EP2780029A4 - Formulations orales de leptine et leurs utilisations - Google Patents

Formulations orales de leptine et leurs utilisations

Info

Publication number: EP2780029A4
Authority: EP; European Patent Office
Prior art keywords: oral; leptin formulations; leptin; formulations; oral leptin
Prior art date: 2011-11-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP11875859.8A

Other languages

German (de)

English (en)

Other versions

EP2780029A1 (fr

Inventor

Moise Bendayan

Phillippe Cammisotto

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Universite de Montreal

Original Assignee

Universite de Montreal

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-11-18

Filing date

2011-11-18

Publication date

2015-06-24

2011-11-18 Application filed by Universite de Montreal filed Critical Universite de Montreal

2014-09-24 Publication of EP2780029A1 publication Critical patent/EP2780029A1/fr

2015-06-24 Publication of EP2780029A4 publication Critical patent/EP2780029A4/fr

Status Withdrawn legal-status Critical Current

Links

102000016267 Leptin Human genes 0.000 title 1
108010092277 Leptin Proteins 0.000 title 1
238000009472 formulation Methods 0.000 title 1
NRYBAZVQPHGZNS-ZSOCWYAHSA-N leptin Chemical compound O=C([C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(C)C)CCSC)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CS)C(O)=O NRYBAZVQPHGZNS-ZSOCWYAHSA-N 0.000 title 1
229940039781 leptin Drugs 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2207—Gastrins; Cholecystokinins [CCK]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2235—Secretins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2264—Obesity-gene products, e.g. leptin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Genetics & Genomics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Mycology (AREA)
Nutrition Science (AREA)
Food Science & Technology (AREA)
Polymers & Plastics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

EP11875859.8A 2011-11-18 2011-11-18 Formulations orales de leptine et leurs utilisations Withdrawn EP2780029A4 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/CA2011/050720 WO2013071396A1 (fr)	2011-11-18	2011-11-18	Formulations orales de leptine et leurs utilisations

Publications (2)

Publication Number	Publication Date
EP2780029A1 EP2780029A1 (fr)	2014-09-24
EP2780029A4 true EP2780029A4 (fr)	2015-06-24

Family

ID=48428867

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP11875859.8A Withdrawn EP2780029A4 (fr)	2011-11-18	2011-11-18	Formulations orales de leptine et leurs utilisations

Country Status (3)

Country	Link
EP (1)	EP2780029A4 (fr)
CA (1)	CA2855545A1 (fr)
WO (1)	WO2013071396A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2017532292A (ja) *	2014-08-11	2017-11-02	オルバニーメディカルカレッジ	ミリストイル化レプチン関連ペプチド及びその使用
AU2022244505A1 (en) *	2021-03-23	2023-02-09	Kashiv Biosciences, Llc	An extraction process of pancrelipase and evaluation threof
CN115463094B (zh) *	2021-06-10	2023-07-04	北京微著新材科技有限公司	一种口服放疗防护剂及其制备方法和应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060045869A1 (en) *	2004-08-25	2006-03-02	Aegis Therapeutics Llc	Absorption enhancers for drug administration
WO2006133333A2 (fr) *	2005-06-07	2006-12-14	The Rockefeller University	Stimulation de proliferation de lymphocytes pancreatiques b
WO2007109354A2 (fr) *	2006-03-21	2007-09-27	Amylin Pharmaceuticals, Inc.	Conjugués inhibiteur de peptidase-peptide et procédés d'utilisation de ceux-ci

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8268791B2 (en) *	2004-08-25	2012-09-18	Aegis Therapeutics, Llc.	Alkylglycoside compositions for drug administration
EP2470197A4 (fr) *	2009-08-24	2013-03-13	Aegis Therapeutics Llc	Composition pour l absorption et l action prolongée de peptides liés à la leptine

2011
- 2011-11-18 WO PCT/CA2011/050720 patent/WO2013071396A1/fr active Application Filing
- 2011-11-18 EP EP11875859.8A patent/EP2780029A4/fr not_active Withdrawn
- 2011-11-18 CA CA2855545A patent/CA2855545A1/fr not_active Abandoned

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060045869A1 (en) *	2004-08-25	2006-03-02	Aegis Therapeutics Llc	Absorption enhancers for drug administration
WO2006133333A2 (fr) *	2005-06-07	2006-12-14	The Rockefeller University	Stimulation de proliferation de lymphocytes pancreatiques b
WO2007109354A2 (fr) *	2006-03-21	2007-09-27	Amylin Pharmaceuticals, Inc.	Conjugués inhibiteur de peptidase-peptide et procédés d'utilisation de ceux-ci

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2013071396A1 *

Also Published As

Publication number	Publication date
EP2780029A1 (fr)	2014-09-24
WO2013071396A1 (fr)	2013-05-23
CA2855545A1 (fr)	2013-05-23

Publication	Publication Date	Title
TWI559936B (en)	2016-12-01	Oral care compositions
HK1183802A1 (en)	2014-01-10	Therapeutic oral composition
ZA201206666B (en)	2016-09-28	Oral care composition
HUE033071T2 (hu)	2017-11-28	Vakcinakészítmények
SG11201401056SA (en)	2014-04-28	Oral care compositions
AU2012398397A8 (en)	2015-07-02	Oral care composition
ZA201206301B (en)	2015-10-28	Oral care composition
ZA201205804B (en)	2015-03-25	Oral care compositions
PT2605757E (pt)	2015-10-19	Formulações à base de nalbufina e suas utilizações
HK1203432A1 (en)	2015-10-30	Oral care compositions
ZA201206068B (en)	2015-04-29	Oral care compositions
HK1203402A1 (en)	2015-10-30	Oral care compositions
PL2555829T3 (pl)	2017-05-31	Kompozycje do pielęgnacji jamy ustnej
HK1183228A1 (zh)	2013-12-20	口服藥物治療方法和組合物
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HK1200705A1 (en)	2015-08-14	Oral care compositions
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HK1198137A1 (en)	2015-03-13	Disinfecting formulations and uses thereof
EP2734194A4 (fr)	2015-04-22	Formulations de soin buccal
EP2780029A4 (fr)	2015-06-24	Formulations orales de leptine et leurs utilisations
HK1203386A1 (en)	2015-10-30	Oral care compositions
EP2533762A4 (fr)	2015-01-07	Formulations de rétinol et procédés pour leur utilisation
EP2531180A4 (fr)	2014-04-02	Composition complexe orale comprenant la pseudoéphédrine et la lévocétirizine
HK1200100A1 (en)	2015-07-31	Oral care composition

Legal Events

Date	Code	Title	Description
2014-08-22	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2014-09-24	17P	Request for examination filed	Effective date: 20140527
2014-09-24	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2015-02-25	DAX	Request for extension of the european patent (deleted)
2015-06-24	RA4	Supplementary search report drawn up and despatched (corrected)	Effective date: 20150522
2015-06-24	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 31/56 20060101ALI20150518BHEP Ipc: A61K 38/05 20060101ALI20150518BHEP Ipc: A23L 1/30 20060101ALI20150518BHEP Ipc: C07K 14/81 20060101ALI20150518BHEP Ipc: A61K 9/00 20060101ALI20150518BHEP Ipc: C07K 14/575 20060101ALI20150518BHEP Ipc: A61P 3/00 20060101ALI20150518BHEP Ipc: A61K 38/57 20060101ALI20150518BHEP Ipc: A61K 38/22 20060101AFI20150518BHEP Ipc: A61K 31/575 20060101ALI20150518BHEP Ipc: A61K 45/06 20060101ALI20150518BHEP Ipc: A61K 31/203 20060101ALI20150518BHEP Ipc: A61K 38/28 20060101ALI20150518BHEP Ipc: A61K 31/198 20060101ALI20150518BHEP Ipc: C07K 7/02 20060101ALI20150518BHEP
2016-06-17	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2016-07-20	18D	Application deemed to be withdrawn	Effective date: 20151222