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EP1272224A4 - Genexpressionsprofile im gewebe der speiseröhre - Google Patents

Genexpressionsprofile im gewebe der speiseröhre

Info

Publication number
EP1272224A4
EP1272224A4 EP01924375A EP01924375A EP1272224A4 EP 1272224 A4 EP1272224 A4 EP 1272224A4 EP 01924375 A EP01924375 A EP 01924375A EP 01924375 A EP01924375 A EP 01924375A EP 1272224 A4 EP1272224 A4 EP 1272224A4
Authority
EP
European Patent Office
Prior art keywords
gene expression
expression profiles
esophageal tissue
esophageal
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01924375A
Other languages
English (en)
French (fr)
Other versions
EP1272224A1 (de
Inventor
Amanda Williams
Joseph F Boland
Reginald V Lord
Christopher Alvares
Jon C Wetzel
Uwe Scherf
Joseph G Vockley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ore Pharmaceuticals Inc
Original Assignee
Ore Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ore Pharmaceuticals Inc filed Critical Ore Pharmaceuticals Inc
Publication of EP1272224A1 publication Critical patent/EP1272224A1/de
Publication of EP1272224A4 publication Critical patent/EP1272224A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Evolutionary Biology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP01924375A 2000-03-31 2001-03-28 Genexpressionsprofile im gewebe der speiseröhre Withdrawn EP1272224A4 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US19344600P 2000-03-31 2000-03-31
US23773300P 2000-10-05 2000-10-05
US237733P 2000-10-05
PCT/US2001/009847 WO2001074405A1 (en) 2000-03-31 2001-03-28 Gene expression profiles in esophageal tissue
US193446P 2002-07-11

Publications (2)

Publication Number Publication Date
EP1272224A1 EP1272224A1 (de) 2003-01-08
EP1272224A4 true EP1272224A4 (de) 2004-09-29

Family

ID=26888993

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01924375A Withdrawn EP1272224A4 (de) 2000-03-31 2001-03-28 Genexpressionsprofile im gewebe der speiseröhre

Country Status (4)

Country Link
EP (1) EP1272224A4 (de)
AU (1) AU2001251034A1 (de)
CA (1) CA2405431A1 (de)
WO (1) WO2001074405A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002222939A1 (en) * 2000-07-19 2002-01-30 Takara Bio Inc. Method of detecting cancer
US7803370B2 (en) 2002-08-30 2010-09-28 Oncotherapy Science, Inc. Method for treating synovial sarcoma
WO2004020668A2 (en) * 2002-08-30 2004-03-11 Oncotherapy Science, Inc. Method for treating synovial sarcoma
US20040146907A1 (en) * 2002-11-13 2004-07-29 Genentech, Inc. Methods and compositions for detecting dysplasia
WO2005076005A2 (en) * 2004-01-30 2005-08-18 Medizinische Universität Wien A method for classifying a tumor cell sample based upon differential expression of at least two genes
US20050186577A1 (en) 2004-02-20 2005-08-25 Yixin Wang Breast cancer prognostics
EP1851340B1 (de) * 2005-02-10 2013-01-30 GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Verfahren zur diagnose und behandlung von krebs mittels b-catenin-spleissvarianten
WO2006118308A1 (ja) * 2005-05-02 2006-11-09 Toray Industries, Inc. 食道ガン及び食道ガン転移診断のための組成物及び方法
EP2311986B1 (de) * 2005-07-27 2015-04-15 Oncotherapy Science, Inc. Verfahren zur Diagnose von Ösophaguskrebs
GB0526498D0 (en) * 2005-12-28 2006-02-08 Randox Lab Ltd Method
RU2412203C2 (ru) 2006-06-21 2011-02-20 Онкотерапи Сайенс, Инк. Направленные на опухоль моноклональные антитела против fzd10 и их применение
WO2008021115A2 (en) * 2006-08-14 2008-02-21 The Brigham And Women's Hospital, Inc. Diagnostic tests using gene expression ratios
CN102089428B (zh) * 2008-05-21 2013-11-13 东丽株式会社 食道癌确定用组合物及方法
GB201005048D0 (en) 2010-03-24 2010-05-12 Medical Res Council Prognosis of oesophageal and gastro-oesophageal junctional cancer
AU2012229102B2 (en) * 2011-03-17 2016-02-04 Cernostics, Inc. Systems and compositions for diagnosing Barrett's esophagus and methods of using the same
GB201208756D0 (en) * 2012-05-17 2012-07-04 Medical Res Council Methods
ES2931924T3 (es) 2015-11-25 2023-01-04 Cernostics Inc Métodos para detectar la transformación maligna del esófago de Barrett
TWI762516B (zh) 2016-10-06 2022-05-01 日商腫瘤療法 科學股份有限公司 針對ｆｚｄ１０之單株抗體及其用途
CN109342729B (zh) * 2018-10-30 2021-06-25 深圳格道糖生物技术有限公司 特定凝集素组合在基于唾液糖型鉴别食管癌方面的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001094629A2 (en) * 2000-06-05 2001-12-13 Avalon Pharmaceuticals Cancer gene determination and therapeutic screening using signature gene sets
WO2002064171A1 (en) * 2001-02-12 2002-08-22 Thomas Jefferson University Adenoviral transduction of fragile histidine triad (fhit) into cancer cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996034112A1 (en) * 1995-04-24 1996-10-31 Chromaxome Corp. Methods for generating and screening novel metabolic pathways
EP1012240B1 (de) * 1997-01-31 2008-03-19 Edward P. Cohen Krebs immuntherapie mit semi-allogenen zellen
JP2001511550A (ja) * 1997-07-25 2001-08-14 アフィメトリックス インコーポレイテッド プローブアレイチップ設計データベースを提供するための方法よびシステム

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001094629A2 (en) * 2000-06-05 2001-12-13 Avalon Pharmaceuticals Cancer gene determination and therapeutic screening using signature gene sets
WO2002064171A1 (en) * 2001-02-12 2002-08-22 Thomas Jefferson University Adenoviral transduction of fragile histidine triad (fhit) into cancer cells

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; October 1999 (1999-10-01), ZHOU J ET AL: "[Gene expression profiles in squamous esophageal cancer tissues and adjacent almost normal tissues]", XP002273969, Database accession no. NLM10514537 *
SEBASTIAN J L ET AL: "The use of large-scale cDNA analysis to profile differential gene expression in KYSE 410 human esophageal cancer cells after irradiation.", BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE. UNITED STATES SEP 2000, vol. 130, no. 9, September 2000 (2000-09-01), pages 882 - 885, XP009027930, ISSN: 0007-4888 *
See also references of WO0174405A1 *
ZHONGHUA YI XUE YI CHUAN XUE ZA ZHI = ZHONGHUA YIXUE YICHUANXUE ZAZHI = CHINESE JOURNAL OF MEDICAL GENETICS. CHINA OCT 1999, vol. 16, no. 5, October 1999 (1999-10-01), pages 303 - 306, ISSN: 1003-9406 *

Also Published As

Publication number Publication date
WO2001074405A9 (en) 2003-06-12
EP1272224A1 (de) 2003-01-08
AU2001251034A1 (en) 2001-10-15
CA2405431A1 (en) 2001-10-11
WO2001074405B1 (en) 2001-11-29
WO2001074405A1 (en) 2001-10-11

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Legal Events

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Ipc: 7A 61K 31/7088 B

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Ipc: 7G 06F 19/00 A

A4 Supplementary search report drawn up and despatched

Effective date: 20040811

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Effective date: 20071002