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EP1978988A4 - REGULATION OF COMMUNICATING JUNCTIONS USING PEPTIDES - Google Patents

REGULATION OF COMMUNICATING JUNCTIONS USING PEPTIDES

Info

Publication number
EP1978988A4
EP1978988A4 EP07718080A EP07718080A EP1978988A4 EP 1978988 A4 EP1978988 A4 EP 1978988A4 EP 07718080 A EP07718080 A EP 07718080A EP 07718080 A EP07718080 A EP 07718080A EP 1978988 A4 EP1978988 A4 EP 1978988A4
Authority
EP
European Patent Office
Prior art keywords
peptides
regulation
communicating junctions
junctions
communicating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07718080A
Other languages
German (de)
French (fr)
Other versions
EP1978988A2 (en
Inventor
Mario Delmar
Steven M Taffet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of the State University of New York
Original Assignee
Research Foundation of the State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of the State University of New York filed Critical Research Foundation of the State University of New York
Publication of EP1978988A2 publication Critical patent/EP1978988A2/en
Publication of EP1978988A4 publication Critical patent/EP1978988A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP07718080A 2006-01-13 2007-01-16 REGULATION OF COMMUNICATING JUNCTIONS USING PEPTIDES Withdrawn EP1978988A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75888606P 2006-01-13 2006-01-13
PCT/US2007/060584 WO2007084895A2 (en) 2006-01-13 2007-01-16 Peptide-based regulation of gap junctions

Publications (2)

Publication Number Publication Date
EP1978988A2 EP1978988A2 (en) 2008-10-15
EP1978988A4 true EP1978988A4 (en) 2009-11-04

Family

ID=38288369

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07718080A Withdrawn EP1978988A4 (en) 2006-01-13 2007-01-16 REGULATION OF COMMUNICATING JUNCTIONS USING PEPTIDES

Country Status (2)

Country Link
EP (1) EP1978988A4 (en)
WO (1) WO2007084895A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090075291A1 (en) * 2006-01-13 2009-03-19 The Research Foundation Of State University Of New York Peptide-based regulation of gap junctions
EP2190455A4 (en) 2007-09-07 2010-11-24 Australian Meat & Live Stock MEDIUM WITH ANGIOGENIC AND WOUND HEALING ACTIVITY
EP2260859A1 (en) * 2009-06-12 2010-12-15 Zealand Pharma A/S Compounds acting as peptide gap junction modulators and their uses

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009012224A2 (en) * 2007-07-13 2009-01-22 The Research Foundation Of State University Of New York Peptide-based regulation of gap junctions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6551795B1 (en) * 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
JP2000026315A (en) * 1998-07-09 2000-01-25 Dai Ichi Seiyaku Co Ltd Evaluation of calcium channel activator
US20070264241A1 (en) * 2004-02-25 2007-11-15 Ekstrom Tomas J Compounds for Enhanced Cancer Therapy

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009012224A2 (en) * 2007-07-13 2009-01-22 The Research Foundation Of State University Of New York Peptide-based regulation of gap junctions

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
COOMBS W ET AL: "A peptide-based strategy to modify Cx43CT structure and Cx43 channel function", MOLECULAR BIOLOGY OF THE CELL, BETHESDA, MD, US, vol. 15, no. Suppl. S, 1 November 2004 (2004-11-01), pages 308A - 309A, XP008110588, ISSN: 1059-1524 *
DUFFY HEATHER S ET AL: "pH-dependent intramolecular binding and structure involving Cx43 cytoplasmic domains", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM, US, vol. 277, no. 39, 27 September 2002 (2002-09-27), pages 36706 - 36714, XP009108338, ISSN: 0021-9258 *
KWAK BRENDA R ET AL: "Selective inhibition of gap junction channel activity by synthetic peptides", JOURNAL OF PHYSIOLOGY, WILEY-BLACKWELL PUBLISHING LTD, GB, vol. 516, no. 3, 1 May 1999 (1999-05-01), pages 679 - 685, XP009108312, ISSN: 0022-3751 *
SHIBAYAMA JUNKO ET AL: "Identification of a novel peptide that interferes with the chemical regulation of connexin43", CIRCULATION RESEARCH, GRUNE AND STRATTON, BALTIMORE, US, vol. 98, no. 11, 1 June 2006 (2006-06-01), pages 1365 - 1372, XP009115918, ISSN: 0009-7330 *
TAFFET ET AL: "Manipulation of gap junction proteins: effect on cellular coupling and impulse propagation", JOURNAL OF ELECTROCARDIOLOGY, ELSEVIER SCIENCE, XX, vol. 38, no. 4, 1 October 2005 (2005-10-01), pages 51, XP005110123, ISSN: 0022-0736 *

Also Published As

Publication number Publication date
WO2007084895A3 (en) 2008-08-14
EP1978988A2 (en) 2008-10-15
WO2007084895A2 (en) 2007-07-26

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20080717

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK RS

A4 Supplementary search report drawn up and despatched

Effective date: 20091001

RIC1 Information provided on ipc code assigned before grant

Ipc: C07K 7/08 20060101ALI20090925BHEP

Ipc: A61K 38/10 20060101AFI20070904BHEP

17Q First examination report despatched

Effective date: 20100708

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20110119