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EP3607324A4 - Flow assay with at least one electrically-actuated fluid flow control valve and related methods - Google Patents

Flow assay with at least one electrically-actuated fluid flow control valve and related methods Download PDF

Info

Publication number
EP3607324A4
EP3607324A4 EP18781906.5A EP18781906A EP3607324A4 EP 3607324 A4 EP3607324 A4 EP 3607324A4 EP 18781906 A EP18781906 A EP 18781906A EP 3607324 A4 EP3607324 A4 EP 3607324A4
Authority
EP
European Patent Office
Prior art keywords
electrically
control valve
related methods
actuated fluid
fluid flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP18781906.5A
Other languages
German (de)
French (fr)
Other versions
EP3607324A1 (en
Inventor
David Gasperino
Kevin Paul Flood Nichols
Bernhard Hans Weigl
Benjamin K. Wilson
Ozgur Emek Yildirim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tokitae LLC
Original Assignee
Tokitae LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/482,593 external-priority patent/US10549273B2/en
Application filed by Tokitae LLC filed Critical Tokitae LLC
Publication of EP3607324A1 publication Critical patent/EP3607324A1/en
Publication of EP3607324A4 publication Critical patent/EP3607324A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087Multiple sequential chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427Electrowetting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0688Valves, specific forms thereof surface tension valves, capillary stop, capillary break

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP18781906.5A 2017-04-07 2018-04-05 Flow assay with at least one electrically-actuated fluid flow control valve and related methods Withdrawn EP3607324A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/482,593 US10549273B2 (en) 2014-09-19 2017-04-07 Flow assay with at least one electrically-actuated fluid flow control valve and related methods
PCT/US2018/026195 WO2018187535A1 (en) 2017-04-07 2018-04-05 Flow assay with at least one electrically-actuated fluid flow control valve and related methods

Publications (2)

Publication Number Publication Date
EP3607324A1 EP3607324A1 (en) 2020-02-12
EP3607324A4 true EP3607324A4 (en) 2021-01-13

Family

ID=63712961

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18781906.5A Withdrawn EP3607324A4 (en) 2017-04-07 2018-04-05 Flow assay with at least one electrically-actuated fluid flow control valve and related methods

Country Status (4)

Country Link
EP (1) EP3607324A4 (en)
CN (1) CN110662965B (en)
TW (1) TW201903410A (en)
WO (1) WO2018187535A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2617194A (en) * 2022-04-01 2023-10-04 Mint Diagnostics Ltd Microfluidic collection and test

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010102279A1 (en) * 2009-03-06 2010-09-10 President And Fellows Of Harvard College Microfluidic, electromechanical devices
WO2015058292A1 (en) * 2013-10-23 2015-04-30 The Governing Council Of The University Of Toronto Printed digital microfluidic devices methods of use and manufacture thereof
US20160084796A1 (en) * 2014-09-19 2016-03-24 Tokitae Llc Flow assay with at least one electrically-actuated fluid flow control valve and related methods

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1010327C2 (en) * 1998-10-15 2000-04-18 Univ Twente Apparatus and method for controlling a liquid flow.
US20020189947A1 (en) * 2001-06-13 2002-12-19 Eksigent Technologies Llp Electroosmotic flow controller
US7364647B2 (en) * 2002-07-17 2008-04-29 Eksigent Technologies Llc Laminated flow device
JP5277372B2 (en) * 2007-09-10 2013-08-28 理想科学工業株式会社 Liquid feeding device and liquid feeding control method
JP5383138B2 (en) * 2008-10-01 2014-01-08 シャープ株式会社 Liquid feeding structure with electrowetting valve, microanalysis chip and analyzer using the same
JP5429774B2 (en) * 2008-10-01 2014-02-26 シャープ株式会社 Liquid feeding structure, micro-analysis chip and analyzer using the same
EP2703817A1 (en) * 2012-09-03 2014-03-05 Celoxio AB On chip control of fluids using electrodes
CN102980930B (en) * 2012-12-17 2014-11-05 江苏科技大学 Preparation method of electric wettability electrode

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010102279A1 (en) * 2009-03-06 2010-09-10 President And Fellows Of Harvard College Microfluidic, electromechanical devices
WO2015058292A1 (en) * 2013-10-23 2015-04-30 The Governing Council Of The University Of Toronto Printed digital microfluidic devices methods of use and manufacture thereof
US20160084796A1 (en) * 2014-09-19 2016-03-24 Tokitae Llc Flow assay with at least one electrically-actuated fluid flow control valve and related methods

Also Published As

Publication number Publication date
CN110662965B (en) 2023-09-12
CN110662965A (en) 2020-01-07
EP3607324A1 (en) 2020-02-12
WO2018187535A1 (en) 2018-10-11
TW201903410A (en) 2019-01-16

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