EP0915737B1 - Collector device - Google Patents

Abstract

A holding device for body fluid, tissue parts and tissue culture media includes a cylindrical holding container having a container wall with an inner surface defining an inner space, a first open end face having a diameter which is at least equal to the diameter of the inner space, and a second open end face having a conical sealing surface tapering inwardly in the direction of the inner space. A first closure device closes the first open end face and a second closure device closes the second end face. The second closure device includes a solid conical seal body 44 having a sealing surface conforming to the conical sealing surface of the second open end face and an outer end face of a larger diameter than that of an inner end face that faces the inner space. A retaining member 45 abuts the outer end face and is coupled to the outer container wall surface for holding the seal body in a sealing position in the second open end face.

Description

The invention relates to a receiving device according to the preamble of claim 1.

From US 4,342,724 A is a receiving device with a receiving container as well Both open end regions arranged closable locking devices as needed known. The receptacle has a container wall with inner and outer-surface-on, which bounds an interior. The two open formed end areas can each be closed by sealing bodies of the closure devices, the wall parts interacting with the sealants each being cylindrical are trained. The sealing in the end area shown below is done by the Interaction of the sealing washer resting on the front end of the receptacle with the Holding cap that presses the sealing washer onto the front end of the receptacle. The Insert part points in the direction of the cylindrical inner surface Centering flanges spaced apart from one another along the longitudinal central axis, with displacement of the Insert part in the direction of the longitudinal axis through a cooperating with the receptacle Holding approach is prevented. In addition, the insert part in the area of Longitudinal central axis on an opening completely penetrating this, which between the two ends of the same. The further end region of the receptacle points a smaller cross-sectional dimension compared to the wider interior.

WO 93/22647 A1 describes a method and an apparatus for separating a mixture of at least two media, in which the receptacle through an approximately cylindrical or tubular housing with a container wall is formed, which delimits an interior and the receptacle two in End regions spaced apart from one another in the direction of its longitudinal central axis, each with open ones Has end faces. These two openings are by means of closable opening devices if necessary closable, one of which the receptacle on its outer Surface overlaps and the other closure device is designed such that this comprises a pierceable sealing body and a holding element for the sealing body, wherein the sealing body is inserted into the interior of the receptacle and the holding element engages over the receptacle in the area of its outer surface. Furthermore is in the interior of the receptacle a separator is used, which by a Base body is formed with sealing lips protruding therefrom.

A receptacle for centrifuging has become known from US 3,434,615 A, which is formed by a container body open on one side, which one neck-like approach, with an inner surface of the neck-like approach tapering is formed in the direction of the interior. In this conical neck area is a conical sealing device in the form of a sealing plug can be used with sealing rings arranged on the circumference, with the sealing plug on the side facing away from the interior of the housing from a flange of a cap in Reference to the housing is kept. There is also a between the cap and the housing Screw thread arranged with which the cap on the housing or its neck-shaped Approach is screwable. Due to the interaction of the sealing plug and the Cap on the one hand and between the cap and the neck-shaped extension of the housing on the other the sealing plug can be placed in a sealing system on the conical sealing surface become.

Another blood collection device has become known from US Pat. No. 3,897,343 A, the separating device already in the area before the introduction of the media to be separated the closed end of the receptacle is arranged. In the area of the open A pierceable closure device is arranged at the front end of the receptacle, which for introducing the medium into the interior of the receiving device from a Pierce the needle and then insert the medium into the interior becomes. As a result, the separation device is located below before the separation process begins of the medium to be separated and only floats after the centrifugal force has been applied of the chosen specific weight on the separated and heavier components of the medium and takes up only after the centrifugal force has been applied a sealing position between the two separate components of the medium on. A disadvantage of this method which has become known here and that which has become known The device is that the separation device with both before the start of the separation process Components of the medium come into contact and it is possible that partial quantities the heavier medium in the area above the sealing device on the separating device stick and thus subsequently mixing or contaminating the Lighter medium located above the separation device after the separation process has ended is possible.

Furthermore, a receiving device for a mixture of at least two media, according to DE 19 513 453 A1, is already known, which has a test tube-like receiving container which is closed in an open end region with a closure device and in which a separating device for separating the different media of the mixture the separation is used. In order to prevent the end face of the separating device, which subsequently only comes into contact with a medium, from becoming contaminated when the mixture is poured into the interior of the container, the separating device is provided in the central region with a through-opening through which the mixture enters the remaining interior of the receptacle can be introduced. During the subsequent separation process by centrifugation in a conventional manner with a radial centrifugal force (rcf) of 1,000 g to 5,000 g - where g is gravity and 1 g is 9.81 m / s ² - this becomes the one medium separated from the mixture transferred through the opening in the separating device into the area located between the sealing device and the separating device and consequently sinks in the direction of the closed end of the receptacle. In order to prevent the other medium located between the closed end and the separating device from mixing again with the medium separated therefrom after the break through the opening, a height corresponding to the usual remaining amount of the other medium is in the direction of the closed one End provided conically widening end stop, with which the separating device runs on the end stop, which penetrates through the opening. As soon as the outer diameter of the end stop corresponds to the inner diameter of the opening, the separating device remains in this position and the opening is closed with the stop, and the two media cannot be exchanged or mixed again. The disadvantage of this embodiment variant is that a special tube with an internal stop has to be manufactured and no reliable function of the medium separation can be ensured due to the opening arranged in the separating device.

Other receptacles for centrifuging mixtures to be separated from at least two different media, in which the receptacle in both frontal areas is closed with a closure device are known from WO 96/05770 A1. Inside is a separating device formed by a sealing washer, which is formed by a gel. During the centrifugation process, this gel flask migrates due to its specific weight, which is higher than the specific weight of the medium with the lower specific weight and lower than the specific weight the medium with a higher specific weight, due to the centrifugal forces acting on it between the two different, separate media. Positioned in this Position can thus separate one medium from the other medium Mixture take place. The disadvantage here is that the storage period, due to the separating device made of gel, in many cases not sufficient for the normal duration of use.

The present invention has for its object to provide a recording device Separation of several media to create a mixture, which quickly to different Mixtures are adaptable and a long storage period and high operational reliability too when used by inexperienced personnel.

The object of the invention is achieved by the design of the receiving device according to the Characteristic part of claim 1 solved. Due to the design of the receptacle in connection with the two closure devices in the region of the two end regions simple filling of the interior of the receptacle is made possible. This configuration enables a reinforced floor area, which also if such a receptacle is accidentally dropped, bursting prevented with high security. In addition, this receptacle is relatively simple designed injection molding tools easily and also in tools with multiple nests can be produced inexpensively. Furthermore, this reinforced area can simultaneously be used to securely anchor the holding element.

Further advantageous refinements of the receptacle, which are also fully automatic Enable assembly in an assembly device in a preferably the same assembly direction, are given in claims 3 to 8.

Safe positioning of the separator in the receptacle until the start of the Centrifugation also during the introduction and removal of media in or out of the Receptacle can be achieved by the variants according to claim 9 to 13.

The further development according to claim 14 also allows manufacturing tolerances or temperature-related ones Fluctuations in diameter can be easily compensated.

Adequate pretensioning of the sealing body in the opening can be achieved through further training can be achieved according to claims 15 and 16.

Due to the configuration according to claim 17, it is also possible to remove without loss of sealing of materials from the interior of the receptacle through the sealing body to allow through.

A good installation of the sealing body and a drip from the outlet can be achieved through further training be avoided according to claim 18.

Adequate tightness can also be achieved by developing the sealing body according to claim 19 can be achieved because it also uses materials that meet the high Centrifugal forces have sufficient dimensional stability to ensure tightness.

By the configurations according to claims 20 to 25, a secure mounting of the Sealing body achieved in the receptacle and still ensured that the receptacle with the new closure device in the existing centrifuges without any problems can be used.

The embodiment according to claim 26 allows a roll-off protection in a simple manner prevents the receptacle, if it has a cylindrical outer shape, can roll away.

Pulling out the sealing body to the interior of the receptacle through the Making opening accessible is favored by the training according to claims 27 to 29.

A sufficient prestressing force of the sealing body in the receptacle can be obtained from the claims 30 and 31 can be achieved, with the latter embodiment despite a good Support of the sealing body, the accessibility to the interior of the receptacle is ensured remains.

The receiving device can also advantageously be used in conjunction with a separating device be used according to claim 32, because by dividing them into a sealing element and a support body, the two parts are each optimally configured according to their function can be. Due to the use of its own support body is due to the density and the specific weight related to the different applications easily adjustable. In addition there is a good seal after separation between the separate media is achieved, which also requires longer storage allows. Furthermore, a full seal over the entire circumference and thus one flawless separation can be ensured even under different pressure conditions.

According to claim 33, the separating device can be selected by the choice of material for the sealing element matched to the various components of the mixture to be separated and so on the one hand a perfect separation during the centrifugation process and on the other hand after the same a secure seal between the separate components of the mixture can be achieved.

Different configurations of the receiving device, which allow universal use of the same made possible in various fields of application are in claims 34 to 37 specified.

Due to the further development according to claim 38, a sensitive coordination of the separating effect is possible between media or liquids with different specific weights or different density by the exact determination of the specific weight or Carrier body density possible.

The selection of a material is also advantageous, as is the case in claims 39 to 41 is indicated, as a permanent durability of the support body is achieved, which in wide range of different applications, especially in blood analysis Separation of the liquids due to the different specific weights or densities made possible by itself.

Further advantageous refinements of the separating device that manufacture the same as well as an exact separation of different media and a high level of tightness, are given in claims 42 to 47.

Due to the advantageous development according to claim 48, in each operating state especially during centrifugation, even when centrifugal forces act differently, that the separating device with its axis of rotation one to the longitudinal central axis of the Can take vertical position.

The training variant according to claim 49 enables production in a simple manner a passage gap for one of the two media during the centrifugation process.

Other embodiments, the universal adaptation of the separator and different Enable uses are given in claims 50 to 52.

Through the development according to claim 53, it is possible under certain circumstances, the restoring force to properly center the separator in the receptacle at the end to improve the centrifugation process, including training according to the claims 54 to 56 can be used with advantage.

Finally, the refinements according to claims 57 to 59 enable a precise position Holding the separator before using the same or until the beginning of Centrifugation process.

The invention is described below with reference to the exemplary embodiments shown in the drawings explained in more detail.

Fig. 1

eine erfindungsgemäß ausgebildete Aufnahmeeinrichtung, z.B. für Blut, in Seitenansicht, geschnitten und vereinfachter, schematischer Darstellung;

Fig. 2

die Aufnahmeeinrichtung nach Fig. 1, in einer Ansicht von unten gemäß einem Pfeil II in Fig. 1;

Fig. 3

eine weitere mögliche Ausführungsform einer Verschlußvorrichtung für die Aufnahmeeinrichtung in Seitenansicht, geschnitten und vereinfachter, schematischer Darstellung;

Fig. 4

eine mögliche Ausbildung einer Trennvorrichtung für die Aufnahmeeinrichtung in schaubildlich vereinfachter Darstellung;

Fig. 5

eine Aufnahmeeinrichtung mit einer in deren Innenraum angeordneten Trennvorrichtung während des Trennvorganges in Seitenansicht, geschnitten und vereinfachter, schematischer Darstellung;

Fig. 6

eine mögliche und gegebenenfalls für sich eigenständige Ausführungsform eines Halteelements bzw. einer Kappe in Draufsicht und vereinfachter, schematischer Darstellung;

Fig. 7

eine weitere und gegebenenfalls für sich eigenständige Ausführungsform einer Trennvorrichtung in Seitenansicht, geschnitten und vereinfachter, schematischer Darstellung;

Fig. 8

eine weitere und gegebenenfalls für sich eigenständige Ausführungsform einer Aufnahmeeinrichtung mit einer Halterungsvorrichtung für die Trennvorrichtung in Seitenansicht, geschnitten und vereinfachter, schematischer Darstellung;

Fig. 9

eine weitere und gegebenenfalls für sich eigenständige Ausführungsform einer Halterungsvorrichtung für die Trennvorrichtung innerhalb der Aufnahmeeinrichtung in Seitenansicht, geschnitten und vereinfachter, schematischer Darstellung;

Fig. 10

eine der möglichen Ausbildungsformen der Aufnahmeeinrichtung nach erfolgtem Trennvorgang des Gemisches in Seitenansicht, geschnitten und vereinfachter, schematischer Darstellung;

Fig. 11

eine weitere und gegebenenfalls für sich eigenständige Ausführungsform einer Trennvorrichtung mit unterschiedlich ausgebildeten Dichteiementen in Seitenansicht, geschnitten und vereinfachter, schematischer Darstellung.

Show it:

Fig. 1

a receiving device designed according to the invention, for example for blood, in side view, cut and simplified, schematic representation;

Fig. 2

1, in a view from below according to an arrow II in Fig. 1;

Fig. 3

another possible embodiment of a closure device for the receiving device in side view, sectioned and simplified, schematic representation;

Fig. 4

a possible design of a separating device for the receiving device in a graphically simplified representation;

Fig. 5

a receiving device with a separation device arranged in the interior thereof during the separation process in a side view, sectioned and simplified, schematic representation;

Fig. 6

a possible and possibly independent embodiment of a holding element or a cap in plan view and simplified, schematic representation;

Fig. 7

a further and possibly independent embodiment of a separation device in side view, sectioned and simplified, schematic representation;

Fig. 8

a further and possibly independent embodiment of a receiving device with a holding device for the separating device in side view, sectioned and simplified, schematic representation;

Fig. 9

a further and possibly independent embodiment of a mounting device for the separating device within the receiving device in side view, sectioned and simplified, schematic representation;

Fig. 10

one of the possible forms of training of the receiving device after the separation process of the mixture in side view, cut and simplified, schematic representation;

Fig. 11

a further and possibly independent embodiment of a separation device with differently designed sealing elements in side view, sectioned and simplified, schematic representation.

In the introduction it should be noted that in the differently described embodiments same parts with the same reference numerals or same component names provided with the disclosures contained throughout the description analogously for the same parts with the same reference numerals or the same component names be valid. The directions given in the description, e.g. above or below, only to refer to the representation chosen here and are analogous in the event of a change of location to be transferred to this new location. Furthermore, also Individual features from the different exemplary embodiments shown for themselves represent independent, inventive solutions.

1 and 2 show a receiving device 1 for a mixture 2 of at least two mutually different constituents or media 3, 4, such as body fluids, tissue parts or tissue dressings, which is designed in such a way that that in the receiving device 1 Mixture 2 is separable in at least two of its components. This separation or separation of the mixture 2 into its constituents or media 3, 4 can, for example, be carried out physically by centrifugation in a conventional manner and starting from the rest position until a radial centrifugal force (rcf) of 1,000 g to 5,000 g, preferably 2,200 g can be carried out, g being the force of gravity and 1 g being 9.81 m / s ² . This makes it possible, for example, to separate the solid phase from the liquid phase, as will be described in more detail in the following figures.

The receiving device 1 consists of an approximately cylindrical one Receptacle 5 with arranged at both end portions 6, 7 spaced from each other Closure devices 8, 9 and one into one of the receptacle 5 enclosed interior 10 used separator 11. This receptacle 5 can, for example, also be designed as an evacuated blood sampling tube or be used.

The receptacle 5 can be bottle-shaped, vial-shaped or piston-shaped, for example Like. As well as made of different materials, such as Plastic or glass. Used as a material for the receptacle Chosen plastic, this can be liquid-tight, in particular waterproof and optionally be gastight and, for example, as polypropylene (PP), polyethylene (PE), high-density polyethylene (PE-HD), acrylonitrite-butadiene-styrene copolymers (ABS) or the like. Or a combination thereof. Furthermore, the receptacle points 5 a container wall 12 with a wall thickness 13, the container wall 12, starting from one end region 6 with approximately the same internal dimension 14 extends to the further end region 7. The container wall 12 of the receptacle 5 has an inner surface 15 facing the interior 10 and an outer surface 16 facing away from it, which thus has an outer circumference 17 sets for the receptacle 5. Due to the inner surface 15 of the container wall 12 with the inner clear dimension 14 is thus an inner cross section 18, which has a wide variety of cross-sectional shapes, e.g. circular, elliptical, oval, polygonal, etc., may have set. Due to the inner Dimension 14 plus twice the wall thickness 13 of the receptacle 5 forms an outer dimension 19 with an outer cross section 20. The The shape of the outer cross section 20 can in turn be circular, elliptical, oval, be polygonal, etc., but it is also possible to shape the outer Cross-section 20 to be different from the shape of the inner cross-section 18.

It is also possible that the inner dimension 14 and the outer dimension 19 of the receptacle 5, starting from an end region 6 to that of this distanced further end region 7 preferably decreases minimally in terms of shape is formed, for example, the receptacle 5 when it is off Plastic material is manufactured in an injection molding process from the injection mold easy to demould. Centric to the inner dimension 14 or the inner cross section 18, the receptacle 5 points out from the end region 6 to the end region 7 extending longitudinal central axis 21.

As can also be seen from this illustration, the end region 6 has an open one Front side 22, which can be closed by the closure device 8, which can be opened as required is. For this purpose, the closure device 8 consists of an open end face 22 comprehensive cap 23 and a sealing device 24 held therein, such for example a sealing plug 25 made of a pierceable, highly elastic and self-sealing material, such as Pharmaceutical rubber, silicone rubber or Bromobutyl. This cap 23 is arranged concentrically with the longitudinal central axis 21 and formed by an annular cap jacket 26. Between the cap 23 and the sealing device 24 there are coupling means, such as coupling parts 27 to 30 of a coupling device 31 in the case of the cap 23, at least partially arranged over the inner circumference Extensions 32, 33, possibly a retaining ring 34, and in the sealing device 24 from a protruding at least in regions over its outer circumference Approach 35 provided. The sealing device 24 is in the present exemplary embodiment formed by the sealing plug 25 and has a circumferential and in cylindrical sealing surface arranged approximately concentrically to the longitudinal center axis 21 36, which in its sealing position in the section of the end region 6 on the inner Surface 15 of the receptacle 5 comes to rest. This is in this Section of the inner surface 15 of the receptacle 5 in its surface quality to form as a sealing surface. Furthermore, the sealing device 24 has an approximately aligned on the longitudinal center axis 21, further sealing surface 37, which in cooperation with the sealing surface 36 abutting the inner surface 15 the interior 10 of the receptacle 5 on its open end face 22 opposite seals off or seals off the external environment. By arranging the extension 33 between the projection 35 projecting beyond the sealing surface 36 and the end face 22 of the The receptacle 5 can adhere or strongly adhere the attachment 35 be avoided directly on the end face 22.

Furthermore, the sealing device 24 can preferably be on the retaining ring 34 facing side have a recess 38 which has approximately the same cross-sectional area has an opening 39, this opening 39 being of such dimensions is formed that an unhindered passage and subsequent piercing through the sealing device 24 is possible.

The approach 35 forming the coupling part 29, which over the sealing surface 36 Sealing device 24 projects at least in parts of the circumference like a flange, is held between the extensions 32 and 33, which in two towards the Longitudinal center axis 21 spaced apart and arranged perpendicular to this Arranged level and, for example, as at least in some areas or also annular circumferential projections or locking projections are formed. For safe Holding the sealing device 24 in the cap 23, it is also possible insert the retaining ring 34 between the neck 35 and the extension 32. there the retaining ring 34 has a larger outer diameter than one between the extensions 32 forming inner dimension in the vertical direction to Longitudinal central axis 21. Likewise, the diameter of the opening 39 of the retaining ring 34 smaller than a largest outer dimension of the extension 35 in a plane perpendicular to the longitudinal central axis 21. However, this outer dimension of the sealing device 24 is so dimensioned that this at least twice the wall thickness 13 of the receptacle 5 is larger than the inner dimension 14 of the inner cross section 18 and thus the interior 10. After the extension 33, which forms the coupling part 28, has an inner opening width which is essentially the inner dimension 14 of the receptacle 5 corresponds to a very good retention of the Approach 35 in the cap 23 and a good seal between the interior 10 of the receptacle 5 and the one surrounding the receptacle 1 The atmosphere.

Above all, the tightness of the closure device 8 for the open end face 22 the receiving device 1 is further improved if an outer diameter the sealing device 24 in the area of its sealing surface 36 in the relaxed state outside of the receptacle 5 is larger than the inner dimension 14 of the receptacle 5th

Furthermore, in the relaxed, unmounted state, there is a longitudinal or vertical extension of the extension 35 of the sealing device 24, in the direction of the longitudinal central axis 21 seen, greater than a distance of a groove-shaped recess between the two Extensions 32, 33 and possibly less a thickness of the retaining ring 34 by the previously described dimensional differences between the groove-shaped recess and the length dimensions of the neck 35 and the thickness of the retaining ring 34 there is a bias of the approach 35 between the two extensions 32, 33. This simultaneously causes compression and pretensioning of the sealing device 24 in relation to the cap 23. This may also result in a tight fit of the retaining ring 34 and also a tight fit of the two end faces of the Approach 35 in the area of the two extensions 32, 33.

It is also advantageous if the cap jacket 26 as a truncated cylinder jacket or truncated cone jacket is formed, whereby an overlap of the cap jacket 26 is guaranteed in the area of the upper end face 22.

Furthermore, it can prove to be advantageous if in the area of the open end face 22 of the receptacle 5 at least two guide extensions 40, 41 are arranged are protruding over the outer circumference 17 of the cylindrical receptacle 5. However, any other number of guide extensions 40, 41 is possible, this having on an inner surface of the receptacle 5 facing the Cap 23 arranged and over its surface in the direction of the longitudinal central axis 21 projecting guide webs 42, 43 cooperate. The number is as well e.g. uniform, angularly offset division of the guide webs 42, 43 over the extent of the number of guide projections arranged on the receptacle 5 40, 41 dependent. These guide extensions 40, 41 act on the inside of the cap jacket 26 arranged guide webs 42, 43 together, whereby it is made possible that when the cap 23 is pushed open in the direction of the longitudinal central axis 21 of the receptacle 5 in the direction of the open end face 22 of the same and a corresponding clockwise rotation of the guide webs 42, 43 run on the guide extensions 40, 41 and that due to the combined Rotational and longitudinal movement due to the guidance of the guide webs 42, 43 along the Guide extensions 40, 41, the sealing device 24 with its sealing surface 36 in the Interior 10 of the receptacle can be inserted or inserted.

As can also be seen from an overview of FIGS. 1 and 2, the receiving device has 1 at the end region 7 facing away from the end region 6 Closure device 9, which consists of a pierceable sealing body 44 a pierceable, highly elastic and self-sealing material, in particular a rubber, pharmaceutical rubber, silicone rubber or bromobutyl rubber and a holding element 45 for holding the sealing body 44 on the receptacle 5 is formed is. On the one hand, the holding element 45 has means for coupling, such as, for example one or more coupling parts 46 of a coupling device 47 between the Holding element 45 and the receptacle 5 and on the other hand means for holding, such as one or more holding parts 48 of a holding device 49, the Sealing body 44 in a sealing position in a tapering towards the interior, opposite to the sealing body 44 formed opening 50. Here is the Form surface of the opening 50 in its surface quality as a sealing surface.

The sealing body 44 is conical, in particular as a truncated cone with a cone angle 51 and has an end face 52 facing the holding element 45 with a diameter 53 and one facing away from it, the interior 10 of the receptacle 5 further front end 54 with a smaller diameter 53 Diameter 55 on.

The receptacle 5 has the previously described, opposite to the cone angle 51 of the sealing body 44 formed opening 50 in its end region 7, in which the sealing body 44 for closing or sealing the interior 10 opposite the external atmosphere can be used and by means of the holding element 45 in this sealing position is held securely. For this purpose, the opening 50 faces the interior 10 opposite side of the receptacle 5 a diameter 56 and a diameter 57 in the area of the interior 10. The is preferred Diameter 55 of the front end 54 of the sealing body 44 is larger than the smallest diameter 57 of the opening 50 receiving the sealing body 44. Furthermore, the largest Diameter 53 of the sealing body 44 larger than the largest diameter 56 also the opening 50 receiving the sealing body 44. This ensures, on the one hand, that the end face 54 of the sealing body 44 facing the interior 10 does not protrudes through an inner bottom surface 58 of the receptacle 5 into the interior 10 thereof and on the other hand, that a further end face 59 in the end region 7 of the receptacle 5 not for contact with a surface of the interior 10 facing the Holding element 45 comes, which is between the end face 59 and the inner Surface of the holding element 45 forms a distance 60. This distance 60 serves to the fact that there may be manufacturing inaccuracies between the opening 50 of the receptacle 5 and an outer sealing surface 61 of the pierceable Sealing body 44 for a secure and sealing contact of the sealing surface 61 comes in the opening 50. This can also be a slight preload of the sealing body 44 in cooperation with the holding element 45 in the direction of the interior 10 can be achieved.

This sealing contact of the sealing body 44, in particular the sealing surface 61 in the Opening 50 effect the holding means of the holding element already described above 45, which so far from the outside in a central central region of the holding element 45 protrude that these are the largest when placed on the receptacle 5 layer Diameter 53 of the sealing body 44 in the direction of the central region, ie in the direction protrude from the longitudinal central axis 21 in the radial direction. The holding device can 49 from individual holding parts 48 distributed over the circumference and / or by one End wall 62 of the holding element 45 with one arranged in the central region thereof Opening 63 may be formed. This opening 63 has an opening width 64 which is at least smaller than the largest diameter 53 of the sealing body 44. This is a secure mounting of the sealing body 44 with respect to the receptacle 5 in the latter used position guaranteed safely.

In this embodiment of the holding element 45 shown here, it is designed like a cap and has the previously described means for coupling to the receptacle 5 on. The coupling parts 46 forming these can for example be formed by holding, locking or snap arms, which in the radial direction of the holding element 45 are elastically resettable, deformable. It is can also be seen that the coupling parts 46 of the coupling device 47 at the position of the receptacle 5 on the outer dimension 19 or over the outer circumference 17 of the receptacle 5 in the direction of its longitudinal central axis 21 protrude. Here, a maximum outer dimension 65 of the holding element 45 the same and / or slightly larger than the maximum outer dimension 19 of maximum outer cross section 20 of the receptacle 5. This ensures that the outer dimension 19 of the receiving device 1 in the end region 7 despite the arrangement of the closure device 9, no or only a slight enlargement of the outer dimension 65.

To form the coupling device 47, the receptacle 5 has in it End region 7 has a groove 66 which is approximately opposite to coupling part 46, which, for example, all around the entire outer circumference 17 and / or through Groove parts 67 distributed over the circumference are formed in segments. The arrangement and Formation of the groove 66 or the individual groove parts 67 or recesses, depressions etc. depend on the design of the holding element 45. But it is independent of which also possible that the coupling device 47 by over the circumference distributed arranged, preferably conically tapering receiving bores is formed, which with individual counter-trained, cone-like Interacting coupling parts 46 on the holding element 45. But it would also be possible the coupling device 47 between the holding element 45 and the receptacle 5 in such a way that, for example, on the receptacle 5 above The outer circumferential projecting coupling parts are arranged, which have a groove-shaped Arrangement or groove parts of the holding element 45 cooperate. This is likewise again the formation of the coupling device 47 between the holding element 45 and the receptacle 5 guaranteed.

As can also be seen from the illustration in FIG. 1, the receptacle has 5 in its end region 7, in which the opening 50 for inserting the sealing body 44 or for filling or filling the interior 10, one opposite the wall thickness 13 of the container wall 12 greater wall thickness, which in this end region 7 the formation of the opening 50 or the coupling device 47 can be done. Furthermore, it is advantageous if the coupling device 47 on Outer periphery 17 of the receptacle 5 in a position covering the opening 50 is arranged, which results in a strength-favorable design of the end region 7, due to the greater wall thickness in this section, can be achieved.

Furthermore, the separating device 11 is shown in the interior 10 of the receptacle 5. which consists of a sealing device 68, in the present exemplary embodiment a sealing element 69 made of a first material and a support body 70 made of a second, different material is formed. The sealing element 69 of the Sealing device 68 is preferably annular in a side wall 71 of the supporting body 70 arranged recess 72 arranged and projects beyond the side wall 71 of the support body 70, preferably circumferentially over its circumferential direction. Advantageous it is when the material for the sealing element 69 is resiliently deformable is and e.g. through a silicone rubber, pharmaceutical rubber, bromobutyl rubber, Rubber, a gel or an elastomeric plastic is formed. For the sealing element 69 can handle a wide variety of materials or cross-sectional shapes are used, e.g. an O-ring or flange ring or a circumferential one Sealing lip, a thin-walled web or a thin-walled lamella as a sealing element 69, e.g. can be used in grooves and / or clamping areas or the like. It is but also possible, the sealing element 69 via a molding process on the support body 70 to fix.

Furthermore, it is advantageous if the second material of the support body 70 is liquid-tight is and a higher density and / or hardness than the first material of the sealing element 69 and, if appropriate, with additives or fillers provided plastic, e.g. a thermoset, a crystal clear polystyrene and the like is. Furthermore, the support body 70 should have a gas permeability that the Gas penetration almost prevented at least in a period of 72 hours. It can also prove to be advantageous if the total weight of the support body 70 and / or the separating device 11 can be changed, for example is possible, the separating device 11 and / or the support body 70 to different Media 3, 4 of the mixture 2 to be separated exactly match. It is also advantageous if the gas permeability of the sealing element 69 is at least equal to or greater than that of the support body 70.

As already described above, the separating device 11 consists of at least one sealing element 69 made of a first material and the support body 70 made of a different second material. In order to achieve an exact physical separation process of the two media 3, 4 of the mixture 2 during the centrifuging process, the specific weight or the density of the second material of the support body must on the one hand be smaller than the higher specific weight or the density of one of the separators 11 to be separated medium 3, 4 and on the other hand be greater than the lighter specific weight or the density of one of the medium 3, 4 to be separated by the separating device. It has proven to be advantageous if, for example, the density of the support body 70 is between 1. 03 g / cm ³ and 1.06 g / cm ³ , preferably 1.05 g / cm ³ .

Depending on the mixture 2 to be separated from the different media 3, 4 or components it can prove to be advantageous if at least partial areas or the entire inner surface 15 of the interior 10 is provided with a coating 73 is, for example, the sliding movement of the separator 11 during to support the separation process and / or a chemical and / or physical Influencing the mixture 2 or the like. In a preferred system of the support body 70 on one of the closure devices 8, 9 can at least the between the separating device 11 and the opposite end region 6, 7 Surface 15 may be provided with this coating 73, which for example designed to be detachable or detachable from the surface 15 on contact with the mixture 2 is and e.g. used simultaneously to fix the separating device 11 become.

Furthermore, with locking devices 8, 9 before using the receiving device 1, that is, before filling the same, evacuated or reduced to a lower air pressure than the external air pressure be to make it easier to suck the mixture 2 to be filled into the interior 10 to facilitate. For a two-sided wetting of the separating device 11 to avoid the filling process, it is advantageous if the separating device 11 close to one of the two closure devices 8, 9, in particular in contact with one of these two is arranged.

3 is a partial area of the receiving device 1 on an enlarged scale shown, the same reference numerals as in FIGS. 1 and 2 being used for the same parts become. This embodiment of the closure device 9 shown here, consisting from the holding element 45 and the pierceable sealing body 44 differs from the previously described embodiments, these being different Embodiments of course form independent solutions as well as with other described embodiments in other figures can be combined.

The end region 7 of the receptacle 5 in turn has a conical direction of the interior 10 has a tapering opening 50 into which the sealing body 44 is used for the sealing position in the same. In this embodiment it is shown that the sealing body 44 by a multi-layer component from each other in particular different materials, such as from layers 74 to 76, is formed. For example, the two can be spaced apart Layers 74, 76 of a softer and more suitable material for the seal and the layer 75 can be formed from a material which is harder for this purpose, for example serve as a base course. Furthermore, it is possible that the one facing the holding element 45 Front end 52 of the sealing body 44 with a concave shown in simplified form Recess 77 is formed or arranged in this. Regardless, for example the end face 52 of the sealing body opposite the end face 52 44 be completely concave. By combining the concave The depression 77 or the completely concave front end 54 can be Piercing thickness of the sealing body 44 to different circumstances, such as adjust a needle diameter.

The holding element 45 is in turn cap-shaped and has in its Sealing body 44 facing end wall 62 in turn the opening described above 63 to ensure puncturing through the sealing body 44. The holding device 49 between the holding element 45 and the sealing body 44 can according to one of the described embodiments.

Starting from the end wall 62 of the holding element 45 is in its outer edge area an all-round extending in the direction of the receptacle 5 Bund 78 arranged and connected to this. This collar 78 can for example form part of the coupling device 47, in particular a coupling part 46 and expandable and elastic due to the selected material of the holding element 45 be resettable. In its end region facing away from the end wall 62 of the federal government 78, this can be done with at least a part of the federal government 78, collar-like coupling element 79 projecting inwards in the circumferential direction be equipped. Of course, it is also possible for the coupling element 79 as well as to arrange the collar 78 continuously on the holding element 45, so the coupling force between the receptacle 5 and the holding element 45 and in consequently, the sealing force between the sealing body 44 and the opening 50 of the To control receptacle 5. The coupling element 79 of the coupling device 47 can in turn engage in the previously described groove 66 of the receptacle 5, the groove 66, as already described above, again running all the way round or can optionally be arranged only in certain areas.

But it is also possible that the sealing body 44 attached to the holding element 45, glued or by a molding process or by a two-component injection molding is produced or connected to this. Irrespective of this, the Sealing body 44 and the holding element 45 made of one component, that is to say in one piece be and preferably from a highly elastic and self-sealing material, in particular from a rubber, pharmaceutical rubber, silicone rubber or bromobutyl rubber consist.

To a rolling movement of the entire recording device 1 in its assembled To avoid the condition, it is possible, as shown in dashed lines on the holding element 45 Lines is indicated schematically on the holding element 45 or on one of its coupling parts 46 to arrange the coupling device 47 at least one stop rib 80, which protrudes beyond the outer circumference 17 of the receptacle 5 is. By arranging one or more stop ribs 80 is thus secured avoided that a receiving device 1 in use after whose filling can fall onto the floor, for example, from a storage surface, which causes unwanted vibrations or unwanted mixing of the interior 10 filled mixture 2 and breaking or loosening one of the closure devices 8, 9 is safely avoided.

4 shows the separating device 11 in an enlarged, diagrammatically simplified illustration shown how this has already been described in FIG. 1, wherein for same parts same reference numerals are used.

The separating device 11 consists of the sealing device arranged on the support body 70 68, which in this embodiment is again formed by the sealing element 69 is. The sealing element 69 is arranged in the region of the peripheral side wall 71 and protrudes above it on a central longitudinal axis 81 of the support body 70 opposite direction. Furthermore, the support body 70 preferably points perpendicular to the End faces 82, 83 aligned and spaced apart from one another along the longitudinal center axis 81 on which, in cooperation with the side wall 71, the support body 70 in its Define the room shape. In this exemplary embodiment, the support body 70 has an in Round cross-sectional shape seen in the direction of the central longitudinal axis 81 with an outer dimension 84 on. As already described above, the two end faces 82, 83 are Seen in the direction of the central longitudinal axis 81, spaced apart from one another at an overall height 85 arranged, the recess 72 for the sealing element 69 in its middle preferably centrally to the overall height 85, ie at distances 86, 87 from the two end faces 82, 83. is arranged. But it is of course also possible to set the distances 86, 87 different from each other to offset the recess 72 and thus the sealing element 69 in the direction of the central longitudinal axis 81. whereby the center of gravity of the separator 11 with respect to the arrangement of the sealing element 69 on the support body 70 is changeable. This can vary depending on the application the chosen physical separation type.

For the sake of completeness, it should be pointed out that the support body 70 with its Sealing elements 69 all have possible cross sections for the use of the same can, this cross section the cross section of the inner surface 15 of the Receiving device 1 must correspond to achieve the desired application.

Due to the previously described outer dimension 84 and the overall height 85 of the Support body 70 can be determined a diagonal corner dimension 88 for the support body 70, which must in any case be larger than the inner dimension 14 or as the inner cross section 18 of the receptacle 5 to tilt the support body 70 to avoid secured a transverse plane to the central longitudinal axis 81. This is before especially during and after the physical separation process of the two media 3, 4 of the Mixtures 2 of great importance, since otherwise the media 3, which are separated from one another, 4 of the mixture 2 after the completion of the separation process not by the separation device 11 are separated from each other in a sealed manner.

This corner dimension 88 is determined between an intersection 89 of the lower one here End face 82 with the side wall 71 and the intersection 89 diametrically opposite intersection 90 between the lower end face 82 opposite end face 83 and which is preferably centered on the central longitudinal axis 81 aligned side wall 71. The side wall 71 is parallel to the overall height 85 aligned, the in the region of the peripheral side edges of the side wall 71 two end faces 82, 83 each aligned perpendicular to the height 85 Level are arranged.

This diagonal corner dimension 88 in the case of, for example, a round support body 70 can be deduced from the root of the sum of the Pythagorean theorem Squares of the outer dimension 84 and of the height 85 running perpendicular to it determine or calculate. This diagonal corner dimension 88 must in any case be larger than the inner dimension 14 in the perpendicular to the longitudinal central axis 81 aligned inner cross section 18 of the separating device 11 accommodating Interior 10 of the receptacle 5. This is an inclination of the Separating device 11, that is, an angular orientation of the central longitudinal axis 81 of the Carrying body 70 possible with respect to the longitudinal central axis 21 of the receptacle 5, however, assured a complete tipping and thus a sealless condition between the sealing device 68 and the inner surface 15 of the receptacle 5 is avoided.

5 is a partial area of the receiving device 1 with that in the receiving container 5 arranged separator 11 on a larger scale during the physical Separation process of the mixture 2 from the media 3, 4 shown, being the same Parts the same reference numerals as in Figs. 1 to 4 are used. Essentially corresponds to the separating device 11, consisting of the support body 70 and the sealing device 68 arranged thereon with sealing element 69, that described above Embodiment.

The receptacle 5 has the inner dimension perpendicular to its longitudinal central axis 21 14, the separating device due to the centrifugal forces that occur 11 with the sealing element 69 arranged thereon against the inner surface 15 is pressed. Furthermore occurs due to the different previously described Materials of the support body 70 to the sealing element 69 only a deformation of the sealing element 69 on, as is also indicated schematically. It is in the left part of the separating device 11 of the support body 70 in its rest position dashed lines shown. The centrifugal force causes an offset of the central longitudinal axis 81 of the support body 70 with respect to the longitudinal central axis 21 of the receptacle 5 by a maximum deformation path 91, whereby in the opposite area the separating device 11, the sealing element 69 with respect to the inner surface 15 loses its sealing system in some areas and there is a gap in this area 92 with a width 93 in the direction measured perpendicular to the longitudinal central axis 21 forms. This is formed between the sealing element 69 and the inner surface 15 Gap 92 serves this purpose. those components during the physical separation process of the mixture 2 with a lower specific weight or less Density, such as medium 3, of those components of the mixture a higher specific weight or density, such as that Medium 4, spatially separate from each other and thus a passage possibility of the to allow physically lighter portion of the mixture 2 through the gap 92. This takes place starting from a collecting space 94 in an area between the End face 82 of the support body 70 and the bottom surface 58 in the end region 7 of the receptacle 5 in a between the end face 83 and the closure device 8 arranged separation room 95. After the completion of the physical separation process and the associated withdrawal of those acting on the sealing element 69 The sealing element 69 takes centrifugal forces because of its resiliently resettable Properties in turn are an all-round sealing system on the inner surface 15 of the receptacle 5, but between the two media 3, 4.

It is essential that the maximum deformation path 91 of the sealing device 68, in particular of the sealing element 69 in perpendicular to the central longitudinal axis 81 of the sealing element 69 extending direction in the area projecting beyond the supporting body 11 is greater than a dimensional difference of the sealing element 69 in relation to the longitudinal central axis 21 vertical direction in a relaxed rest position and in the interior 10 of the Receiving container 5 inserted, pre-stressed position.

FIG. 6 shows a further possible embodiment which may be independent in itself of the holding element 45 shown in view and on an enlarged scale, the same reference numerals as in FIGS. 1 to 5 being used for the same parts. Of course, the embodiment described here, in particular the End wall 62 can also be used in the cap 23 of the closure device 8 and be arranged instead of the extensions 32. If necessary, this is also a thing of the past of the retaining ring 34 possible, whereby the approach 35 directly to the interior 10 facing inside of the cap 23 comes to rest.

The holding element 45 in turn has the holding device in the region of the end wall 62 49 for the pierceable sealing body 44 for sealing engagement thereof the opening 50 of the receptacle 5. For example, the holding device 49 as a circular ring with the one arranged in its center or central region Opening 63 may be formed, which via webs 96 with the in the range of the maximum Outer dimension 65 arranged coupling device 47 is connected. In the same number are openings between the webs 96, seen in the radial direction 97 arranged, which is in the circumferential direction between the individual webs 96 extend. Both the number of webs and their arrangement and Dimensioning and associated with that of the openings 97 freely selectable, wherein the angular division of the individual webs 96 or openings 97 to one another symmetrically can be done. The opening 63 in the center of the holding element 45 serves to an unimpeded piercing through the sealing body 44 into the interior 10 of the To ensure receiving device 1.

FIG. 7 shows a further embodiment, which may be independent a separating device 11 with part of the receiving device 1 is shown, the same reference numerals being used for the same parts as in FIGS. 1 to 6 become.

The separating device 11 shown here in turn consists of the support body 70 and the sealing device 68 arranged thereon, which in the present exemplary embodiment from two in the direction of the central longitudinal axis 81 of the support body 70 from each other spaced sealing elements 69 is formed.

The support body 70 in turn has the outer dimension 84, with its center the central longitudinal axis 81 is arranged to run. This outer dimension 84 is delimited by the side wall 71, which preferably runs all around, on which the two sealing elements 69 are also arranged. These sealing elements 69 can in turn be inserted into the recesses 72 of the support body 70, whereby the sealing elements 69 protrude 98 beyond the parallel to the central longitudinal axis 81 have aligned side wall 71 all around, which preferably has a uniform Has value.

The support body 70 is further aligned by the two perpendicular to the central longitudinal axis 81 End faces 82, 83 limited in its longitudinal extent, whereby between this again forms the overall height 85. In the double arrangement shown here the sealing elements 69 for the sealing device 68 is in each case a means of the recesses from the end faces 82, 83 arranged at an edge distance 99. 100, whereby a distance 101 is formed between the two sealing elements 69. Through this at least double arrangement of the sealing elements 69 at a distance 101 from each other in the direction of the central longitudinal axis 81 is a tilting of the entire separating device 11 safely avoided during the physical separation process.

As can also be seen from this illustration, the separating device 11 has a maximum cross-sectional dimension 102 in the area of the sealing elements 69 in a vertical to the central longitudinal axis 81 arranged plane, which results from the outer dimension 84 of the support body 70 and the double projection 98 of the sealing element 69 trained over the support body 70. This cross-sectional dimension 102 is relaxed and not in the position used in the interior 10 at least the same or to some extent larger than the inner dimension 14 in one as well Plane of the receptacle 5 oriented perpendicular to the longitudinal central axis 21. Due to the preferably slight differences in diameter, there is a sealing Contact of the sealing elements 69 on the inner surface 15 of the receptacle 5th

However, it is of course also possible to determine the number of sealing elements 69 for the Sealing device 68 to choose arbitrarily, but it is also possible independently is the cross-sectional shape of the individual sealing elements 69 over that shown here to train round embodiment differently. The sealing elements 69 can for example but also through sealing lips, sealing beads and sealing lugs in a wide variety Embodiments can be formed. But it would be possible that at least a sealing element of the sealing device 68 to that aligned parallel to the height 85 Central longitudinal axis 81 is arranged eccentrically. But it would also be possible that two or more sealing elements 69 of the sealing device 68 to the central longitudinal axis 81 of the support body 70 are arranged eccentrically to the opposite. As beneficial can prove if, for example, a center of gravity of the support body 70 in one the medium 3, 4 of the mixture 2 with the higher specific weight or the end region assigned to the higher density.

8 is a possible and possibly independent embodiment a further development of the separating device 11 and the closing device 8 for the receiving device 1 on an enlarged scale and schematically simplified Representation shown, the same reference numerals as for the same parts 1 to 7 can be used. Of course, instead of the one shown here double arrangement of the sealing elements 69 each embodiment described above Find use. Furthermore, it is also possible to use the bracket shown here between the separating device 11 and the closure device 8 also analogously to be transferred to the further closure device 9.

As already described above, it is necessary to close the separating device 11 of the two closure devices 8. 9, in particular with one of its end faces This is applied to the interior 10 in before the mixture 2 is filled to keep their area until the start of the separation process. For that result different ways, like this in this and the following figures is described in more detail. In the embodiment shown here is in the range between the end face 83 of the support body 70 and the face thereof Sealing surface 37 of the sealing device 24, a holding device 103 is arranged, around the separator 11 during the assembly process, throughout Storage period of the receiving device 1 and during the filling process of the Interior 10 with the mixture 2 up to the start of the centrifugation process in to hold this position. Furthermore, it can be seen in the arrangement shown here that the central longitudinal axis 81 of the separating device 11 is centered or congruent to the longitudinal center axis 21 of the receptacle 5 is arranged.

In the present exemplary embodiment, a holding device 103 consists of at least an approximately spherical holding extension 104 in the region of the central longitudinal axis 81 of the support body 70 as well as at least one of counterparts Holding receptacle 105 in the central region of the longitudinal central axis 21 of the sealing device 24. The shape of the mounting device 103 or its parts is only exemplary here shown, although of course any other form of training is possible. Of course, the holding extension 104 on the sealing device can also 24 and the holding receptacle 105 can be arranged on the support body 70. It is essential that the holding extension 104 in the holding receptacle 105 with a certain holding force is supported, which is sufficient, the separating device 11 in its position in relation to the closure device 8 hold securely until the start of the centrifugation process. The Bracket device 103 must reach the separation device when reaching a certain centrifugal force 11 release, whereby this due to their own weight and the possibly on this acting centrifugal force in the direction of an arrow 106 starting from the closure device 8 in the direction of the further closure device 9 is moved. The holding extension 104 preferably projects beyond that end face 83, on which this is arranged, molded, etc.

Irrespective of this, it is also possible, for example the mounting device 103 between the separator 11 and the receptacle 5 and this, for example, by at least one over the inner surface 15 of the receptacle 5 projecting in the direction of the longitudinal central axis 21 extension 107 holders. This extension 107 can be designed in a wide variety of ways, for example by individual extensions 107 distributed over the circumference or by one in the direction the longitudinal central axis 21 projecting and continuous, bundle-shaped Extension 107 may be formed. The necessary holding force can either be via the Number of individual extensions 107 and, if appropriate, over their length of the projection can be influenced and controlled in the direction of the longitudinal central axis 21 and thus be matched to the different operating conditions. Of course but is also a combination of the mounting device described above 103 between the separating device 11 and the sealing device 24 and between the separator 11 and the receptacle 5 possible.

9 shows a further possible and possibly independent training the mounting device 103 between the separator 11 and the Receiving container 5 in the area of the closure device 8 of the receiving device 1 shown on an enlarged scale and schematically simplified, again the same reference numerals as in FIGS. 1 to 8 are used for the same parts.

In this embodiment shown here, the receptacle 5 has in its End region 6, in which the sealing device 24 of the closure device 8 is inserted, starting from the open end face 22 of the receptacle 5 in Direction of the longitudinal central axis 21 over a length 108 relative to the inner dimension 14 larger inner dimension 109 in a perpendicular to the longitudinal central axis 21 level. Due to the dimensional difference between the two inner ones Dimensions 14 and 109 and the larger compared to the inner dimension 14 outer cross-sectional dimension 102 of the separating device 11 occurs during the Assembly process, the entire storage period up to the start of the centrifugation process to a supporting system of one of the sealing elements 69 of the separating device 11 on a shoulder-shaped attachment 110 forming the holding device 103 Area of the inner surface 15 of the receptacle 5. This bundle-shaped or shoulder-shaped approach 110 is formed by the previously described dimensional difference two inner dimensions 14 and 109 from each other. This approach 110 can for example by reducing the wall thickness 13 in the area of the end face 22 or by increasing the same following the length 108.

When choosing the inner dimension 109, it should be borne in mind that this is still the case the sealing surface 36 of the sealing device 24 in a secured sealing system on the inner surface 15 of the receptacle 5 in the end region 6 thereof comes. It is advantageous if the difference in dimensions between the inner dimensions 14 and 109 is between 0.1 mm and 4.0 mm, preferably 1.0 mm. Furthermore can a dimension of the extension 107 or extension projecting beyond the inner surface 15 110 between 0.01 mm and 2.0 mm, preferably 0.5 mm.

10 is one of the possible configurations of the receiving device 1 according to the separation of the two media 3, 4 of the mixture 2 shown, wherein for same parts the same reference numerals as in Figs. 1 to 9 are used. The For the sake of simplicity or for the sake of clarity, only one was possible Embodiments of the different components described above or Assemblies shown, although it is of course possible, these different Embodiments analogously to the receiving device 1 shown here transfer.

The receiving device 1, consisting of the receiving container 5, the two in its end regions 6. 7 arranged locking devices 8, 9 and in Interior 10 arranged separator 11 is shown in that operating state, in which the mixture 2 already spatially from one another in its two media 3, 4 is separated. So the mixture 2, e.g. Blood in a serum medium 3 - and a plasma medium 4 - divided.

The entire receiving device 1 is usually centrifuged in a preferably vertical position of the longitudinal central axis 21, preferably the Closure device 8 at the upper end of the receptacle 5 and the closure device 9 is arranged at the lower end of the receptacle 5.

As already described above, the interior 1 () of the receptacle 5 is in the Ready-to-operate version on a sub-atmospheric pressure Pressure is evacuated, with the separating device 11 also being in the vicinity or adjacent to one of the closure devices 8, 9, as in the present Embodiment is arranged on the closure device 8. The filling of the Interior 10 takes place here in the area of the pierceable sealing body 44 of the closure device 9. As can be seen from FIG. 1, the receiving device 1 shown there after the filling process and immediately before the centrifugation process.

As can be seen better from FIG. 10, the separating device 11 is located between the two separate media 3, 4 of the mixture 2, wherein during the Centrifuging the specifically lighter medium 3 from the specifically heavier Medium 4 is physically separated, as is already the case in FIG. 5 for only one Sealing element has been described. Due to the weight of the separator 11 and the selected specific weight or the previously described The density of the same drops into the medium 3 and then floats on specifically heavier medium 4. A deeper sinking of the separation device 11 in the medium 4 is due to the physical properties described above not possible, causing the separator 11 after the centrifugation has ended process and the reshaping of the sealing device 68 again with its sealing elements 69 sealingly against the inner surface 15 of the receptacle 5 comes and so a new mixing of the two media 3, 4 of the mixture 2 is safely avoided. Following this, it is possible, for example, to do this specifically lighter medium 3 from the interior 10 of the receptacle 5 by opening the closure device 8 and possibly the heavier medium 4 Opening the closure device 9 also separately from the interior 10 refer to.

Due to the design of the separating device 11, it is possible, for example, too volumes of the mixture 2 filled differently into the interior 10 from one another to separate without an exact filling quantity or filling height in the Receiving container 5 must be observed when filling. The separation process of the Both media 3, 4 must continue until it is ensured that the separating device 11 is arranged between the two media 3, 4 and on the physical heavier medium 4 floats.

In Fig. 8 is also shown schematically that the mounting device 103 e.g. also by one applied to the inner surface 15 of the receptacle 5 Coating 111 can be formed, which the separating device 11 to Start of the centrifuging process in the vicinity of one of the closure devices 8, 9 holds. It is possible to design the coating 111 such that it during the entire storage period of the receiving device 1 until the filling process serves as a holding device 103 and only directly at the beginning of the centrifuging process loses its holding effect for the separating device 11 and e.g. also afterwards serves as a lubricant for the separating device 11 during its movement, since it softens or through the liquid introduced into the receptacle 5 is dissolved or rinsed off. The coating 111 can be applied to the entire surface of the inner surface 15 as well as applied to it only in certain areas.

FIG. 11 shows a further embodiment, which may be independent a separating device 11 with a part of the one forming the receiving device 1 Receiving container 5 shown, again the same reference numerals for the same parts as used in Figs. 1 to 10. To a variety of different To be able to represent training options for the sealing device 68 and to avoid multiple representations, these were in a common figure, however shown in different positions.

The separating device 11 shown here in turn consists of the support body 70 and the sealing device 68 arranged thereon, which preferably consists of at least one sealing element arranged centrally to the central longitudinal axis 81 of the support body 70 69 is formed.

The support body 70 in turn has the outer dimension 84, with its center the central longitudinal axis 81 is arranged. This outer dimension 84 is represented by delimits the side wall 71 which preferably runs all around, on which also the different sealing elements 69 can be arranged. These sealing elements 69 can either again in differently designed recesses 72 of the Support body 70 used or held on the support body 70, the sealing elements 69 a projection 98 aligned over the parallel to the central longitudinal axis 81 Have side wall 71 all around, which preferably has a uniform value.

The support body 70 is further aligned by the two perpendicular to the central longitudinal axis 81 End faces 82. 83 limited in its longitudinal extent, whereby between this again forms the overall height 85. Through a possible multiple arrangement the sealing elements 69 on the support body 70 in the direction of the central longitudinal axis 81 a tilting of the entire separation device 11 during the physical separation process safely avoided.

As can also be seen from this illustration, the separating device 11 has a maximum cross-sectional dimension 102 in the area of the sealing elements 69 in a vertical to the central longitudinal axis 81 arranged plane, which deviates from the outer dimension 84 of the support body 70 and the double projection 98 of the sealing element 69 composed over the support body 70. This cross-sectional dimension 102 is in the relaxed and not used in the interior 10 position at least the same or to some extent larger than the inner dimension 14 in one too Plane of the receptacle 5 oriented perpendicular to the longitudinal center axis 21 due to the preferably slight differences in diameter, this leads to a sealing contact of the sealing elements 69 on the inner surface 15 of the receptacle 5th

The sealing element 69 shown in the upper left area of the support body 70 has an approximately circular base body with an arranged thereon, protruding in the direction facing away from the central longitudinal axis 81 112, which has a thickness of 113 on that facing away from the central longitudinal axis 81 Direction is preferably continuously decreasing. The preferred voluminous The basic body of the sealing element 69 can be formed in the groove-shaped recess 72 may be used in the support body 70. Of course there is also a multiple arrangement of the sealing element 69 possible to form the sealing device 68.

In the upper right area of the support body 70 is another possible training of the sealing element 69 shown, which consists of an approximately cylindrical Base body 114 and at least one, but preferably several extensions 112, which on the side of the separating device facing away from the central longitudinal axis 81 11 protrude, is formed. The extensions 112 can in turn also with a relatively small thickness 113 in the direction parallel to the central longitudinal axis 81 be and through preferably all-round, thin webs, lamellae, sealing lips or the like. It is also shown here that the body 114 in the region of the side wall 71, at least one extension 115 is arranged, which extends from the side wall 71 in the direction of the central longitudinal axis 81. Seen over the circumference, this approach 115 can only in certain areas and with respect to one another be staggered or continuous. It goes without saying seen a multiple arrangement of the approach 115 in the direction of the central longitudinal axis 81 possible, this approach 115 in turn a correspondingly dimensionally trained Recess 72 in the support body 70 is assigned. This makes it possible Sealing element 69 against axial movement in the direction of the central longitudinal axis 81 in Secure relation to the support body 70, whereby the sealing device 68, which in the present embodiment is formed by the sealing element 69 in its Position relative to the support body 70 is fixed. These previously described and interacting Components provide means for holding between the support body 70 and the sealing device 68.

Another possible design of the sealing device 68 is in the lower right area of the support body 70 shown, which in this embodiment is the immediate previously described sealing element 69 is very similar. The individual point Extensions 112 have an even smaller thickness 113 compared to those described immediately above Extensions 112 on, creating an even better seal of the two Media 3, 4 to be separated from one another can take place after the separation process. The individual extensions 112 are again arranged on a common base body 114, here the base body 114 on its side wall 71 of the support body 70 facing surface by means of a schematically indicated adhesive layer 116 is supported on the support body 70. The formation and arrangement of the adhesive layer 116 depends on the choice of materials from which the support body 70 or the Sealing device 68 is formed, and can of course be chosen freely. However, it is also possible to use an adhesive or press fit instead of the adhesive layer 116 between the sealing element 69 and the support body 70 to provide a turn to achieve secure positioning of the sealing element 69 in relation to the support body 70.

In the lower left area of the support body 70 is a further training and arrangement options of the sealing element 69 of the sealing device 68 on the support body 70 shown. The sealing element 69 can be similar to that described immediately above Be formed sealing element 69 and in turn from the base body 114 and the one arranged thereon and facing away from the central longitudinal axis 81 Be projecting extensions 112 are formed. To fix the position of the sealing device 68 in relation to the support body 70 in the direction of the central longitudinal axis 81, is the base body 114 a dimensionally coordinated recess 72 assigned in the support body 70, in which the base body 114 is inserted.

Because of the previously described embodiments, it is possible to use the Manufacture support body 70 or the sealing device 68 in a separate manufacturing process and only then join them together to form the common separating device 11. But it is also possible to have the sealing device 68 in its own To form, spray or glue work on the support body 70. Furthermore, can the manufacture of the separation device 11 described above to the most varied Way, taking place instead of the previously described separate Production and subsequent assembly is also possible, the separator 11 in a co-injection molding or in a coextrusion process and one any combination of the manufacturing processes described above. It is essential. that between the sealing element 69 and the support body 70th Means for holding are arranged, which fix the position of the two in relation to one another Secure components to each other.

A great advantage over previously known recording devices, which for Separation of different media are used, is also that due to the weight design of the separation device 11 a floating between the separate 3, 4 media takes place, without thereby an exact filling quantity the media 3, 4 to be separated must be observed before the centrifugation process got to.

Of course, it is possible within the scope of the invention via the exemplary embodiments shown to change the arrangement of the individual elements or can also be combined differently. Finally, for the sake of order, it should be noted that for better understanding the function and design of the receiving device according to the invention from the receptacle, the separating device and the closure devices, many parts of it are shown schematically and disproportionately enlarged have been.

REFERENCE NUMBERS

1

recording device

2

mixture

3

medium

4

medium

5

receptacle

6

end

7

end

8th

closure device

9

closure device

10

inner space

11

separating device

12

container wall

13

Wall thickness

14

dimension

15

surface

16

surface

17

outer periphery

18

cross-section

19

dimension

20

cross-section

21

Longitudinal central axis

22

front

23

cap

24

sealing device

25

sealing plug

26

cap casing

27

coupling part

28

coupling part

29

coupling part

30

coupling part

31

coupling device

32

extension

33

extension

34

retaining ring

35

approach

36

sealing surface

37

sealing surface

38

deepening

39

opening

40

Guide extension

41

Guide extension

42

guide web

43

guide web

44

sealing body

45

retaining element

46

coupling part

47

coupling device

48

holding part

49

holder

50

opening

51

cone angle

52

front end

53

diameter

54

front end

55

diameter

56

diameter

57

diameter

58

floor area

59

front

60

distance

61

sealing surface

62

bulkhead

63

opening

64

opening width

65

external dimension

66

groove

67

groove part

68

sealing device

69

sealing element

70

supporting body

71

Side wall

72

recess

73

coating

74

layer

75

layer

76

layer

77

deepening

78

Federation

79

coupling element

80

stop rib

81

central longitudinal axis

82

face

83

face

84

external dimension

85

height

86

distance

87

distance

88

Eckabmessung

89

intersection

90

intersection

91

deformation

92

gap

93

width

94

plenum

95

Separation room.

96

web

97

breakthrough

98

Got over

99

margin

100

margin

101

distance

102

Cross-sectional dimension

103

mounting device

104

Holding projection

105

holding receptacle

106

arrow

107

extension

108

length

109

dimension

110

approach

111

coating

112

extension

113

Strength

114

body

115

approach

116

adhesive layer

Claims (59)

1. Collector device (1), in particular for bodily fluids, pieces of tissue and tissue cultures, having a receiving container (5) and closure mechanisms (8, 9) which can be opened if necessary, and the receiving container (5) has a container wall (12) with an internal and an external surface (15, 16) and the receiving container (5) bounds an interior (10) and has two end regions (6, 7) with an open terminal end (22, 59) spaced at a distance apart from one another in the direction of a longitudinal mid-axis (21), and the two end regions (6, 7) are closed off by seals (44) of the closure mechanisms (8, 9), characterised in that the interior (10) . bounded by the internal surface (15) of the-container-wall (12) extends from the first end region (6) to the other end region (7) and the first closure mechanism (8) is provided in the form of a cap (23) covering the terminal end (22) of the receiving container (5) for receiving a cylindrical sealing mechanism (24) pierced therethrough, part of the cylindrical casing of which forms a sealing surface (36), projecting radially outwards beyond which is at least one, preferably continuous, flange-type shoulder (35) which is retained between two projections (32, . 33) of the cap spaced at a distance apart from one another in the direction of the longitudinal mid-axis (21) of the cap (23) and disposed in planes extending perpendicular to this longitudinal mid-axis (21), and which project beyond the cylindrical internal surface of the cap (23) in the direction of the longitudinal mid-axis (21), at least the projection (33) for the terminal end (22) of the receiving container (5) projecting in the direction of the sealing surface (36) being disposed between the flange-type shoulder (35) and the sealing surface (36), and the receiving container (5) has a conical sealing surface in the region of an orifice (50) in the open terminal end (59) of the other end region (7) tapering in the direction towards the interior (10) to form the other closure mechanism (9) and the seal (44) of the other closure mechanism (9) is of a conical design with a terminal end (52) having a larger diameter (53) directed towards a retaining element (45), means being provided between the retaining element (45) and the receiving container (5) for coupling a coupling mechanism (47), and the retaining element (45) is provided with means for retaining the seal (44) in a sealing position in the orifice (50) which tapers towards the interior (10) in an arrangement complementing the seal (44), and the means for coupling the coupling mechanism (47) are disposed on the receiving container (5) in the region of the external surface (16) of the end region (7).
2. Collector device as claimed in claim 1, characterised in that the first closure mechanism (8) has a tubular cap (23) enclosing the terminal end (22) of the cylindrical receiving container (5) and is provided with a sealing mechanism (24) inserted in a terminal end orifice which is connected via a coupling mechanism (31) with the cap (23) and/or the cylindrical receiving container (5), the coupling mechanism (31) consisting of at least two coupling parts (27, 28) spaced at a distance apart from one another in the longitudinal direction and joined to the cap (23) so as to be displaceable therewith, which project beyond a cylindrical internal surface of the cap (23) in the radial direction of the cylindrical receiving container (5) enclosing a receiving region between them, as well as a coupling part (29) of the sealing mechanism (24), formed by a flange-type shoulder (35), inserted in the receiving region to form a retaining ring (34), which, when the coupling part (29) of the sealing mechanism (24) is compressed, is disposed between the former and the side of the coupling part (27) remote from the receiving container (5), in particular a blood sample tube, projecting inwardly beyond the cylindrical receiving orifice of the cap (23) in the direction of the longitudinal mid-axis (21) and a thickness of the flange-type shoulder (35) forming the coupling part (29) of the sealing mechanism (24) in the unassembled state is bigger than a distance between the two coupling parts (27, 28) in the direction of the longitudinal mid-axis (21) less a thickness of the retaining ring (34).
3. Collector device as claimed in claim 1 or 2, characterised in that a wall thickness (13) of the receiving container (5) in the end region (7) incorporating the orifice (50) is thicker than in the other wall regions.
4. Collector device as claimed in one of the preceding claims, characterised in that . the coupling means are arranged on the external circumference (17) of the receiving container (5) in a position overlapping with the orifice (50).
5. Collector device as claimed in one of the preceding claims, characterised in that these coupling means are provided in the form of groove parts (67) distributed in segments around the circumference.
6. Collector device as claimed in one of claims 1 to 4 above, characterised in that . these coupling means are provided in the form of a continuous groove (66).
7. Collector device as claimed in one of claims 1 to 4 above, characterised in that these coupling means are receiving bores, which preferably taper inwards in a conical arrangement, distributed about the circumference.
8. Collector device as claimed in one of claims 1 to 4 above, characterised in that the coupling means are provided in the form of coupling parts projecting out from the external circumference (17) of the receiving container (5).
9. Collector device as claimed in one of the preceding claims, characterised in that a retaining mechanism (103) is provided in an end region (6, 7) of the internal surface (15) of the receiving container (5).
10. Collector device as claimed in claim 9, characterised in that the retaining mechanism (103) is provided in the form of at least one projection (107) projecting out from the internal surface (15) in the direction of the longitudinal mid-axis (21).
11. Collector device as claimed in claim 9 or 10, characterised in that the retaining mechanism (103) is provided in the form of a circumferential projection (107) projecting out from the internal surface (15) in the direction of the longitudinal mid-axis (21).
12. Collector device as claimed in one of claims 9 to 11, characterised in that the retaining mechanism (103) is provided in the form of a coating (111) applied to at least certain regions of the internal surface (15) of the receiving container (5).
13. Collector device as claimed in one of claims 9 to 12, characterised in that the retaining mechanism (103) is provided in the form of a circumferential shoulder (110) in the region of the internal surface (15), formed by a dimensional difference along a length (108) . starting from an open terminal end (22, 59) of the end region (6, 7) in the direction towards the other oppositely lying end region (7, 6), perpendicular to the longitudinal mid-axis (21) between a smaller, internal dimension (14) and another internal dimension (109) bigger than it, and the other bigger dimension (109) is closer to the terminal end (22, 59).
14. Collector device as claimed in one of the preceding claims, characterised in that the seal (44) of the other closure mechanism (9) is a truncated cone.
15. Collector device as claimed in claim 14, characterised in that the largest diameter (53) of the seal (44) is bigger than a largest diameter (56) of the orifice (50) receiving the seal (44).
16. Collector device as claimed in claim 14 or 15, characterised in that a diameter (55) of the seal (44) in the region of a terminal end (54) lying opposite the larger diameter (53) is bigger than a smallest diameter (57) of the orifice (50) receiving the seal (44).
17. Collector device as claimed in one of claims 1, 14 to 16, characterised in that the seal (44) is made from a highly elastic and self-sealing material, in particular a rubber, a pharmaceutical rubber, silicone rubber or bromobutyl rubber.
18. Collector device as claimed in one of claims 1, 14 to 17, characterised in that concave recesses (77) are provided in the region of the terminal ends (52, 54) or end faces of the seal (44) are of a concave design.
19. Collector device as claimed in one of claims 1, 14 to 18, characterised in that the seal (44) is provided as a multi-layered component, made in particular from different materials.
20. Collector device as claimed in one of the preceding claims, characterised in that coupling means are provided on the retaining element (45) in the form of one or more coupling parts (46), such as retaining arms, catch arms or snap-fit arms for example, designed to engage in co-operating recesses or depressions in the receiving container (5).
21. Collector device as claimed in one of the preceding claims, characterised in that the coupling parts (46) or the retaining, catch or snap-fit arms forming them are deformable and elastically reboundable in the radial direction of the retaining element (45).
22. Collector device as claimed in one of the preceding claims, characterised in that one of the coupling parts (46) is provided with an expandable circumferential collar (78) with an inwardly projecting flange-type coupling element (79), at least along a part region of the retaining element (45) in the circumferential direction.
23. Collector device as claimed in one of the preceding claims, characterised in that the retaining element (45) is a cap-type arrangement.
24. Collector device as claimed in one of the preceding claims, characterised in that, when placed in position on the receiving container (5), the coupling parts (46) of the retaining element (45) project out from an external dimension (19) of the receiving container (5) in the direction of the longitudinal mid-axis (21) thereof.
25. Collector device as claimed in one of the preceding claims, characterised in that a maximum external dimension (65) of the retaining element (45) is the same as or slightly bigger than a maximum external cross section (20) or maximum external dimension (19) of the receiving container (5).
26. Collector device as claimed in one of the preceding claims, characterised in that the retaining element (45) or coupling parts (46) thereof is provided with at least one stop rib (80) projecting out from the external circumference (17).
27. Collector device as claimed in one of the preceding claims, characterised in that the seal (44) is fixed to the retaining element (45) or is made as a two-component injection moulding.
28. Collector device as claimed in one of the preceding claims, characterised in that the seal (44) is permanently bonded to the retaining element (45) or is joined thereto by an on-moulding process.
29. Collector device as claimed in one of the preceding claims, characterised in that the seal (44) and the retaining element (45) are made as an integral piece and are preferably made from a highly elastic and self-sealing material, in particular rubber, pharmaceutical rubber, silicone rubber of bromobutyl rubber.
30. Collector device as claimed in one of the preceding claims, characterised in that, if the retaining means of the retaining element (45) project from the outside towards a central middle region of the retaining element (45), they project in a radial direction towards the middle region beyond the largest diameter (53) of the seal (44) when placed in position on the receiving container (5).
31. Collector device as claimed in one of the preceding claims, characterised in that the retaining means are provided in the form of an end wall (62) of the retaining element (45) with an orifice (63) disposed in the middle region.
32. Collector device as claimed in one of the preceding claims, characterised in that a dividing mechanism (11) is provided in the interior (10) of the receiving container (5), in the form of a circumferential sealing mechanism (68) comprising at least one sealing element (69) made from a first material and a support body (70) made from a second material, the seal . mechanism (68) being disposed on the support body (70) and projecting beyond it in the circumferential direction, and the first material for the sealing element (69) is elastically deformable and reboundable.
33. Collector device as claimed in claim 32, characterised in that the sealing element (69) is made from a rubber, silicone rubber, pharmaceutical rubber, bromobutyl rubber, a gel or an elastomeric synthetic material.
34. Collector device as claimed in one of the preceding claims, characterised in that the interior (10) of the receiving container (5) can be evacuated.
35. Collector device as claimed in one of claims 32 to 34, characterised in that, when the receiving container (5) is in the evacuated, non-filled state, the dividing mechanism (11) is close to one of the two closure mechanisms (8, 9), in particular is disposed with its end face (82, 83) lying against the latter.
36. Collector device as claimed in one of claims 32 to 35, characterised in that the surface (15) of the receiving container (5) directed towards the interior (10) is provided with a coating (73) at least between the dividing mechanism (11) and the oppositely lying end region (6, 7).
37. Collector device as claimed in claim 36, characterised in that the coating (73) is formulated so that it detaches from the wall in contact with the media (3, 4) to be collected in the interior (10).
38. Collector device as claimed in one of claims 32 to 37, characterised in that the second material for the support body (70) is of a higher density and/or hardness than the first material for the sealing element (69).
39. Collector device as claimed in one of claims 32 to 38, characterised in that the second material for the support body (70) is a synthetic material, e.g. a thermosetting plastic, optionally containing additives and fillers.
40. Collector device as claimed in one of claims 32 to 39, characterised in that the density of the support body (70) is between 1.03 g/cm³ and 1.06 g/cm³, preferably 1.05 g/cm³.
41. Collector device as claimed in one of claims 32 to 40, characterised in that the material or the second material of the support body (70) is a transparent polystyrene.
42. Collector device as claimed in one of claims 32 to 41, characterised in that the support body (70) is liquid-tight.
43. Collector device as claimed in one of claims 32 to 42, characterised in that the support body (70) has a gas permeability which virtually prevents the passage of gases, at least for a period of 72 hours
44. Collector device as claimed in one of claims 32 to 43, characterised in that the sealing element (69) is fixed to the support body (70) by an on-moulding process.
45. Collector device as claimed in one of claims 32 to 44, characterised in that the . sealing element (69) is an O-ring and/or a sealing lip and/or a thin-walled web or a thin- . walled lamella.
46. Collector device as claimed in one of claims 32 to 45, characterised in that the weight of the support body (70) and/or the dividing mechanism (11) is variable.
47. Collector device as claimed in one of claims 32 to 46, characterised in that the gas permeability of the sealing element (69) is at least the same as or slightly higher than that of the support body (70).
48. Collector device as claimed in one of claims 33 to 47, characterised in that a diagonal corner dimension (88) between a point of intersection (89) of a bottom end face (82) disposed perpendicular to the structural height (85) and a circumferential side wall (71) of the support body (70) and another diametrically opposite point of intersection (90) between the circumferential side wall (71) and the other end face (83) of the support body (70) lying opposite the end face (82) is greater than an internal dimension (14) of the interior (10) of the receiving container (5) receiving the dividing mechanism (11) in an internal cross section (18) disposed perpendicular to the longitudinal mid-axis (21).
49. Collector device as claimed in one of claims 32 to 48, characterised in that a . maximum deformation path (91) of the sealing mechanism (68) in a direction extending perpendicular to the central longitudinal axis (81) of the sealing element (69) in the region projecting beyond the support body (70) is greater than a dimensional difference of the sealing . element (69) in the direction perpendicular to the longitudinal mid-axis (21) in a relaxed non-operating position and in a compressed position inserted in the interior (10) of the receiving container (5).
50. Collector device as claimed in one of claims 32 to 49, characterised in that the specific weight of the second material of the support body (70) is lower than the higher specific weight of the media (3, 4) to be separated by the dividing mechanism (11).
51. Collector device as claimed in one of claims 32 to 50, characterised in that the specific weight of the second material of the support body (70) is higher than the lower specific weight of the media (3, 4) to be separated by the dividing mechanism (11).
52. Collector device as claimed in one of claims 32 to 51, characterised in that the sealing mechanism (68) is made up of several sealing elements (69) disposed on the support body (70) in the structural height (85) thereof and spaced at a distance apart from one another.
53. Collector device as claimed in one of claims 32 to 52, characterised in that at least one sealing element (69) of the sealing mechanism (68) is disposed off-centre from a central longitudinal axis (81) disposed parallel with the structural height (85).
54. Collector device as claimed in one of claims 32 to 53, characterised in that two or more sealing elements (69) of the sealing mechanism (68) are disposed in a complementary arrangement off-centre from a central longitudinal axis (81) of the support body (70).
55. Collector device as claimed in one of claims 32 to 54, characterised in that the centre of gravity of the support body (70) is disposed in the end region assigned to the medium (3, 4) of the mixture (2) having the higher specific weight.
56. Collector device as claimed in one of claims 32 to 55, characterised in that retaining means are provided between the sealing element (69) and the support body (70).
57. Collector device as claimed in one of claims 32 to 56, characterised in that the dividing mechanism (11) is retained in a position, which may be released if necessary, adjoining one of the closure mechanisms (8, 9), by means of a retaining mechanism (103).
58. Collector device as claimed in claim 57, characterised in that the retaining mechanism (103) is provided in the form of at least one retaining projection (104) and/or a retaining seat (105) on the support body (70) in the region of one of the two end faces (82, 83).
59. Collector device as claimed in claim 58, characterised in that the retaining projection (104) is disposed in the region of the central longitudinal axis (81) of the support body (70) and is designed to project out from the end face (82, 83) thereof.

Images