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EA201890729A1 - Настраиваемые варианты доменов суперсемейства иммуноглобулинов и терапия сконструированными клетками - Google Patents

Настраиваемые варианты доменов суперсемейства иммуноглобулинов и терапия сконструированными клетками

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Publication number
EA201890729A1
EA201890729A1 EA201890729A EA201890729A EA201890729A1 EA 201890729 A1 EA201890729 A1 EA 201890729A1 EA 201890729 A EA201890729 A EA 201890729A EA 201890729 A EA201890729 A EA 201890729A EA 201890729 A1 EA201890729 A1 EA 201890729A1
Authority
EA
Eurasian Patent Office
Prior art keywords
proteins
superfamination
immunoglobulins
domains
therapy
Prior art date
Application number
EA201890729A
Other languages
English (en)
Inventor
Райан Свенсон
Майкл Корнакер
Original Assignee
Элпайн Имьюн Сайнс, Инк.
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Publication date
Application filed by Элпайн Имьюн Сайнс, Инк. filed Critical Элпайн Имьюн Сайнс, Инк.
Publication of EA201890729A1 publication Critical patent/EA201890729A1/ru

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Abstract

Предлагаются трансмембранные иммуномодулирующие белки, нуклеиновые кислоты, кодирующие такие белки, и клетки, сконструированные с данными белками. Трансмембранные иммуномодулирующие белки и сконструированные клетки обеспечивают терапевтическую полезность при различных иммунологических и онкологических состояниях. Предлагаются композиции и способы для получения и применения таких белков.
EA201890729A 2015-09-14 2016-09-14 Настраиваемые варианты доменов суперсемейства иммуноглобулинов и терапия сконструированными клетками EA201890729A1 (ru)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562218531P 2015-09-14 2015-09-14
US201662323608P 2016-04-15 2016-04-15
US201662323595P 2016-04-15 2016-04-15
US201662367819P 2016-07-28 2016-07-28
US201662367822P 2016-07-28 2016-07-28
PCT/US2016/051786 WO2017048878A1 (en) 2015-09-14 2016-09-14 Tunable variant immunoglobulin superfamily domains and engineered cell therapy

Publications (1)

Publication Number Publication Date
EA201890729A1 true EA201890729A1 (ru) 2018-09-28

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EA201890729A EA201890729A1 (ru) 2015-09-14 2016-09-14 Настраиваемые варианты доменов суперсемейства иммуноглобулинов и терапия сконструированными клетками

Country Status (12)

Country Link
US (1) US20180256644A1 (ru)
EP (1) EP3350206A1 (ru)
JP (1) JP2018534245A (ru)
KR (1) KR20180054713A (ru)
CN (1) CN108513576A (ru)
AU (1) AU2016323069A1 (ru)
BR (1) BR112018004965A2 (ru)
CA (1) CA2997217A1 (ru)
EA (1) EA201890729A1 (ru)
IL (1) IL258102A (ru)
MX (1) MX2018003144A (ru)
WO (1) WO2017048878A1 (ru)

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