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EP1797818A3 - Method and system for tomographic imaging using fluorescent proteins - Google Patents

Method and system for tomographic imaging using fluorescent proteins Download PDF

Info

Publication number
EP1797818A3
EP1797818A3 EP07075199A EP07075199A EP1797818A3 EP 1797818 A3 EP1797818 A3 EP 1797818A3 EP 07075199 A EP07075199 A EP 07075199A EP 07075199 A EP07075199 A EP 07075199A EP 1797818 A3 EP1797818 A3 EP 1797818A3
Authority
EP
European Patent Office
Prior art keywords
fluorescent proteins
light
tomographic imaging
laser
scanner
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07075199A
Other languages
German (de)
French (fr)
Other versions
EP1797818A2 (en
Inventor
Vasilis Ntziachristos
Jorge Ripoll
Giannis Zacharakis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Priority claimed from EP05725039A external-priority patent/EP1727460A2/en
Publication of EP1797818A2 publication Critical patent/EP1797818A2/en
Publication of EP1797818A3 publication Critical patent/EP1797818A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Light from a laser (402) is reflected by an optical scanner (412) to a body (416) containing fluorescent proteins from which light generated by fluorescence passes to a CCD detector (422) for analysis in an image processing computer (424). The scanner (412) has selectively movable components for directing the laser light along a plurality of different light paths to the body (416), thereby selectively moving the apparent source of the laser light.
EP07075199A 2004-03-11 2005-03-10 Method and system for tomographic imaging using fluorescent proteins Withdrawn EP1797818A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US55224904P 2004-03-11 2004-03-11
US57069004P 2004-05-13 2004-05-13
EP05725039A EP1727460A2 (en) 2004-03-11 2005-03-10 Method and system for tomographic imaging using fluorescent proteins

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP05725039A Division EP1727460A2 (en) 2004-03-11 2005-03-10 Method and system for tomographic imaging using fluorescent proteins

Publications (2)

Publication Number Publication Date
EP1797818A2 EP1797818A2 (en) 2007-06-20
EP1797818A3 true EP1797818A3 (en) 2008-02-13

Family

ID=38039119

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07075199A Withdrawn EP1797818A3 (en) 2004-03-11 2005-03-10 Method and system for tomographic imaging using fluorescent proteins

Country Status (1)

Country Link
EP (1) EP1797818A3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011156810A2 (en) 2010-06-11 2011-12-15 The Florida International University Board Of Trustees Second generation hand-held optical imager
EP2800511A4 (en) * 2012-01-06 2015-09-09 Florida Int Univ Board Trustees Near-infrared (nir) optical scanner
US10258242B2 (en) 2014-01-06 2019-04-16 The Florida International University Board Of Trustees Near-infrared optical imaging system for hemodynamic imaging, pulse monitoring, and mapping spatio-temporal features
US11141064B2 (en) * 2017-07-19 2021-10-12 Perkinelmer Health Sciences, Inc. Systems and methods for rapid wide field illumination scanning for in vivo small animal fluorescence tomographic imaging
US11153499B2 (en) 2017-07-19 2021-10-19 Perkinelmer Health Sciences, Inc. Rapid, high dynamic range image acquisition with a charge-coupled device (CCD) camera

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0336208A1 (en) * 1988-03-29 1989-10-11 Shimadzu Corporation Computed tomograph
WO1996026431A1 (en) * 1995-02-21 1996-08-29 Massachusetts Institute Of Technology Optical imaging using time gated scattered light
US5787887A (en) * 1993-11-24 1998-08-04 Siemens Aktiengesellschaft Apparatus for tissue examination using bidirectional transirradiation with light
US20010037811A1 (en) * 2000-02-04 2001-11-08 Juergen Beuthan Method and apparatus for arthritis diagnosis
WO2002041760A2 (en) * 2000-11-27 2002-05-30 The General Hospital Fluorescence-mediated molecular tomography
WO2003077750A1 (en) * 2002-03-13 2003-09-25 Tufts University Optical imaging and oximetry of tissue
WO2004008952A1 (en) * 2002-07-18 2004-01-29 Mauna Kea Technologies Method and equipment for fiber optic high-resolution, in particular confocal, fluorescence imaging
WO2004072906A1 (en) * 2003-02-05 2004-08-26 The General Hospital Corporation Method and system for free space optical tomography of diffuse media

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0336208A1 (en) * 1988-03-29 1989-10-11 Shimadzu Corporation Computed tomograph
US5787887A (en) * 1993-11-24 1998-08-04 Siemens Aktiengesellschaft Apparatus for tissue examination using bidirectional transirradiation with light
WO1996026431A1 (en) * 1995-02-21 1996-08-29 Massachusetts Institute Of Technology Optical imaging using time gated scattered light
US20010037811A1 (en) * 2000-02-04 2001-11-08 Juergen Beuthan Method and apparatus for arthritis diagnosis
WO2002041760A2 (en) * 2000-11-27 2002-05-30 The General Hospital Fluorescence-mediated molecular tomography
WO2003077750A1 (en) * 2002-03-13 2003-09-25 Tufts University Optical imaging and oximetry of tissue
WO2004008952A1 (en) * 2002-07-18 2004-01-29 Mauna Kea Technologies Method and equipment for fiber optic high-resolution, in particular confocal, fluorescence imaging
WO2004072906A1 (en) * 2003-02-05 2004-08-26 The General Hospital Corporation Method and system for free space optical tomography of diffuse media

Also Published As

Publication number Publication date
EP1797818A2 (en) 2007-06-20

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