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EE200600044A - Antisens-oligonukleotiid ja selle kasutamine perifeerse neuronaalse l„mmastikoksiidi sntaasi allareguleerimiseks ning farmatseutiline kompositsioon - Google Patents

Antisens-oligonukleotiid ja selle kasutamine perifeerse neuronaalse l„mmastikoksiidi sntaasi allareguleerimiseks ning farmatseutiline kompositsioon

Info

Publication number
EE200600044A
EE200600044A EEP200600044A EEP200600044A EE200600044A EE 200600044 A EE200600044 A EE 200600044A EE P200600044 A EEP200600044 A EE P200600044A EE P200600044 A EEP200600044 A EE P200600044A EE 200600044 A EE200600044 A EE 200600044A
Authority
EE
Estonia
Prior art keywords
sase
regulation
pharmaceutical composition
nitric oxide
antisense oligonucleotide
Prior art date
Application number
EEP200600044A
Other languages
English (en)
Inventor
Kolesnikov Yuri
Original Assignee
Tartu Ülikool
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tartu Ülikool filed Critical Tartu Ülikool
Priority to EEP200600044A priority Critical patent/EE200600044A/et
Priority to PCT/EE2007/000026 priority patent/WO2008080413A2/en
Publication of EE200600044A publication Critical patent/EE200600044A/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111General methods applicable to biologically active non-coding nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications
    • C12N2320/32Special delivery means, e.g. tissue-specific

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EEP200600044A 2006-12-29 2006-12-29 Antisens-oligonukleotiid ja selle kasutamine perifeerse neuronaalse l„mmastikoksiidi sntaasi allareguleerimiseks ning farmatseutiline kompositsioon EE200600044A (et)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EEP200600044A EE200600044A (et) 2006-12-29 2006-12-29 Antisens-oligonukleotiid ja selle kasutamine perifeerse neuronaalse l„mmastikoksiidi sntaasi allareguleerimiseks ning farmatseutiline kompositsioon
PCT/EE2007/000026 WO2008080413A2 (en) 2006-12-29 2007-12-21 An antisense oligonucleotide, pharmaceutical composition and a method for downregulation of peripheral neuronal nitric oxide synthase and mu-opioid receptors and use of an antisense oligonucleotide for drug production

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EEP200600044A EE200600044A (et) 2006-12-29 2006-12-29 Antisens-oligonukleotiid ja selle kasutamine perifeerse neuronaalse l„mmastikoksiidi sntaasi allareguleerimiseks ning farmatseutiline kompositsioon

Publications (1)

Publication Number Publication Date
EE200600044A true EE200600044A (et) 2008-12-15

Family

ID=39199385

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200600044A EE200600044A (et) 2006-12-29 2006-12-29 Antisens-oligonukleotiid ja selle kasutamine perifeerse neuronaalse l„mmastikoksiidi sntaasi allareguleerimiseks ning farmatseutiline kompositsioon

Country Status (2)

Country Link
EE (1) EE200600044A (et)
WO (1) WO2008080413A2 (et)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001087285A2 (en) * 2000-05-12 2001-11-22 The Johns Hopkins University Inhibition of the interaction of psd93 and psd95 with the nnos and nmda receptors
ES2696598T3 (es) * 2005-03-21 2019-01-17 Univ Columbia Compuestos de balanol para su uso en el tratamiento de dolor

Also Published As

Publication number Publication date
WO2008080413A3 (en) 2008-09-12
WO2008080413A2 (en) 2008-07-10

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