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EP2195022A4 - Compositions comprenant un antigène, un composé amphipathique et un support hydrophobe, et leurs utilisations - Google Patents

Compositions comprenant un antigène, un composé amphipathique et un support hydrophobe, et leurs utilisations

Info

Publication number
EP2195022A4
EP2195022A4 EP08800418A EP08800418A EP2195022A4 EP 2195022 A4 EP2195022 A4 EP 2195022A4 EP 08800418 A EP08800418 A EP 08800418A EP 08800418 A EP08800418 A EP 08800418A EP 2195022 A4 EP2195022 A4 EP 2195022A4
Authority
EP
European Patent Office
Prior art keywords
antigen
compositions
hydrophobic carrier
amphipathic compound
amphipathic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08800418A
Other languages
German (de)
English (en)
Other versions
EP2195022A1 (fr
Inventor
Marc Mansour
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunovaccine Technologies Inc
Original Assignee
Immunovaccine Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunovaccine Technologies Inc filed Critical Immunovaccine Technologies Inc
Publication of EP2195022A1 publication Critical patent/EP2195022A1/fr
Publication of EP2195022A4 publication Critical patent/EP2195022A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Addiction (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biophysics (AREA)
  • Psychiatry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Zoology (AREA)
EP08800418A 2007-10-03 2008-10-02 Compositions comprenant un antigène, un composé amphipathique et un support hydrophobe, et leurs utilisations Withdrawn EP2195022A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97719707P 2007-10-03 2007-10-03
PCT/CA2008/001747 WO2009043165A1 (fr) 2007-10-03 2008-10-02 Compositions comprenant un antigène, un composé amphipathique et un support hydrophobe, et leurs utilisations

Publications (2)

Publication Number Publication Date
EP2195022A1 EP2195022A1 (fr) 2010-06-16
EP2195022A4 true EP2195022A4 (fr) 2012-08-01

Family

ID=40525804

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08800418A Withdrawn EP2195022A4 (fr) 2007-10-03 2008-10-02 Compositions comprenant un antigène, un composé amphipathique et un support hydrophobe, et leurs utilisations

Country Status (7)

Country Link
EP (1) EP2195022A4 (fr)
JP (1) JP5591705B2 (fr)
CN (1) CN101815529B (fr)
AU (1) AU2008307042B2 (fr)
BR (1) BRPI0817484B1 (fr)
CA (1) CA2700828C (fr)
WO (1) WO2009043165A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5731198B2 (ja) 2007-09-27 2015-06-10 イムノバクシーン・テクノロジーズ・インコーポレイテッドImmunovaccine Technologies Inc. インビボでのポリヌクレオチドの送達のための連続疎水相を含む担体におけるリポソームの使用
CA2723918C (fr) 2008-06-05 2018-01-09 Immunovaccine Technologies Inc. Compositions contenant des liposomes, un antigene, un polynucleotide et un transporteur comprenant une phase continue d'une substance hydrophobe
CA2850857C (fr) * 2011-10-06 2022-07-26 Immunovaccine Technologies Inc. Compositions liposomales comprenant un adjuvant qui active ou accroit l'activite de tlr2 et utilisations associees
ES2886999T3 (es) 2013-03-27 2021-12-21 Immunovaccine Technologies Inc Procedimiento para mejorar la eficacia de una vacuna de survivina en el tratamiento de cáncer
CN107531736B (zh) 2015-01-06 2022-04-15 免疫疫苗科技公司 脂质a模拟物、其制备方法和用途
CN105044328A (zh) * 2015-05-28 2015-11-11 首都医科大学附属北京佑安医院 Elispot预包被培养板及其制备方法
AU2016355926A1 (en) * 2015-11-18 2018-05-31 Immunovaccine Technologies Inc. Adjuvanting systems and water-free vaccine compositions comprising a polyi:C polynucleotide adjuvant and a lipid-based adjuvant
CA3022924A1 (fr) * 2016-05-04 2017-11-09 Immunovaccine Technologies Inc. Compositions de vaccin comprenant un compose amphipathique, un neoantigene et un support hydrophobe, et leurs procedes d'utilisation
AU2016425290A1 (en) * 2016-09-27 2019-04-11 Immunovaccine Technologies Inc. Methods of using low dose volume B-cell epitope compositions for inducing an antibody immune response in human subjects
US20210147544A1 (en) * 2018-03-20 2021-05-20 Immunovaccine Technologies Inc. Methods and compositions for targeted delivery of active agents and immunomodulatory agents to lymph nodes
CA3207998A1 (fr) * 2021-02-16 2022-08-25 Geoffrey M. Lynn Nanoparticules auto-assemblees a base de peptides amphiphiles

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0640347A1 (fr) * 1992-03-03 1995-03-01 Daiichi Pharmaceutical Co., Ltd. Vaccin oral
WO1996014871A1 (fr) * 1994-11-15 1996-05-23 Cortecs Limited Compositions immunogenes
US5736141A (en) * 1992-06-05 1998-04-07 Dalhousie University Method to prevent fertilization in mammals by administering a single dose of zona pellucida derived antigens, liposome and Freund's adjuvant
WO1998053799A2 (fr) * 1997-05-28 1998-12-03 Jenner Biotherapies, Inc. Compositions immunogenes
WO2002038175A1 (fr) * 2000-11-07 2002-05-16 Immunovaccine Technologies Inc. Vaccins a reponse immunitaire accrue et leurs procedes de preparation
WO2007041832A1 (fr) * 2005-10-07 2007-04-19 Immunovaccine Technologies Inc. Utilisation de liposomes dans un vehicule contenant une phase hydrophobe continue en tant que vehicule de traitement du cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6565885B1 (en) * 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6956021B1 (en) * 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0640347A1 (fr) * 1992-03-03 1995-03-01 Daiichi Pharmaceutical Co., Ltd. Vaccin oral
US5736141A (en) * 1992-06-05 1998-04-07 Dalhousie University Method to prevent fertilization in mammals by administering a single dose of zona pellucida derived antigens, liposome and Freund's adjuvant
WO1996014871A1 (fr) * 1994-11-15 1996-05-23 Cortecs Limited Compositions immunogenes
WO1998053799A2 (fr) * 1997-05-28 1998-12-03 Jenner Biotherapies, Inc. Compositions immunogenes
WO2002038175A1 (fr) * 2000-11-07 2002-05-16 Immunovaccine Technologies Inc. Vaccins a reponse immunitaire accrue et leurs procedes de preparation
WO2007041832A1 (fr) * 2005-10-07 2007-04-19 Immunovaccine Technologies Inc. Utilisation de liposomes dans un vehicule contenant une phase hydrophobe continue en tant que vehicule de traitement du cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HENRY D. STONE: "Newcastle Disease Oil Emulsion Vavvines Prepared with Animal, Vegetable, ans Synthetic Oils", AVIAN DISEASES, vol. 41, 1997, pages 591 - 597, XP008152979 *
See also references of WO2009043165A1 *

Also Published As

Publication number Publication date
JP2010540570A (ja) 2010-12-24
EP2195022A1 (fr) 2010-06-16
JP5591705B2 (ja) 2014-09-17
CN101815529A (zh) 2010-08-25
CA2700828C (fr) 2017-01-24
CA2700828A1 (fr) 2009-04-09
WO2009043165A1 (fr) 2009-04-09
BRPI0817484B1 (pt) 2021-08-17
BRPI0817484A2 (pt) 2015-03-24
AU2008307042B2 (en) 2014-01-30
AU2008307042A1 (en) 2009-04-09
CN101815529B (zh) 2016-03-09

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Legal Events

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A4 Supplementary search report drawn up and despatched

Effective date: 20120628

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Ipc: A61K 47/24 20060101ALI20120622BHEP

Ipc: A61K 47/48 20060101ALI20120622BHEP

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