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EA202191060A1 - ANTI-NPR1 ANTIBODIES AND THEIR APPLICATION - Google Patents

ANTI-NPR1 ANTIBODIES AND THEIR APPLICATION

Info

Publication number
EA202191060A1
EA202191060A1 EA202191060A EA202191060A EA202191060A1 EA 202191060 A1 EA202191060 A1 EA 202191060A1 EA 202191060 A EA202191060 A EA 202191060A EA 202191060 A EA202191060 A EA 202191060A EA 202191060 A1 EA202191060 A1 EA 202191060A1
Authority
EA
Eurasian Patent Office
Prior art keywords
npr1
antibodies
application
bind
npr1 antibodies
Prior art date
Application number
EA202191060A
Other languages
Russian (ru)
Inventor
Майкл Данн
Цзя Су
Джейсон Местейтис
Джеспер Громада
Лори МОРТОН
Original Assignee
Ридженерон Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ридженерон Фармасьютикалз, Инк. filed Critical Ридженерон Фармасьютикалз, Инк.
Priority claimed from PCT/US2019/057033 external-priority patent/WO2020086406A2/en
Publication of EA202191060A1 publication Critical patent/EA202191060A1/en

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  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Настоящее изобретение относится к моноклональным антителам, которые связываются с белком-рецептором натрийуретического пептида 1 (NPR1), и способам их применения. В различных вариантах осуществления изобретения антитела представляют собой полностью человеческие антитела, которые связываются с NPR1. В некоторых вариантах осуществления антитела по изобретению полезны для активации активности NPR1, таким образом обеспечивая средства лечения или профилактики NPR1-ассоциированного заболевания, расстройства или состояния у людей.The present invention relates to monoclonal antibodies that bind to the natriuretic peptide receptor 1 (NPR1) protein and methods of using them. In various embodiments, the antibodies are fully human antibodies that bind to NPR1. In some embodiments, antibodies of the invention are useful for activating NPR1 activity, thereby providing a means of treating or preventing an NPR1-associated disease, disorder, or condition in humans.

EA202191060A 2018-11-05 2019-10-18 ANTI-NPR1 ANTIBODIES AND THEIR APPLICATION EA202191060A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862755720P 2018-11-05 2018-11-05
PCT/US2019/057033 WO2020086406A2 (en) 2018-10-23 2019-10-18 Anti-npr1 antibodies and uses thereof

Publications (1)

Publication Number Publication Date
EA202191060A1 true EA202191060A1 (en) 2021-07-12

Family

ID=77443296

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202191060A EA202191060A1 (en) 2018-11-05 2019-10-18 ANTI-NPR1 ANTIBODIES AND THEIR APPLICATION

Country Status (1)

Country Link
EA (1) EA202191060A1 (en)

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