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EA201891396A1 - Способ получения 2-[4-(4-хлорфенокси)-2-(трифторметил)фенил]-1-(1,2,4-триазол-1-ил)пропан-2-ола - Google Patents

Способ получения 2-[4-(4-хлорфенокси)-2-(трифторметил)фенил]-1-(1,2,4-триазол-1-ил)пропан-2-ола

Info

Publication number
EA201891396A1
EA201891396A1 EA201891396A EA201891396A EA201891396A1 EA 201891396 A1 EA201891396 A1 EA 201891396A1 EA 201891396 A EA201891396 A EA 201891396A EA 201891396 A EA201891396 A EA 201891396A EA 201891396 A1 EA201891396 A1 EA 201891396A1
Authority
EA
Eurasian Patent Office
Prior art keywords
chlorophenoxy
trifluoromethyl
phenyl
producing
ola
Prior art date
Application number
EA201891396A
Other languages
English (en)
Other versions
EA036139B1 (ru
Inventor
Йоахим Гебхардт
Даниэль Зелингер
Манфред Эресманн
Роланд Гётц
Original Assignee
Басф Агро Б.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Басф Агро Б.В. filed Critical Басф Агро Б.В.
Publication of EA201891396A1 publication Critical patent/EA201891396A1/ru
Publication of EA036139B1 publication Critical patent/EA036139B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Настоящее изобретение относится к способу получения 2-[4-(4-хлорфенокси)-2-(трифторметил)фенил]-1-(1,2,4-триазол-1-ил)пропан-2-ола с высокой чистотой. В особенности, оно относится к способу, в котором это соединение эффективно отделяют от его изомера 1,2,4-триазол-4-ила.
EA201891396A 2015-12-18 2016-12-15 Способ получения 2-[4-(4-хлорфенокси)-2-(трифторметил)фенил]-1-(1,2,4-триазол-1-ил)пропан-2-ола EA036139B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15201269 2015-12-18
PCT/EP2016/081113 WO2017102905A1 (en) 2015-12-18 2016-12-15 Method for producing 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol

Publications (2)

Publication Number Publication Date
EA201891396A1 true EA201891396A1 (ru) 2019-01-31
EA036139B1 EA036139B1 (ru) 2020-10-02

Family

ID=54850432

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201891396A EA036139B1 (ru) 2015-12-18 2016-12-15 Способ получения 2-[4-(4-хлорфенокси)-2-(трифторметил)фенил]-1-(1,2,4-триазол-1-ил)пропан-2-ола

Country Status (13)

Country Link
US (1) US11168060B2 (ru)
EP (1) EP3390371B1 (ru)
KR (1) KR102642072B1 (ru)
CN (1) CN108602781A (ru)
BR (1) BR112018010988B1 (ru)
CA (1) CA3006946C (ru)
EA (1) EA036139B1 (ru)
HU (1) HUE047666T2 (ru)
IL (1) IL259609B (ru)
MX (1) MX2018007513A (ru)
PL (1) PL3390371T3 (ru)
UA (1) UA123732C2 (ru)
WO (1) WO2017102905A1 (ru)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3294700T3 (da) 2015-05-08 2020-04-14 Basf Agro Bv Fremgangsmåde til fremstilling af limonen-4-ol
CN107635982A (zh) 2015-05-08 2018-01-26 巴斯夫农业公司 制备萜品油烯环氧化物的方法
DK3472139T3 (da) 2016-06-15 2021-06-28 Basf Agro Bv Fremgangsmåde til epoxidering af en tetrasubstitueret alken
WO2017215928A1 (en) 2016-06-15 2017-12-21 BASF Agro B.V. Process for the epoxidation of a tetrasubstituted alkene
SI3535257T1 (sl) 2016-11-04 2021-04-30 Basf Se Proces za čiščenje prirazolpiridazinov
EP3541788B1 (en) 2016-11-17 2020-09-02 Basf Se Process for the purification of 1-(4-chlorophenyl)pyrazol-3-ol
WO2018172109A1 (en) 2017-03-20 2018-09-27 Basf Se Process for preparing bromotrichloromethane
CN110740995B (zh) 2017-06-14 2023-07-14 巴斯夫农业公司 制备取代苯氧基苯基醇的方法
WO2019086545A1 (en) 2017-11-02 2019-05-09 Basf Se Process for preparing 4-chlorobenzyl propargyl ether
EP3666759A1 (en) 2018-12-10 2020-06-17 Bayer Aktiengesellschaft Preparation of 6-halo-2-(haloalkyl)-3-acylpyridines and intermediates therefor
US11272707B2 (en) 2019-05-31 2022-03-15 Sumitomo Chemical Company, Limited Liquid composition comprising mefentrifluconazole
AU2020286067A1 (en) * 2019-05-31 2022-01-06 Sumitomo Chemical Company, Limited Liquid suspension concentrate formulation comprising mefentrifluconazole
US11317629B2 (en) 2019-05-31 2022-05-03 Sumitomo Chemical Company, Limited Liquid composition comprising mefentrifluconazole
US11033030B2 (en) 2019-05-31 2021-06-15 Sumitomo Chemical Company, Limited Liquid composition comprising mefentrifluconazole
WO2023247239A1 (en) 2022-06-20 2023-12-28 BASF Agro B.V. Method for producing 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009069140A1 (en) 2007-11-28 2009-06-04 Dabur Pharma Limited An improved process for preparation of letrozole and its intermediates
ES2570187T3 (es) * 2011-07-13 2016-05-17 Basf Agro Bv Compuestos fungicidas de 2-[2-halogenoalquil-4-(fenoxi)-fenil]-1-[1,2,4]triazol-1-il-etanol sustituido
EP2943476B1 (en) * 2013-01-09 2019-05-15 BASF Agro B.V. Process for the preparation of substituted oxiranes and triazoles
BR112016014018B8 (pt) * 2013-12-18 2021-10-26 Basf Agro Bv Processo para a preparação dos compostos de cetona (ia), e processo para a preparação dos compostos de triazol de fórmula (ic)
BR112017000304B1 (pt) 2014-07-08 2021-06-29 BASF Agro B.V. Processo para a preparação dos compostos de fórmula ii
EP3310748B1 (en) 2015-06-17 2019-05-29 BASF Agro B.V. Process for the preparation of substituted phenyl ketones

Also Published As

Publication number Publication date
IL259609B (en) 2021-03-25
KR20180094983A (ko) 2018-08-24
MX2018007513A (es) 2018-11-29
BR112018010988A2 (pt) 2018-12-04
HUE047666T2 (hu) 2020-05-28
US11168060B2 (en) 2021-11-09
US20210214319A1 (en) 2021-07-15
CA3006946C (en) 2024-04-16
EP3390371A1 (en) 2018-10-24
WO2017102905A1 (en) 2017-06-22
BR112018010988B1 (pt) 2022-01-18
IL259609A (en) 2018-07-31
EP3390371B1 (en) 2019-11-20
PL3390371T3 (pl) 2020-05-18
KR102642072B1 (ko) 2024-02-28
CA3006946A1 (en) 2017-06-22
EA036139B1 (ru) 2020-10-02
UA123732C2 (uk) 2021-05-26
CN108602781A (zh) 2018-09-28

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG TJ TM