EP1455816A4 - Peptides de liaison hla de classe i et ii et leurs utilisations - Google Patents
Peptides de liaison hla de classe i et ii et leurs utilisationsInfo
- Publication number
- EP1455816A4 EP1455816A4 EP01274676A EP01274676A EP1455816A4 EP 1455816 A4 EP1455816 A4 EP 1455816A4 EP 01274676 A EP01274676 A EP 01274676A EP 01274676 A EP01274676 A EP 01274676A EP 1455816 A4 EP1455816 A4 EP 1455816A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- hla class
- binding peptides
- peptides
- immunogenic
- allele
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108700028369 Alleles Proteins 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 2
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 230000006044 T cell activation Effects 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/605—MHC molecules or ligands thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07023116A EP1911461B1 (fr) | 2000-10-19 | 2001-10-18 | Peptides de liaisons HLA de classe I et II et leurs utilisations |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24235000P | 2000-10-19 | 2000-10-19 | |
US242350P | 2000-10-19 | ||
US28562401P | 2001-04-20 | 2001-04-20 | |
US285624P | 2001-04-20 | ||
PCT/US2001/051650 WO2003040165A2 (fr) | 2000-10-19 | 2001-10-18 | Peptides de liaison hla de classe i et ii et leurs utilisations |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07023116A Division EP1911461B1 (fr) | 2000-10-19 | 2001-10-18 | Peptides de liaisons HLA de classe I et II et leurs utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1455816A2 EP1455816A2 (fr) | 2004-09-15 |
EP1455816A4 true EP1455816A4 (fr) | 2007-03-28 |
Family
ID=26935024
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01274676A Withdrawn EP1455816A4 (fr) | 2000-10-19 | 2001-10-18 | Peptides de liaison hla de classe i et ii et leurs utilisations |
EP07023116A Expired - Lifetime EP1911461B1 (fr) | 2000-10-19 | 2001-10-18 | Peptides de liaisons HLA de classe I et II et leurs utilisations |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07023116A Expired - Lifetime EP1911461B1 (fr) | 2000-10-19 | 2001-10-18 | Peptides de liaisons HLA de classe I et II et leurs utilisations |
Country Status (5)
Country | Link |
---|---|
EP (2) | EP1455816A4 (fr) |
AT (1) | ATE536187T1 (fr) |
AU (1) | AU2001298049A1 (fr) |
CA (1) | CA2425648A1 (fr) |
WO (1) | WO2003040165A2 (fr) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002227406A1 (en) * | 2000-12-13 | 2002-06-24 | Argonex Pharmaceuticals | Mhc class i associated peptides for prevention and treatment of tuberculosis |
WO2003008537A2 (fr) * | 2001-04-06 | 2003-01-30 | Mannkind Corporation | Sequences d'epitope |
US20060222656A1 (en) | 2005-04-01 | 2006-10-05 | University Of Maryland, Baltimore | MAGE-A3/HPV 16 peptide vaccines for head and neck cancer |
US7049413B2 (en) * | 2001-05-18 | 2006-05-23 | Ludwig Institute For Cancer Research | MAGE-A3 peptides presented by HLA class II molecules |
WO2002094994A2 (fr) | 2001-05-18 | 2002-11-28 | Mayo Foundation For Medical Education And Research | Polypeptides chimeres specifiques d'antigene activant des lymphocytes t |
ES2606537T3 (es) | 2001-10-23 | 2017-03-24 | Psma Development Company L.L.C. | Anticuerpos contra PSMA |
US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
EP1670509A4 (fr) * | 2003-09-03 | 2007-10-31 | Dendritherapeutics Inc | Vaccins multiplex |
IL157772A (en) * | 2003-09-04 | 2016-06-30 | Bmr Solutions Ltd | Compounds containing oligopeptide derived from turtle larvae and their use to encourage mammalian hemophysis |
WO2005037855A2 (fr) * | 2003-10-17 | 2005-04-28 | Pecos Labs, Inc. | Epitopes de lymphocytes t convenant pour un vaccin contre la peste et comme outils de diagnostic, et procede d'identification correspondant |
CA2552508A1 (fr) * | 2003-12-31 | 2005-09-29 | Pharmexa Inc. | Induction de reponses immunitaires cellulaires au papillomavirus humain utilisant des compositions peptidiques et d'acides nucleiques |
GB0406054D0 (en) * | 2004-03-17 | 2004-04-21 | Univ Nottingham Trent | Prostatic acid phosphatase antigens |
GB0408164D0 (en) | 2004-04-13 | 2004-05-19 | Immune Targeting Systems Ltd | Antigen delivery vectors and constructs |
GB0716992D0 (en) | 2007-08-31 | 2007-10-10 | Immune Targeting Systems Its L | Influenza antigen delivery vectors and constructs |
WO2005105993A1 (fr) * | 2004-04-30 | 2005-11-10 | Nec Corporation | Peptide de liaison hla, précurseur, fragment d’adn de codage identique et vecteur recombinant |
JP4731867B2 (ja) | 2004-10-01 | 2011-07-27 | 国立大学法人三重大学 | Cd8陽性の細胞傷害性tリンパ球の誘導方法 |
DE102004049223A1 (de) | 2004-10-08 | 2006-04-20 | Johannes-Gutenberg-Universität Mainz | Zubereitung zum Impfen, Impfverfahren und Verwendung einer Impf-Zubereitung |
EP1709971A1 (fr) * | 2005-04-06 | 2006-10-11 | Ganymed Pharmaceuticals AG | Antigènes peptidiques utiles pour la prophylaxie, le traitement et le diagnostic des infections de poxvirus |
CA2612494A1 (fr) * | 2005-06-17 | 2006-12-28 | Mannkind Corporation | Analogues d'epitopes |
BRPI0504117A (pt) | 2005-09-05 | 2007-05-22 | Fundacao De Amparo A Pesquisa | epìtopos, combinação de epìtopos, usos de epìtopos ou sua combinação, composição, usos da composição, vacinas profiláticas anti-hiv-1, vacinas terapêuticas, método para a identificação de epìtopos e métodos para o tratamento ou prevenção |
ATE461216T1 (de) * | 2006-01-25 | 2010-04-15 | Viro Pharmaceuticals Gmbh & Co | Humaner verstärker der viralen infektion (sevi) und seine anwendung |
WO2007097561A1 (fr) | 2006-02-20 | 2007-08-30 | Ewha University - Industry Collaboration Foundation | Peptide présentant une activité de pénétration de membrane cellulaire |
EP1840133A1 (fr) * | 2006-03-29 | 2007-10-03 | Global Biotech Development Corp. Ltd. | Nouveaux peptides immunomodulants |
US20080107668A1 (en) * | 2006-08-30 | 2008-05-08 | Immunotope, Inc. | Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer |
EP2091965B9 (fr) * | 2006-10-17 | 2013-09-25 | Oncotherapy Science, Inc. | Vaccins peptidiques pour des cancers exprimant les polypeptides mphosph1 ou depdc1 |
US20090117140A1 (en) * | 2007-09-26 | 2009-05-07 | Mayumi Nakagawa | Human papilloma virus dominant CD4 T cell epitopes and uses thereof |
WO2009067584A1 (fr) * | 2007-11-20 | 2009-05-28 | Duke University | Procédés et compositions permettant de moduler l'architecture, la pharmacocinétique et la biodistribution d'un médicament-polymère |
EP2227486B1 (fr) * | 2007-11-20 | 2017-03-08 | Vianex S.A. | Analogues peptidiques et leurs conjugués |
AU2008338063B2 (en) * | 2007-12-19 | 2013-03-14 | Rhovac Aps | RhoC-based immunotherapy |
US20100166782A1 (en) * | 2008-07-25 | 2010-07-01 | Martha Karen Newell | Clip inhibitors and methods of modulating immune function |
US8975086B2 (en) | 2008-08-28 | 2015-03-10 | Oncotherapy Science, Inc. | Method for treating or preventing bladder cancer using the DEPDC1 polypeptide |
EP2334318B1 (fr) | 2008-10-06 | 2016-02-10 | Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. | Peptides stimulateurs derives de l'integrase de vih-1 interferant avec la liaison entre l'integrase et la proteine rev |
EP2391635B1 (fr) | 2009-01-28 | 2017-04-26 | Epimmune Inc. | Polypeptides de liaison de pan-dr et leurs utilisations |
JP5317336B2 (ja) * | 2009-02-23 | 2013-10-16 | 国立大学法人東北大学 | 質量分析装置を用いたタンパク質定量のための評価用ペプチド、人工標準タンパク質、及びタンパク質の定量方法 |
BRPI0924827A2 (pt) * | 2009-04-02 | 2019-01-08 | Vaxon Biotech | identificação, otimização e uso de epítopos hla-a24 crípticos para imunoterapia |
US8431530B2 (en) * | 2009-06-12 | 2013-04-30 | Morehouse School Of Medicine | Compositions and methods for treating aids or cancer by inhibiting the secretion of microparticles |
US9023802B2 (en) * | 2009-12-14 | 2015-05-05 | Immatics Biotechnologies Gmbh | HLA-binding peptides derived from prostate-associated antigenic molecules and methods of use thereof |
JP5564730B2 (ja) | 2011-08-12 | 2014-08-06 | オンコセラピー・サイエンス株式会社 | Mphosph1ペプチドおよびそれを含むワクチン |
GB201300683D0 (en) * | 2013-01-15 | 2013-02-27 | Apitope Int Nv | Peptide |
US10364451B2 (en) | 2013-05-30 | 2019-07-30 | Duke University | Polymer conjugates having reduced antigenicity and methods of using the same |
US10392611B2 (en) | 2013-05-30 | 2019-08-27 | Duke University | Polymer conjugates having reduced antigenicity and methods of using the same |
US10272144B2 (en) | 2013-07-31 | 2019-04-30 | Bioventures, Llc | Compositions for and methods of treating and preventing targeting tumor associated carbohydrate antigens |
DK3140317T3 (da) | 2014-05-09 | 2020-07-20 | Univ Southampton | Peptid-induceret nk-celleaktivering |
WO2016154530A1 (fr) | 2015-03-26 | 2016-09-29 | Duke University | Agents thérapeutiques ciblés comprenant des fusions protéine-biopolymère multivalentes |
IL254129B2 (en) | 2015-03-27 | 2023-10-01 | Immatics Biotechnologies Gmbh | New peptides and a combination of peptides for use in immunotherapy against various tumors |
GB201505305D0 (en) | 2015-03-27 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel Peptides and combination of peptides for use in immunotherapy against various tumors |
US11155585B2 (en) * | 2015-07-09 | 2021-10-26 | Intervacc Ab | Vaccine against S. suis infection |
US11458205B2 (en) | 2015-08-04 | 2022-10-04 | Duke University | Genetically encoded intrinsically disordered stealth polymers for delivery and methods of using same |
GB201513921D0 (en) * | 2015-08-05 | 2015-09-23 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers |
WO2017026503A1 (fr) | 2015-08-12 | 2017-02-16 | オンコセラピー・サイエンス株式会社 | Peptide dérivé du depdc1 et vaccin le contenant |
CN108699111B (zh) | 2015-10-08 | 2022-11-01 | 肿瘤疗法科学股份有限公司 | Mphosph1衍生的肽和包含它们的疫苗 |
GB201520570D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
US11752213B2 (en) | 2015-12-21 | 2023-09-12 | Duke University | Surfaces having reduced non-specific binding and antigenicity |
WO2017210476A1 (fr) | 2016-06-01 | 2017-12-07 | Duke University | Biocapteurs ne s'encrassant pas |
WO2018053201A1 (fr) | 2016-09-14 | 2018-03-22 | Duke University | Nanoparticules à base de polypeptide tribloc pour l'administration de médicaments hydrophiles |
KR20190064600A (ko) | 2016-09-23 | 2019-06-10 | 듀크 유니버시티 | Lcst 거동을 갖는 비구조화된 비-반복적 폴리펩티드 |
CA3042703A1 (fr) * | 2016-11-07 | 2018-05-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Developpement d'epitopes agonistes du papillomavirus humain |
WO2018132732A1 (fr) | 2017-01-12 | 2018-07-19 | Duke University | Biomatériaux hybrides lipide-polypeptide génétiquement codés qui offrent un auto-assemblage hiérarchique déclenché par la température |
WO2018187356A2 (fr) * | 2017-04-03 | 2018-10-11 | Neon Therapeutics, Inc. | Antigènes protéiques et leurs utilisations |
US11554097B2 (en) | 2017-05-15 | 2023-01-17 | Duke University | Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents |
US11680083B2 (en) | 2017-06-30 | 2023-06-20 | Duke University | Order and disorder as a design principle for stimuli-responsive biopolymer networks |
TW202019955A (zh) | 2018-07-31 | 2020-06-01 | 德商英麥提克生物技術股份有限公司 | B*07 限制肽和肽組合的抗癌免疫治療和相關方法 |
WO2020028806A1 (fr) | 2018-08-02 | 2020-02-06 | Duke University | Protéines de fusion à double agoniste |
US11512314B2 (en) | 2019-07-12 | 2022-11-29 | Duke University | Amphiphilic polynucleotides |
AU2020315981A1 (en) * | 2019-07-24 | 2022-02-17 | Agenus Inc. | Antigenic polypeptides and methods of use thereof |
NL2030990B1 (en) * | 2022-02-17 | 2023-09-01 | Academisch Ziekenhuis Leiden | T cell receptors directed against jchain and uses thereof |
CN117285597B (zh) * | 2023-11-27 | 2024-01-26 | 中国科学院烟台海岸带研究所 | 一种具有降尿酸功能的五肽kk5及其应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999027954A2 (fr) * | 1997-12-03 | 1999-06-10 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Micelles mixtes de lipopeptides pour l'induction d'une reponse immunitaire |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
US4690915A (en) | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
US4844893A (en) | 1986-10-07 | 1989-07-04 | Scripps Clinic And Research Foundation | EX vivo effector cell activation for target cell killing |
US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
ATE342730T1 (de) | 1992-08-07 | 2006-11-15 | Pharmexa Inc | Hla bindepeptide und ihre verwendungen |
BR9406652A (pt) | 1993-03-05 | 1996-09-10 | Cytel Corp | Composição |
US5804566A (en) | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
US5679647A (en) | 1993-08-26 | 1997-10-21 | The Regents Of The University Of California | Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides |
AU698962B2 (en) | 1993-09-14 | 1998-11-12 | Epimmune, Inc. | Alteration of immune response using pan DR-binding peptides |
US5739118A (en) | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
US5736524A (en) | 1994-11-14 | 1998-04-07 | Merck & Co.,. Inc. | Polynucleotide tuberculosis vaccine |
US5922687A (en) | 1995-05-04 | 1999-07-13 | Board Of Trustees Of The Leland Stanford Junior University | Intracellular delivery of nucleic acids using pressure |
US6019974A (en) | 1996-01-26 | 2000-02-01 | Emory University | SPE-4 peptides |
CA2262006A1 (fr) | 1996-07-26 | 1998-02-05 | Sloan-Kettering Institute For Cancer Research | Procedes et reactifs destines a l'immunisation genetique |
US6128946A (en) | 1997-06-26 | 2000-10-10 | Crane Nuclear, Inc. | Method and apparatus for on-line detection of leaky emergency shut down or other valves |
AU6226100A (en) | 1999-07-19 | 2001-04-24 | Epimmune, Inc. | Inducing cellular immune responses to hepatitis c virus using peptide and nucleic acid compositions |
US7026443B1 (en) | 1999-12-10 | 2006-04-11 | Epimmune Inc. | Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions |
-
2001
- 2001-10-18 EP EP01274676A patent/EP1455816A4/fr not_active Withdrawn
- 2001-10-18 EP EP07023116A patent/EP1911461B1/fr not_active Expired - Lifetime
- 2001-10-18 CA CA002425648A patent/CA2425648A1/fr not_active Abandoned
- 2001-10-18 WO PCT/US2001/051650 patent/WO2003040165A2/fr active Search and Examination
- 2001-10-18 AT AT07023116T patent/ATE536187T1/de active
- 2001-10-18 AU AU2001298049A patent/AU2001298049A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999027954A2 (fr) * | 1997-12-03 | 1999-06-10 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Micelles mixtes de lipopeptides pour l'induction d'une reponse immunitaire |
Non-Patent Citations (1)
Title |
---|
HADIDA F ET AL: "CARBOXYL-TERMINAL AND CENTRAL REGIONS OF HUMAN IMMUNODEFICIENCY VIRUS-1 NEF RECOGNIZED BY CYTOTOXIC T LYMPHOCYTES FROM LYMPHOID ORGANS AN IN-VITRO LIMITING DILUTION ANALYSIS", JOURNAL OF CLINICAL INVESTIGATION, vol. 89, no. 1, 1992, pages 53 - 60, XP002406423, ISSN: 0021-9738 * |
Also Published As
Publication number | Publication date |
---|---|
WO2003040165A3 (fr) | 2004-06-24 |
CA2425648A1 (fr) | 2002-04-19 |
AU2001298049A8 (en) | 2005-11-03 |
ATE536187T1 (de) | 2011-12-15 |
EP1911461B1 (fr) | 2011-12-07 |
WO2003040165A2 (fr) | 2003-05-15 |
EP1455816A2 (fr) | 2004-09-15 |
EP1911461A2 (fr) | 2008-04-16 |
EP1911461A3 (fr) | 2008-07-16 |
AU2001298049A1 (en) | 2003-05-19 |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20070226 |
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17Q | First examination report despatched |
Effective date: 20070529 |
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RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: PHARMEXA INC. |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20071211 |