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EP3367151A4 - Structured illumination microscope, observation method, and microscope control program - Google Patents

Structured illumination microscope, observation method, and microscope control program Download PDF

Info

Publication number
EP3367151A4
EP3367151A4 EP15906628.1A EP15906628A EP3367151A4 EP 3367151 A4 EP3367151 A4 EP 3367151A4 EP 15906628 A EP15906628 A EP 15906628A EP 3367151 A4 EP3367151 A4 EP 3367151A4
Authority
EP
European Patent Office
Prior art keywords
microscope
control program
observation method
structured illumination
microscope control
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP15906628.1A
Other languages
German (de)
French (fr)
Other versions
EP3367151A1 (en
EP3367151B1 (en
Inventor
Hisao Osawa
Fumihiro DAKE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nikon Corp
Original Assignee
Nikon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nikon Corp filed Critical Nikon Corp
Publication of EP3367151A1 publication Critical patent/EP3367151A1/en
Publication of EP3367151A4 publication Critical patent/EP3367151A4/en
Application granted granted Critical
Publication of EP3367151B1 publication Critical patent/EP3367151B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/0092—Polarisation microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G02B21/08—Condensers
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G02B21/08—Condensers
    • G02B21/082—Condensers for incident illumination only
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/58—Optics for apodization or superresolution; Optical synthetic aperture systems

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Multimedia (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Microscoopes, Condenser (AREA)
  • Liquid Crystal (AREA)
EP15906628.1A 2015-10-19 2015-10-19 Structured illumination microscope, observation method, and microscope control program Active EP3367151B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2015/079422 WO2017068620A1 (en) 2015-10-19 2015-10-19 Structured illumination microscope, observation method, and microscope control program

Publications (3)

Publication Number Publication Date
EP3367151A1 EP3367151A1 (en) 2018-08-29
EP3367151A4 true EP3367151A4 (en) 2019-07-24
EP3367151B1 EP3367151B1 (en) 2024-07-17

Family

ID=58557120

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15906628.1A Active EP3367151B1 (en) 2015-10-19 2015-10-19 Structured illumination microscope, observation method, and microscope control program

Country Status (4)

Country Link
US (1) US10900900B2 (en)
EP (1) EP3367151B1 (en)
JP (1) JP6645506B2 (en)
WO (1) WO2017068620A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018185489A1 (en) 2017-04-07 2018-10-11 Universitetet I Tromsø - Norges Arktiske Universitet Optical component for generating a periodic light pattern
KR101934956B1 (en) * 2017-10-18 2019-03-18 고려대학교 산학협력단 Apparatus and method for single-molecule localization with structured illumination and phase detection
DE102018108657B4 (en) 2018-04-12 2024-03-28 Jenoptik Optical Systems Gmbh Device for recording at least one microscopic image and method for recording a microscopic image
ES2753927A1 (en) * 2018-10-10 2020-04-14 Consejo Superior Investigacion PARTICLE IDENTIFICATION SYSTEM AND METHOD IN TRANSMISSION MICROSCOPY (Machine-translation by Google Translate, not legally binding)
EP3948237B1 (en) * 2019-04-02 2024-05-01 Thermo Electron Scientific Instruments LLC Enhanced sample imaging using structured illumination microscopy
KR102473456B1 (en) * 2019-08-19 2022-12-07 부산대학교 산학협력단 High-resolution structured illumination microscopy system for imaging nano patterns fabricated on cylinerical mold and operating method thereof
CN113281941B (en) * 2021-04-29 2022-07-12 深圳市华星光电半导体显示技术有限公司 Display panel

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015087960A1 (en) * 2013-12-12 2015-06-18 株式会社ニコン Structured illumination microscope, structured illumination method and program

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5748164A (en) * 1994-12-22 1998-05-05 Displaytech, Inc. Active matrix liquid crystal image generator
US6525709B1 (en) * 1997-10-17 2003-02-25 Displaytech, Inc. Miniature display apparatus and method
JP2000292772A (en) * 1999-04-08 2000-10-20 Sony Corp Method of driving liquid crystal device and liquid crystal device
JP4801239B2 (en) * 1999-05-14 2011-10-26 株式会社半導体エネルギー研究所 Liquid crystal display
US6545656B1 (en) 1999-05-14 2003-04-08 Semiconductor Energy Laboratory Co., Ltd. Liquid crystal display device in which a black display is performed by a reset signal during one sub-frame
JP2006145591A (en) * 2004-11-16 2006-06-08 Toshiba Corp Image forming apparatus
WO2006109448A1 (en) 2005-03-30 2006-10-19 Nikon Corporation Image forming method and microscope device
JP4335904B2 (en) * 2006-12-07 2009-09-30 エルジー ディスプレイ カンパニー リミテッド Liquid crystal display
JP2009116173A (en) 2007-11-08 2009-05-28 Dainippon Printing Co Ltd Driving method of liquid crystal display device
JP5301223B2 (en) 2008-09-11 2013-09-25 シチズンファインテックミヨタ株式会社 Ferroelectric liquid crystal display device
JP5578781B2 (en) * 2008-11-11 2014-08-27 治雄 岡村 A tool to make a hole in cardboard and pass a string through
WO2014013720A1 (en) 2012-07-19 2014-01-23 株式会社ニコン Structured illumination microscope device
JP6194710B2 (en) * 2013-09-11 2017-09-13 株式会社ニコン Structured illumination device and structured illumination microscope device

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015087960A1 (en) * 2013-12-12 2015-06-18 株式会社ニコン Structured illumination microscope, structured illumination method and program
US20160320600A1 (en) * 2013-12-12 2016-11-03 Nikon Corporation Structured illumination microscope, structured illumination method, and program

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HUI-WEN LU-WALTHER ET AL: "fastSIM: a practical implementation of fast structured illumination microscopy", METHODS AND APPLICATIONS IN FLUORESCENCE, vol. 3, no. 1, 16 January 2015 (2015-01-16), pages 014001, XP055595705, DOI: 10.1088/2050-6120/3/1/014001 *
RONNY FÖRSTER ET AL: "Simple structured illumination microscope setup with high acquisition speed by using a spatial light modulator", OPTICS EXPRESS, vol. 22, no. 17, 19 August 2014 (2014-08-19), pages 20663, XP055595728, DOI: 10.1364/OE.22.020663 *
See also references of WO2017068620A1 *

Also Published As

Publication number Publication date
EP3367151A1 (en) 2018-08-29
JPWO2017068620A1 (en) 2018-08-02
JP6645506B2 (en) 2020-02-14
WO2017068620A1 (en) 2017-04-27
US20180238803A1 (en) 2018-08-23
US10900900B2 (en) 2021-01-26
EP3367151B1 (en) 2024-07-17

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