EP0655919A4 - Treatment of human viral infections. - Google Patents

Treatment of human viral infections.

Info

Publication number: EP0655919A4
Authority: EP; European Patent Office
Prior art keywords: treatment; viral infections; human viral; human; infections
Prior art date: 1992-08-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP93920283A

Other languages

German (de)

French (fr)

Other versions

EP0655919A1 (en

Inventor

Arthur B Pardee

Jia-Qiang Li

Clyde Crumpacker

Lin Zhang

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Dana Farber Cancer Institute Inc

Beth Israel Deaconess Medical Center Inc

Original Assignee

Dana Farber Cancer Institute Inc

Beth Israel Hospital Association

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-08-21

Filing date

1993-08-23

Publication date

1995-10-18

1993-08-23 Application filed by Dana Farber Cancer Institute Inc, Beth Israel Hospital Association filed Critical Dana Farber Cancer Institute Inc

1995-06-07 Publication of EP0655919A1 publication Critical patent/EP0655919A1/en

1995-10-18 Publication of EP0655919A4 publication Critical patent/EP0655919A4/en

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP93920283A 1992-08-21 1993-08-23 Treatment of human viral infections. Withdrawn EP0655919A4 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US933460		1978-08-14
US93346092A	1992-08-21	1992-08-21
US632093A	1993-01-19	1993-01-19
US6320		1993-01-19
PCT/US1993/007934 WO1994004160A1 (en)	1992-08-21	1993-08-23	Treatment of human viral infections

Publications (2)

Publication Number	Publication Date
EP0655919A1 EP0655919A1 (en)	1995-06-07
EP0655919A4 true EP0655919A4 (en)	1995-10-18

Family

ID=26675474

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP93920283A Withdrawn EP0655919A4 (en)	1992-08-21	1993-08-23	Treatment of human viral infections.

Country Status (4)

Country	Link
EP (1)	EP0655919A4 (en)
JP (1)	JPH08502044A (en)
CA (1)	CA2142831A1 (en)
WO (1)	WO1994004160A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5491237A (en) *	1994-05-03	1996-02-13	Glaxo Wellcome Inc.	Intermediates in pharmaceutical camptothecin preparation
WO1997032587A1 (en) *	1996-03-04	1997-09-12	Dana-Farber Cancer Institute	Methods for treating viral infections
US6395541B1 (en)	1996-05-23	2002-05-28	The Rockefeller University	Methods for the identification of compounds capable of inhibiting HIV-1 viral replication employing murine cell lines expressing human topoisomerase I
US6559309B2 (en)	1996-11-01	2003-05-06	Osi Pharmaceuticals, Inc.	Preparation of a camptothecin derivative by intramolecular cyclisation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0220601A1 (en) *	1985-10-21	1987-05-06	Daiichi Seiyaku Co., Ltd.	Pyranoindolizine derivatives and preparation process thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5004758A (en) *	1987-12-01	1991-04-02	Smithkline Beecham Corporation	Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells
US5422344A (en) *	1990-05-08	1995-06-06	The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services	Method of treating retroviral infections in mammals

1993
- 1993-08-23 JP JP6506587A patent/JPH08502044A/en active Pending
- 1993-08-23 EP EP93920283A patent/EP0655919A4/en not_active Withdrawn
- 1993-08-23 WO PCT/US1993/007934 patent/WO1994004160A1/en not_active Application Discontinuation
- 1993-08-23 CA CA002142831A patent/CA2142831A1/en not_active Abandoned

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0220601A1 (en) *	1985-10-21	1987-05-06	Daiichi Seiyaku Co., Ltd.	Pyranoindolizine derivatives and preparation process thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CRUMPACKER C ET AL: "TOPOTECAN A TOPOISOMERASE I INHIBITOR INHIBITS HIV-1 REPLICATION IN ACUTELY AND CHRONICALLY INFECTED CELLS", IXTH INTERNATIONAL CONFERENCE ON AIDS AND THE IVTH STD WORLD CONGRESS. MEETING, BERLIN, GERMANY, JUNE 6-11, 1993.; PAGE 33. *
E. PRIEL ET AL.: "Inhibition of Human Immunodeficiency Virus (HIV-1) replication in vitro by noncytotoxic doses of camptothecin, a topoisomerase I inhibitor", AIDS RES. HUM. RETROVIRUSES, vol. 7, no. 1, 1991, pages 65 - 72 *
LI CJ ET AL: "Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication.", PROC NATL ACAD SCI U S A (UNITED STATES), MAR 1 1993, VOL. 90, NO. 5, PAGE(S) 1839-42, *
See also references of WO9404160A1 *

Also Published As

Publication number	Publication date
CA2142831A1 (en)	1994-03-03
JPH08502044A (en)	1996-03-05
WO1994004160A1 (en)	1994-03-03
EP0655919A1 (en)	1995-06-07

Publication	Publication Date	Title
EP0831873A4 (en)	2002-07-17	The treatment of hiv and other viral infections using combinatory therapy
IL129352A0 (en)	2000-02-17	Benzimidazole-2- carbamates for the treatment of viral infections and cancer
EP0559791A4 (en)	1993-10-20	Treatment of topical infections
GB9226683D0 (en)	1993-02-17	Skin treatment system
GB9304746D0 (en)	1993-04-28	Treatment of viral infections
EP0610444A4 (en)	1995-05-17	Method of treating viral diseases.
GB9222260D0 (en)	1992-12-09	Skin treatment
ZA931063B (en)	1993-09-23	Treatment of glaucoma.
AU3530395A (en)	1996-04-19	Treatment of viral infections
EP0655919A4 (en)	1995-10-18	Treatment of human viral infections.
PL317876A1 (en)	1997-04-28	Combined treatment of hiv infections
AU8185491A (en)	1992-01-07	Treatment of disease
GB9226958D0 (en)	1993-02-17	Produktionsaktieselskab) novel treatment
GB9217124D0 (en)	1992-09-23	Medical treatment
IL101749A0 (en)	1992-12-30	Treatment of mastitis
ZA941471B (en)	1994-09-27	Treatment of viral infections
GB9216360D0 (en)	1992-09-16	Treatment of blood
GB9422923D0 (en)	1995-01-04	Treatment of viral infections
ZA971041B (en)	1998-11-06	Treatment of viral infections
GB9218773D0 (en)	1992-10-21	Skin treatment
AU5960894A (en)	1994-07-19	Treatment of viral infections
BG52099B2 (en)	1996-12-31	Gel for the treatment of skin viral infections
IE880770L (en)	1988-09-17	Treatment of viral infections
IE892991L (en)	1990-03-20	Treatment of viral infections
GB9204062D0 (en)	1992-04-08	Medical treatment

Legal Events

Date	Code	Title	Description
1995-04-21	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1995-06-07	17P	Request for examination filed	Effective date: 19950321
1995-06-07	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1995-10-18	A4	Supplementary search report drawn up and despatched	Effective date: 19950830
1995-10-18	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1997-11-28	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN
1998-01-14	18W	Application withdrawn	Withdrawal date: 19971117