EP1339426A4 - Anticorps a liaison immunospecifique avec les recepteurs "trail" - Google Patents

Anticorps a liaison immunospecifique avec les recepteurs "trail"

Info

Publication number: EP1339426A4
Authority: EP; European Patent Office
Prior art keywords: antibodies; immunospecifically bind; trail receptors; trail; receptors
Prior art date: 2000-11-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP01273517A

Other languages

German (de)

English (en)

Other versions

EP1339426A2 (fr

Inventor

Theodora Salcedo

Victor Roschke

Steven M Ruben

Craig A Rosen

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Human Genome Sciences Inc

Original Assignee

Human Genome Sciences Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-08

Filing date

2001-11-07

Publication date

2004-06-30

2001-11-07 Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc

2003-09-03 Publication of EP1339426A2 publication Critical patent/EP1339426A2/fr

2004-06-30 Publication of EP1339426A4 publication Critical patent/EP1339426A4/fr

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP01273517A 2000-11-08 2001-11-07 Anticorps a liaison immunospecifique avec les recepteurs "trail" Withdrawn EP1339426A4 (fr)

Applications Claiming Priority (11)

Application Number	Priority Date	Filing Date	Title
US24661200P	2000-11-08	2000-11-08
US246612P		2000-11-08
US24884700P	2000-11-16	2000-11-16
US248847P		2000-11-16
US25290400P	2000-11-27	2000-11-27
US252904P		2000-11-27
US29501801P	2001-06-04	2001-06-04
US295018P		2001-06-04
US32735901P	2001-10-09	2001-10-09
US327359P		2001-10-09
PCT/US2001/042996 WO2002079377A2 (fr)	2000-11-08	2001-11-07	Anticorps a liaison immunospecifique avec les recepteurs 'trail'

Publications (2)

Publication Number	Publication Date
EP1339426A2 EP1339426A2 (fr)	2003-09-03
EP1339426A4 true EP1339426A4 (fr)	2004-06-30

Family

ID=27540243

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP01273517A Withdrawn EP1339426A4 (fr)	2000-11-08	2001-11-07	Anticorps a liaison immunospecifique avec les recepteurs "trail"

Country Status (4)

Country	Link
EP (1)	EP1339426A4 (fr)
AU (1)	AU2001297702A1 (fr)
CA (1)	CA2426710A1 (fr)
WO (1)	WO2002079377A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7476383B2 (en)	2000-05-02	2009-01-13	The Uab Research Foundation	Antibody selective for DR4 and uses thereof
US7279160B2 (en)	2000-05-02	2007-10-09	The Uab Research Foundation	Combinations of DR5 antibodies and other therapeutic agents
TWI318983B (en)	2000-05-02	2010-01-01	Uab Research Foundation	An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof
US7115717B2 (en)	2001-05-18	2006-10-03	Kirin Beer Kabushiki Kaisha	Anti-TRAIL-R antibodies
EP1531162A1 (fr) *	2003-11-14	2005-05-18	Heinz Vollmers	Anticorps SAM-6, spécifique d'adénocarcinome, et ses utilisations
WO2006083937A2 (fr)	2005-02-02	2006-08-10	The Uab Research Foundation	Agents et methodes associes a la reduction de la resistance aux agonistes des recepteurs de mort induisant l'apoptose
WO2008094319A2 (fr)	2007-02-01	2008-08-07	The Board Of Regents Of The University Of Texas Sytem	Procédés et compositions d'agonistes/activateurs du récepteur de mort trail
US10150800B2 (en)	2013-03-15	2018-12-11	Zyngenia, Inc.	EGFR-binding modular recognition domains

Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998032856A1 (fr) *	1997-01-28	1998-07-30	Human Genome Sciences, Inc.	Recepteur 4 (dr4-recepteur 4 de mort cellulaire) contenant des domaines de mort cellulaire, membre de la superfamille du recepteur du facteur de necrose tumorale (tnf) et se liant a la queue (apo2-l)
WO1999037684A1 (fr) *	1998-01-26	1999-07-29	Genentech, Inc.	Anticorps du recepteur 4 de la mort cellulaire (dr4) et leurs utilisations
WO1999064461A2 (fr) *	1998-06-12	1999-12-16	Genentech, Inc.	Procede pour fabriquer des anticorps monoclonaux et anticorps a reaction croisee obtenus par ce procede
WO2002002641A1 (fr) *	2000-06-16	2002-01-10	Human Genome Sciences, Inc.	Anticorps se liant de maniere immunospecifique a un stimulateur de lymphocyte b
WO2002016436A2 (fr) *	2000-08-22	2002-02-28	Novartis Ag	ANTICORPS DE LA IL-1β HUMAINE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0835305B1 (fr) *	1995-06-29	2005-11-23	Immunex Corporation	Cytokine inductrice d'apoptose
US6072047A (en) *	1997-02-13	2000-06-06	Immunex Corporation	Receptor that binds trail
AU9386398A (en) *	1997-09-12	1999-03-29	Biogen, Inc.	Cysteine rich receptors: trail

2001
- 2001-11-07 EP EP01273517A patent/EP1339426A4/fr not_active Withdrawn
- 2001-11-07 WO PCT/US2001/042996 patent/WO2002079377A2/fr not_active Application Discontinuation
- 2001-11-07 CA CA002426710A patent/CA2426710A1/fr not_active Abandoned
- 2001-11-07 AU AU2001297702A patent/AU2001297702A1/en not_active Abandoned

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998032856A1 (fr) *	1997-01-28	1998-07-30	Human Genome Sciences, Inc.	Recepteur 4 (dr4-recepteur 4 de mort cellulaire) contenant des domaines de mort cellulaire, membre de la superfamille du recepteur du facteur de necrose tumorale (tnf) et se liant a la queue (apo2-l)
WO1999037684A1 (fr) *	1998-01-26	1999-07-29	Genentech, Inc.	Anticorps du recepteur 4 de la mort cellulaire (dr4) et leurs utilisations
WO1999064461A2 (fr) *	1998-06-12	1999-12-16	Genentech, Inc.	Procede pour fabriquer des anticorps monoclonaux et anticorps a reaction croisee obtenus par ce procede
WO2002002641A1 (fr) *	2000-06-16	2002-01-10	Human Genome Sciences, Inc.	Anticorps se liant de maniere immunospecifique a un stimulateur de lymphocyte b
WO2002016436A2 (fr) *	2000-08-22	2002-02-28	Novartis Ag	ANTICORPS DE LA IL-1β HUMAINE

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 2 August 2000 (2000-08-02), XP002277545, retrieved from EBI Database accession no. AAY82615 *
DATABASE EMBL [online] 28 August 2001 (2001-08-28), XP002277565, retrieved from EBI Database accession no. AAB99378 *
DATABASE EMBL [online] 3 October 2000 (2000-10-03), XP002277544, retrieved from EBI Database accession no. AAY93734 *
DATABASE UNIPROT [online] 1 May 2000 (2000-05-01), XP002277546, retrieved from EBI Database accession no. Q9UL86 *
GRIFFITH T S ET AL: "FUNCTIONAL ANALYSIS OF TRAIL RECEPTORS USING MONOCLONAL ANTIBODIES", JOURNAL OF IMMUNOLOGY, THE WILLIAMS AND WILKINS CO. BALTIMORE, US, vol. 162, no. 5, 1 March 1999 (1999-03-01), pages 2597 - 2605, XP000918935, ISSN: 0022-1767 *
See also references of WO02079377A3 *

Also Published As

Publication number	Publication date
EP1339426A2 (fr)	2003-09-03
CA2426710A1 (fr)	2002-10-10
WO2002079377A2 (fr)	2002-10-10
WO2002079377A3 (fr)	2003-03-13
AU2001297702A1 (en)	2002-10-15

Publication	Publication Date	Title
EP1465925A4 (fr)	2006-02-08	Anticorps se liant de maniere immunospecifique a des recepteurs trail
HK1075470A1 (en)	2005-12-16	Antibodies that immunospecifically bind to trail receptors
EP1572874A3 (fr)	2005-10-20	Anticorps se liant de maniere immunospecifique a des recepteurs de trail
CY2012003I2 (el)	2020-05-29	Αντισωματα που συνδεονται ανοσοειδικως προς blys
AU2002364954A8 (en)	2003-07-15	Antibodies that immunospecifically bind to blys
AU4835001A (en)	2001-09-24	Antibodies to human cd154
HK1203521A1 (en)	2015-10-30	Antibodies to nsulin-like growth factor receptor
IL213564A0 (en)	2011-07-31	Antibodies to vla-1
HK1061403A1 (en)	2004-09-17	ANTIBODIES TO HUMAN IL-1ß
EP1411983A4 (fr)	2006-06-21	Anticorps bispecifiques se liant aux recepteurs vegf
HUP0301477A3 (en)	2005-11-28	Antibodies to human mcp-1 molecule
AU2003234706A8 (en)	2003-11-03	Antibodies that specifically bind to tl5
AU2003218456A8 (en)	2003-10-20	Antibodies that specifically bind to gmad
EP1633316A4 (fr)	2008-04-02	Anticorps se liant de maniere immunospecifique aux recepteurs trail
AU2003240822A8 (en)	2003-12-19	Antibodies that specifically bind to neurokinin b
EP1339426A4 (fr)	2004-06-30	Anticorps a liaison immunospecifique avec les recepteurs "trail"
AU2003259835A8 (en)	2004-03-03	Antibodies that immunospecifically bind to trail receptors
AU2002352676A1 (en)	2003-05-26	Antibodies that immunospecifically bind to trail receptors
AU2003228483A8 (en)	2003-10-27	Antibodies that specifically bind to tr2
IL126245A0 (en)	1999-05-09	Antibodies to ifn-beta2/il-6 receptor
TH0101005173A (th)	2016-06-21	แอนติบอดี้ต่อโกรทแฟคเตอร์ i รีเซฟเตอร์ที่เหมือนอินซูลิน
DK2275449T3 (da)	2017-01-02	Antistoffer, der immunspecifikt binder til BLyS
GB0020794D0 (en)	2000-10-11	Humanised antibodies
AU2002345927A1 (en)	2003-03-03	Bispecific antibodies that bind to vegf receptors
GB0003359D0 (en)	2000-04-05	Monoclonal antibodies

Legal Events

Date	Code	Title	Description
2003-07-18	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2003-09-03	17P	Request for examination filed	Effective date: 20030605
2003-09-03	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
2003-09-03	AX	Request for extension of the european patent	Extension state: AL LT LV MK RO SI
2004-06-16	RIC1	Information provided on ipc code assigned before grant	Ipc: 7C 07K 16/28 B Ipc: 7A 61K 39/00 A
2004-06-30	A4	Supplementary search report drawn up and despatched	Effective date: 20040513
2005-04-27	17Q	First examination report despatched	Effective date: 20050311
2006-12-15	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2007-01-17	18D	Application deemed to be withdrawn	Effective date: 20060704