EP0466780A4 - Megakaryocyte growth promoting activity - Google Patents
Megakaryocyte growth promoting activityInfo
- Publication number
- EP0466780A4 EP0466780A4 EP19900906033 EP90906033A EP0466780A4 EP 0466780 A4 EP0466780 A4 EP 0466780A4 EP 19900906033 EP19900906033 EP 19900906033 EP 90906033 A EP90906033 A EP 90906033A EP 0466780 A4 EP0466780 A4 EP 0466780A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- growth promoting
- promoting activity
- megakaryocyte growth
- megakaryocyte
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Fodder In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33265189A | 1989-04-03 | 1989-04-03 | |
US332651 | 1989-04-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0466780A1 EP0466780A1 (en) | 1992-01-22 |
EP0466780A4 true EP0466780A4 (en) | 1992-08-26 |
Family
ID=23299216
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19900906033 Withdrawn EP0466780A4 (en) | 1989-04-03 | 1990-04-02 | Megakaryocyte growth promoting activity |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0466780A4 (en) |
JP (1) | JPH04506513A (en) |
AU (1) | AU641645B2 (en) |
CA (1) | CA2050584A1 (en) |
WO (1) | WO1990012108A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6433142B1 (en) * | 1989-08-08 | 2002-08-13 | Genetics Institute, Llc | Megakaryocyte stimulating factors |
WO1992006712A1 (en) * | 1990-10-12 | 1992-04-30 | Amgen Inc. | Megakaryocyte maturation factors |
CA2108580A1 (en) * | 1991-05-31 | 1992-12-01 | Arthur J. Ammann | Treatment of hiv-associated immune thrombocytopenic purpura |
WO1993000433A1 (en) * | 1991-06-28 | 1993-01-07 | New England Deaconess Hospital | A differentiated megakaryocyte line producing novel megakaryocyte differentiation factors |
US5250732A (en) * | 1991-07-18 | 1993-10-05 | Genentech, Inc. | Ketamine analogues for treatment of thrombocytopenia |
CN1107891A (en) * | 1994-03-04 | 1995-09-06 | 上海贝特生物技术有限公司 | Human megacaryocyte auxin and its separating purification and gene clone method and application |
US5795569A (en) * | 1994-03-31 | 1998-08-18 | Amgen Inc. | Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation |
EP0755263A4 (en) * | 1994-03-31 | 2005-02-09 | Amgen Inc | Compositions and methods for stimulating megakaryocyte growth and differentiation |
TW497972B (en) * | 1995-06-08 | 2002-08-11 | Kirin Brewery | Stable thrombopoietin (TPO)-containing lyophilized compositions |
RU2482870C1 (en) * | 2012-02-27 | 2013-05-27 | Федеральное государственное бюджетное учреждение "Российский онкологический научный центр имени Н.Н. Блохина" Российской академии медицинских наук (ФГБУ "РОНЦ им. Н.Н. Блохина" РАМН) | Agent inducing hemopoietic stem cell differentiation into thrombocytes |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991002001A1 (en) * | 1989-08-08 | 1991-02-21 | Genetics Institute, Inc. | A megakaryocytopoietic factor |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4695542A (en) * | 1983-10-04 | 1987-09-22 | Dnax Research Institute Of Molecular And Cellular Biology, Inc. | cDNA clones coding for polypeptides exhibiting multi-lineage cellular growth factor activity |
-
1990
- 1990-04-02 EP EP19900906033 patent/EP0466780A4/en not_active Withdrawn
- 1990-04-02 WO PCT/US1990/001725 patent/WO1990012108A1/en not_active Application Discontinuation
- 1990-04-02 AU AU54058/90A patent/AU641645B2/en not_active Ceased
- 1990-04-02 JP JP2505718A patent/JPH04506513A/en active Pending
- 1990-04-02 CA CA002050584A patent/CA2050584A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991002001A1 (en) * | 1989-08-08 | 1991-02-21 | Genetics Institute, Inc. | A megakaryocytopoietic factor |
Non-Patent Citations (5)
Title |
---|
EXPERIMENTAL HEMATOLOGY vol. 13, no. 11, December 1985, NEW YORK, USA pages 1164 - 1172; MAZUR, E.M. ET AL.: 'Human megakaryocyte colony stimulating factor in sera from aplastic dogs : partial purification, characterization and determination of hematopoietic cell lineage specificty.' * |
EXPERIMENTAL HEMATOLOGY vol. 14, no. 6, 1986, NEW YORK, USA page 490; SHIMIZU, T. ET AL.: 'Purification of human megakaryocyte colony stimulating factor.' * |
EXPERIMENTAL HEMATOLOGY vol. 15, no. 5, 1987, NEW YORK, USA page 492; SHIMIZU, T.: 'Purification of human sialylated megakaryocyte colony stimulating factor.' * |
See also references of WO9012108A1 * |
THE JOURNAL OF CLINICAL INVESTIGATION vol. 75, no. 4, April 1985, THE AMERICAN SOCIETY FOR CLIN. INV. pages 1174 - 1182; HOFFMAN, R. ET AL.: 'Purification and partial characterization of a megakaryocyte colony-stimulating factor from human plasma.' * |
Also Published As
Publication number | Publication date |
---|---|
CA2050584A1 (en) | 1990-10-04 |
WO1990012108A1 (en) | 1990-10-18 |
AU641645B2 (en) | 1993-09-30 |
EP0466780A1 (en) | 1992-01-22 |
AU5405890A (en) | 1990-11-05 |
JPH04506513A (en) | 1992-11-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19911001 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19920707 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE |
|
17Q | First examination report despatched |
Effective date: 19940415 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19940826 |