EE04157B1 - Sünteetilised polüsahhariidid, nende valmistamismeetodid ja neid sisaldavad farmatseutilised kompositsioonid - Google Patents

Sünteetilised polüsahhariidid, nende valmistamismeetodid ja neid sisaldavad farmatseutilised kompositsioonid

Info

Publication number: EE04157B1
Authority: EE; Estonia
Prior art keywords: processes; preparation; pharmaceutical compositions; compositions containing; synthetic polysaccharides
Prior art date: 1998-01-19

Application number

EEP200000429A

Other languages

English (en)

Estonian (et)

Inventor

Egbertus Maria Basten Johannes

Dreef-Tromp Cornelia

Driguez Pierre-Alexandre

Duchaussoy Philippe

Petitou Maurice

Adriaan Anton Van Boeckel Constant

Herbert Jean-Marc

Original Assignee

Sanofi-Synthlabo

Akzo Nobel N.V.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-19

Filing date

1999-01-13

Publication date

2003-10-15

1999-01-13 Application filed by Sanofi-Synthlabo, Akzo Nobel N.V. filed Critical Sanofi-Synthlabo

2001-12-17 Publication of EE200000429A publication Critical patent/EE200000429A/xx

2003-06-16 Publication of EE200000429A1 publication Critical patent/EE200000429A1/xx

2003-10-15 Publication of EE04157B1 publication Critical patent/EE04157B1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Materials Engineering (AREA)
Hematology (AREA)
Diabetes (AREA)
Polymers & Plastics (AREA)
Biochemistry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Medicinal Preparation (AREA)

EEP200000429A 1998-01-19 1999-01-13 Sünteetilised polüsahhariidid, nende valmistamismeetodid ja neid sisaldavad farmatseutilised kompositsioonid EE04157B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9800515A FR2773804B1 (fr)	1998-01-19	1998-01-19	Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant
PCT/FR1999/000044 WO1999036443A1 (fr)	1998-01-19	1999-01-13	Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant

Publications (3)

Publication Number	Publication Date
EE200000429A EE200000429A (et)	2001-12-17
EE200000429A1 EE200000429A1 (et)	2003-06-16
EE04157B1 true EE04157B1 (et)	2003-10-15

Family

ID=9521914

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200000429A EE04157B1 (et)	1998-01-19	1999-01-13	Sünteetilised polüsahhariidid, nende valmistamismeetodid ja neid sisaldavad farmatseutilised kompositsioonid

Country Status (41)

Country	Link
US (1)	US6528497B1 (xx)
EP (1)	EP1049721B1 (xx)
JP (1)	JP4402835B2 (xx)
KR (1)	KR100513196B1 (xx)
CN (1)	CN1165550C (xx)
AR (1)	AR013019A1 (xx)
AT (1)	ATE209219T1 (xx)
AU (1)	AU741748B2 (xx)
BR (1)	BRPI9907025B8 (xx)
CA (1)	CA2317465C (xx)
CO (1)	CO4970795A1 (xx)
CZ (1)	CZ297815B6 (xx)
DE (1)	DE69900718T2 (xx)
DK (1)	DK1049721T3 (xx)
DZ (1)	DZ2709A1 (xx)
EE (1)	EE04157B1 (xx)
EG (1)	EG23982A (xx)
ES (1)	ES2168000T3 (xx)
FR (1)	FR2773804B1 (xx)
GT (1)	GT199900003A (xx)
HK (1)	HK1030002A1 (xx)
HR (1)	HRP20000480B1 (xx)
HU (1)	HU228333B1 (xx)
IL (1)	IL137241A0 (xx)
MA (1)	MA26597A1 (xx)
MY (1)	MY119090A (xx)
NO (1)	NO329903B1 (xx)
NZ (1)	NZ505492A (xx)
PE (1)	PE20000269A1 (xx)
PL (1)	PL202802B1 (xx)
PT (1)	PT1049721E (xx)
RU (1)	RU2211224C2 (xx)
SA (1)	SA99191113B1 (xx)
SI (1)	SI1049721T1 (xx)
SK (1)	SK283411B6 (xx)
TR (1)	TR200002078T2 (xx)
TW (1)	TW548279B (xx)
UA (1)	UA60352C2 (xx)
UY (1)	UY25356A1 (xx)
WO (1)	WO1999036443A1 (xx)
ZA (1)	ZA99355B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2814463B1 (fr)	2000-09-22	2002-11-15	Sanofi Synthelabo	Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
FR2874924B1 (fr) *	2004-09-09	2006-12-01	Sanofi Aventis Sa	Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh)	2004-12-23	2013-08-01	Merck Sharp & Dohme	包含生物素殘基之抗血栓雙重抑制劑
GB0507577D0 (en)	2005-04-14	2005-05-18	Novartis Ag	Organic compounds
IL188647A0 (en) *	2008-01-08	2008-11-03	Orina Gribova	Adaptable structured drug and supplements administration system (for oral and/or transdermal applications)
US8791064B2 (en) *	2008-04-24	2014-07-29	Technion Research And Development Foundation Ltd.	Beta-lactoglobulin-polysaccharide nanoparticles for hydrophobic bioactive compounds
CN102046781A (zh)	2008-05-30	2011-05-04	动量制药公司	糖结构以及制造和使用此类结构的方法
FR2935386B1 (fr) *	2008-08-26	2010-09-10	Sanofi Aventis	Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine
CA2757091A1 (en) *	2009-03-30	2010-10-14	University Of Georgia Research Foundation, Inc.	Heparan sulfate synthesis
AU2010269815B2 (en)	2009-07-09	2015-10-15	Oshadi Drug Administration Ltd.	Matrix carrier compositions, methods and uses
CN104245718B (zh)	2009-07-31	2016-11-09	可靠生物医药公司	制备磺达肝素钠的方法及其合成中使用的中间体
FR2949115B1 (fr)	2009-08-14	2012-11-02	Sanofi Aventis	OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2949114B1 (fr)	2009-08-14	2011-08-26	Sanofi Aventis	OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
US8420790B2 (en)	2009-10-30	2013-04-16	Reliable Biopharmaceutical Corporation	Efficient and scalable process for the manufacture of Fondaparinux sodium
EP2614089A1 (fr)	2010-09-10	2013-07-17	Sanofi-Aventis	Polysaccharides biotinyles a activite antithrombotique et presentant une stabilite metabolique amelioree
US9005664B2 (en)	2010-10-17	2015-04-14	Technion Research And Development Foundation Ltd.	Denatured lactoglobulin and polyphenol coassemblies
FR2970969B1 (fr)	2011-01-27	2013-10-18	Sanofi Aventis	Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ260933A (en) *	1993-07-16	1996-07-26	Hercules Inc	Cation-complexed polysaccharides; use in foods and pharmaceuticals
FR2749849B1 (fr) *	1996-06-14	1998-09-04	Sanofi Sa	Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
CZ427499A3 (cs) *	1998-05-29	2000-05-17	The Procter & Gamble Company	Jemné topické antimikrobiální přípravky

1998
- 1998-01-19 FR FR9800515A patent/FR2773804B1/fr not_active Expired - Lifetime
1999
- 1999-01-13 JP JP2000540158A patent/JP4402835B2/ja not_active Expired - Fee Related
- 1999-01-13 TR TR2000/02078T patent/TR200002078T2/xx unknown
- 1999-01-13 EE EEP200000429A patent/EE04157B1/xx unknown
- 1999-01-13 UA UA2000074011A patent/UA60352C2/uk unknown
- 1999-01-13 CA CA002317465A patent/CA2317465C/en not_active Expired - Fee Related
- 1999-01-13 BR BRPI9907025A patent/BRPI9907025B8/pt not_active IP Right Cessation
- 1999-01-13 NZ NZ505492A patent/NZ505492A/en not_active IP Right Cessation
- 1999-01-13 DK DK99900524T patent/DK1049721T3/da active
- 1999-01-13 AU AU19745/99A patent/AU741748B2/en not_active Ceased
- 1999-01-13 PL PL341875A patent/PL202802B1/pl unknown
- 1999-01-13 KR KR10-2000-7007824A patent/KR100513196B1/ko not_active IP Right Cessation
- 1999-01-13 DE DE69900718T patent/DE69900718T2/de not_active Expired - Lifetime
- 1999-01-13 CN CNB998022438A patent/CN1165550C/zh not_active Expired - Fee Related
- 1999-01-13 WO PCT/FR1999/000044 patent/WO1999036443A1/fr active IP Right Grant
- 1999-01-13 ES ES99900524T patent/ES2168000T3/es not_active Expired - Lifetime
- 1999-01-13 RU RU2000119753/04A patent/RU2211224C2/ru not_active IP Right Cessation
- 1999-01-13 SI SI9930025T patent/SI1049721T1/xx unknown
- 1999-01-13 PT PT99900524T patent/PT1049721E/pt unknown
- 1999-01-13 SK SK1078-2000A patent/SK283411B6/sk not_active IP Right Cessation
- 1999-01-13 EP EP99900524A patent/EP1049721B1/fr not_active Expired - Lifetime
- 1999-01-13 IL IL13724199A patent/IL137241A0/xx not_active IP Right Cessation
- 1999-01-13 AT AT99900524T patent/ATE209219T1/de active
- 1999-01-13 HU HU0102009A patent/HU228333B1/hu not_active IP Right Cessation
- 1999-01-13 CZ CZ20002635A patent/CZ297815B6/cs not_active IP Right Cessation
- 1999-01-13 US US09/600,506 patent/US6528497B1/en not_active Expired - Lifetime
- 1999-01-14 GT GT199900003A patent/GT199900003A/es unknown
- 1999-01-15 MA MA25431A patent/MA26597A1/fr unknown
- 1999-01-16 EG EG5499A patent/EG23982A/xx active
- 1999-01-16 DZ DZ990010A patent/DZ2709A1/xx active
- 1999-01-18 UY UY25356A patent/UY25356A1/es not_active Application Discontinuation
- 1999-01-18 AR ARP990100172A patent/AR013019A1/es active IP Right Grant
- 1999-01-18 TW TW088100716A patent/TW548279B/zh not_active IP Right Cessation
- 1999-01-18 MY MYPI99000203A patent/MY119090A/en unknown
- 1999-01-19 ZA ZA9900355A patent/ZA99355B/xx unknown
- 1999-01-19 PE PE1999000044A patent/PE20000269A1/es not_active Application Discontinuation
- 1999-01-19 CO CO99002526A patent/CO4970795A1/es unknown
- 1999-02-27 SA SA99191113A patent/SA99191113B1/ar unknown
2000
- 2000-07-17 NO NO20003662A patent/NO329903B1/no not_active IP Right Cessation
- 2000-07-19 HR HR970630A patent/HRP20000480B1/xx not_active IP Right Cessation
2001
- 2001-02-12 HK HK01101003A patent/HK1030002A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR20010034189A (ko)	2001-04-25
TR200002078T2 (tr)	2000-11-21
NO20003662D0 (no)	2000-07-17
DZ2709A1 (fr)	2003-09-01
EE200000429A (et)	2001-12-17
ES2168000T3 (es)	2002-05-16
HUP0102009A1 (hu)	2001-11-28
HUP0102009A3 (en)	2003-07-28
EP1049721A1 (fr)	2000-11-08
PE20000269A1 (es)	2000-06-15
EG23982A (en)	2008-02-27
DK1049721T3 (da)	2002-04-02
CA2317465C (en)	2008-05-20
AR013019A1 (es)	2000-11-22
SK283411B6 (sk)	2003-07-01
MY119090A (en)	2005-03-31
BR9907025A (pt)	2000-10-17
PL202802B1 (pl)	2009-07-31
IL137241A0 (en)	2001-07-24
NO20003662L (no)	2000-09-14
ATE209219T1 (de)	2001-12-15
UY25356A1 (es)	2000-10-31
BR9907025B1 (pt)	2013-12-10
CN1288470A (zh)	2001-03-21
CN1165550C (zh)	2004-09-08
CZ297815B6 (cs)	2007-04-04
SI1049721T1 (en)	2002-06-30
JP4402835B2 (ja)	2010-01-20
EP1049721B1 (fr)	2001-11-21
DE69900718D1 (de)	2002-02-21
FR2773804A1 (fr)	1999-07-23
NO329903B1 (no)	2011-01-24
HRP20000480A2 (en)	2000-12-31
KR100513196B1 (ko)	2005-09-07
PL341875A1 (en)	2001-05-07
GT199900003A (es)	2000-07-07
UA60352C2 (uk)	2003-10-15
RU2211224C2 (ru)	2003-08-27
SK10782000A3 (sk)	2001-02-12
CA2317465A1 (en)	1999-07-22
MA26597A1 (fr)	2004-12-20
HRP20000480B1 (en)	2002-04-30
SA99191113B1 (ar)	2006-10-11
DE69900718T2 (de)	2002-08-22
HK1030002A1 (en)	2001-04-20
JP2002509164A (ja)	2002-03-26
WO1999036443A1 (fr)	1999-07-22
CZ20002635A3 (cs)	2000-12-13
EE200000429A1 (et)	2003-06-16
CO4970795A1 (es)	2000-11-07
TW548279B (en)	2003-08-21
PT1049721E (pt)	2002-05-31
BRPI9907025B8 (pt)	2016-09-13
AU1974599A (en)	1999-08-02
NZ505492A (en)	2001-12-21
US6528497B1 (en)	2003-03-04
HU228333B1 (en)	2013-03-28
ZA99355B (en)	2000-10-11
FR2773804B1 (fr)	2000-02-18
AU741748B2 (en)	2001-12-06

Publication	Publication Date	Title
EE200000168A (et)	2001-04-16	Karboksamidotiasoolderivaadid, nende valmistamine ja neid sisaldavad farmatseutilised kompositsioonid
EE200000791A (et)	2002-02-15	Uudsed atsüülpseudopeptiidid, nende valmistamise meetod ja neid sisaldavad farmatseutilised kompositsioonid
EE200200138A (et)	2003-06-16	Kinolüülpropüülpiperidiini derivaadid, nende valmistamine ja neid sisaldavad kompositsioonid
EE200000707A (et)	2002-04-15	Oksasolidinooni derivaadid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid
EE04673B1 (et)	2006-08-15	Kinoliini derivaadid, nende valmistamine ja kasutamine ravimina ning neid sisaldavad farmatseutilised kompositsioonid
EE03929B1 (et)	2002-12-16	Sünteetilised polüsahhariidid, nende valmistamisemeetod ja neid sisaldavad farmatseutilised kompositsioonid
EE200200409A (et)	2003-12-15	1,3-dihüdro-2H-indool-2-ooni derivaadid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid
EE9500064A (et)	1996-06-17	Asendatud 1H-imidasoolid, nende valmistamismeetodid ja farmatseutilised kompositsioonid
EE9800028A (et)	1998-08-17	Iprotroopiumsoolad, neid sisaldavad ravimkompositsioonid ja nende kasutamine
EE04498B1 (et)	2005-06-15	Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon
EE200000613A (et)	2002-04-15	Kinoliini derivaadid, nende valmistamismeetodid ja farmatseutilised kompositsioonid
DK1112266T3 (da)	2003-09-15	Substituerede 4-amino-2-arylpyrimidiner, fremstilling og anvendelse deraf og farmaceutiske præparater indeholdende dem
EE04276B1 (et)	2004-04-15	Kinoliini derivaadid, nende valmistamine ja kasutamine ravimina ning neid sisaldavad farmatseutilised kompositsioonid
FI963566A0 (fi)	1996-09-10	Uusia piperatsiinijohdoksia, menetelmiä niiden valmistamiseksi ja niitä sisältäviä koostumuksia
EE9700333A (et)	1998-06-15	Substitueeritud 4-fenüülaminotiasoolid, nende valmistamise meetod ja neid sisaldavad farmakoloogilised kompositsioonid
EE200000429A1 (et)	2003-06-16	Sünteetilised polüsahhariidid, nende valmistamismeetodid ja neid sisaldavad farmatseutilised kompositsioonid
EE9800426A (et)	1999-06-15	Asendatud 2,4-tiasolidiindiooni derivaadid, nende valmistamismeetodid ja neid sisaldavad farmatseutilised kompositsioonid
EE200100027A (et)	2002-06-17	Fosfororgaanilised ühendid, neid sisaldav farmatseutiline preparaat ja nende kasutamine
HK1039122A1 (zh)	2002-04-12	取代的6-苄基-4-氧代嘧啶，其製備方法以及含該化合物的藥物組合物
EE04348B1 (et)	2004-08-16	Sahhariidderivaadid, neid sisaldav farmatseutiline kompositsioon ja nende kasutamine
EE200200022A (et)	2003-04-15	Aminotiasooli derivaadid, nende valmistamine ja neid sisaldavad farmatseutilised kompositsioonid
EE200000421A (et)	2001-12-17	Uued pentasahhariidid, nende valmistamismeetodid ja neid sisaldavad farmatseutilised kompositsioonid
EE03611B1 (et)	2002-02-15	Taksoidid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid
HUP0104834A3 (en)	2005-06-28	Sulphonyloxazolamines, their use, pharmaceutical compositions containing them and their preparation
EE03996B1 (et)	2003-04-15	Farmatseutilised kompositsioonid, nende valmistamismeetod ja kasutamine

Legal Events

Date	Code	Title	Description
2003-06-16	HH1A	Change of representative
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2004-04-15	GB1A	Change in the ownership or in the address of the owner
2005-02-15	HC1A	Change of owner name
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2010-02-15	KB4A	Valid patent at the end of a year	Effective date: 20091231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231