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EP1685237A4 - Novel multipotent stem cells and use thereof - Google Patents

Novel multipotent stem cells and use thereof

Info

Publication number
EP1685237A4
EP1685237A4 EP04796882A EP04796882A EP1685237A4 EP 1685237 A4 EP1685237 A4 EP 1685237A4 EP 04796882 A EP04796882 A EP 04796882A EP 04796882 A EP04796882 A EP 04796882A EP 1685237 A4 EP1685237 A4 EP 1685237A4
Authority
EP
European Patent Office
Prior art keywords
stem cells
multipotent stem
novel multipotent
novel
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04796882A
Other languages
German (de)
French (fr)
Other versions
EP1685237A2 (en
Inventor
Young-Sup Yoon
Douglas W Losordo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Caritas St Elizabeth Medical Center of Boston
St Elizabeths Medical Center of Boston Inc
Original Assignee
Caritas St Elizabeth Medical Center of Boston
St Elizabeths Medical Center of Boston Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Caritas St Elizabeth Medical Center of Boston, St Elizabeths Medical Center of Boston Inc filed Critical Caritas St Elizabeth Medical Center of Boston
Publication of EP1685237A2 publication Critical patent/EP1685237A2/en
Publication of EP1685237A4 publication Critical patent/EP1685237A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP04796882A 2003-10-28 2004-10-28 Novel multipotent stem cells and use thereof Withdrawn EP1685237A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51532003P 2003-10-28 2003-10-28
PCT/US2004/036298 WO2005042723A2 (en) 2003-10-28 2004-10-28 Novel multipotent stem cells and use thereof

Publications (2)

Publication Number Publication Date
EP1685237A2 EP1685237A2 (en) 2006-08-02
EP1685237A4 true EP1685237A4 (en) 2007-12-26

Family

ID=34549391

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04796882A Withdrawn EP1685237A4 (en) 2003-10-28 2004-10-28 Novel multipotent stem cells and use thereof

Country Status (7)

Country Link
EP (1) EP1685237A4 (en)
JP (1) JP2007519397A (en)
KR (1) KR20070007030A (en)
CN (1) CN101072867A (en)
AU (1) AU2004286322A1 (en)
CA (1) CA2543794A1 (en)
WO (1) WO2005042723A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007047963A2 (en) * 2005-10-20 2007-04-26 Caritas St. Elizabeth Medical Center Of Boston, Inc. Use of bone-marrow derived stem cells to treat ischemia
US9155762B2 (en) 2005-12-08 2015-10-13 University Of Louisville Research Foundation, Inc. Uses and isolation of stem cells from bone marrow
PL2535403T3 (en) * 2005-12-08 2019-10-31 Univ Louisville Res Found Inc Very small embryonic-like (VSEL) stem cells and methods of isolating and using the same
WO2007127408A2 (en) * 2006-04-28 2007-11-08 Tulane University Health Sciences Center Methods for treating diabetes
US20100260725A1 (en) * 2007-09-24 2010-10-14 Mohapatra Shyam S Materials and Methods for Treating Allergic and Inflammatory Conditions
NZ709124A (en) * 2009-10-30 2017-06-30 Univ North Carolina Chapel Hill Multipotent stem cells from the extrahepatic biliary tree and methods of isolating same
US11312940B2 (en) 2015-08-31 2022-04-26 University Of Louisville Research Foundation, Inc. Progenitor cells and methods for preparing and using the same
EP3423568A4 (en) 2016-03-04 2019-11-13 University Of Louisville Research Foundation, Inc. Methods and compositions for ex vivo expansion of very small embryonic-like stem cells (vsels)
CN115369077B (en) * 2022-07-29 2023-07-18 佛山市中科律动生物科技有限公司 MEFLC cell strain, construction method and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387369B1 (en) * 1997-07-14 2002-05-14 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
US6291240B1 (en) * 1998-01-29 2001-09-18 Advanced Tissue Sciences, Inc. Cells or tissues with increased protein factors and methods of making and using same
US6328762B1 (en) * 1999-04-27 2001-12-11 Sulzer Biologics, Inc. Prosthetic grafts

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CHO HYUN-JAI ET AL: "Bone marrow-derived stem cell therapy in ischemic heart disease", REGENERATIVE MEDICINE, vol. 1, no. 3, May 2006 (2006-05-01), pages 337 - 345, XP001536397, ISSN: 1746-0751 *
JACKSON K A ET AL: "Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells", JOURNAL OF CLINICAL INVESTIGATION, NEW YORK, NY, US, vol. 107, no. 11, June 2001 (2001-06-01), pages 1395 - 1402, XP002976368, ISSN: 0021-9738 *
JIANG Y ET AL: "PLURIPOTENCY OF MESENCHYMAL STEM CELLS DERIVED FROM ADULT MARROW", NATURE, NATURE PUBLISHING GROUP, LONDON, GB, vol. 418, no. 6893, 4 July 2002 (2002-07-04), pages 41 - 49, XP001204372, ISSN: 0028-0836 *
ORLIC D ET AL: "Bone marrow cells regenerate infarcted myocardium", NATURE, NATURE PUBLISHING GROUP, LONDON, GB, vol. 410, 5 April 2001 (2001-04-05), pages 701 - 705, XP002965971, ISSN: 0028-0836 *
YOON YOUNG SUP ET AL: "Novel multipotent stem cells derived from human bone marrow regenerates myocardium after mocardial infarction.", CIRCULATION, vol. 108, no. 17 Supplement, 28 October 2003 (2003-10-28), & AMERICAN HEART ASSOCIATION SCIENTIFIC SESSIONS 2003; ORLANDO, FL, USA; NOVEMBER 09-12, 2003, pages IV - 158, XP002458475, ISSN: 0009-7322 *
YOON YOUNG-SUP ET AL: "Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction", JOURNAL OF CLINICAL INVESTIGATION, vol. 115, no. 2, February 2005 (2005-02-01), pages 326 - 338, XP002458476, ISSN: 0021-9738 *

Also Published As

Publication number Publication date
AU2004286322A1 (en) 2005-05-12
WO2005042723A2 (en) 2005-05-12
CN101072867A (en) 2007-11-14
CA2543794A1 (en) 2005-05-12
KR20070007030A (en) 2007-01-12
WO2005042723A3 (en) 2007-03-29
EP1685237A2 (en) 2006-08-02
WO2005042723A9 (en) 2005-08-18
JP2007519397A (en) 2007-07-19

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20060427

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL HR LT LV MK

DAX Request for extension of the european patent (deleted)
PUAK Availability of information related to the publication of the international search report

Free format text: ORIGINAL CODE: 0009015

RIN1 Information on inventor provided before grant (corrected)

Inventor name: LOSORDO, DOUGLAS, W.

Inventor name: YOON, YOUNG-SUP

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 35/12 20060101ALI20070516BHEP

Ipc: C12N 5/06 20060101AFI20070516BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20071123

17Q First examination report despatched

Effective date: 20080229

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20080911