil but does not disclose concrete avocado oil, nor its palmitic acid content, nor its melting point.
  • Triglycerides are glycerol esters in which the 3 hydroxyl groups of glycerol are esterified with fatty acids.
  • R1, R2 and R3 being identical or different alkyl chains, saturated or unsaturated. If at least one of R1, R2 and/or R3 is a saturated alkyl chain with 16 carbon atoms (C16:0), this means that the hydroxyl group is esterified with palmitic acid.
  • R1, R2 and/or R3 is an alkyl chain with 16 carbon atoms having unsaturation (C16:1), this means that the hydroxyl group is esterified with palmitoleic acid.
  • R1, R2 and/or R3 are a saturated alkyl chain with 18 carbon atoms (C18:0), this means that the hydroxyl group is esterified with stearic acid. If at least one of R1, R2 and/or R3 is an alkyl chain with 18 carbon atoms having unsaturation (C18:1), this means that the hydroxyl group is esterified with oleic acid.
  • R1, R2 and/or R3 is an alkyl chain with 18 carbon atoms having unsaturation (C18:2), this means that the hydroxyl group is esterified with linoleic acid.
  • a virgin oil is obtained by cold pressing the fruit or fruit pulp.
  • oil is meant an oil obtained after an extraction consisting in treating the fruit pulp (previously peeled and pitted) with hot water followed by centrifugation to separate the water and the fat.
  • crude oil is meant virgin oil or avocado oil, which has not been subjected to a refining process.
  • Refined oil means a virgin oil or an avocado oil that has been subjected to a refining process.
  • the process comprises the following steps: an acid treatment a neutralization step winterization or dewaxing a decolorization step a deodorization step.
  • the acid treatment is preferably an acid conditioning, making it possible to carry out a degumming and to eliminate the phospholipids.
  • Acid treatment is typically carried out using a weak acid, such as phosphoric acid or citric acid, or using a strong acid, such as sulfuric acid or hydrochloric acid .
  • a weak acid such as phosphoric acid or citric acid
  • a strong acid such as sulfuric acid or hydrochloric acid
  • the acid treatment is carried out with stirring, at a temperature between 30 and 70°C.
  • micro-filtration which is a low pressure membrane process, used for the filtration of colloids, or processes using biotechnology such as enzymatic degumming.
  • biotechnology such as enzymatic degumming.
  • the chemical neutralization which typically follows the acid treatment, makes it possible to eliminate the free fatty acids, to rid the oil of the phospholipids which have undergone the conditioning operation, to eliminate the metallic traces, and to facilitate the discoloration by destroying a certain number of pigments and colored compounds of oxidative origin.
  • Chemical neutralization is typically carried out using a basic agent such as soda, potassium carbonate or a tertiary amine (DMHA).
  • DMHA tertiary amine
  • the fatty acids are separated, by centrifugation or filtration, in the form of soaps which also contain the mucilages and various impurities eliminated during this treatment.
  • the discoloration which follows the chemical neutralization, generally makes it possible to eliminate the colored pigments that the neutralization has only very partially destroyed.
  • the bleaching is typically carried out using bleaching earths and/or charcoal, advantageously until a light or very light color of the avocado oil is obtained.
  • the bleaching earths used are natural clays of the montmorillonite type, consisting mainly of calcium and magnesium alumino silicates, and activated by acid treatment.
  • the activated carbons used can be obtained from peat, wood, lignite, coal or coconut shells. These products are typically activated at high temperature, either by steam or by a chemical process.
  • the freezing or winterization step which follows the discoloration, can be carried out at a temperature of between 5 and 18° C., advantageously for 1 to 15 days.
  • refined avocado oil is gradually cooled, preferably with slow stirring, to a temperature of the order of 10 to 12°C.
  • the oil is then maintained at this temperature for 48 hours, then is filtered under pressure. Freezing precipitates triglycerides rich in saturated fatty acids.
  • Deodorization which follows freezing, generally makes it possible to eliminate and extract volatile compounds and malodorous molecules as well as various contaminants such as pesticides and polycyclic aromatic hydrocarbons.
  • the deodorization is typically carried out at a temperature of between 150 and 210° C., advantageously under vacuum, generally under a stream of saturated steam or nitrogen.
  • the deodorization can for example be carried out under a pressure of between 2 and 20 mmHg.
  • the deodorization can be carried out at a temperature of the order of 180 to 200° C., under a pressure of the order of 4 to 6 mmHg.
  • a semi-refined oil is an oil that has undergone partial refining (without the winterization and deodorization steps).
  • Concrete material at 20° C. means an oil having a pour point, determined by the ASTM D 97 method, of between 8 and 15° C.
  • the invention relates to a concrete avocado oil characterized in that its palmitic acid content with respect to total fatty acids is included in a range going from 15 to 35% and its complete melting point is included in a range ranging from 20 to 50°C, avocado oil being obtained from avocado of varieties chosen from the list consisting of Hass, Fuerte, Bacon, Pinkerton, Ettinger, Lula, Ryan, Barker and/or Peruano.
  • the avocado is a Hass and/or Fuerte variety avocado.
  • the avocado is a Hass variety avocado.
  • the concrete avocado oil is not obtained from avocado of ++96 variety of Malaysian origin, in particular as defined in Yanty, N.A.M., Marikkar , J.M.N. 8i Long, K. Effect of Varietal Differences on Composition and Thermal Characteristics of Avocado Oil. J Am Oil Chem Soc 88, 1997-2003 (2011).
  • It also relates to a concrete avocado oil characterized in that its palmitic acid content relative to total fatty acids is within a range ranging from 20 to 30% and its complete melting point is within a range ranging from 20 to 50°C.
  • the full melting point is in the range of 23.0 to 40.0°C.
  • the full melting point is in the range of 25.0 to 35.0°C.
  • the concrete avocado oil according to the invention has a pour point determined by the ASTM D 97 method of between 8 and 15°C.
  • the concrete avocado oil according to the invention has a palmitic acid content increased by more than 25 to 75% relative to the starting raw material, preferably by more than 30 to 60%.
  • the concrete avocado oil according to the invention preferably obtained from avocado of the Hass variety, has a pour point determined by the ASTM D 97 method of between 8 and 15°C.
  • the concrete avocado oil according to the invention preferably obtained from Hass variety avocado, has a palmitic acid content increased by more than 25 at 75% relative to the starting raw material, preferably more than 30 to 60%.
  • the palmitic acid content is increased by at least 40% relative to the starting raw material.
  • the palmitic acid content is increased by at least 50% relative to the starting raw material.
  • starting raw material means an avocado oil obtained by extraction with petroleum ether, in particular according to the protocol as described in the article Yanty N A M et al " Effect of Varietal Differences on Composition and Thermal Characteristics of Avocado Oil", JOURNAL OF THE AMERICAN OIL CHEMISTS' SOCIETY, SPRINGER-VERLAG, BERLIN/HEIDELBERG, vol. 88, no.
  • the concrete avocado oil according to the invention is obtained from co-products resulting from the refining or dewaxing of crude avocado oils, such as by example winterization residues
  • the concrete avocado oil according to the invention is characterized by a palmitic acid content increased by more than 25 to 75% compared to refined avocado oil, preferably by more than 30 to 60% .
  • the concrete avocado oil according to the invention exhibits cold resistance at 0° C. (273 K) of less than 2.0 hours.
  • the concrete avocado oil according to the invention exhibits cold resistance at 0° C. (273 K) of less than 1.5 hours.
  • the concrete avocado oil according to the invention exhibits cold resistance at 0° C. (273 K) of less than 1.0 hours.
  • Cold resistance means the time from which an oil becomes cloudy when it is maintained at a temperature of 0° C. under the conditions as described in the method known as the AOCS Cold Test (Ce 11-53 ).
  • the invention also relates to a concrete avocado oil as defined above, characterized in that it exhibits, in differential thermal analysis, a majority slow melting peak comprised of a majority slow melting peak comprised in an interval ranging from 30.0 to 50.0°C.
  • the invention also relates to a concrete avocado oil as defined above, characterized in that its content of triglycerides in which the palmitic acid is in position 2 of the glycerol is greater than or equal to 10% with respect to to the total triglyceride content.
  • the invention also relates to a concrete avocado oil as defined above, characterized in that its relative content of vector triglycerides of palmitoleic acid is greater than or equal to 4.5% relative to the total content in triglycerides.
  • concrete avocado oil is a source of palmitoleic acid.
  • palmitoleic acid is a constituent fatty acid of the glycerides stored in human adipose tissue. It is produced by biosynthesis from palmitic acid under the action of the enzyme stearoyl-CoA desaturase-1 (D9 desaturase). It is known for its anti-inflammatory and PPAR-alpha activating activity ⁇ Vannice GK & coll (2018).
  • Is Palmitoleic Acid a Plausible Nonpharmacological St rate g y to P revent or Control Chronic Metabolic and Inflammatory Disorders. Molecular Nutrition & Food Research; 62 (1), 1700504).
  • Palmitoleic acid is also the most abundant monoene acid in sebum and which also has significant antimicrobial activity (. JJ Wille & coll. Palmitoleic Acid Isomer (C16: ldelta6) in Human Skin Sebum is Effective against Gram-Positive Bacteria Skin Pharmacol Appl Skin Physiol May-June 2003;16(3), 176-87).
  • the invention also relates to a concrete avocado oil as defined above, characterized in that its relative triolein content is less than or equal to 25%, preferably less than or equal to 23% with respect to the content total triglycerides.
  • the concrete avocado oil according to the invention is characterized in that it exhibits, in differential thermal analysis, a majority slow melting peak between 30.0 and 50.0°C. Consequently, concrete avocado oil is a soft concrete fat at 25°C, unlike virgin or refined avocado oils, which are completely fluid at 25°C and do not present in differential thermal analysis a majority peak of slow melting between 30.0 and 50.0°C.
  • the concrete avocado oil according to the invention is characterized in that it is obtained by extraction in the absence of organic solvent, preferably in the absence of solvent.
  • organic solvent means any solvent comprising organic compounds which contain carbon atoms, in particular solvents of petroleum origin.
  • the concrete avocado oil according to the invention is characterized in that it is obtained by extraction in the absence of petroleum ether.
  • the concrete avocado oil according to the invention is characterized in that it is obtained by at least one winterization step.
  • the concrete avocado oil according to the invention is characterized in that it is obtained by at least one step of winterization and absence of organic solvent, preferably in the absence of solvent.
  • the concrete avocado oil according to the invention preferably obtained from Hass variety avocado, can be obtained from fresh or dehydrated fruits as starting plant raw materials.
  • the concrete avocado oil according to the invention preferably obtained from Hass variety avocado, can also be obtained from crude avocado oils obtained from fresh or dehydrated fruits.
  • the crude oils can be obtained by cold pressing, by extraction using a solvent or supercritical fluids, by aqueous extraction according in particular to the so-called centrifugal method or alternatively aqueous extraction assisted by enzymes.
  • the concrete avocado oil according to the invention preferably obtained from avocado of the Hass variety, can also be obtained from by-products resulting from the refining or dewaxing of crude avocado oils, such as by example winterization residues.
  • the concrete avocado oil is prepared from winterization residues resulting from the dewaxing of crude avocado oils, virgin oils, semi-refined oils or even refined oils.
  • the concrete avocado oil according to the invention preferably obtained from avocado of the Hass variety, is refined according to a process identical to those used in the field of vegetable oils.
  • Refining process means a physical or chemical refining process. Refining includes all known steps or at least one of them. These steps are as follows:
  • bleaching on bleaching earth in the presence of activated clay or not) and/or in the presence of activated carbon, with or without silicate;
  • the concrete avocado oil can undergo a second or more successive cold crystallization stages in order to increase the palmitic acid content.
  • the invention relates to a process for obtaining a concrete avocado oil, preferably obtained from Hass variety avocado, characterized in that it is implemented from:
  • the process for obtaining a concrete avocado oil is implemented from co-products resulting from the refining or dewaxing of crude avocado oils, preferably winterization residues, or it comprises a step of using co-products from the refining or dewaxing of crude avocado oils, preferably winterization residues, it has the advantage of using a conventionally non-recovered co-product of the avocado oil preparation process.
  • the concrete oil thus obtained is therefore of significant interest from an ecological and environmental point of view.
  • the invention also relates to a process for obtaining a concrete avocado oil as described above, characterized in that it is implemented from:
  • the invention also relates to a process for obtaining a concrete avocado oil, as described above, characterized in that it is implemented from:
  • the invention also relates to a process for obtaining a concrete avocado oil, preferably obtained from avocado of the Hass variety, as described above, characterized in that it is implemented at leave :
  • the invention also relates to a process for obtaining a concrete avocado oil preferably obtained from avocado of the Hass variety, as previously described, characterized in that it is implemented from :
  • the invention also relates to a process for obtaining a concrete avocado oil, as described above, characterized in that it is implemented from:
  • the process for obtaining a concrete avocado oil preferably obtained from avocado of the Hass variety, as described above, characterized in that it is implemented from:
  • the invention also relates to a method of obtaining as described above, characterized in that it comprises, before the deodorization step, at least one of the following steps:
  • the invention also relates to a process for obtaining such as described above, characterized in that it further comprises a step of fractionation by hydrolysis.
  • the concrete avocado oil according to the invention is in the form of a concrete raw material at 20° C. having emollient and spreading properties, in particular spreadable properties.
  • the concrete avocado oil according to the invention is characterized in that it can easily be formulated for the preparation of cosmetic and food products.
  • the invention also relates to a cosmetic or pharmaceutical composition, characterized in that it comprises, in a cosmetically or pharmaceutically acceptable carrier, a concrete avocado oil according to the invention.
  • a cosmetic or pharmaceutical composition according to the invention is characterized in that it also comprises an active principle.
  • the concrete avocado oil according to the invention is intended to be incorporated into cosmetic products as active ingredient or functional raw material.
  • the invention also relates to the use of the concrete oil according to the invention, for the preparation of cosmetic and/or nutraceutical composition.
  • the invention also relates to the use of the concrete oil according to the invention, preferably obtained from avocado of the Hass variety, for the preparation of cosmetic and/or nutraceutical composition.
  • Cosmetic product means any substance or any mixture intended to be brought into contact with the healthy superficial parts of the human body (healthy epidermis, healthy hair and capillary systems, healthy nails, healthy lips and healthy external genitalia) or with healthy teeth and healthy oral mucous membranes with a view, exclusively or mainly, to cleaning them, perfuming them, modifying their appearance, protecting them, keeping them in good condition or correcting body odors (Article 2 cosmetic regulation and article L.5131-1 of the CSP).
  • the concrete avocado oil according to the invention can be incorporated into the various categories of cosmetic products which are products for healthy skin, hygiene products, hair products, depilatory products, products for nail care and makeup.
  • Products for healthy skin are understood to mean creams, emulsions, lotions, gels and oils for the skin, beauty masks, liquid foundations, pastes and/or powders, powders for make-up, powders to be applied after bathing, powders for personal hygiene, preparations for baths and showers chosen in particular from salts, foams, oils and/or gels, sunscreen products, tanning products without sun, products for whitening the skin, anti-wrinkle products, shaving products chosen in particular from soaps, foams and/or lotions, make-up and make-up removal products, products intended to be applied to the lips.
  • hygiene products toilet soaps, deodorant soaps, dental and oral hygiene products, external intimate hygiene products, deodorants and antiperspirants.
  • Hair products are understood to mean hair dyes, products for waving, straightening and setting the hair, styling products, hair cleaning products chosen in particular from lotions, powders and/or shampoos, hair care products chosen in particular from lotions, creams and/or oils, styling products chosen in particular from lotions, lacquers and /or brilliantines.
  • the concrete avocado oil according to the invention is incorporated into a composition that is physiologically, cosmetologically and dermatologically acceptable.
  • This composition can be aqueous, aqueous-alcoholic or even comprise an aqueous phase combined or not with an oily phase.
  • the composition containing the concrete avocado oil according to the invention can be a single or triple emulsion which may or may not contain liposomes, niosomes or even oleosomes .
  • emulsions can be nano or microemulsions.
  • compositions intended for the skin and hair may contain moisturizing and humectant agents chosen without limitation from the group consisting of alpha, beta and gamma hydroxy acids (in particular lactic, malic, citric, glycolic, tartaric and gluconic acids) , sodium-2 pyrrolidone, mucopolysaccharides, proteoglycans, glycoaminoglycans, glucans, glycols (glycerol, polyglycerols, propylene glycol, 1,3 propanediol, pentanediol, hexanediol), hyaluronic acid, protein hydrolysates, soluble collagens, urea, D-panthenol, vitamin E esters (linoleate, acetate), lanolin and its derivatives.
  • moisturizing and humectant agents chosen without limitation from the group consisting of alpha, beta and gamma hydroxy acids (in particular lactic, malic, citric
  • compositions intended for the skin and hair may contain hydrophilic and/or lipophilic emollients, belonging in a non-limiting way to the group consisting of vegetable oils, synthetic triglycerides (medium-chain triglycerides for example), vegetable butters and synthetic oils, hydrogenated oils, benzoic acid esters, mineral oils, linear and branched hydrocarbons of mineral or vegetable origin, ethers, fatty acid esters, synthetic fatty alcohols and of vegetable origin , Guerbet alcohols, glycol esters (for example propylene glycol di-caprylate/caprate), polyethylene and propylene glycol esters, silicones (in particular volatile cyclomethicones, linear polysiloxanes such as dimethicones and alkyl or phenyl trimethicones).
  • hydrophilic and/or lipophilic emollients belonging in a non-limiting way to the group consisting of vegetable oils, synthetic triglycerides (medium-chain triglycerides for
  • compositions for skin and hair may contain thickening agents which may belong, without limitation, to the group consisting of mineral, vegetable and synthetic waxes (example: carnauba, candelilla, sunflower wax), hydrogenated glycerides , fatty acids, fatty alcohols, cellulose derivatives (in particular methyl, ethyl and propyl cellulose, carboxymethylcellulose), starch and its derivatives (dextrose, dextrins, sodium starch polyacrylate, aluminum octylsuccinate), natural gums (arabic, guar, carob, tragacanth), pectins, agar, alginates, carrageenans, xanthan gums, gelatin, mineral oxides (silica, bentonite, aluminosilicates), stearates of aluminum and magnesium, zinc stearate, crosslinked or non-crosslinked carbomers, C10-C30 alkyl acrylates, polyolefins such as polybutylene glycol
  • compositions intended for the skin and hair in the form of emulsions contain emulsifying surfactants in known manner.
  • these emulsifiers belong to the group consisting of cationic, anionic, nonionic and amphoteric surfactants.
  • These agents include fatty acid soaps, alkyl sulfates, alkyl ether sulfates, alkyl sulfonates, alkyl and olefin sulfonates, sulfosuccinates, acyl isothionates, sulfated alkanolamides, imidazole sulfates, taurine and methyl taurine sulfonates, alkyl phosphates, quaternary ammoniums, ethoxylated amines, imidazolines, alkyl amines, lecithins, ethoxylated fatty alcohols and phenyl alcohols, sucroesters (of sorbitol, of glucose, of sucrose), oxyethylenated sugars, alkylpolyglucosides (APG) , monoglycerides, polyglycerol esters, dimethicone copolyols.
  • APG alkylpoly
  • compositions intended for the skin and hair can also be sun protection products. Consequently, the sunscreen compositions contain, without limitation, chemical filters and mineral filters. Among these filters we find in a non-limiting way, UV-B and UV-A filters such as octyl methylcinnamate, methyl benzylidene camphor, phenylbenzimidazole sulphonic acid, octyl triazole, avobenzone, octyl sallycilate, octyl dimethyl paba, octocrylene, benzophenones, methyl anthralinate, zinc and titanium oxides.
  • UV-B and UV-A filters such as octyl methylcinnamate, methyl benzylidene camphor, phenylbenzimidazole sulphonic acid, octyl triazole, avobenzone, octyl sallycilate, octyl dimethyl p
  • compositions intended for the skin and hair may contain the usual agents such as active principles, preservatives, perfumes, pigments, complexing agents, anti-odors, anti-perspirants, antioxidants, solvents ( alcohols, glycols).
  • the concrete avocado oil according to the invention is incorporated as an agent for the cosmetic treatment of healthy keratin fibers (healthy skin, healthy hair, healthy nails, healthy eyelashes).
  • the invention therefore also relates to the use of the concrete oil according to the invention, as an active ingredient for the cosmetic treatment of healthy skin and/or healthy keratin fibers, in particular healthy hair, healthy nails and/or healthy eyelashes.
  • the invention therefore also relates to the use of the concrete oil according to the invention, preferably obtained from avocado of the Hass variety, as an active ingredient for the cosmetic treatment of healthy skin and/or healthy keratin fibres, in particular healthy hair, healthy nails and/or healthy eyelashes.
  • More particularly concrete avocado oil is a lipid-replenishing, nutritive, moisturizing agent, constituent of the hydrolipidic film but also as a promoter of the synthesis of epidermal lipids, as an agent for treating mature skin, winter xerosis, atopy, eczema, alopecia, dandruff or even keratin fibers attacked by UV rays or aggressive substances (shampoos, substances used in hair coloring, drugs, etc.).
  • the invention therefore relates to the cosmetic use of the concrete oil according to the invention, as a lipid-replenishing, nutritive, anti-dandruff and/or moisturizing agent for healthy skin, in particular healthy scalp and/or for the cosmetic treatment of healthy skin and/or healthy keratin fibers attacked by UV rays or aggressive substances, in particular shampoos, substances used in hair coloring and/or medicines.
  • the invention also relates to the concrete oil according to the invention, for its pharmaceutical use, preferably dermatological, for preventing and/or treating winter xerosis, atopy, eczema and/or alopecia.
  • the concrete avocado oil according to the invention is also incorporated as a substitute for mineral oils and lanolins.
  • the concrete avocado oil according to the invention is also incorporated to combat the effects of actinic, chronological and photo-induced ageing. It can also be used as an anti-pollution and anti-allergenic film-forming agent or even as a protector of the skin microbiota.
  • the cosmetic composition according to the invention is characterized in that it comprises from 0.1 to 95.0% by mass of concrete avocado oil according to the invention with respect to the total mass of said composition.
  • the cosmetic composition according to the invention is characterized in that it comprises from 1.0 to 90.0% by mass of concrete avocado oil according to the invention with respect to the total mass of said composition.
  • the cosmetic composition according to the invention is characterized in that it comprises from 2.0 to 75.0% by mass of concrete avocado oil according to the invention with respect to the total mass of said composition.
  • concrete avocado oil will be associated with a surfactant of chemically transformed vegetable origin chosen in the group consisting of lecithins, alkyl betaines, ethoxylated fatty alcohols, PEG and PPG esters, sucroesters, oxyethylenated sugars, sorbitol esters, alkylpolyglucosides (APG), monoglycerides, polyglycerol esters, alkyl sulfates, alkyl ether sulfates and sulfonates.
  • a surfactant of chemically transformed vegetable origin chosen in the group consisting of lecithins, alkyl betaines, ethoxylated fatty alcohols, PEG and PPG esters, sucroesters, oxyethylenated sugars, sorbitol esters, alkylpolyglucosides (APG), monoglycerides, polyglycerol esters, alkyl sulfates, alkyl ether s
  • concrete avocado oil (CHA) will be associated with a thickening agent of chemically transformed vegetable origin chosen from the group consisting of alginates, carrageenans, celluloses and modified starches, pectins, xanthan, guar, arabic gums.
  • concrete avocado oil (CHA) will be associated with an emollient agent of chemically transformed plant origin chosen from the group consisting of C8 to C18 fatty acid esters. and alkanes.
  • concrete avocado oil will be combined with a vegetable lipid or with one of its fractions, chosen from the group consisting of coconut, palm and , palm kernel, olive, argan, soy, sunflower, rapeseed, rice bran, corn, cotton, wheat germ, sweet almond, avocado, safflower; hemp, walnut, hazelnut, camelina, evening primrose, borage, blackcurrant, moringa, andiroba, jojoba, macadamia, Brazil nut, crambe, karanja, passionflower, castor, flax, pracaxi, buruti, baobab, calendula, pumpkin seed, sesame, grapeseed, cuphea, babassu, marula, passionflower, apricot, chia, cranberry, perilla, raspberry, blueberry, shea butters, cocoa, mango, illipe, cupuacu, murumuru, kokum, sal
  • concrete avocado oil will be associated with a surfactant of chemically transformed plant origin chosen from the group consisting of lecithins, alkyl betaines, ethoxylated fatty alcohols, PEG esters and PPG, sucroesters, oxyethylenated sugars, sorbitol esters, alkyl polyglucosides (APG), monoglycerides, polyglycerol esters, alkyl sulphates, alkyl ether sulphates and sulphonates.
  • a surfactant of chemically transformed plant origin chosen from the group consisting of lecithins, alkyl betaines, ethoxylated fatty alcohols, PEG esters and PPG, sucroesters, oxyethylenated sugars, sorbitol esters, alkyl polyglucosides (APG), monoglycerides, polyglycerol esters, alkyl sulphates, alkyl ether sulphates and sul
  • concrete avocado oil will be associated with a vegetable lipid or with one of its fractions, chosen from the group consisting of coconut, palm, palm kernel, olive and argan oils. , soy, sunflower, rapeseed, rice bran, corn, cotton, wheat germ, sweet almond, avocado, safflower; hemp, walnut, hazelnut, camelina, evening primrose, borage, blackcurrant, moringa, andiroba, jojoba, macadamia, Brazil nut, crambe, karanja, passionflower, castor, flax, pracaxi, buruti, calendula, baobab, pumpkin seed, sesame, grapeseed, cuphea, babassu, marula, passionflower, apricot, chia, cranberry, perilla, raspberry, blueberry, shea butters, cocoa, mango, illipe, cupuacu, murumuru, kokum, sal.
  • concrete avocado oil will be associated with a vegetable lipid or with one of its fractions, chosen from the group consisting of coconut, palm, palm kernel, olive and argan oils. , soy, sunflower, rapeseed, rice bran, corn, cotton, wheat germ, sweet almond, avocado, safflower; hemp, walnut, hazelnut, camelina, evening primrose, borage, blackcurrant, moringa, andiroba, jojoba, macadamia, Brazil nut, crambe, karanja, passionflower, castor, flax, pracaxi, buruti, calendula, baobab, pumpkin seed, sesame, grapeseed, cuphea, babassu, marula, passionflower, apricot, chia, cranberry, perilla, raspberry, blueberry, shea butters, cocoa, mango, illipe, cupuacu, murumuru, kokum, sal.
  • concrete avocado oil will be combined with a wax of vegetable or animal origin chosen from the group consisting of carnauba wax, candelilla, rice bran, sunflower , castor, jojoba, bee.
  • the invention also relates to a food composition, characterized in that it comprises a concrete avocado oil according to the invention.
  • the concrete avocado oil according to the invention is intended to be incorporated into food products as active principle or functional raw material.
  • food product is meant foods for everyday consumption, food supplements as well as clinical nutrition.
  • the concrete avocado oil according to the invention can be advantageously incorporated into solid, liquid or sprayable food compositions based on lipids and more particularly, table oils, frying oils, margarines, pasta spreads, pastries, ready meals, chocolate products and confectionery.
  • Concrete avocado oil can also be used in food compositions as a thickening agent, rheology modifier, film former, coating agent, lubricant, carrier for additives, flavorings and vitamins.
  • the concrete avocado oil according to the invention can also be incorporated into solid or liquid food supplements, in particular in a water-dispersible form or even more advantageously in soft capsules.
  • the concrete avocado oil according to the invention is incorporated as a re-balancing agent for monounsaturated fatty acid intake or as a source of palmitic and palmitoleic acid.
  • the concrete avocado oil according to the invention is a lipid-replenishing, nutritive, moisturizing agent, reconstituting the hydrolipidic film but also as a promoter of the synthesis of epidermal lipids, as an agent for treating mature skin, winter xerosis, atopy, eczema, alopecia, dandruff or even keratin fibers attacked by UV rays or aggressive substances chosen in particular from shampoos, substances used in hair coloring and/or medicaments.
  • the invention relates to the use as an active ingredient in food supplements for cosmetic purposes, of the concrete oil according to the invention, as a lipid-replenishing, nutritive, anti-dandruff and/or moisturizing agent for the skin.
  • healthy in particular of the healthy scalp and/or for the cosmetic treatment of healthy skin and/or healthy keratin fibers damaged by UV rays or aggressive substances, in particular shampoos, substances used in hair coloring and/or medicines.
  • the food composition according to the invention is characterized in that it comprises from 0.1 to 98.0% by mass of concrete avocado oil according to the invention with respect to the total mass of said composition.
  • the food composition according to the invention is characterized in that it comprises from 1.0 to 90.0% by mass of concrete avocado oil according to the invention with respect to the total mass of said composition.
  • the food composition according to the invention is characterized in that it comprises from 2.0 to 75.0% by mass of concrete avocado oil according to the invention with respect to the total mass of said composition.
  • concrete avocado oil will be associated with a vegetable lipid or with one of its fractions, chosen from the group consisting of coconut, palm, palm kernel, olive, soy, sunflower, rapeseed, rice bran, corn, cotton, wheat germ, avocado, safflower; hemp, walnut, hazelnut, camelina, evening primrose, borage, blackcurrant, flax, pumpkin seed, sesame, grape seed, chia, cranberry, perilla, shea butter, cocoa, mango, sal.
  • coconut, palm, palm kernel olive, soy, sunflower, rapeseed, rice bran, corn, cotton, wheat germ, avocado, safflower; hemp, walnut, hazelnut, camelina, evening primrose, borage, blackcurrant, flax, pumpkin seed, sesame, grape seed, chia, cranberry, perilla, shea butter, cocoa, mango, sal.
  • concrete avocado oil will be associated with a vitamin chosen from the group consisting of vitamin A, C, E, D, K, Bl, B2, B3, B5, B6, B8, B9, B12, niacin, folic acid, pantothenic acid and biotin.
  • concrete avocado oil will be associated with a mineral salt chosen from the group consisting of calcium, magnesium, iron, copper, iodine, zinc, manganese, potassium, selenium , chromium, molybdenum, fluoride, chlorine and phosphorus.
  • Example 1 Preparation of a Refined avocado Oil and of a Concrete avocado Oil
  • 20 kg of fresh avocado of the Hass variety of Mexican origin are peeled and pitted to extract the pulp.
  • the pulp is then ground in a blender to obtain a homogeneous puree.
  • 20 liters of hot water at 60° C. are then added to a stirred reactor and the mixture is stirred at 500 rpm for 40 minutes.
  • the mixture is then centrifuged to separate the liquid phase consisting of a water-oil emulsion.
  • the operation is repeated 3 times.
  • the liquid phases are then left to stand for 10 hours in order to separate the water and the oil by decantation.
  • 1.81 kg of crude avocado oil are recovered.
  • the oil obtained has an acidity of 1.5% in oleic acid equivalent.
  • a fluid oil (MG 1) and 262 g of filter cake are then recovered in the form of a concrete fat (MG 2).
  • the fluid oil MG1 and the concrete fat MG 2 are separately deodorized under vacuum at 200° C., under a vacuum of 5 mbar and by continuous injection of steam (2 g of steam per 100 g of body fat), for 90 minutes.
  • the refined fluid oil Al and a concrete oil at 20° C. according to the invention are then obtained respectively (concrete avocado oil El).
  • the concrete oil of avocado El has a palmitic acid content increased by more than 44% compared to the refined avocado oil obtained according to a conventional process (oil Al);
  • the palmitoleic acid content of the concrete oil of avocado El is very slightly higher than oil Al;
  • concrete avocado oil El is an ingredient enriched in palmitic acid without significant alteration of the nutritional qualities of conventional avocado oil in terms of monounsaturated, polyunsaturated and unsaponifiable fatty acids.
  • Table 2 Comparative analysis of the triglyceride composition of Al oil and El avocado concrete oil.
  • radicals derived from fatty acids are abbreviated as: - L for linoleic acid,
  • Concrete avocado oil El and oil Al have a completely different composition of triglycerides;
  • the concrete oil of avocado El is enriched with triglycerides PPoO, PoOO, PPL, PPP, and PPL and in particular, with triglycerides in which the palmitic acid is in position sn2 of the glycerol, that is to say say the most bioavailable position orally.
  • the concrete oil of avocado El is also enriched in triglycerides vectors of palmitoleic acid (PPoO and PoOO).
  • the concrete oil of avocado El is an ingredient enriched in palmitic acid that is highly bioavailable through food.
  • Example 2 “body care cream” cosmetic composition containing concrete avocado oil.
  • Example 3 cosmetic composition of deodorant stick containing concrete avocado oil.
  • Example 4 food supplement composition in soft capsules containing the avocado oil extract.
  • Example 5 food composition of chocolate spread containing concrete avocado oil.
  • Example 6 Substitution of conventional avocado oil in a cosmetic cream/Effect on the amount of thickener
  • 2 formulations of mayonnaise are prepared according to the same operating procedure which consists in emulsifying, using a homogenizer, a first phase consisting of water, a thickener and an aroma.
  • the egg yolk, the sodium chloride and the preservative, the vinegar and finally the avocado vegetable oil are then added in 4 distinct and successive stages.
  • the preparation is carried out at a temperature of 20° C. and under a vacuum of 400 mbar.
  • the 2 formulations are kept in the refrigerator at 5° C. and in contact with air for 15 days.
  • the compositions and characteristics of these 2 formulations are shown in the table below:
  • formulas A and B which have identical contents of refined avocado oil Al and concrete avocado oil El, differ in their respective contents of thickening agent (guar gum). However, it is observed that their viscosity is substantially identical whereas the guar gum content of formula B has been reduced by more than 35%. This result demonstrates that the concrete oil of avocado El according to the invention exhibits an intrinsic thickening activity and makes it possible to reduce the quantity of thickening agent.
  • the Rancimat method is an accelerated aging test. During a constant increase in temperature in the reaction vessel, air is forced through the sample. It measures the time it takes for the product to oxidize and defines the oxidation induction or stability time (OSI).
  • OSI oxidation induction or stability time
  • the refined avocado oil Al and the concrete avocado oil El according to the invention were the subject of this analysis according to standard NF EN ISO 6886. The results obtained are collated in the table below:
  • the concrete oil of avocado El according to the invention has an induction time significantly greater than that of conventional avocado oil Al and therefore a better resistance to oxidation.
  • Example 9 (comparatifl-Concrete oil of avocado according to the invention as a source of palmitic acid of high purity
  • the oily phase is then separated from the heavy aqueous phase and then washed in a stirred reactor in the presence of 100 ml of hot water (60° C.). After decantation and recovery of the oily phase, the operation is repeated until the washing water is neutral.
  • the oily phase is then dried under vacuum (100 mbar) on a rotary evaporator.
  • the oily phase is then stored at 12° C. for 24 hours in order to crystallize the saturated fatty acids.
  • the mixture is then filtered through a Büchner filter and the cake washed 3 times with 100 ml of cold hexane (15° C.). The cake obtained is finally dried under study at 40° C. for 10 hours.
  • the palmitic acid content of the fatty acids obtained from the concrete oil of avocado El according to the invention is 96% and proves to be significantly higher than that of the fatty acids obtained from refined palm oil. . Therefore, concrete oil of avocado El makes it possible to obtain palmitic acid of higher purity.
  • Example 10 Comparison of the physicochemical and organoleptic stability of a cosmetic oil-in-water emulsion PH/E1 based on mineral oil, refined avocado oil or concrete avocado oil according to 'invention
  • An emulsion A is prepared from concrete avocado oil according to the invention as prepared in Example 1 (concrete avocado oil El), an emulsion B comprising a paraffin oil (INCI: Paraffinum Liquidum) sold under the name of CODEX STANDARD L PARAFFIN OIL by the company AiglonTM, and an emulsion C comprising a refined avocado oil VIRGIN and BIOLOGICAL AVOCADO OILTM from the company EMILE NO ⁇ LTM, all elements being equal by elsewhere, according to the following protocol.
  • a paraffin oil INCI: Paraffinum Liquidum
  • CODEX STANDARD L PARAFFIN OIL by the company AiglonTM
  • an emulsion C comprising a refined avocado oil VIRGIN and BIOLOGICAL AVOCADO OILTM from the company EMILE NO ⁇ LTM, all elements being equal by elsewhere, according to the following protocol.
  • the Concrete Avocado El oil according to the invention or Paraffin oil (Paraffinum Liquidum), or refined avocado oil is mixed with the Caprylic triglyceride / Capric and the mixture of cetearyl alcohol and cetearyl glucoside in the proportions indicated in the table below below to reach a total weight of 300 grams.
  • the mixture is heated up to 80°C under magnetic stirring and constitutes phase 1.
  • the water, glycerin, xanthan gum and the phenoxyethanol mixture are mixed and Parabens. This mixture is heated to 80°C with magnetic stirring and constitutes phase 2.
  • phase 1 is slowly poured into phase 2, with rotor/stator stirring, at a speed of 3000 rpm. Stirring is maintained for 5 minutes then the mixture is cooled using a cold water bath, with planetary stirring, at a stirring speed of between 700 and 1200 rpm, until the temperature of the emulsion thus obtained reaches 30°C.
  • the viscosity measurement was performed using a NEWTRY NDJ-1 brand viscometer, using rotor No. 4, and a speed of 30 revolutions/s.
  • emulsions A and B have a similar appearance, pH, color and smell.
  • the concrete avocado oil according to the invention induces a slight increase in viscosity, without this modifying the fluidity of the emulsion.
  • emulsion C is very tinted with a very marked vegetable odor.
  • the emulsion comprising concrete avocado oil according to the invention therefore has a significant advantage over the emulsion comprising refined avocado oil, in particular for uses for cosmetic, pharmaceutical or food formulations over with refined avocado oil.
  • Emulsions A and B are then subjected to an accelerated aging test carried out in an oven at 45° C., in air and for 60 days. [000188] Appearance, color and smell are estimated organoleptically.
  • IP peroxide index
  • the viscosity index is measured using a NEWTRY NDJ-1 brand viscometer, using rotor No. 4, and a speed of 30 revolutions/s.
  • balm A concrete oil of avocado El according to the invention as prepared in Example 1
  • balm B a commercial paraffin oil sold by the company AiglonTM
  • balms A and B are reproduced below:
  • Balms A and B are then subjected to an accelerated aging test carried out in an oven at 45° C., in air and for 60 days.
  • IP peroxide index
  • the concrete avocado oil according to the invention has an oxidation resistance identical to that of mineral oil without adding antioxidants to the formula.
  • rapeseed oil (INCI name Brassica Campestris Seed Oil).
  • this oil known for its poor resistance to oxidation, is largely responsible for the increase in the peroxide index of the two balms. Consequently, in the absence of antioxidant, the concrete avocado oil according to the invention reinforces the protection of the rapeseed oil against oxidation within the formula and this, in an almost identical way to the oil of paraffin.
  • Example 12 Comparison of the sensory properties of a cosmetic oil-in-water emulsion PH/E1 based on mineral oil or concrete avocado oil according to the invention
  • a sensory analysis is carried out on a panel of 20 women with emulsions A and B as prepared in Example 10, in order to compare the sensory performance of an emulsion comprising a concrete avocado oil according to the invention. and a conventional paraffin oil emulsion.
  • emulsion A comprising concrete avocado oil according to the invention results equivalent to emulsion B comprising paraffin oil.
  • the cosmetic compositions in the form of an emulsion comprising the concrete avocado oil according to the invention therefore have a certain sensory advantage for the user compared to the cosmetic compositions comprising a paraffin oil. .

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EP22717404.2A 2021-03-31 2022-03-31 Mit palmitinsäure angereichertes festes avocadoöl Pending EP4312575A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR2103333A FR3121329A1 (fr) 2021-03-31 2021-03-31 Huile concrète d’avocat enrichie en acide palmitique
PCT/EP2022/058720 WO2022207886A1 (fr) 2021-03-31 2022-03-31 Huile concrete d'avocat enrichie en acide palmitique

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EP4312575A1 true EP4312575A1 (de) 2024-02-07

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US (1) US20240156714A1 (de)
EP (1) EP4312575A1 (de)
KR (1) KR20240001698A (de)
CN (1) CN117813011A (de)
BR (1) BR112023020246A2 (de)
FR (1) FR3121329A1 (de)
WO (1) WO2022207886A1 (de)

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SE514725C2 (sv) * 1998-06-02 2001-04-09 Karlshamns Ab Fraktioneringsförfarande
CN1170479C (zh) * 1999-01-04 2004-10-13 艾格-奥里芙石油产品工业有限公司 食品涂抹料
AU2002350214A1 (en) * 2001-11-30 2003-06-17 Almell, Ltd. Antimicrobial composition comprising soy oil, rice bran oil and jojoba oil
FR2893628B1 (fr) 2005-11-18 2008-05-16 Expanscience Laboratoires Sa Procede d'obtention d'une huile d'avocat raffinee riche en triglycerides et huile susceptible d'etre obtenue par un tel procede

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FR3121329A1 (fr) 2022-10-07
US20240156714A1 (en) 2024-05-16
BR112023020246A2 (pt) 2023-12-19
CN117813011A (zh) 2024-04-02
KR20240001698A (ko) 2024-01-03

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