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EG20543A - Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones - Google Patents

Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones

Info

Publication number
EG20543A
EG20543A EG68693A EG68693A EG20543A EG 20543 A EG20543 A EG 20543A EG 68693 A EG68693 A EG 68693A EG 68693 A EG68693 A EG 68693A EG 20543 A EG20543 A EG 20543A
Authority
EG
Egypt
Prior art keywords
quinolones
preparing
novel antimicrobial
heterosubstituted amino
heterosubstituted
Prior art date
Application number
EG68693A
Inventor
Thomas Prosser Demuth Jr
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Application granted granted Critical
Publication of EG20543A publication Critical patent/EG20543A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
EG68693A 1992-10-30 1993-01-30 Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones EG20543A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96896092A 1992-10-30 1992-10-30

Publications (1)

Publication Number Publication Date
EG20543A true EG20543A (en) 1999-07-31

Family

ID=25514997

Family Applications (1)

Application Number Title Priority Date Filing Date
EG68693A EG20543A (en) 1992-10-30 1993-01-30 Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones

Country Status (21)

Country Link
EP (1) EP0666853A1 (en)
JP (1) JPH08502750A (en)
KR (1) KR950704301A (en)
CN (1) CN1064357C (en)
AU (1) AU687018B2 (en)
BR (1) BR9307347A (en)
CA (1) CA2148003A1 (en)
CZ (1) CZ282581B6 (en)
EG (1) EG20543A (en)
FI (1) FI952049A0 (en)
HU (1) HUT72072A (en)
IL (1) IL107323A (en)
MX (1) MX9306814A (en)
NO (1) NO951640L (en)
NZ (1) NZ257470A (en)
PL (1) PL178094B1 (en)
RU (1) RU2126000C1 (en)
SG (1) SG59979A1 (en)
SK (1) SK54795A3 (en)
WO (1) WO1994010163A1 (en)
ZA (1) ZA938089B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
MX9700871A (en) * 1994-08-02 1997-05-31 Procter & Gamble Process for making antimicrobial compounds.
AU3154095A (en) * 1994-08-02 1996-03-04 Procter & Gamble Company, The Process for making quinolonyl lactam antimicrobials and novel intermediate compounds
CA2242242C (en) * 1996-02-09 2001-08-07 Toyama Chemical Co., Ltd. Quinolonecarboxylic acid derivatives or salts thereof
US8524735B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
KR101488402B1 (en) * 2005-05-18 2015-02-03 엠펙스 파마슈티컬즈, 인코포레이티드 Aerosolized fluoroquinolones and uses thereof
EE05697B1 (en) 2005-06-08 2014-02-17 Janssen Pharmaceutica N.V. Quinoline derivatives as antibacterial agents
EA010601B1 (en) * 2005-06-09 2008-10-30 Янссен Фармацевтика Н.В. Quinoline derivatives as antibacterial agents
CN101020647B (en) * 2007-02-14 2011-03-30 杭州师范学院 Synthesis process of beta-cyclopropylamino acrylate
EP2150544B1 (en) * 2007-03-19 2016-01-13 Takeda Pharmaceutical Company Limited Mapk/erk kinase inhibitors
JP5824213B2 (en) * 2007-10-05 2015-11-25 センワ バイオサイエンシズ インコーポレイテッド Quinolone analogs and related methods
TWI441830B (en) * 2008-06-03 2014-06-21 Actelion Pharmaceuticals Ltd [4-(1-amino-ethyl)-cyclohexyl]-methyl-amine and [6-(1-amino-ethyl)-tetrahydro-pyran-3-yl]-methyl-ami ne derivatives
ES2809177T3 (en) 2008-10-07 2021-03-03 Horizon Orphan Llc Inhalation of levofloxacin to reduce lung inflammation
KR20110091510A (en) 2008-10-07 2011-08-11 엠펙스 파마슈티컬즈, 인코포레이티드 Aerosol fluoroquinolone formulations for improved pharmacokinetics
AR076222A1 (en) * 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd DERIVATIVES 2-HYDROXIETIL-1H-QUINOLIN-ONA AND ITS AZAISOTHERAL ANALOGS WITH ANTIBACTERIAL ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CA2938650C (en) 2009-09-04 2018-01-09 Raptor Pharmaceuticals Inc. Use of aerosolized levofloxacin for treating cystic fibrosis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
JPH0228178A (en) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd Novel pyridonecarboxylic acid derivative and salt thereof
DE3906365A1 (en) * 1988-07-15 1990-01-18 Bayer Ag 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM
HU219403B (en) * 1989-08-16 2001-04-28 Pfizer Inc. Azabicyclo-substituted quinolone and naphthyridone carboxylic acids and process for producing them
AU640481B2 (en) * 1990-04-18 1993-08-26 Norwich Eaton Pharmaceuticals, Inc. Penicillan or cephalosporin derivatives of quinolonyl
JPH06503565A (en) * 1990-11-30 1994-04-21 ワーナー−ランバート・コンパニー Individual stereoisomers of 7-[3-(aminoalkyl)-1-pyrrolidinyl]-quinolone and naphthyridone as antibacterial agents

Also Published As

Publication number Publication date
IL107323A (en) 2000-06-01
PL178094B1 (en) 2000-02-29
NO951640D0 (en) 1995-04-28
SG59979A1 (en) 1999-02-22
HU9501237D0 (en) 1995-06-28
CZ109795A3 (en) 1995-12-13
IL107323A0 (en) 1994-01-25
MX9306814A (en) 1994-07-29
SK54795A3 (en) 1995-12-06
JPH08502750A (en) 1996-03-26
AU5409794A (en) 1994-05-24
CZ282581B6 (en) 1997-08-13
FI952049A (en) 1995-04-28
CN1092773A (en) 1994-09-28
RU95110762A (en) 1997-01-10
BR9307347A (en) 1999-05-25
KR950704301A (en) 1995-11-17
CA2148003A1 (en) 1994-05-11
NO951640L (en) 1995-06-30
FI952049A0 (en) 1995-04-28
AU687018B2 (en) 1998-02-19
CN1064357C (en) 2001-04-11
NZ257470A (en) 1997-08-22
PL308671A1 (en) 1995-08-21
RU2126000C1 (en) 1999-02-10
HUT72072A (en) 1996-03-28
WO1994010163A1 (en) 1994-05-11
EP0666853A1 (en) 1995-08-16
ZA938089B (en) 1994-06-07

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