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EP4172353A4 - ELECTRONIC CONTROL OF THE PH VALUE OF A SOLUTION CLOSE TO AN ELECTRODE SURFACE - Google Patents

ELECTRONIC CONTROL OF THE PH VALUE OF A SOLUTION CLOSE TO AN ELECTRODE SURFACE Download PDF

Info

Publication number
EP4172353A4
EP4172353A4 EP21843496.7A EP21843496A EP4172353A4 EP 4172353 A4 EP4172353 A4 EP 4172353A4 EP 21843496 A EP21843496 A EP 21843496A EP 4172353 A4 EP4172353 A4 EP 4172353A4
Authority
EP
European Patent Office
Prior art keywords
value
electronic control
electrode surface
solution close
close
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21843496.7A
Other languages
German (de)
French (fr)
Other versions
EP4172353A1 (en
Inventor
Christopher Johnson
Sam Kavusi
Nadezda Fomina
Habib Ahmad
Autumn MARUNIAK
Christoph Lang
Ashwin Raghunathan
Young Shik Shin
Armin Darvish
Efthymios Papageorgiou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robert Bosch GmbH
Original Assignee
Robert Bosch GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/932,096 external-priority patent/US11867660B2/en
Application filed by Robert Bosch GmbH filed Critical Robert Bosch GmbH
Publication of EP4172353A1 publication Critical patent/EP4172353A1/en
Publication of EP4172353A4 publication Critical patent/EP4172353A4/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/302Electrodes, e.g. test electrodes; Half-cells pH sensitive, e.g. quinhydron, antimony or hydrogen electrodes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/34Dropping-mercury electrodes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/4166Systems measuring a particular property of an electrolyte
    • G01N27/4167Systems measuring a particular property of an electrolyte pH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/27Association of two or more measuring systems or cells, each measuring a different parameter, where the measurement results may be either used independently, the systems or cells being physically associated, or combined to produce a value for a further parameter
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP21843496.7A 2020-07-17 2021-07-16 ELECTRONIC CONTROL OF THE PH VALUE OF A SOLUTION CLOSE TO AN ELECTRODE SURFACE Pending EP4172353A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16/932,096 US11867660B2 (en) 2015-07-06 2020-07-17 Electronic control of the pH of a solution close to an electrode surface
PCT/US2021/042031 WO2022016087A1 (en) 2020-07-17 2021-07-16 Electronic control of the ph of a solution close to an electrode surface

Publications (2)

Publication Number Publication Date
EP4172353A1 EP4172353A1 (en) 2023-05-03
EP4172353A4 true EP4172353A4 (en) 2024-07-24

Family

ID=79555028

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21843496.7A Pending EP4172353A4 (en) 2020-07-17 2021-07-16 ELECTRONIC CONTROL OF THE PH VALUE OF A SOLUTION CLOSE TO AN ELECTRODE SURFACE

Country Status (5)

Country Link
EP (1) EP4172353A4 (en)
JP (1) JP7493091B2 (en)
KR (1) KR20230124541A (en)
CN (1) CN116685846A (en)
WO (1) WO2022016087A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017077384A1 (en) * 2015-11-04 2017-05-11 Robert Bosch Gmbh Integration of electrochemical ph modulation with lab on a chip technologies

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020022261A1 (en) 1995-06-29 2002-02-21 Anderson Rolfe C. Miniaturized genetic analysis systems and methods
DE102005060866B4 (en) * 2005-12-20 2009-01-15 Bruker Biospin Gmbh Combined titration and pH electrode for the preparation of liquid samples, especially for NMR spectroscopy
JP4370406B2 (en) 2006-03-08 2009-11-25 国立大学法人 筑波大学 pH stat and pH change measuring method
US9075041B2 (en) 2012-07-06 2015-07-07 Robert Bosch Gmbh Methods for generating pH/ionic concentration gradient near electrode surfaces for modulating biomolecular interactions
US9810688B2 (en) 2013-03-15 2017-11-07 Robert Bosch Gmbh Smart glass slide for microarrays
US10011549B2 (en) 2015-07-06 2018-07-03 Robert Bosch Gmbh Electrochemically active agents for pH modulation in biological buffers
US10379080B2 (en) * 2015-07-06 2019-08-13 Robert Bosch Gmbh Electronic control of the pH of a solution close to an electrode surfaces
US10532356B2 (en) * 2017-11-09 2020-01-14 International Business Machines Corporation pH control for analyte detection

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017077384A1 (en) * 2015-11-04 2017-05-11 Robert Bosch Gmbh Integration of electrochemical ph modulation with lab on a chip technologies

Also Published As

Publication number Publication date
JP2023540164A (en) 2023-09-22
JP7493091B2 (en) 2024-05-30
EP4172353A1 (en) 2023-05-03
CN116685846A (en) 2023-09-01
KR20230124541A (en) 2023-08-25
WO2022016087A1 (en) 2022-01-20

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Legal Events

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Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20230125

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RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: ROBERT BOSCH GMBH

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20240625

RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/53 20060101ALI20240619BHEP

Ipc: G01N 33/487 20060101ALI20240619BHEP

Ipc: G01N 27/416 20060101ALI20240619BHEP

Ipc: G01N 27/27 20060101ALI20240619BHEP

Ipc: C12Q 1/00 20060101AFI20240619BHEP