EP1411956B8 - Use of oversulfated polysaccharides as inhibitors of hiv - Google Patents
Use of oversulfated polysaccharides as inhibitors of hiv Download PDFInfo
- Publication number
- EP1411956B8 EP1411956B8 EP02749173A EP02749173A EP1411956B8 EP 1411956 B8 EP1411956 B8 EP 1411956B8 EP 02749173 A EP02749173 A EP 02749173A EP 02749173 A EP02749173 A EP 02749173A EP 1411956 B8 EP1411956 B8 EP 1411956B8
- Authority
- EP
- European Patent Office
- Prior art keywords
- oversulfated
- hiv
- polysaccharides
- inhibitors
- ads
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000004676 glycans Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 229920001282 polysaccharide Polymers 0.000 title 1
- 239000005017 polysaccharide Substances 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000019635 sulfation Effects 0.000 abstract 1
- 238000005670 sulfation reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2001MI001633A ITMI20011633A1 (en) | 2001-07-27 | 2001-07-27 | USE OF SUPER-SULFATED BACTERIAL POLYSACCHARIDES INHIBITORS OF HIV |
ITMI20011633 | 2001-07-27 | ||
PCT/IB2002/002909 WO2003011307A1 (en) | 2001-07-27 | 2002-07-26 | Use of oversulfated polysaccharides as inhibitors of hiv |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1411956A1 EP1411956A1 (en) | 2004-04-28 |
EP1411956B1 EP1411956B1 (en) | 2005-07-06 |
EP1411956B8 true EP1411956B8 (en) | 2005-10-05 |
Family
ID=11448171
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02749173A Expired - Lifetime EP1411956B8 (en) | 2001-07-27 | 2002-07-26 | Use of oversulfated polysaccharides as inhibitors of hiv |
Country Status (11)
Country | Link |
---|---|
US (1) | US7268122B2 (en) |
EP (1) | EP1411956B8 (en) |
JP (1) | JP2005519860A (en) |
AT (1) | ATE299027T1 (en) |
CA (1) | CA2454945A1 (en) |
DE (1) | DE60204967T2 (en) |
DK (1) | DK1411956T3 (en) |
ES (1) | ES2246406T3 (en) |
IT (1) | ITMI20011633A1 (en) |
PT (1) | PT1411956E (en) |
WO (1) | WO2003011307A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20032498A1 (en) | 2003-12-17 | 2005-06-18 | Pasqua Anna Oreste | ANTITROMBOTIC POLYSACCHARIDES AT LOW MOLECULAR WEIGHT E |
ITMI20010397A1 (en) * | 2001-02-27 | 2002-08-27 | Giorgio Zoppetti | HIGHLY N, O-SULPHATED DERIVATIVES OF POLYSACCHARIDE K5 AND THEIR PREPARATION |
US8513407B2 (en) * | 2002-06-18 | 2013-08-20 | Glycores 2000 S.R.L. | Process for the preparation of N-acyl-(epi)K5-amine-O-sulfate-derivatives and products thus obtained |
WO2003106505A1 (en) * | 2002-06-18 | 2003-12-24 | Pasqua Anna Oreste | Process for the manufacture of n-acyl-(epi)k5-amine-o-sulfate-derivatives and products thus obtained |
ITMI20031618A1 (en) * | 2003-08-06 | 2005-02-07 | Inalco Spa | POLYSACCHARIDE DERIVATIVES EQUIPPED WITH HIGH ACTIVITY |
DE102006052504A1 (en) * | 2006-11-06 | 2008-05-08 | Temper, Rupert | Method for producing an agent against an infectious disease |
US9457199B2 (en) | 2014-08-08 | 2016-10-04 | Colgate-Palmolive Company | Light emitting toothbrush |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0293826A3 (en) | 1987-06-02 | 1989-05-10 | Stichting REGA V.Z.W. | Therapeutic and prophylactic application of sulfated polysaccharides against aids |
CA2007258A1 (en) * | 1989-01-11 | 1990-07-11 | Richard L. Jackson | Heparin fraction with anti-hiv activity |
FR2684385B1 (en) * | 1991-11-28 | 1997-08-01 | Sanofi Elf | HEPAROSANES-N, HIGH MOLECULAR MASS O-SULPHATES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
ITPD940054A1 (en) | 1994-03-23 | 1995-09-23 | Fidia Advanced Biopolymers Srl | SULPHATED POLYSACCHARIDES |
IT1289613B1 (en) | 1997-02-07 | 1998-10-15 | Inalco Spa | O-SULPHATED BACTERIAL POLYSACCHARIDES |
IT1290814B1 (en) * | 1997-03-24 | 1998-12-11 | Istituto Scient Di Chimica E B | GLYCOSAMINOGLICANS WITH HIGH ANTI-THROMBOTIC ACTIVITY |
ITMI20010397A1 (en) * | 2001-02-27 | 2002-08-27 | Giorgio Zoppetti | HIGHLY N, O-SULPHATED DERIVATIVES OF POLYSACCHARIDE K5 AND THEIR PREPARATION |
ITMI20010779A1 (en) * | 2001-04-12 | 2002-10-12 | Giorgio Zoppetti | USE OF BACTERIAL SULPHATE POLYSACCHARIDES SUITABLE FOR THE INHIBITION OF ANGIOGENESIS |
-
2001
- 2001-07-27 IT IT2001MI001633A patent/ITMI20011633A1/en unknown
-
2002
- 2002-07-26 JP JP2003516537A patent/JP2005519860A/en active Pending
- 2002-07-26 WO PCT/IB2002/002909 patent/WO2003011307A1/en active IP Right Grant
- 2002-07-26 CA CA002454945A patent/CA2454945A1/en not_active Abandoned
- 2002-07-26 EP EP02749173A patent/EP1411956B8/en not_active Expired - Lifetime
- 2002-07-26 ES ES02749173T patent/ES2246406T3/en not_active Expired - Lifetime
- 2002-07-26 AT AT02749173T patent/ATE299027T1/en not_active IP Right Cessation
- 2002-07-26 PT PT02749173T patent/PT1411956E/en unknown
- 2002-07-26 DE DE60204967T patent/DE60204967T2/en not_active Expired - Fee Related
- 2002-07-26 DK DK02749173T patent/DK1411956T3/en active
- 2002-07-26 US US10/484,883 patent/US7268122B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2003011307A1 (en) | 2003-02-13 |
ITMI20011633A1 (en) | 2003-01-27 |
EP1411956A1 (en) | 2004-04-28 |
JP2005519860A (en) | 2005-07-07 |
CA2454945A1 (en) | 2003-02-13 |
DK1411956T3 (en) | 2005-10-24 |
PT1411956E (en) | 2005-10-31 |
ATE299027T1 (en) | 2005-07-15 |
ITMI20011633A0 (en) | 2001-07-27 |
DE60204967D1 (en) | 2005-08-11 |
ES2246406T3 (en) | 2006-02-16 |
US7268122B2 (en) | 2007-09-11 |
DE60204967T2 (en) | 2006-05-18 |
EP1411956B1 (en) | 2005-07-06 |
US20050009780A1 (en) | 2005-01-13 |
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