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Application filed by Hoffmann La RochefiledCriticalHoffmann La Roche
Publication of ECSP034870ApublicationCriticalpatent/ECSP034870A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Esta invención se refiere a compuestos que tienen generalmente afinidad por el receptor 5-HT6 y que son representados por la Fórmula I: en donde uno de R5, R6 o R7 es un grupo de fórmula general B, en donde W es un grupo -CH- o un átomo de nitrógeno, y los otros sustituyentes son tal como se definen aquí; o isómeros individuales, mezclas racémicas o no racémicas de isómeros, o sales o solvatos farmacéuticamente aceptables de los mismos. La invención además se refiere a composiciones farmacéuticas que contienen tales compuestos, su uso como agentes terapéuticos, y los métodos de preparación de las mismasThis invention relates to compounds that generally have affinity for the 5-HT6 receptor and that are represented by Formula I: wherein one of R5, R6 or R7 is a group of general formula B, where W is a -CH group - or a nitrogen atom, and the other substituents are as defined herein; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, their use as therapeutic agents, and the methods of preparing them.
ECSP0348702001-06-072003-12-01
NEW INDOL DERIVATIVES AFFINED BY THE 5-HT6 RECEIVER
ECSP034870A
(en)
ANTI-TUMOR AND ANTIVIRAL RENTAL AGENTS, PROCEDURE FOR THEIR PREPARATION, USE OF THE SAME FOR THE MANUFACTURE OF A MEDICINAL PRODUCT AND PHARMACEUTICAL COMPOSITION CONTAINING SUCH AGENTS.
Arylalkyl indoles with serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
Tetracyclic arylcarbonyl indoles with serotonin receptor affinity for use as therapeutic agents, processes for their preparation and pharmaceutical compositions containing them