ECSP099411A - Derivados de aril sulfamida y métodos para su uso - Google Patents
Derivados de aril sulfamida y métodos para su usoInfo
- Publication number
- ECSP099411A ECSP099411A EC2009009411A ECSP099411A ECSP099411A EC SP099411 A ECSP099411 A EC SP099411A EC 2009009411 A EC2009009411 A EC 2009009411A EC SP099411 A ECSP099411 A EC SP099411A EC SP099411 A ECSP099411 A EC SP099411A
- Authority
- EC
- Ecuador
- Prior art keywords
- disorders
- derivatives
- methods
- sulfamida
- aril
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/14—Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La presente invención se dirige a derivados de aril sulfamida de la fórmula I; o una sal farmacéuticamente aceptable, estereoisómero o tautómero de estos, que son inhibidores de recaptación de monoamina, composiciones que contienen estos derivados, y métodos para su uso para la prevención y tratamiento de afecciones, que incluyen, inter alia, síntomas vasomotrices, disfunción sexual, trastornos gastrointestinales y trastorno genitourinario, trastornos depresivos, trastornos de comportamiento endogéno, trastornos cognitivos, neuropatía diabética, dolor, y otros enfermedades y trastornos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86964406P | 2006-12-12 | 2006-12-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP099411A true ECSP099411A (es) | 2009-07-31 |
Family
ID=39273293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2009009411A ECSP099411A (es) | 2006-12-12 | 2009-06-12 | Derivados de aril sulfamida y métodos para su uso |
Country Status (20)
Country | Link |
---|---|
US (4) | US7601722B2 (es) |
EP (1) | EP2061776A1 (es) |
JP (1) | JP2010512401A (es) |
KR (1) | KR20090087506A (es) |
CN (1) | CN101600701A (es) |
AR (1) | AR064318A1 (es) |
AU (1) | AU2007333593A1 (es) |
BR (1) | BRPI0720289A2 (es) |
CA (1) | CA2671844A1 (es) |
CL (1) | CL2007003590A1 (es) |
CR (1) | CR10866A (es) |
EC (1) | ECSP099411A (es) |
MX (1) | MX2009006359A (es) |
NO (1) | NO20092092L (es) |
PE (1) | PE20081395A1 (es) |
RU (1) | RU2009121017A (es) |
SV (1) | SV2009003295A (es) |
TW (1) | TW200843753A (es) |
WO (1) | WO2008073459A1 (es) |
ZA (1) | ZA200904109B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090156826A1 (en) * | 2007-12-12 | 2009-06-18 | Wyeth | Methods for the preparation of hydroxy-substituted aryl sulfamide compounds |
GB0813694D0 (en) * | 2008-07-25 | 2008-09-03 | Glaxo Group Ltd | Compounds |
CA2791672A1 (en) * | 2010-03-04 | 2011-09-09 | Merck Sharp & Dohme Corp. | Positive allosteric modulators of mglur2 |
CN102838567B (zh) * | 2011-06-23 | 2014-12-31 | 深圳市湘雅生物医药研究院 | 一种苯磺酰或苯甲酰哌嗪类化合物及其制备方法和用途 |
DK2776387T3 (en) * | 2011-11-07 | 2017-05-08 | Univ Emory | Tricyclic amino containing compounds to treat or prevent symptoms associated with endocrine dysfunction |
US9867813B2 (en) * | 2015-11-17 | 2018-01-16 | Thomas Daly | Aminopyridine based buffers with wide buffering ranges, antibiotics and myelin disease therapy |
CN107337616A (zh) * | 2017-07-13 | 2017-11-10 | 上海昕盛医药科技有限公司 | 一种盐酸班布特罗杂质f的合成方法 |
CN107445845A (zh) * | 2017-08-24 | 2017-12-08 | 重庆沃肯精细化工有限公司 | 一种合成氯法齐明关键中间体n‑(4‑氯苯基)‑1,2‑苯二胺的方法 |
KR20210034587A (ko) * | 2018-06-21 | 2021-03-30 | 셀레스티아 바이오테크 아게 | 아미노 디아릴 에테르 및 아미노 디아릴 에테르 하이드로클로라이드염의 제조 방법 |
EP4085056A1 (en) | 2020-01-03 | 2022-11-09 | Berg LLC | Polycyclic amides as ube2k modulators for treating cancer |
CN116003261A (zh) * | 2022-12-19 | 2023-04-25 | 江苏康恒化工有限公司 | 新型聚氨酯扩链剂2-氨基-2’-氯二苯胺的制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3177221A (en) * | 1963-02-05 | 1965-04-06 | Mcneilab Inc | 2, 1, 3-benzothiadiazoline-2, 2-dioxides |
SK94393A3 (en) * | 1992-09-11 | 1994-08-10 | Thomae Gmbh Dr K | Cyclic derivatives of urea, process for their production and their pharmaceutical agents with the content of those |
ZA966885B (en) * | 1995-08-22 | 1998-02-16 | Du Pont Merck Pharma | Substituted cyclic ureas and derivatives thereof useful as retroviral protease inhibitors. |
GB9825413D0 (en) * | 1998-11-19 | 1999-01-13 | Lilly Co Eli | Pharmaceutical compounds |
AU2001286454B2 (en) * | 2000-08-14 | 2006-09-14 | Ortho-Mcneil Pharmaceutical, Inc. | Substituted pyrazoles |
KR100722207B1 (ko) * | 2001-04-18 | 2007-05-29 | 유로-셀티크 소시에떼 아노뉨 | 노시셉틴 유사체 |
BR0215389A (pt) * | 2001-12-28 | 2004-10-26 | Takeda Chemical Industries Ltd | Agente preventivo ou terapêutico para distúrbio urinário, método para prevenir ou tratar distúrbio urinário, uso de um composto, composto, pró-droga, processo para preparar o composto, medicamento, e, método para triar um composto |
CA2605899C (en) * | 2005-04-26 | 2011-02-08 | Pfizer Limited | Triazole derivatives as vasopressin antagonists |
TW200804325A (en) * | 2005-09-29 | 2008-01-16 | Wyeth Corp | Benzothiadiazolylphenylalkylamine derivatives and methods of their use |
-
2007
- 2007-12-11 CL CL200703590A patent/CL2007003590A1/es unknown
- 2007-12-12 RU RU2009121017/04A patent/RU2009121017A/ru not_active Application Discontinuation
- 2007-12-12 AR ARP070105585A patent/AR064318A1/es unknown
- 2007-12-12 PE PE2007001769A patent/PE20081395A1/es not_active Application Discontinuation
- 2007-12-12 BR BRPI0720289-0A patent/BRPI0720289A2/pt not_active Application Discontinuation
- 2007-12-12 CA CA002671844A patent/CA2671844A1/en not_active Abandoned
- 2007-12-12 WO PCT/US2007/025405 patent/WO2008073459A1/en active Application Filing
- 2007-12-12 US US11/955,018 patent/US7601722B2/en not_active Expired - Fee Related
- 2007-12-12 TW TW096147565A patent/TW200843753A/zh unknown
- 2007-12-12 KR KR1020097014272A patent/KR20090087506A/ko not_active Application Discontinuation
- 2007-12-12 JP JP2009541360A patent/JP2010512401A/ja not_active Withdrawn
- 2007-12-12 EP EP07862811A patent/EP2061776A1/en not_active Withdrawn
- 2007-12-12 CN CNA2007800500208A patent/CN101600701A/zh active Pending
- 2007-12-12 MX MX2009006359A patent/MX2009006359A/es not_active Application Discontinuation
- 2007-12-12 US US11/955,195 patent/US20080161366A1/en not_active Abandoned
- 2007-12-12 US US11/955,204 patent/US20080194654A1/en not_active Abandoned
- 2007-12-12 AU AU2007333593A patent/AU2007333593A1/en not_active Abandoned
-
2009
- 2009-05-29 NO NO20092092A patent/NO20092092L/no not_active Application Discontinuation
- 2009-06-11 ZA ZA200904109A patent/ZA200904109B/xx unknown
- 2009-06-11 SV SV2009003295A patent/SV2009003295A/es unknown
- 2009-06-12 CR CR10866A patent/CR10866A/es not_active Application Discontinuation
- 2009-06-12 EC EC2009009411A patent/ECSP099411A/es unknown
- 2009-08-27 US US12/548,844 patent/US20100029641A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CR10866A (es) | 2009-07-14 |
US20080167303A1 (en) | 2008-07-10 |
TW200843753A (en) | 2008-11-16 |
RU2009121017A (ru) | 2011-01-20 |
US7601722B2 (en) | 2009-10-13 |
MX2009006359A (es) | 2009-06-26 |
PE20081395A1 (es) | 2008-09-17 |
CL2007003590A1 (es) | 2008-02-29 |
CA2671844A1 (en) | 2008-06-19 |
EP2061776A1 (en) | 2009-05-27 |
US20080194654A1 (en) | 2008-08-14 |
BRPI0720289A2 (pt) | 2014-02-04 |
NO20092092L (no) | 2009-08-19 |
AU2007333593A1 (en) | 2008-06-19 |
JP2010512401A (ja) | 2010-04-22 |
WO2008073459A1 (en) | 2008-06-19 |
ZA200904109B (en) | 2010-04-28 |
SV2009003295A (es) | 2009-10-29 |
US20100029641A1 (en) | 2010-02-04 |
US20080161366A1 (en) | 2008-07-03 |
AR064318A1 (es) | 2009-03-25 |
KR20090087506A (ko) | 2009-08-17 |
CN101600701A (zh) | 2009-12-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ECSP099411A (es) | Derivados de aril sulfamida y métodos para su uso | |
WO2008073956A3 (en) | Cyclic sulfonamide derivatives and methods of their use | |
EA200970337A1 (ru) | Ингибиторы котранспортера натрий-глюкозы 2 и способы их применения | |
EA201170161A1 (ru) | 1,2,5-оксадиазолы в качестве ингибиторов индоламин-2,3-диоксигеназы | |
EA200702339A1 (ru) | Замещенные амидные производные в качестве ингибиторов протеинкиназы | |
EA201000642A1 (ru) | 2'-фтор-2'-дезокситетрагидроуридины в качестве ингибиторов цитидиндеаминазы | |
EA201690391A1 (ru) | Селективные модуляторы рецептора сфингозин-1-фосфата и способы хирального синтеза | |
EA201370208A1 (ru) | Формы рифаксимина и их применение | |
EA200971141A1 (ru) | Соединения, активирующие теломеразу, и способы их применения | |
PE20040775A1 (es) | DERIVADOS DE INDOL COMO AGONISTAS DE ADRENORECEPTORES ß2 | |
UY30414A1 (es) | Metano sulfonatos, propano-1-sulfonatos y ciclopropan sulfonatos sustituidos con [2,3,4,8-tetrahidroimidazo-[1,5-al-pirimidin-8-il]-fenilo, composiciones farmacéuticas conteniéndolos y aplicaciones. | |
ATE517882T1 (de) | Chinolinderivate | |
EA200870127A1 (ru) | Полициклические производные аминокислот и способы их применения | |
EA201290191A1 (ru) | N1-ПИРАЗОЛОСПИРОКЕТОНОВЫЕ ИНГИБИТОРЫ АЦЕТИЛ-KoA-КАРБОКСИЛАЗЫ | |
EA200801738A1 (ru) | Пиперидиноилпирролидиновые агонисты меланокортинового рецептора 4 типа | |
PA8601001A1 (es) | Fenacilo 2-hidroxi-3-diaminoalcanos | |
UY30411A1 (es) | Derivados sustituidos del acetato de 2,3,4,-tetrahidroimidazo-[1,5-a]-pirimidin-6-amina, composiciones farmacéuticas y aplicaciones | |
CR10138A (es) | 1h indoles sustituidos por sulfonilo como ligandos para los receptores 5-hidroxitriptamina | |
EA200702468A1 (ru) | Новые производные оксадиазола и их применение в качестве положительных аллостерических модуляторов метаботропных глутаматных рецепторов | |
EA201290329A1 (ru) | Селективные гетрероциклические модуляторы рецептора сфингозин-1-фосфата | |
DE602006010738D1 (de) | Pyrroloä2,3-cüpyridinderivate | |
NI202100012A (es) | Dioxociclobutenilamino-3-hidroxi-picolinamidas n-sustituidas útiles como inhibidores de ccr6 | |
EA200600071A1 (ru) | Производные n-фенилпиперазина и способы профилактики или лечения заболеваний, связанных с 5ht-рецептором | |
EA200702612A1 (ru) | Соединения бензимидазолкарбоксамида в качестве агонистов рецепторов 5-нт | |
ATE466007T1 (de) | 5-substituierte indol-2-carbonsäureamidderivate |