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EA201590887A1 - Композиция - Google Patents

Композиция

Info

Publication number
EA201590887A1
EA201590887A1 EA201590887A EA201590887A EA201590887A1 EA 201590887 A1 EA201590887 A1 EA 201590887A1 EA 201590887 A EA201590887 A EA 201590887A EA 201590887 A EA201590887 A EA 201590887A EA 201590887 A1 EA201590887 A1 EA 201590887A1
Authority
EA
Eurasian Patent Office
Prior art keywords
composition
preparation
methods
relates
present
Prior art date
Application number
EA201590887A
Other languages
English (en)
Inventor
Константин Хольфингер
Сандра Брюк
Original Assignee
Рациофарм Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Рациофарм Гмбх filed Critical Рациофарм Гмбх
Publication of EA201590887A1 publication Critical patent/EA201590887A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Настоящее изобретение относится к композициям, содержащим соединение (I), и способам их получения.
EA201590887A 2012-11-08 2013-11-04 Композиция EA201590887A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261724108P 2012-11-08 2012-11-08
EP12191890.8A EP2730278A1 (en) 2012-11-08 2012-11-08 Composition melt
PCT/EP2013/072960 WO2014072259A1 (en) 2012-11-08 2013-11-04 Composition

Publications (1)

Publication Number Publication Date
EA201590887A1 true EA201590887A1 (ru) 2015-09-30

Family

ID=47146254

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201590887A EA201590887A1 (ru) 2012-11-08 2013-11-04 Композиция

Country Status (5)

Country Link
US (1) US20150306226A1 (ru)
EP (2) EP2730278A1 (ru)
CA (1) CA2890837A1 (ru)
EA (1) EA201590887A1 (ru)
WO (1) WO2014072259A1 (ru)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2014MU01283A (ru) 2014-04-04 2015-10-09 Cadila Healthcare Ltd
WO2015173792A1 (en) * 2014-05-11 2015-11-19 Mapi Pharma Ltd. Amorphous form of apremilast
WO2016135755A1 (en) 2015-02-27 2016-09-01 Mylan Laboratories Limited Amorphous apremilast, premixes thereof, and novel crystalline forms of apremilast
WO2017006354A2 (en) * 2015-07-09 2017-01-12 Sun Pharmaceutical Industries Limited A process for preparation of amorphous apremilast
CN105111127B (zh) * 2015-08-20 2019-02-19 济南纽华医药科技有限公司 阿普斯特无定形及其制备方法
CN105004693A (zh) * 2015-08-22 2015-10-28 南京海纳医药科技有限公司 一种含有阿普斯特活性成分的片剂及其体外溶出测定方法
US9765026B2 (en) * 2015-08-28 2017-09-19 Scinopharm Taiwan, Ltd. Forms of apremilast and the process of making the same
WO2017084597A1 (zh) * 2015-11-19 2017-05-26 常州爱诺新睿医药技术有限公司 一种阿普斯特的无定型物、其制备方法及应用
BR112018076114A2 (pt) 2016-06-15 2019-03-26 Torrent Pharmaceuticals Limited composições tópicas de apremilast
US10196355B2 (en) 2016-06-20 2019-02-05 Johnson Matthey Public Limited Company Forms of apremilast
BR112019015596A2 (pt) * 2017-01-27 2020-03-17 Sarudbhava Formulations Private Limited Composição farmacêutica adequada para administração tópica e método para tratar ou prevenir doenças ou distúrbios dermatológicos
RU2728829C1 (ru) * 2017-02-28 2020-07-31 Канпу Биофармасьютикалз, Лтд. Новое изоиндолиновое производное, включающая его фармацевтическая композиция и его применение
WO2020020101A1 (zh) * 2018-07-22 2020-01-30 上海星叶医药科技有限公司 苯并异硒唑酮胺类化合物及其制备方法和用途
CN111821274A (zh) * 2019-04-15 2020-10-27 上海京新生物医药有限公司 一种阿普斯特缓释制剂及其制备方法
WO2022123597A1 (en) * 2020-12-09 2022-06-16 Apramitha Innovations Private Limited Apremilast ophthalmic compositions
CN115590832B (zh) * 2021-06-28 2023-10-24 山东新时代药业有限公司 一种法罗培南钠片及其制备方法
EP4183389A1 (en) 2021-11-18 2023-05-24 KRKA, d.d., Novo mesto Pharmaceutical composition comprising apremilast

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6020358A (en) 1998-10-30 2000-02-01 Celgene Corporation Substituted phenethylsulfones and method of reducing TNFα levels
RU2471782C2 (ru) 2008-03-27 2013-01-10 Селджин Корпорейшн Твердые формы, содержащие (+)-2-[1-(3-этокси-4-метоксифенил)-2-метилсульфонилэтил]-4-ацетиламиноизоиндолин-1, 3-дион, их композиции и применение
EP2133068A1 (de) * 2008-06-13 2009-12-16 Ratiopharm GmbH Verfahren zur Auswahl eines geeigneten Hilfsstoffs für die Herstellung von festen Dispersionen für pharmazeutische Formulierungen
US20120320153A1 (en) 2010-02-25 2012-12-20 Jesus Barcons-Palau Disparity estimation for stereoscopic subtitling
MX354210B (es) * 2010-12-16 2018-02-16 Celgene Corp Formas farmaceuticas orales de liberacion controlada de farmacos escasamente solubles y los usos de estas.

Also Published As

Publication number Publication date
WO2014072259A1 (en) 2014-05-15
US20150306226A1 (en) 2015-10-29
CA2890837A1 (en) 2014-05-15
EP2916822A1 (en) 2015-09-16
EP2730278A1 (en) 2014-05-14

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